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BRPI0410185A - composição para manter a viabilidade de um orgão e célula - Google Patents

composição para manter a viabilidade de um orgão e célula

Info

Publication number
BRPI0410185A
BRPI0410185A BRPI0410185-5A BRPI0410185A BRPI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A
Authority
BR
Brazil
Prior art keywords
viability
organ
maintain
cell
composition
Prior art date
Application number
BRPI0410185-5A
Other languages
English (en)
Inventor
Joseph Fischer
Jan Baker
Robert G L Shorr
Original Assignee
Lifeblood Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32991004&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0410185(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lifeblood Medical Inc filed Critical Lifeblood Medical Inc
Publication of BRPI0410185A publication Critical patent/BRPI0410185A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026Blood substitute; Oxygen transporting formulations; Plasma extender
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

"COMPOSIçãO PARA MANTER A VIABILIDADE DE UM óRGãO E CéLULA". A presente invenção está orientada a composições de nano partículas para manter a viabilidade de um órgão, tecido ou celular, quando os mesmos são separados a partir de suportes fisiológicos normais. As composições contêm composições de nano partículas e métodos de preservar os órgãos tais como rins, tanto in vivo como ex vivo, também são descritos.
BRPI0410185-5A 2003-05-09 2004-05-07 composição para manter a viabilidade de um orgão e célula BRPI0410185A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46920003P 2003-05-09 2003-05-09
PCT/US2004/014551 WO2004101758A2 (en) 2003-05-09 2004-05-07 Composition for maintaining organ and cell viability

Publications (1)

Publication Number Publication Date
BRPI0410185A true BRPI0410185A (pt) 2006-05-16

Family

ID=32991004

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410185-5A BRPI0410185A (pt) 2003-05-09 2004-05-07 composição para manter a viabilidade de um orgão e célula

Country Status (12)

