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BRPI0807613A2 - Ativação de antígeno humano presente em células através de clec-6 - Google Patents

Ativação de antígeno humano presente em células através de clec-6

Info

Publication number
BRPI0807613A2
BRPI0807613A2 BRPI0807613-8A2A BRPI0807613A BRPI0807613A2 BR PI0807613 A2 BRPI0807613 A2 BR PI0807613A2 BR PI0807613 A BRPI0807613 A BR PI0807613A BR PI0807613 A2 BRPI0807613 A2 BR PI0807613A2
Authority
BR
Brazil
Prior art keywords
clec
cells
human antigen
antigen activation
activation present
Prior art date
Application number
BRPI0807613-8A2A
Other languages
English (en)
Inventor
Jacques F Banchereau
Dapeng Li
Sandra Zurawski
Gerard Zurawski
Sangkon Oh
Original Assignee
Baylor Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Inst filed Critical Baylor Res Inst
Publication of BRPI0807613A2 publication Critical patent/BRPI0807613A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14Peptides being immobilised on, or in, an inorganic carrier
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0807613-8A2A 2007-02-23 2008-02-22 Ativação de antígeno humano presente em células através de clec-6 BRPI0807613A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89141807P 2007-02-23 2007-02-23
PCT/US2008/054785 WO2008103947A2 (en) 2007-02-23 2008-02-22 Activation of human antigen-presenting cells through clec-6

Publications (1)

Publication Number Publication Date
BRPI0807613A2 true BRPI0807613A2 (pt) 2014-06-10

Family

ID=39710781

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807613-8A2A BRPI0807613A2 (pt) 2007-02-23 2008-02-22 Ativação de antígeno humano presente em células através de clec-6

Country Status (14)

Country Link
US (1) US20080254047A1 (pt)
EP (1) EP2129692A4 (pt)
JP (1) JP2010519313A (pt)
KR (1) KR20090118981A (pt)
CN (2) CN101668777A (pt)
AU (1) AU2008218184B2 (pt)
BR (1) BRPI0807613A2 (pt)
CA (1) CA2717656A1 (pt)
IL (2) IL200526A0 (pt)
MX (1) MX2009008918A (pt)
NZ (2) NZ595319A (pt)
TW (1) TW200900078A (pt)
WO (1) WO2008103947A2 (pt)
ZA (1) ZA200906618B (pt)

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KR20130036246A (ko) * 2010-05-07 2013-04-11 베일러 리서치 인스티튜트 사람 cd8+ t 세포의 수지상 세포 면역수용체(dcir)-매개 교차프라이밍
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
MX359070B (es) 2010-12-01 2018-09-13 Alderbio Holdings Llc Composiciones anti-ngf y uso de las mismas.
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
JP6262218B2 (ja) * 2012-06-14 2018-01-17 エラスムス ユニバーシティ メディカルセンター ロッテルダムErasmus University Medical Center Rotterdam 微小残存病変を検出するための方法、試薬およびキット。
SI2928923T1 (sl) * 2012-12-10 2020-03-31 Biogen Ma Inc. Protitelesa proti antigenu 2 dendritičnih celic v krvi in njihova uporaba
AU2014302082B2 (en) 2013-06-28 2019-08-08 Baylor Research Institute Dendritic cell ASGPR targeting immunotherapeutics for multiple sclerosis
EP3094652B1 (en) 2014-01-13 2021-09-29 Baylor Research Institute Novel vaccines against hpv and hpv-related diseases
SG11201607746QA (en) 2014-03-21 2016-10-28 Abbvie Inc Anti-egfr antibodies and antibody drug conjugates
US11034749B2 (en) 2015-07-28 2021-06-15 The Trustees Of The University Of Pennsylvania Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof
CN105510598A (zh) * 2015-12-31 2016-04-20 中国科学院海洋研究所 长牡蛎CgNatterin-3重组蛋白的应用
WO2017201635A1 (zh) * 2016-05-23 2017-11-30 蔡胜和 透明质酸酶的细胞表达及其在实体瘤细胞治疗中的应用
BR112018075630A2 (pt) 2016-06-08 2019-03-19 Abbvie Inc. anticorpos anti-cd98 e conjugados de fármaco de anticorpo
CA3027044A1 (en) 2016-06-08 2017-12-14 Abbvie Inc. Anti-b7-h3 antibodies and antibody drug conjugates
MX2018015285A (es) 2016-06-08 2019-09-18 Abbvie Inc Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco.
ES2861499T3 (es) 2016-06-08 2021-10-06 Abbvie Inc Anticuerpos anti-B7-H3 y conjugados anticuerpo-fármaco
KR102590454B1 (ko) 2016-07-07 2023-10-17 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 항체-애쥬번트 접합체
CA3039348C (en) * 2016-10-21 2023-09-05 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for promoting t cells response
CN110234348B (zh) 2016-12-16 2024-06-25 蓝鳍生物医药公司 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法
EP3612567B1 (en) 2017-04-19 2024-09-11 Bluefin Biomedicine, Inc. Anti-vtcn1 antibodies and antibody drug conjugates
CN118994394A (zh) 2017-06-12 2024-11-22 蓝鳍生物医药公司 抗-il1rap抗体和抗体药物缀合物
AU2018290880A1 (en) * 2017-06-28 2020-01-16 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for Dectin-2 stimulation and cancer immunotherapy
CN117004573A (zh) * 2017-12-13 2023-11-07 苏州康聚生物科技有限公司 一种包含肿瘤抗原识别受体的免疫细胞及其应用
JP2022525594A (ja) 2019-03-15 2022-05-18 ボルト バイオセラピューティクス、インコーポレーテッド Her2を標的とする免疫結合体
CN110373385A (zh) * 2019-07-12 2019-10-25 赛德特生物科技开发有限公司 改善神经细胞功能的免疫细胞培养基及其制备方法与应用
MX2022015062A (es) 2020-06-04 2023-04-10 Carisma Therapeutics Inc Nuevas construcciones para receptores de antígenos quiméricos.
AR124681A1 (es) 2021-01-20 2023-04-26 Abbvie Inc Conjugados anticuerpo-fármaco anti-egfr
CN114315990B (zh) * 2022-03-10 2022-05-27 北京康乐卫士生物技术股份有限公司 新型冠状病毒特异性单克隆抗体的制备及其应用
WO2025027529A1 (en) 2023-07-31 2025-02-06 Advesya Anti-il-1rap antibody drug conjugates and methods of use thereof
WO2025126157A1 (en) 2023-12-15 2025-06-19 Advesya Anti-il-1rap binding domains and antibody-drug conjugates thereof

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NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3949064A (en) * 1973-10-26 1976-04-06 Baxter Laboratories, Inc. Method of detecting antigens or antibodies
US4174384A (en) * 1975-06-30 1979-11-13 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US20040258688A1 (en) * 1995-01-31 2004-12-23 Daniel Hawiger Enhanced antigen delivery and modulation of the immune response therefrom
US6046158A (en) * 1996-12-20 2000-04-04 Board Of Regents The University Of Texas Systems Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof
US6541011B2 (en) * 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
US5945308A (en) * 1998-04-03 1999-08-31 Incyte Pharmaceuticals, Inc. Human oxidized LDL receptor
AU2003213640A1 (en) * 2002-02-28 2003-09-16 Corixa Corporation Methods of modulating dendritic cells using adjuvants
US20040091503A1 (en) * 2002-08-20 2004-05-13 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
US7666596B2 (en) * 2005-05-23 2010-02-23 University Of Alberta Tissue rejection
BRPI0807344A2 (pt) * 2007-02-02 2014-05-20 Baylor Res Inst Antígenos multivariáveis complexados com anticorpo monoclonal humanizado de direcionamento

Also Published As

Publication number Publication date
NZ595319A (en) 2012-09-28
AU2008218184B2 (en) 2013-01-10
IL216778A0 (en) 2012-01-31
TW200900078A (en) 2009-01-01
EP2129692A4 (en) 2010-12-15
JP2010519313A (ja) 2010-06-03
ZA200906618B (en) 2010-06-30
EP2129692A2 (en) 2009-12-09
IL200526A0 (en) 2010-04-29
WO2008103947A3 (en) 2008-11-27
CN101668777A (zh) 2010-03-10
US20080254047A1 (en) 2008-10-16
NZ579238A (en) 2012-04-27
CA2717656A1 (en) 2008-08-28
AU2008218184A1 (en) 2008-08-28
CN102586186A (zh) 2012-07-18
WO2008103947A2 (en) 2008-08-28
MX2009008918A (es) 2009-09-14
KR20090118981A (ko) 2009-11-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2277 DE 26/08/2014.