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BR9814276A - Antìgenos de superfìcie - Google Patents

Antìgenos de superfìcie

Info

Publication number
BR9814276A
BR9814276A BR9814276-3A BR9814276A BR9814276A BR 9814276 A BR9814276 A BR 9814276A BR 9814276 A BR9814276 A BR 9814276A BR 9814276 A BR9814276 A BR 9814276A
Authority
BR
Brazil
Prior art keywords
surface antigens
well
nucleic acid
polypeptide
meningitidis
Prior art date
Application number
BR9814276-3A
Other languages
English (en)
Inventor
Ian Richard Anselm Peak
Michael Paul Jennings
Richard E Moxon
Original Assignee
Univ Queensland
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10823587&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9814276(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Queensland, Isis Innovation filed Critical Univ Queensland
Publication of BR9814276A publication Critical patent/BR9814276A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"ANTìGENOS DE SUPERFìCIE"<D>. A invenção provê um novo polipeptídio de superfície de Neisseria meningitidis bem como ácido nucléico e homólogos de seq³ência de ácido nucléico que codificam esta proteína. As composições farmacêuticas que contêm o polipeptídio e os ácido nucléicos da invenção são também descritas bem como métodos úteis no tratamento, prevenção e diagnóstico de infecção por N. meningitidis.
BR9814276-3A 1997-12-12 1998-12-14 Antìgenos de superfìcie BR9814276A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726398.2A GB9726398D0 (en) 1997-12-12 1997-12-12 Polypeptide and coding sequences
PCT/AU1998/001031 WO1999031132A1 (en) 1997-12-12 1998-12-14 NOVEL SURFACE PROTEIN OF $i(NEISSERIA MENINGITIDIS)

Publications (1)

Publication Number Publication Date
BR9814276A true BR9814276A (pt) 2000-10-03

Family

ID=10823587

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814276-3A BR9814276A (pt) 1997-12-12 1998-12-14 Antìgenos de superfìcie

Country Status (17)

Country Link
US (8) US6197312B1 (pt)
EP (2) EP1045859A4 (pt)
JP (2) JP4356961B2 (pt)
KR (1) KR100571533B1 (pt)
CN (2) CN101684148A (pt)
AU (1) AU747742B2 (pt)
BR (1) BR9814276A (pt)
CA (1) CA2314319C (pt)
CZ (1) CZ299646B6 (pt)
GB (1) GB9726398D0 (pt)
HU (1) HUP0100094A3 (pt)
IL (2) IL136684A0 (pt)
NO (1) NO20002990L (pt)
NZ (1) NZ505374A (pt)
PL (1) PL205984B1 (pt)
TR (1) TR200001709T2 (pt)
WO (1) WO1999031132A1 (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
CA2317815A1 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
FR2776928B1 (fr) * 1998-04-03 2000-06-23 Merial Sas Vaccins adn adjuves
PT1093517E (pt) 1998-05-01 2008-06-12 Novartis Vaccines & Diagnostic Antigénios e composições da neisseria msningitidis
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
AU2004240199B2 (en) * 1999-04-30 2007-05-17 Novartis Vaccines And Diagnostics S.R.L. Conserved Neisserial antigens
NZ530640A (en) * 1999-04-30 2006-06-30 Chiron S Conserved neisserial antigens
EP1173578A2 (en) * 1999-05-04 2002-01-23 Monsanto Company Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
WO2000071725A2 (en) * 1999-05-19 2000-11-30 Chiron S.P.A. Combination neisserial compositions
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
ES2539951T3 (es) * 1999-10-29 2015-07-07 Novartis Vaccines And Diagnositics S.R.L. Péptidos antigénicos de Neisseria
JP4840956B2 (ja) 1999-11-29 2011-12-21 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル ８５ｋＤａのナイセリア抗原
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
EP2281570A3 (en) 2000-01-17 2012-05-09 Novartis Vaccines and Diagnostics S.r.l. Outer membrane vesicle (OMV) vaccine comprising n. meningitidis serogroup B outer membrane proteins
CA2398139A1 (en) * 2000-01-25 2001-08-02 The University Of Queensland Proteins comprising conserved regions of neisseria meningitidis surface antigen nhha
AU2005202972B2 (en) * 2000-01-25 2008-04-24 The University Of Queensland Proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA
PT2270030E (pt) 2000-02-28 2012-07-24 Novartis Vaccines & Diagnostic Expressão heteróloga de proteínas de neisseria
NO20002828D0 (no) * 2000-06-02 2000-06-02 Statens Inst For Folkehelse Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
ES2615362T3 (es) 2001-07-27 2017-06-06 Glaxosmithkline Biologicals Sa Adhesinas de meningococos
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
GB0129007D0 (en) * 2001-12-04 2002-01-23 Chiron Spa Adjuvanted antigenic meningococcal compositions
BR0313100A (pt) * 2002-08-02 2005-06-21 Glaxosmithkline Biolog Sa Composição imunogênica, composição imunogênica isolada, vacina, método de tratamento ou prevenção de doença bacteriana gram-negativa, uso da vacina, cepa bacteriana gram-negativa geneticamente manipulada, método para preparar a composição imunogênica, método para preparar a vacina, método de preparar uma imunoglobulina para uso na prevenção ou tratamento de infecção neisserial, preparação de imunoglobulina, preparação farmacêutica, e, uso da preparação farmacêutica
EP1524990A2 (en) * 2002-08-02 2005-04-27 GlaxoSmithKline Biologicals S.A. Vaccine composition comprising lipooligosaccharide with reduced phase variability
CA2501812C (en) 2002-10-11 2012-07-10 Mariagrazia Pizza Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
TWI332843B (en) 2002-11-01 2010-11-11 Glaxosmithkline Biolog Sa Immunogenic composition
SI1961426T1 (sl) 2003-10-02 2011-10-28 Novartis Ag Kombinirana cepiva proti meningitisu
EP1667712B1 (en) 2003-10-02 2010-07-21 GlaxoSmithKline Biologicals S.A. B. pertussis antigens and use thereof in vaccination
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
TW200800235A (en) * 2005-10-18 2008-01-01 Otsuka Pharma Co Ltd Carrier composition for nucleic acid transport
ES2337309T5 (es) 2006-06-12 2013-07-30 Glaxosmithkline Biologicals S.A. Vacuna
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
US20090155873A1 (en) 2007-10-04 2009-06-18 Bio Architecture Lab, Inc. Biofuel production
MX2010005438A (es) * 2007-11-19 2010-06-01 Procter & Gamble Aparato para activar una trama.
WO2009097346A2 (en) * 2008-01-28 2009-08-06 Bio Architecture Lab, Inc. Isolated alcohol dehydrogenase enzymes and uses thereof
MX2010012999A (es) 2008-05-30 2012-03-07 U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army Vacuna de vesícula de membrana externa nativa multivalente del meningococo, método para su fabricación y uso.
WO2011110634A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
JP2013522177A (ja) 2010-03-11 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム グラム陰性細菌性、例えば髄膜炎菌性の感染または疾患に対する免疫原性組成物またはワクチン
GB201015132D0 (en) * 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
ES2759484T3 (es) 2010-09-10 2020-05-11 Glaxosmithkline Biologicals Sa Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo
RU2644340C2 (ru) 2012-06-14 2018-02-08 Новартис Аг Вакцины для менингококка серогруппы х
CZ2013450A3 (cs) * 2013-06-12 2014-02-12 Rieter Cz S.R.O. Způsob a zařízení ke sledování lineárního útvaru