Country Link
US (3) US7220538B2 (pt)
EP (3) EP1475434A1 (pt)
JP (2) JP4870551B2 (pt)
KR (1) KR20060019525A (pt)
CN (2) CN1816617B (pt)
AU (2) AU2004236402B2 (pt)
BR (1) BRPI0410185A (pt)
CA (2) CA2526933C (pt)
MX (1) MXPA05012070A (pt)
RU (1) RU2005138320A (pt)
WO (2) WO2004099393A1 (pt)
ZA (1) ZA200509760B (pt)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1475434A1 (en) * 2003-05-09 2004-11-10 Oncoscience AG Method for storing tumor cells
US7087369B2 (en) * 2003-12-17 2006-08-08 The Regents Of The University Of California Cornea preservation medium
JP2005306749A (ja) * 2004-04-19 2005-11-04 Kringle Pharma Inc Hgf含有臓器保存液
NZ702992A (en) 2004-10-07 2016-06-24 Transmedics Inc Systems and methods for ex-vivo organ care
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
CA2632630C (en) 2005-12-13 2016-12-06 President And Fellows Of Harvard College Scaffolds for cell transplantation
KR100809046B1 (ko) * 2006-03-10 2008-03-03 가톨릭대학교 산학협력단 풀루란을 가진 나노자가응집체 및 이의 이용방법
WO2008089103A2 (en) 2007-01-12 2008-07-24 University Of Maryland, Baltimore Targeting ncca-atp channel for organ protection following ischemic episode
EP2124539A2 (en) * 2007-02-17 2009-12-02 President and Fellows of Harvard College Compositions and method for tissue preservation
KR100834687B1 (ko) * 2007-02-21 2008-06-02 주식회사 엘지생활건강 히노키티올 함유 지질 나노 입자 및 그의 제조방법
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
US9770535B2 (en) 2007-06-21 2017-09-26 President And Fellows Of Harvard College Scaffolds for cell collection or elimination
FR2919785B1 (fr) * 2007-08-09 2017-10-20 Hemarina Sa Utilisation d'une globine, d'un protomere de globine ou d'une hemoglobine extracellulaire pour la preservation d'organes, de tissus, ou de cellules d'organes ou de tissus, ou de culture de cellules
US9462802B2 (en) 2008-01-31 2016-10-11 Transmedics, Inc. Systems and methods for ex vivo lung care
US9370558B2 (en) 2008-02-13 2016-06-21 President And Fellows Of Harvard College Controlled delivery of TLR agonists in structural polymeric devices
JP5690143B2 (ja) 2008-02-13 2015-03-25 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 持続的細胞プログラミング装置
US11224218B2 (en) * 2009-05-07 2022-01-18 Hemarina Heamoglobin and uses thereof
US8389474B1 (en) * 2009-07-14 2013-03-05 Alan Anson Wanderer Rationale for IL-1 β targeted therapy to improve harvested organ viability, allograft tolerance, replant success and for conditions characterized by reduced or absent arterial perfusion
AU2010278702C1 (en) 2009-07-31 2016-07-14 Forsyth Dental Infirmary For Children Programming of cells for tolerogenic therapies
JP5881422B2 (ja) * 2010-01-29 2016-03-09 株式会社オーガンテクノロジーズ 臓器又は組織の灌流培養方法及び灌流培養装置
CN103548811B (zh) * 2010-02-23 2016-02-24 泰尔茂株式会社 红血球浓厚液用添加剂以及医疗用容器
WO2012048165A2 (en) 2010-10-06 2012-04-12 President And Fellows Of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
AU2012225497A1 (en) * 2011-03-07 2013-10-24 Massachusetts Institute Of Technology Methods for transfecting cells with nucleic acids
NZ616699A (en) 2011-04-14 2016-03-31 Transmedics Inc Organ care solution for ex-vivo machine perfusion of donor lungs
EP3417876B1 (en) 2011-04-28 2021-03-31 President and Fellows of Harvard College Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
AU2012261848B2 (en) 2011-06-03 2017-06-15 President And Fellows Of Harvard College In situ antigen-generating cancer vaccine
SG11201402108YA (en) * 2011-11-11 2014-06-27 Essential Pharmaceuticals Llc Kit comprising serum replacement and labile factors
SI2838515T1 (sl) 2012-04-16 2020-07-31 President And Fellows Of Harvard College Mezoporozni sestavki iz silicijevega dioksida za moduliranje imunskih odgovorov
