BRPI0909030A2 - composições farmacêuticas de liberação modificada compreendendo micofenolato e processos para as mesmas. - Google Patents
composições farmacêuticas de liberação modificada compreendendo micofenolato e processos para as mesmas.Info
- Publication number
- BRPI0909030A2 BRPI0909030A2 BRPI0909030A BRPI0909030A BRPI0909030A2 BR PI0909030 A2 BRPI0909030 A2 BR PI0909030A2 BR PI0909030 A BRPI0909030 A BR PI0909030A BR PI0909030 A BRPI0909030 A BR PI0909030A BR PI0909030 A2 BRPI0909030 A2 BR PI0909030A2
- Authority
- BR
- Brazil
- Prior art keywords
- mycophenolate
- pharmaceutical compositions
- modified release
- release pharmaceutical
- processes therefor
- Prior art date
Links
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title 1
- 229940014456 mycophenolate Drugs 0.000 title 1
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN549DE2008 | 2008-03-05 | ||
PCT/IN2009/000148 WO2009110005A2 (en) | 2008-03-05 | 2009-03-04 | Modified release pharmaceutical compositions comprising mycophenolate and processes thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0909030A2 true BRPI0909030A2 (pt) | 2018-03-13 |
Family
ID=40863399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0909030A BRPI0909030A2 (pt) | 2008-03-05 | 2009-03-04 | composições farmacêuticas de liberação modificada compreendendo micofenolato e processos para as mesmas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20110008426A1 (pt) |
EP (1) | EP2262483A2 (pt) |
JP (1) | JP2011513391A (pt) |
KR (1) | KR20100126465A (pt) |
CN (1) | CN101969931A (pt) |
AU (1) | AU2009220779A1 (pt) |
BR (1) | BRPI0909030A2 (pt) |
CA (1) | CA2717456A1 (pt) |
EA (1) | EA201071035A1 (pt) |
MX (1) | MX2010009704A (pt) |
WO (1) | WO2009110005A2 (pt) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20080076743A1 (en) | 2006-08-03 | 2008-03-27 | Nitec Pharma Ag | Delayed-Release Glucocorticoid treatment of Rheumatoid Disease |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
JP5774853B2 (ja) | 2008-01-25 | 2015-09-09 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 医薬投薬形 |
NZ588863A (en) | 2008-05-09 | 2012-08-31 | Gruenenthal Chemie | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
PL2456424T3 (pl) | 2009-07-22 | 2013-12-31 | Gruenenthal Gmbh | Stabilizowana przed utlenianiem odporna na naruszenie postać dawkowania |
PL2456427T3 (pl) | 2009-07-22 | 2015-07-31 | Gruenenthal Gmbh | Wytłaczana na gorąco postać dawki o kontrolowanym uwalnianiu |
US20120141584A1 (en) * | 2009-08-26 | 2012-06-07 | Aptapharma, Inc. | Multilayer Minitablets |
WO2011051967A2 (en) * | 2009-10-23 | 2011-05-05 | Alkem Laboratories Ltd | Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof |
AU2011297901B2 (en) | 2010-09-02 | 2014-07-31 | Grunenthal Gmbh | Tamper resistant dosage form comprising inorganic salt |
KR20130137627A (ko) | 2010-09-02 | 2013-12-17 | 그뤼넨탈 게엠베하 | 음이온성 중합체를 포함하는 내변조성 투여형 |
ES2648129T3 (es) | 2011-07-29 | 2017-12-28 | Grünenthal GmbH | Pastilla a prueba de manipulación que proporciona una liberación inmediata de un medicamento |
PT2736495T (pt) | 2011-07-29 | 2017-11-30 | Gruenenthal Gmbh | Comprimido resistente à adulteração proporcionando libertação imediata de fármaco |
EP2819656A1 (en) | 2012-02-28 | 2015-01-07 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
AR090695A1 (es) | 2012-04-18 | 2014-12-03 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
TW201503912A (zh) * | 2013-03-19 | 2015-02-01 | Novartis Ag | 包含癌莫事(everolimus)之醫藥組合物 |
MX2015016254A (es) | 2013-05-29 | 2016-04-20 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal. |
EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
KR20160031526A (ko) | 2013-07-12 | 2016-03-22 | 그뤼넨탈 게엠베하 | 에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형 |
AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
