BRPI9813001B1 - processo de fabricação de derivados de camptotecina. - Google Patents
processo de fabricação de derivados de camptotecina.Info
- Publication number
- BRPI9813001B1 BRPI9813001B1 BRPI9813001-3A BRPI9813001A BRPI9813001B1 BR PI9813001 B1 BRPI9813001 B1 BR PI9813001B1 BR PI9813001 A BRPI9813001 A BR PI9813001A BR PI9813001 B1 BRPI9813001 B1 BR PI9813001B1
- Authority
- BR
- Brazil
- Prior art keywords
- manufacturing process
- camptothecin derivatives
- camptothecin
- derivatives
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19970031710 | 1997-07-09 | ||
| PCT/KR1998/000199 WO1999002530A1 (en) | 1997-07-09 | 1998-07-08 | A process of manufacturing camptothecin derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI9813001A BRPI9813001A (pt) | 2000-08-15 |
| BRPI9813001B1 true BRPI9813001B1 (pt) | 2011-11-01 |
| BRPI9813001B8 BRPI9813001B8 (pt) | 2021-07-06 |
Family
ID=19513816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9813001-3 BRPI9813001B8 (pt) | 1997-07-09 | 1998-07-08 | processo de fabricação de derivados de camptotecina. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6310207B1 (pt) |
| KR (1) | KR100266743B1 (pt) |
| AU (1) | AU8244998A (pt) |
| BR (1) | BRPI9813001B8 (pt) |
| CH (1) | CH693877A8 (pt) |
| ES (1) | ES2163365B2 (pt) |
| IN (1) | IN189180B (pt) |
| RU (1) | RU2181122C2 (pt) |
| WO (1) | WO1999002530A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7109165B2 (en) * | 2001-05-18 | 2006-09-19 | Sirna Therapeutics, Inc. | Conjugates and compositions for cellular delivery |
| DK3946464T3 (da) | 2019-03-29 | 2022-10-31 | Medimmune Ltd | Forbindelser og konjugater deraf |
| CN114341162A (zh) | 2019-07-10 | 2022-04-12 | 赛博克萨2公司 | 作为治疗剂的细胞毒素的肽缀合物 |
| PH12022550037A1 (en) | 2019-07-10 | 2023-04-12 | Cybrexa 3 Inc | Peptide conjugates of microtubule-targeting agents as therapeutics |
| CN116478175A (zh) * | 2022-09-09 | 2023-07-25 | 杭州爱科瑞思生物医药有限公司 | 喜树碱-7-乙基胺衍生物及其制备方法和应用 |
| CN116478051B (zh) * | 2023-04-13 | 2024-06-21 | 戊言医药科技（上海）有限公司 | 一种贝洛替康盐酸盐及其关键中间体的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939255A (en) * | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| HU213136B (en) * | 1990-08-14 | 1997-02-28 | Kyorin Seiyaku Kk | Process for producing fluoroethyl camptothecin derivatives and pharmaceutical compositions containing them |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| KR960029336A (ko) * | 1995-01-09 | 1996-08-17 | 김충환 | 캄토테신 유도체, 그의 제조 방법 및 이를 함유하는 항암제 |
-
1998
- 1998-07-06 IN IN1921DE1998 patent/IN189180B/en unknown
- 1998-07-07 KR KR1019980027267A patent/KR100266743B1/ko active IP Right Grant
- 1998-07-08 CH CH00031/00A patent/CH693877A8/de not_active IP Right Cessation
- 1998-07-08 US US09/462,271 patent/US6310207B1/en not_active Expired - Lifetime
- 1998-07-08 AU AU82449/98A patent/AU8244998A/en not_active Abandoned
- 1998-07-08 WO PCT/KR1998/000199 patent/WO1999002530A1/en active IP Right Grant
- 1998-07-08 RU RU2000100980/04A patent/RU2181122C2/ru active
- 1998-07-08 BR BRPI9813001-3 patent/BRPI9813001B8/pt not_active IP Right Cessation
- 1998-07-08 ES ES009950083A patent/ES2163365B2/es not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999002530A1 (en) | 1999-01-21 |
| US6310207B1 (en) | 2001-10-30 |
| AU8244998A (en) | 1999-02-08 |
| CH693877A8 (de) | 2004-05-28 |
| BRPI9813001A (pt) | 2000-08-15 |
| BRPI9813001B8 (pt) | 2021-07-06 |
| KR19990013649A (ko) | 1999-02-25 |
| ES2163365A1 (es) | 2002-01-16 |
| CH693877A5 (de) | 2004-03-31 |
| KR100266743B1 (ko) | 2000-12-01 |
| ES2163365B2 (es) | 2002-11-01 |
| IN189180B (pt) | 2003-01-04 |
| RU2181122C2 (ru) | 2002-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/11/2011, OBSERVADAS AS CONDICOES LEGAIS. ONDE DE LE: FORMALDEHYDE, PARAFORMALDEIDRO, DIMETHYLFORMAMIDE E DIMETHYL; LEIA-SE: FORMALDEIDO, PARAFORMALDEIDO, DIMETILFORMAMIDA E DIMETIL. |
|
| B25D | Requested change of name of applicant approved | ||
| B25G | Requested change of headquarter approved | ||
| B25A | Requested transfer of rights approved | ||
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/07/98, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |
|
| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 08.07.2018 |