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4550081A (en) 1980-05-19 1985-10-29 The Board Of Trustees Of The Leland Stanford Jr. University Non-reverting salmonella
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4769240A (en) * 1980-09-15 1988-09-06 Bactex, Inc. Pili of neisseria and vaccine compositions containing same
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
RU2023448C1 (ru) 1987-07-30 1994-11-30 Сентро Насьональ Де Биопрепарадос Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
DE58901612D1 (de) 1988-03-24 1992-07-09 Zach Johann Druck- oder kraftmessvorrichtung.
DE69133334T2 (de) * 1990-08-23 2004-05-13 University Of North Carolina At Chapel Hill Transferrin bindende proteine aus neisseria-gonorrhoeae und neisseria-meningitidis
FR2682041B1 (fr) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
IL117483A (en) * 1995-03-17 2008-03-20 Bernard Brodeur MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
US5646259A (en) 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
ATE199572T1 (de) 1995-11-21 2001-03-15 Univ Yale Unimolekulare segmentamplifikation und bestimmung
CU22559A1 (es) 1996-01-17 1999-05-03 Ct Ingenieria Genetica Biotech Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
CA2317815A1 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds

Also Published As

Publication number Publication date
NZ505374A (en) 2002-03-01
JP4651703B2 (ja) 2011-03-16
US20050058660A1 (en) 2005-03-17
CZ20002172A3 (cs) 2000-11-15
JP2009045071A (ja) 2009-03-05
IL199175A (en) 2013-07-31
US20120123093A1 (en) 2012-05-17
US20130085262A1 (en) 2013-04-04
JP4356961B2 (ja) 2009-11-04
US6607729B2 (en) 2003-08-19
CA2314319A1 (en) 1999-06-24
US6197312B1 (en) 2001-03-06
AU1649599A (en) 1999-07-05
JP2002508394A (ja) 2002-03-19
KR20010033074A (ko) 2001-04-25
NO20002990D0 (no) 2000-06-09
PL205984B1 (pl) 2010-06-30
HUP0100094A3 (en) 2003-08-28
TR200001709T2 (tr) 2001-03-21
GB9726398D0 (en) 1998-02-11
EP2354230A1 (en) 2011-08-10
HUP0100094A1 (hu) 2001-05-28
CZ299646B6 (cs) 2008-10-01
WO1999031132A1 (en) 1999-06-24
US6495345B1 (en) 2002-12-17
US20100331537A1 (en) 2010-12-30
CA2314319C (en) 2013-08-13
US20090270591A1 (en) 2009-10-29
CN1284965A (zh) 2001-02-21
KR100571533B1 (ko) 2006-04-14
CN101684148A (zh) 2010-03-31
IL136684A0 (en) 2001-06-14
US8067004B2 (en) 2011-11-29
AU747742B2 (en) 2002-05-23
PL341160A1 (en) 2001-03-26
US20020102276A1 (en) 2002-08-01
EP1045859A4 (en) 2001-08-22
NO20002990L (no) 2000-08-08
EP1045859A1 (en) 2000-10-25
US8034358B2 (en) 2011-10-11

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