CN103461322B (zh) * 2012-06-07 2016-08-03 西比曼生物科技(上海)有限公司 用于冻存复苏后的细胞的保存液
KR101426804B1 (ko) * 2012-10-09 2014-08-05 김홍승 혈소판 보존 조성물, 이를 포함하는 혈소판 보존 키트 및 이를 이용한 혈소판 보존 방법
CN104918486B (zh) * 2012-11-30 2017-12-15 法玛科思莫斯股份公司 冷冻保护试剂,冷冻保护和冷冻保存的组合物,其用途,和冷冻保存方法
WO2015074139A1 (en) * 2013-11-21 2015-05-28 University Of British Columbia Polymer based transplant preservation solution
CA2934487A1 (en) * 2013-12-20 2015-06-25 Essential Pharmaceuticals, Llc Media for cell culture
BR112016014611A8 (pt) 2013-12-24 2023-05-09 Univ Virginia Commonwealth Usos de sulfatos de colesterol oxigenados (ocs)
CN103931607A (zh) * 2014-04-04 2014-07-23 湖南苗王生物科技有限公司 一种鲟鱼精子玻璃化冷冻方法
CN107073090A (zh) 2014-04-30 2017-08-18 哈佛学院董事会 结合的疫苗装置和杀死癌细胞的方法
DK3151663T3 (da) 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
KR101668743B1 (ko) * 2014-08-08 2016-10-25 (주)세포바이오 식물 유래 재조합 인간 혈청 알부민 및 식물성 펩타이드를 유효성분으로 함유하는 세포 보존용 조성물
AU2015361996B2 (en) 2014-12-12 2019-09-26 Transmedics, Inc. Apparatus and method for organ perfusion
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
CN114099793A (zh) 2015-04-10 2022-03-01 哈佛学院院长等 免疫细胞捕获装置及其制备和使用方法
US10711240B2 (en) * 2015-06-30 2020-07-14 Societe Des Produits Neslte S.A. Composition suitable for protecting microorganisms
EP3824731B1 (en) 2015-09-09 2025-02-19 Transmedics, Inc. Aortic cannula for ex vivo organ care system
CN105284786B (zh) * 2015-10-15 2017-12-05 广州赛莱拉干细胞科技股份有限公司 一种细胞保存液及其在保护巨核祖细胞活力中的应用
KR102211270B1 (ko) * 2016-01-14 2021-02-04 디퍼이 신테스 프로덕츠, 인코포레이티드 Hutc의 동결보존을 위한 조성물 및 방법
WO2017136837A1 (en) 2016-02-06 2017-08-10 President And Fellows Of Harvard College Recapitulating the hematopoietic niche to reconstitute immunity
CN108450459A (zh) * 2016-03-06 2018-08-28 李倩 一种人脂肪干细胞用的细胞冻存液
EP3462861B9 (en) 2016-05-30 2023-12-20 Transmedics, Inc. Method for ex vivo lung ventilation with a varying exterior pressure
CN115404196A (zh) 2016-07-13 2022-11-29 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
AU2017305345B2 (en) 2016-08-02 2024-09-05 President And Fellows Of Harvard College Biomaterials for modulating immune responses
CN106613148A (zh) * 2016-11-19 2017-05-10 蚌埠市涂山村富民石榴专业合作社 一种大棚蒜黄多次采收的种植方法
CN106689115A (zh) * 2016-11-30 2017-05-24 广州赛莱拉干细胞科技股份有限公司 一种脐带保存液及其应用
CN106434532A (zh) * 2016-12-22 2017-02-22 叶宗耀 一种培养肝细胞的培养基及其制备方法
CN106857501B (zh) * 2017-02-22 2021-09-24 单纯 用于保存大鼠肝匀浆s9的储存液及其制备方法
CN107041362B (zh) * 2017-05-23 2020-12-22 天晴干细胞股份有限公司 一种肿瘤组织块深低温冷冻方法
CN107624753A (zh) * 2017-09-19 2018-01-26 北京瑞格瑞特生物科技有限公司 一种细胞低氧稳压运输方法
AU2019210204B2 (en) 2018-01-18 2024-05-16 EndoProtech, Inc. Treating microvascular dysfunction
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
CA3129732A1 (en) * 2019-02-14 2020-08-20 North Grove Investments, Inc. Compositions for maintaining the viability of living and static biological material, methods of making and the uses thereof
CN110012901B (zh) * 2019-04-12 2021-06-01 西北农林科技大学 一种用于猪精液常温保存的稀释制剂
KR102344674B1 (ko) * 2019-06-19 2021-12-29 가천대학교 산학협력단 8-옥소-2'-디옥시구아노신을 유효성분으로 포함하는 이식용 장기의 보존 시 장기손상 방지용 조성물
WO2021090869A1 (ja) * 2019-11-08 2021-05-14 株式会社バイオベルデ 幹細胞用冷蔵保存液
WO2021173535A1 (en) 2020-02-26 2021-09-02 Finless Foods Inc. Systems and methods for live fish tissue preservation
CN112514892B (zh) * 2020-12-25 2022-06-14 广州赛莱拉干细胞科技股份有限公司 一种外泌体冻存保护液及其制备方法
WO2023023309A1 (en) 2021-08-20 2023-02-23 Finless Foods Inc. Systems and methods for fish tissue preservation
CN113973808A (zh) * 2021-11-15 2022-01-28 深圳市人民医院 一种改进的细胞冻存液配方
CN114600872A (zh) 2022-04-13 2022-06-10 西安北光医学生物技术有限公司 一种细胞、组织或器官的抗损伤保存的方法及保存系统
CN114698630B (zh) * 2022-06-06 2022-08-23 天津百恩生物科技有限公司 一种胎盘组织保存液及其制备方法与应用
CN115349514B (zh) * 2022-07-08 2024-02-27 杭州联川生物技术股份有限公司 一种新鲜组织冻存液及其制备方法和应用

