BRPI0410185A - composição para manter a viabilidade de um orgão e célula - Google Patents
composição para manter a viabilidade de um orgão e célulaInfo
- Publication number
- BRPI0410185A BRPI0410185A BRPI0410185-5A BRPI0410185A BRPI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A
- Authority
- BR
- Brazil
- Prior art keywords
- viability
- organ
- maintain
- cell
- composition
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Dispersion Chemistry (AREA)
- Hospice & Palliative Care (AREA)
Abstract
"COMPOSIçãO PARA MANTER A VIABILIDADE DE UM óRGãO E CéLULA". A presente invenção está orientada a composições de nano partículas para manter a viabilidade de um órgão, tecido ou celular, quando os mesmos são separados a partir de suportes fisiológicos normais. As composições contêm composições de nano partículas e métodos de preservar os órgãos tais como rins, tanto in vivo como ex vivo, também são descritos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46920003P | 2003-05-09 | 2003-05-09 | |
PCT/US2004/014551 WO2004101758A2 (en) | 2003-05-09 | 2004-05-07 | Composition for maintaining organ and cell viability |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0410185A true BRPI0410185A (pt) | 2006-05-16 |
Family
ID=32991004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0410185-5A BRPI0410185A (pt) | 2003-05-09 | 2004-05-07 | composição para manter a viabilidade de um orgão e célula |
Country Status (12)
Country | Link |
---|---|
US (3) | US7220538B2 (pt) |
EP (3) | EP1475434A1 (pt) |
JP (2) | JP4870551B2 (pt) |
KR (1) | KR20060019525A (pt) |
CN (2) | CN1816617B (pt) |
AU (2) | AU2004236402B2 (pt) |
BR (1) | BRPI0410185A (pt) |
CA (2) | CA2526933C (pt) |
MX (1) | MXPA05012070A (pt) |
RU (1) | RU2005138320A (pt) |
WO (2) | WO2004099393A1 (pt) |
ZA (1) | ZA200509760B (pt) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1475434A1 (en) * | 2003-05-09 | 2004-11-10 | Oncoscience AG | Method for storing tumor cells |
US7087369B2 (en) * | 2003-12-17 | 2006-08-08 | The Regents Of The University Of California | Cornea preservation medium |
JP2005306749A (ja) * | 2004-04-19 | 2005-11-04 | Kringle Pharma Inc | Hgf含有臓器保存液 |
NZ702992A (en) | 2004-10-07 | 2016-06-24 | Transmedics Inc | Systems and methods for ex-vivo organ care |
US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
CA2632630C (en) | 2005-12-13 | 2016-12-06 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
KR100809046B1 (ko) * | 2006-03-10 | 2008-03-03 | 가톨릭대학교 산학협력단 | 풀루란을 가진 나노자가응집체 및 이의 이용방법 |
WO2008089103A2 (en) | 2007-01-12 | 2008-07-24 | University Of Maryland, Baltimore | Targeting ncca-atp channel for organ protection following ischemic episode |
EP2124539A2 (en) * | 2007-02-17 | 2009-12-02 | President and Fellows of Harvard College | Compositions and method for tissue preservation |
KR100834687B1 (ko) * | 2007-02-21 | 2008-06-02 | 주식회사 엘지생활건강 | 히노키티올 함유 지질 나노 입자 및 그의 제조방법 |
US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
KR100785656B1 (ko) * | 2007-05-14 | 2007-12-17 | 재단법인서울대학교산학협력재단 | 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체 |
US9770535B2 (en) | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
FR2919785B1 (fr) * | 2007-08-09 | 2017-10-20 | Hemarina Sa | Utilisation d'une globine, d'un protomere de globine ou d'une hemoglobine extracellulaire pour la preservation d'organes, de tissus, ou de cellules d'organes ou de tissus, ou de culture de cellules |
US9462802B2 (en) | 2008-01-31 | 2016-10-11 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
JP5690143B2 (ja) | 2008-02-13 | 2015-03-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 持続的細胞プログラミング装置 |
US11224218B2 (en) * | 2009-05-07 | 2022-01-18 | Hemarina | Heamoglobin and uses thereof |
US8389474B1 (en) * | 2009-07-14 | 2013-03-05 | Alan Anson Wanderer | Rationale for IL-1 β targeted therapy to improve harvested organ viability, allograft tolerance, replant success and for conditions characterized by reduced or absent arterial perfusion |
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JP5881422B2 (ja) * | 2010-01-29 | 2016-03-09 | 株式会社オーガンテクノロジーズ | 臓器又は組織の灌流培養方法及び灌流培養装置 |
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AU2012225497A1 (en) * | 2011-03-07 | 2013-10-24 | Massachusetts Institute Of Technology | Methods for transfecting cells with nucleic acids |