MX2016014738A (es) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol. |
AU2015266117A1 (en) | 2014-05-26 | 2016-11-24 | Grunenthal Gmbh | Multiparticles safeguarded against ethanolic dose-dumping |
JP2018517676A (ja) | 2015-04-24 | 2018-07-05 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時放出および溶媒抽出に対する耐性を有する改変防止製剤 |
JP6857141B2 (ja) | 2015-05-20 | 2021-04-14 | ノバルティス アーゲー | エベロリムスとダクトリシブとの薬学的組合せ |
TWI722988B (zh) * | 2015-06-05 | 2021-04-01 | 瑩碩生技醫藥股份有限公司 | 緩釋性醫藥組合物及其製備方法 |
US10842750B2 (en) | 2015-09-10 | 2020-11-24 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
JP7158284B2 (ja) * | 2016-04-21 | 2022-10-21 | ヴァルキュリア アクチアボラグ | がんを前処置するための組成物および方法 |
MX2019006090A (es) | 2016-11-23 | 2019-08-21 | Novartis Ag | Metodos para mejorar la respuesta inmune con everolimus, dactolisib o ambos. |
EP3595639A2 (en) | 2017-03-13 | 2020-01-22 | Okava Pharmaceuticals, Inc. | Methods and compositions for delivering mycophenolic acid active agents to non-human mammals |
CN108066322A (zh) * | 2018-02-01 | 2018-05-25 | 宁波蒙曼生物科技有限公司 | 一种吗替麦考酚酯缓释胶囊及其制备方法 |
US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
US10835489B2 (en) | 2018-03-09 | 2020-11-17 | University Of Saskatchewan | Modified release formulations of mycophenolate mofetil |
JP2022506007A (ja) * | 2018-09-07 | 2022-01-17 | オカヴァ ファーマシューティカルズ, インコーポレイテッド | ミコフェノール酸活性剤を非ヒト哺乳動物に送達するための方法および組成物 |
JP6795238B1 (ja) * | 2020-06-12 | 2020-12-02 | 竹本油脂株式会社 | 合成繊維用処理剤の製造方法、合成繊維用処理剤、合成繊維、及び合成繊維の製造方法 |
CN114569570B (zh) * | 2022-03-15 | 2023-03-24 | 浙江长典药物技术开发有限公司 | 一种吗替麦考酚酯及制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1258143B (it) * | 1992-09-11 | 1996-02-20 | Alfa Wassermann Spa | Compresse a cessione programmata contenenti naproxen |
GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
US6913768B2 (en) * | 2002-09-24 | 2005-07-05 | Shire Laboratories, Inc. | Sustained release delivery of amphetamine salts |
HRP20030324A2 (en) * | 2003-04-24 | 2005-02-28 | Pliva-Istra�iva�ki institut d.o.o. | Compounds of antiinflammatory effect |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
GB0419355D0 (en) * | 2004-08-31 | 2004-09-29 | Novartis Ag | Organic compounds |
EP2322146B1 (en) * | 2004-09-27 | 2012-12-12 | Sigmoid Pharma Limited | Microcapsule formulations comprising two pharmaceutically active ingredients |
AU2007214784A1 (en) * | 2006-02-13 | 2007-08-23 | Novartis Ag | High dosage of mycophenolic acid (MPA) |
-
2009
- 2009-03-04 CA CA2717456A patent/CA2717456A1/en not_active Abandoned
- 2009-03-04 KR KR1020107022011A patent/KR20100126465A/ko not_active Withdrawn
- 2009-03-04 US US12/920,512 patent/US20110008426A1/en not_active Abandoned
- 2009-03-04 EA EA201071035A patent/EA201071035A1/ru unknown
- 2009-03-04 EP EP09717394A patent/EP2262483A2/en not_active Withdrawn
- 2009-03-04 WO PCT/IN2009/000148 patent/WO2009110005A2/en active Application Filing
- 2009-03-04 MX MX2010009704A patent/MX2010009704A/es not_active Application Discontinuation
- 2009-03-04 CN CN2009801078161A patent/CN101969931A/zh active Pending
- 2009-03-04 JP JP2010549258A patent/JP2011513391A/ja not_active Withdrawn
- 2009-03-04 BR BRPI0909030A patent/BRPI0909030A2/pt not_active IP Right Cessation
- 2009-03-04 AU AU2009220779A patent/AU2009220779A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101969931A (zh) | 2011-02-09 |
KR20100126465A (ko) | 2010-12-01 |
WO2009110005A2 (en) | 2009-09-11 |
AU2009220779A1 (en) | 2009-09-11 |
EP2262483A2 (en) | 2010-12-22 |
WO2009110005A3 (en) | 2010-10-14 |
US20110008426A1 (en) | 2011-01-13 |
JP2011513391A (ja) | 2011-04-28 |
MX2010009704A (es) | 2010-12-20 |
CA2717456A1 (en) | 2009-09-11 |
EA201071035A1 (ru) | 2011-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A, 8A E 9A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |