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BRPI0519424A2 - composiÇÕes e mÉtodos para tratamento de distérbios de proliferaÇço celular - Google Patents

composiÇÕes e mÉtodos para tratamento de distérbios de proliferaÇço celular

Info

Publication number
BRPI0519424A2
BRPI0519424A2 BRPI0519424-5A BRPI0519424A BRPI0519424A2 BR PI0519424 A2 BRPI0519424 A2 BR PI0519424A2 BR PI0519424 A BRPI0519424 A BR PI0519424A BR PI0519424 A2 BRPI0519424 A2 BR PI0519424A2
Authority
BR
Brazil
Prior art keywords
methods
cell proliferation
compositions
proliferation disorders
treating cell
Prior art date
Application number
BRPI0519424-5A
Other languages
English (en)
Inventor
David G Hangauer
Original Assignee
Kinex Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36615518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0519424(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kinex Pharmaceuticals Llc filed Critical Kinex Pharmaceuticals Llc
Publication of BRPI0519424A2 publication Critical patent/BRPI0519424A2/pt
Publication of BRPI0519424B1 publication Critical patent/BRPI0519424B1/pt
Publication of BRPI0519424B8 publication Critical patent/BRPI0519424B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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Abstract

COMPOSIÇÕES E MÉTODOS PARA TRATAMENTO DE DISTéRBIOS DE PROLIFERAÇçO CELULAR. A presente invenção refere-se a compostos e méto- 5 dos para o tratamento de distúrbios de proliferação celular.
BRPI0519424A 2004-12-28 2005-12-28 compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana BRPI0519424B8 (pt)

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US63983404P 2004-12-28 2004-12-28
US60/639.834 2004-12-28
US70455105P 2005-08-01 2005-08-01
US60/704.551 2005-08-01
US72734105P 2005-10-17 2005-10-17
US60/727.341 2005-10-17
PCT/US2005/047333 WO2006071960A2 (en) 2004-12-28 2005-12-28 Compositions and methods of treating cell proliferation disorders

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BRPI0519424B8 (pt) 2021-05-25
EP1836169A2 (en) 2007-09-26
HK1188985A1 (zh) 2014-05-23
DK1836169T3 (da) 2012-03-26
NL301145I2 (nl) 2021-12-07
NL301145I1 (pt) 2021-11-24
US8003641B2 (en) 2011-08-23
JP2008525530A (ja) 2008-07-17
CN101184734A (zh) 2008-05-21
US20070197783A1 (en) 2007-08-23
EP1836169B1 (en) 2012-02-08
FR21C1064I2 (fr) 2022-11-18
AU2005321966B2 (en) 2011-11-17
ATE544748T1 (de) 2012-02-15
HK1108695A1 (en) 2008-05-16
CA2594345C (en) 2013-11-05
US20110065705A1 (en) 2011-03-17
BE2021C001I2 (pt) 2025-02-11
KR101328273B1 (ko) 2013-11-14
LUC00235I2 (pt) 2024-07-01
BRPI0519424B1 (pt) 2021-01-05
WO2006071960A3 (en) 2007-05-24
HUS2100051I1 (hu) 2021-12-28
CY2022001I1 (el) 2022-03-24
US20060160800A1 (en) 2006-07-20
CA2594345A1 (en) 2006-07-06
KR101478933B1 (ko) 2015-01-02
CN101184734B (zh) 2013-05-29
FR21C1064I1 (fr) 2022-02-18
CY2022001I2 (el) 2023-01-27
US20240050438A1 (en) 2024-02-15
US20150182532A1 (en) 2015-07-02
EP1836169B9 (en) 2012-07-04
PL1836169T3 (pl) 2012-07-31
DK1836169T5 (da) 2023-10-09
JP2012082222A (ja) 2012-04-26
CN103274961B (zh) 2016-05-18
KR20130079661A (ko) 2013-07-10
KR20070099622A (ko) 2007-10-09
ES2382068T3 (es) 2012-06-05
CN103274961A (zh) 2013-09-04
US8980890B2 (en) 2015-03-17
JP5124285B2 (ja) 2013-01-23
US7300931B2 (en) 2007-11-27
WO2006071960A2 (en) 2006-07-06
AU2005321966A1 (en) 2006-07-06
US9655903B2 (en) 2017-05-23

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