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1A (en) * 1836-07-13 John Ruggles Locomotive steam-engine for rail and other roads
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
JPS57194787A (en) * 1981-05-28 1982-11-30 Ajinomoto Co Inc Culture medium for animal cell
JPS5863385A (ja) * 1981-10-02 1983-04-15 ハナ・バイオロジツクス・インコ−ポレ−テツド 免疫系由来の細胞用培地
US4657866A (en) * 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4663166A (en) 1984-06-22 1987-05-05 Veech Richard L Electrolyte solutions and in vivo use thereof
US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
US4879283A (en) * 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
DE3871206D1 (de) * 1987-03-24 1992-06-25 Grace W R & Co Basisnaehrmedium fuer eine zellkultur.
WO1989001027A1 (en) * 1987-07-24 1989-02-09 Cetus Corporation Lipid microemulsions for culture media
US5061481A (en) 1989-03-20 1991-10-29 Kobayashi Kose Co., Ltd. Cosmetic composition having acryl-silicone graft copolymer
CA2018228C (en) * 1989-06-05 1996-02-27 Nancy L. Parenteau Cell culture systems and media
JPH03180176A (ja) * 1989-11-16 1991-08-06 W R Grace & Co 細胞培養のための基礎栄養培地
US5066578A (en) * 1989-12-21 1991-11-19 The Regents Of The University Of California Long-term preservation of organs for transplantation
US5104787A (en) * 1990-03-05 1992-04-14 Lindstrom Richard L Method for apparatus for a defined serumfree medical solution useful for corneal preservation
JPH0728732B2 (ja) * 1990-04-17 1995-04-05 日本石油株式会社 動物細胞増殖促進剤及び無血清培地
JPH0459735A (ja) * 1990-06-27 1992-02-26 Terumo Corp ヘモグロビン含有リポソーム
JP2956998B2 (ja) * 1990-10-11 1999-10-04 テルモ株式会社 移植器官潅流保存液および移植器官潅流保存法
ATE195338T1 (de) * 1991-06-17 2000-08-15 Life Technologies Inc Technik zur konzentration von kulturmedien
WO1993009220A1 (en) 1991-11-06 1993-05-13 Correa Paulo N Cell culture medium
US6291424B1 (en) * 1991-11-14 2001-09-18 Brigham And Women's Hospital Nitrosated and nitrosylated heme proteins
US5221668A (en) * 1992-02-26 1993-06-22 Abbott Laboratories Nutritional product for trauma and surgery patients
WO1993018751A1 (en) 1992-03-23 1993-09-30 Georgetown University Liposome encapsulated taxol and a method of using the same
US5370989A (en) 1992-04-03 1994-12-06 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5637315A (en) * 1993-01-04 1997-06-10 Thomas Jefferson University Treatment of disease states induced by oxidative stress
US5599659A (en) * 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
AU6523194A (en) 1993-03-26 1994-10-24 Biorelease Technologies, Inc. Compositions including heme-containing proteins and methods relating thereto
US5405772A (en) * 1993-06-18 1995-04-11 Amgen Inc. Medium for long-term proliferation and development of cells
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
AU7560994A (en) 1993-08-12 1995-03-14 University Of North Carolina At Chapel Hill, The Rinse solution for organs and tissues
FR2709666B1 (fr) * 1993-09-07 1995-10-13 Oreal Composition cosmétique ou dermatologique constituée d'une émulsion huile dans eau à base de globules huileux pourvus d'un enrobage cristal liquide lamellaire.
US5428039A (en) 1994-02-20 1995-06-27 The Center For Innovative Technology Method for electively achieving reversible hyperpolarized cardiac arrest
US5543316A (en) * 1994-04-20 1996-08-06 Diacrin, Inc. Injectable culture medium for maintaining viability of myoblast cells
CN1200036A (zh) 1995-09-14 1998-11-25 Lxr生物技术有限公司 含有磷脂混合物并具有抗细胞程序死亡活性的组合物
US5670545A (en) 1996-02-09 1997-09-23 Board Of Regents Of The University Of Colorado Method for the treatment of ischemic disease and reperfusion injury and the prevention of the adverse effects of reactive oxygen species
US5897987A (en) * 1996-03-25 1999-04-27 Advanced Reproduction Technologies, Inc. Use of arabinogalactan in cell cryopreservation media
US5696152A (en) 1996-05-07 1997-12-09 Wisconsin Alumni Research Foundation Taxol composition for use as organ preservation and cardioplegic agents
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
CA2266744A1 (en) 1996-09-27 1998-04-02 The Board Of Trustees Of The University Of Illinois Oxygen-binding heme proteins incorporating circularly-permuted globins
US6274305B1 (en) * 1996-12-19 2001-08-14 Tufts University Inhibiting proliferation of cancer cells
US6495532B1 (en) 1997-03-19 2002-12-17 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
WO1998041213A1 (en) * 1997-03-19 1998-09-24 Lxr Biotechnology Inc. Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
US6416740B1 (en) * 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
US5948609A (en) 1997-12-03 1999-09-07 Carter; Daniel C. Oxygen-transporting albumin-based blood replacement composition and blood volume expander
EP1064353B1 (en) * 1998-03-18 2002-11-06 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
ATE372377T1 (de) * 1998-03-30 2007-09-15 Mibelle Ag Cosmetics Verwendung von nanoemulsionen zur bestimmung der biokompatibilität von lipophilen stoffen im zellkultur-test und dafür geeignete nanoemulsionen
JP4222658B2 (ja) * 1998-06-23 2009-02-12 テルモ株式会社 細胞支持基材、培養装置および液体処理装置
US6406909B1 (en) * 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
US6204375B1 (en) * 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US6200590B1 (en) * 1998-08-10 2001-03-13 Naphcare, Inc. Controlled, phased-release suppository and its method of production
US6153582A (en) * 1998-11-05 2000-11-28 Bausch & Lomb Surgical, Inc. Defined serumfree medical solution for ophthalmology
US6582953B2 (en) * 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
FR2793495B1 (fr) * 1999-05-14 2001-08-10 Imv Technologies Dilueur pour la cryoconservation de spermatozoides de bovins
US6670184B2 (en) * 2000-06-23 2003-12-30 Basf Ag Method for producing a lipid emulsion for use in insect cell culture
ATE442041T1 (de) * 2000-07-28 2009-09-15 Murphy Christopher J Medium für transplantat
US7198895B2 (en) * 2000-11-14 2007-04-03 Mohanlal Ramon W In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals
CN1325046C (zh) * 2001-08-31 2007-07-11 麦吉尔大学 可生物降解的多聚纳米微囊及其应用
EP1475434A1 (en) 2003-05-09 2004-11-10 Oncoscience AG Method for storing tumor cells

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