BRPI0914662A2 - derivados de triazinona substituída - Google Patents

derivados de triazinona substituída

Info

Publication number: BRPI0914662A2
Authority: BR; Brazil
Prior art keywords: triazinone derivatives; substituted; substituted triazinone; derivatives; triazinone
Prior art date: 2008-06-26

Application number

BRPI0914662A

Other languages

English (en)

Inventor

Alistair Lochead

Mourad Saady

Philippe Yaiche

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-26

Filing date

2009-06-25

Publication date

2015-10-20

2009-06-25 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2015-10-20 Publication of BRPI0914662A2 publication Critical patent/BRPI0914662A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Hematology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Tropical Medicine & Parasitology (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Endocrinology (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)

BRPI0914662A 2008-06-26 2009-06-25 derivados de triazinona substituída BRPI0914662A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08290617A EP2138488A1 (en)	2008-06-26	2008-06-26	4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
PCT/IB2009/006463 WO2009156860A2 (en)	2008-06-26	2009-06-25	Substituted triazinone derivatives

Publications (1)

Publication Number	Publication Date
BRPI0914662A2 true BRPI0914662A2 (pt)	2015-10-20

Family

ID=39832570

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0914662A BRPI0914662A2 (pt)	2008-06-26	2009-06-25	derivados de triazinona substituída

Country Status (23)

Country	Link
US (1)	US8592580B2 (pt)
EP (2)	EP2138488A1 (pt)
JP (1)	JP5581318B2 (pt)
KR (1)	KR20110025219A (pt)
CN (1)	CN102137854A (pt)
AR (1)	AR072227A1 (pt)
AT (1)	ATE538114T1 (pt)
AU (1)	AU2009263846A1 (pt)
BR (1)	BRPI0914662A2 (pt)
CA (1)	CA2729115A1 (pt)
CY (1)	CY1112642T1 (pt)
DK (1)	DK2321295T3 (pt)
EA (1)	EA201170095A1 (pt)
ES (1)	ES2379220T3 (pt)
IL (1)	IL210174A0 (pt)
MX (1)	MX2010014235A (pt)
NZ (1)	NZ590116A (pt)
PL (1)	PL2321295T3 (pt)
PT (1)	PT2321295E (pt)
SI (1)	SI2321295T1 (pt)
TW (1)	TW201004935A (pt)
WO (1)	WO2009156860A2 (pt)
ZA (1)	ZA201100026B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2138493A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138498A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted tricyclic derivatives against neurodegenerative diseases
EP2138485A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138492A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidin-4-one derivatives
EP2138495A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
EP2138494A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
JP6304492B2 (ja) *	2012-03-30	2018-04-04	日産化学工業株式会社	トリアジノン化合物及びｔ型カルシウムチャネル阻害剤
SI3459942T1 (sl) *	2012-04-24	2021-05-31	Vertex Pharmaceuticals Incorporated	Inhibitorji DNA-PK
SG11201507203RA (en)	2013-03-12	2015-10-29	Vertex Pharma	Dna-pk inhibitors
JP6408569B2 (ja)	2013-10-17	2018-10-17	バーテックスファーマシューティカルズインコーポレイテッドＶｅｒｔｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃｏｒｐｏｒａｔｅｄ	Ｄｎａ−ｐｋ阻害剤としての（ｓ）−ｎ−メチル−８−（１−（（２’−メチル−［４，５’−ビピリミジン］−６−イル）アミノ）プロパン−２−イル）キノリン−４−カルボキサミドおよびその重水素化誘導体の共結晶
TWI651310B (zh) *	2014-02-20	2019-02-21	日商日本煙草產業股份有限公司	三化合物及其醫藥用途
EP3154953B1 (en) *	2014-06-13	2018-04-04	Fondazione Istituto Italiano di Tecnologia	Dual inhibitor compounds for use in the treatment of neurodegenerative disorders and alzheimer's disease
SG11201800698VA (en) *	2015-08-17	2018-03-28	Japan Tobacco Inc	Hydroxytriazine compound and medical use thereof
US11110108B2 (en)	2016-09-27	2021-09-07	Vertex Pharmaceuticals Incorporated	Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors
WO2022152138A1 (zh) *	2021-01-15	2022-07-21	中国医药研究开发中心有限公司	稠和杂环类化合物及其制备方法和医药用途