NZ616699A (en) | 2011-04-14 | 2016-03-31 | Transmedics Inc | Organ care solution for ex-vivo machine perfusion of donor lungs |
EP3417876B1 (en) | 2011-04-28 | 2021-03-31 | President and Fellows of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
AU2012261848B2 (en) | 2011-06-03 | 2017-06-15 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
SG11201402108YA (en) * | 2011-11-11 | 2014-06-27 | Essential Pharmaceuticals Llc | Kit comprising serum replacement and labile factors |
SI2838515T1 (sl) | 2012-04-16 | 2020-07-31 | President And Fellows Of Harvard College | Mezoporozni sestavki iz silicijevega dioksida za moduliranje imunskih odgovorov |
CN103461322B (zh) * | 2012-06-07 | 2016-08-03 | 西比曼生物科技(上海)有限公司 | 用于冻存复苏后的细胞的保存液 |
KR101426804B1 (ko) * | 2012-10-09 | 2014-08-05 | 김홍승 | 혈소판 보존 조성물, 이를 포함하는 혈소판 보존 키트 및 이를 이용한 혈소판 보존 방법 |
CN104918486B (zh) * | 2012-11-30 | 2017-12-15 | 法玛科思莫斯股份公司 | 冷冻保护试剂,冷冻保护和冷冻保存的组合物,其用途,和冷冻保存方法 |
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BR112016014611A8 (pt) | 2013-12-24 | 2023-05-09 | Univ Virginia Commonwealth | Usos de sulfatos de colesterol oxigenados (ocs) |
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CN110012901B (zh) * | 2019-04-12 | 2021-06-01 | 西北农林科技大学 | 一种用于猪精液常温保存的稀释制剂 |
KR102344674B1 (ko) * | 2019-06-19 | 2021-12-29 | 가천대학교 산학협력단 | 8-옥소-2'-디옥시구아노신을 유효성분으로 포함하는 이식용 장기의 보존 시 장기손상 방지용 조성물 |
WO2021090869A1 (ja) * | 2019-11-08 | 2021-05-14 | 株式会社バイオベルデ | 幹細胞用冷蔵保存液 |
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- 2003-09-30 EP EP03022146A patent/EP1475434A1/en not_active Withdrawn
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2004
- 2004-05-07 RU RU2005138320/15A patent/RU2005138320A/ru not_active Application Discontinuation
- 2004-05-07 AU AU2004236402A patent/AU2004236402B2/en not_active Ceased
- 2004-05-07 US US10/841,756 patent/US7220538B2/en not_active Expired - Lifetime
- 2004-05-07 EP EP04751778.4A patent/EP1624750B1/en not_active Expired - Lifetime
- 2004-05-07 WO PCT/EP2004/004897 patent/WO2004099393A1/en active Application Filing
- 2004-05-07 BR BRPI0410185-5A patent/BRPI0410185A/pt not_active IP Right Cessation
- 2004-05-07 US US10/556,083 patent/US7604933B2/en not_active Expired - Fee Related
- 2004-05-07 CA CA2526933A patent/CA2526933C/en not_active Expired - Fee Related
- 2004-05-07 CA CA2523417A patent/CA2523417C/en not_active Expired - Fee Related
- 2004-05-07 AU AU2004239310A patent/AU2004239310B2/en not_active Ceased
- 2004-05-07 WO PCT/US2004/014551 patent/WO2004101758A2/en active Application Filing
- 2004-05-07 CN CN2004800189342A patent/CN1816617B/zh not_active Expired - Fee Related
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- 2004-05-07 JP JP2006505398A patent/JP4870551B2/ja not_active Expired - Fee Related
- 2004-05-07 JP JP2006532912A patent/JP5192694B2/ja not_active Expired - Fee Related
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- 2004-05-07 CN CNA2004800125711A patent/CN1784142A/zh active Pending
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2005
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CA2526933A1 (en) | 2004-11-25 |
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CA2523417A1 (en) | 2004-11-18 |
JP5192694B2 (ja) | 2013-05-08 |
US7220538B2 (en) | 2007-05-22 |
JP2007524368A (ja) | 2007-08-30 |
EP1623021A1 (en) | 2006-02-08 |
JP2007502130A (ja) | 2007-02-08 |
EP1624750A2 (en) | 2006-02-15 |
US20070042338A1 (en) | 2007-02-22 |
RU2005138320A (ru) | 2006-04-27 |
WO2004101758A3 (en) | 2005-08-11 |
CN1816617B (zh) | 2010-12-01 |
AU2004236402B2 (en) | 2009-12-03 |
MXPA05012070A (es) | 2006-06-23 |
CA2526933C (en) | 2013-02-12 |
EP1624750A4 (en) | 2006-10-25 |
EP1624750B1 (en) | 2015-12-30 |
WO2004099393A1 (en) | 2004-11-18 |
JP4870551B2 (ja) | 2012-02-08 |
CN1816617A (zh) | 2006-08-09 |
WO2004101758A2 (en) | 2004-11-25 |
AU2004236402A1 (en) | 2004-11-18 |
KR20060019525A (ko) | 2006-03-03 |
US7604933B2 (en) | 2009-10-20 |
CA2523417C (en) | 2013-04-30 |
EP1475434A1 (en) | 2004-11-10 |
AU2004239310A1 (en) | 2004-11-25 |
AU2004239310B2 (en) | 2010-06-17 |
ZA200509760B (en) | 2006-11-29 |
CN1784142A (zh) | 2006-06-07 |
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