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EP1136484A1 (en) *	2000-03-23	2001-09-26	Sanofi-Synthelabo	2-(Arylalkylamino)pyrimidone derivatives
CA2665516A1 (en)	2001-04-26	2002-11-07	Daiichi Pharmaceutical Co., Ltd.	Drug efflux pump inhibitor
MXPA04002632A (es)	2001-09-21	2004-07-08	Mitsubishin Pharma Corp	Derivados de 2-pirimidinil-6,7,8,9-tetrahidropirimido-[1,2-a] pirimidin-4-ona y 7-pirimidinil-2,3. dihidroimidazo [1,2-a] pirimidim-5 (1h)-ona substituidos para desordenes neurodegenerativos.
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EP1454909B1 (en)	2003-03-07	2008-08-20	Sanofi Aventis	8'-pyridinyl-dihydrospiro (cycloalkyl) -pyrimido (1,2-a) pyrimidin-6-one and 8'-pyrimidinyl-dihydrospiro (cycloalkyl) pyrimido (1,2-a) pyrimidin-6 derivatives -one and their use against neurodegenerative diseases
EP1460076A1 (en)	2003-03-21	2004-09-22	Sanofi-Synthelabo	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
EA017545B1 (ru) *	2005-06-30	2013-01-30	Янссен Фармацевтика Н.В.	Циклические анилино-пиридинотриазины в качестве ингибиторов gsk-3
EP1790649A1 (en)	2005-11-21	2007-05-30	Sanofi-Aventis	Substituted bicyclic pyrimidone derivatives
ATE530540T1 (de) *	2006-08-23	2011-11-15	Pfizer Prod Inc	Pyrimidonverbindungen als gsk-3-inhibitoren
US20110039893A1 (en) *	2006-10-11	2011-02-17	Takeda Pharmaceutical Company Limited	Gsk-3beta inhibitor
EP1992624A1 (en) *	2007-05-16	2008-11-19	Sanofi-Aventis	Heteroarylamide pyrimidone compounds
EP2138492A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidin-4-one derivatives
EP2138485A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138494A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
EP2138493A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138495A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives

2008
- 2008-06-26 EP EP08290617A patent/EP2138488A1/en not_active Withdrawn
2009
- 2009-06-24 TW TW098121235A patent/TW201004935A/zh unknown
- 2009-06-24 AR ARP090102315A patent/AR072227A1/es unknown
- 2009-06-25 KR KR1020117001908A patent/KR20110025219A/ko not_active Withdrawn
- 2009-06-25 PT PT09769671T patent/PT2321295E/pt unknown
- 2009-06-25 MX MX2010014235A patent/MX2010014235A/es not_active Application Discontinuation
- 2009-06-25 AU AU2009263846A patent/AU2009263846A1/en not_active Abandoned
- 2009-06-25 CA CA2729115A patent/CA2729115A1/en not_active Abandoned
- 2009-06-25 WO PCT/IB2009/006463 patent/WO2009156860A2/en active Application Filing
- 2009-06-25 DK DK09769671.0T patent/DK2321295T3/da active
- 2009-06-25 PL PL09769671T patent/PL2321295T3/pl unknown
- 2009-06-25 JP JP2011515667A patent/JP5581318B2/ja not_active Expired - Fee Related
- 2009-06-25 AT AT09769671T patent/ATE538114T1/de active
- 2009-06-25 NZ NZ590116A patent/NZ590116A/en not_active IP Right Cessation
- 2009-06-25 SI SI200930201T patent/SI2321295T1/sl unknown
- 2009-06-25 BR BRPI0914662A patent/BRPI0914662A2/pt not_active IP Right Cessation
- 2009-06-25 EP EP09769671A patent/EP2321295B1/en active Active
- 2009-06-25 CN CN2009801334844A patent/CN102137854A/zh active Pending
- 2009-06-25 ES ES09769671T patent/ES2379220T3/es active Active
- 2009-06-25 EA EA201170095A patent/EA201170095A1/ru unknown
2010
- 2010-12-15 US US12/968,935 patent/US8592580B2/en not_active Expired - Fee Related
- 2010-12-22 IL IL210174A patent/IL210174A0/en unknown
2011
- 2011-01-03 ZA ZA2011/00026A patent/ZA201100026B/en unknown
2012
- 2012-03-16 CY CY20121100288T patent/CY1112642T1/el unknown

Also Published As

Publication number	Publication date
AR072227A1 (es)	2010-08-11
CN102137854A (zh)	2011-07-27
TW201004935A (en)	2010-02-01
EP2321295B1 (en)	2011-12-21
KR20110025219A (ko)	2011-03-09
EA201170095A1 (ru)	2011-08-30
CY1112642T1 (el)	2016-02-10
ES2379220T3 (es)	2012-04-23
PL2321295T3 (pl)	2012-06-29
ATE538114T1 (de)	2012-01-15
JP2011525905A (ja)	2011-09-29
US8592580B2 (en)	2013-11-26
DK2321295T3 (da)	2012-04-10
JP5581318B2 (ja)	2014-08-27
IL210174A0 (en)	2011-03-31
CA2729115A1 (en)	2009-12-30
WO2009156860A3 (en)	2010-03-04
AU2009263846A1 (en)	2009-12-30
EP2138488A1 (en)	2009-12-30
US20110144114A1 (en)	2011-06-16
PT2321295E (pt)	2012-03-23
MX2010014235A (es)	2011-06-24
WO2009156860A2 (en)	2009-12-30
ZA201100026B (en)	2012-04-25
EP2321295A2 (en)	2011-05-18
SI2321295T1 (sl)	2012-04-30
NZ590116A (en)	2011-10-28

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DK2340021T3 (da)	2012-12-10	Substituerede pyrrolidin-2-carboxamider
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EP2336132A4 (en)	2012-03-21	MORPHOLINPURINDERIVAT
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