BR9809368A - Composições sólidas adequadas para administração oral compreendendo l-carnitina ou fumarato de magnésio de alcanoil-l-carnitina. - Google Patents
Composições sólidas adequadas para administração oral compreendendo l-carnitina ou fumarato de magnésio de alcanoil-l-carnitina.Info
- Publication number
- BR9809368A BR9809368A BR9809368-1A BR9809368A BR9809368A BR 9809368 A BR9809368 A BR 9809368A BR 9809368 A BR9809368 A BR 9809368A BR 9809368 A BR9809368 A BR 9809368A
- Authority
- BR
- Brazil
- Prior art keywords
- carnitine
- magnesium
- solid compositions
- alkanoyl
- fumarate
- Prior art date
Links
- 239000008247 solid mixture Substances 0.000 title abstract 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052749 magnesium Inorganic materials 0.000 title abstract 2
- 239000011777 magnesium Substances 0.000 title abstract 2
- 229960004203 carnitine Drugs 0.000 title 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 2
- 235000015872 dietary supplement Nutrition 0.000 abstract 2
- 230000000378 dietary effect Effects 0.000 abstract 1
- QUIOHQITLKCGNW-TYYBGVCCSA-L magnesium;(e)-but-2-enedioate Chemical compound [Mg+2].[O-]C(=O)\C=C\C([O-])=O QUIOHQITLKCGNW-TYYBGVCCSA-L 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Animal Husbandry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
Patente de Invenção: <B>''COMPOSIçõES SóLIDAS ADEQUADAS PARA ADMINISTRAçãO ORAL COMPREENDENDO L-CARNITINA OU FUMARATO DE MAGNéSIO DE ALCANOIL-L-CARNITINA''<D>. Sais estáveis e não-higroscópicos consistindo em L-carnitina ou fumarato de magnésio de alcanoil-L-carnitina são descritos, os quais são adequados para preparar composições sólidas úteis como suplementos de dieta/nutricionais para uso humano e como suplemento para forragem para propósitos veterinários.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000254A IT1290600B1 (it) | 1997-04-30 | 1997-04-30 | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio fumarato |
PCT/IT1998/000079 WO1998049134A1 (en) | 1997-04-30 | 1998-04-08 | Solid compositions suitable for oral administration comprising l-carnitine or alkanoyl-l-carnitine magnesium fumarate |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9809368A true BR9809368A (pt) | 2000-07-04 |
Family
ID=11405029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9809368-1A BR9809368A (pt) | 1997-04-30 | 1998-04-08 | Composições sólidas adequadas para administração oral compreendendo l-carnitina ou fumarato de magnésio de alcanoil-l-carnitina. |
Country Status (22)
Country | Link |
---|---|
US (1) | US6051608A (pt) |
EP (1) | EP0979224B1 (pt) |
JP (1) | JP2001524106A (pt) |
KR (1) | KR100556238B1 (pt) |
CN (1) | CN1137088C (pt) |
AT (1) | ATE220659T1 (pt) |
AU (1) | AU733008B2 (pt) |
BR (1) | BR9809368A (pt) |
CA (1) | CA2288287C (pt) |
CZ (1) | CZ290159B6 (pt) |
DE (1) | DE69806590T2 (pt) |
DK (1) | DK0979224T3 (pt) |
ES (1) | ES2179485T3 (pt) |
HK (1) | HK1025559A1 (pt) |
HU (1) | HUP0002198A3 (pt) |
IL (2) | IL132275A0 (pt) |
IT (1) | IT1290600B1 (pt) |
NZ (1) | NZ500536A (pt) |
PL (1) | PL189602B1 (pt) |
PT (1) | PT979224E (pt) |
SK (1) | SK283818B6 (pt) |
WO (1) | WO1998049134A1 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2352485A1 (en) * | 1998-11-26 | 2000-06-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia |
IT1305308B1 (it) * | 1999-03-26 | 2001-05-04 | Biosint S P A | Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione |
US6429230B1 (en) * | 2000-01-19 | 2002-08-06 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
US6335369B1 (en) * | 2000-01-19 | 2002-01-01 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
US6914076B2 (en) * | 2000-01-19 | 2005-07-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
KR20010084849A (ko) * | 2000-02-29 | 2001-09-06 | 손 경 식 | L-카르니틴을 이용한 기능성 우유 및 그 제조 방법 |
ATE295690T1 (de) * | 2000-08-29 | 2005-06-15 | Lonza Ag | Verfahren zur herstellung einer granulierbaren mischung und carnitin-magnesium-hydroxycitrat |
DE10133200A1 (de) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Carnitin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
ITRM20010695A1 (it) * | 2001-11-26 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Uso della propionil l-carnitina o di un suo sale farmacologicamente accettabile per la preparazione di un medicamento per il trattamento del |
US20030235646A1 (en) * | 2002-03-15 | 2003-12-25 | Lonza Inc. | Method for improving quality of meat by supplementing pig diets and concentrates used therefor |
JP4539096B2 (ja) * | 2004-01-16 | 2010-09-08 | 日油株式会社 | 油性成分被覆l−カルニチン塩粉末およびその用途 |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
JP2006111550A (ja) * | 2004-10-13 | 2006-04-27 | Nisshin Pharma Inc | カルニチン含有製品 |
CN100518537C (zh) * | 2006-01-13 | 2009-07-29 | 天津天隆农业科技有限公司 | 一种含有二十八烷醇和l-肉碱的水产饲料及其生产方法 |
CN101209975B (zh) * | 2006-12-29 | 2010-12-01 | 沈阳科硕营养科技有限公司 | 左旋肉碱富马酸钙及其制备方法与用途 |
WO2025037993A1 (en) | 2023-08-13 | 2025-02-20 | Filip Majewski | Dosage form for peptide agents |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1153640A (en) * | 1967-04-10 | 1969-05-29 | Soc D Etudes Prod Chimique | A Carnitin Salt |
FR2529545B1 (fr) * | 1982-07-02 | 1985-05-31 | Sanofi Sa | Nouveaux sels de carnitine ainsi que leur procede de preparation |
DE3463261D1 (en) * | 1983-12-28 | 1987-05-27 | Sigma Tau Ind Farmaceuti | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
CA2018137C (en) * | 1989-06-14 | 2000-01-11 | Thomas Scholl | L-carnitine magnesium citrate |
US5073376A (en) * | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
IT1261688B (it) * | 1993-05-28 | 1996-05-29 | Avantgarde Spa | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
-
1997
- 1997-04-30 IT IT97RM000254A patent/IT1290600B1/it active IP Right Grant
-
1998
- 1998-04-08 CN CNB988046199A patent/CN1137088C/zh not_active Expired - Fee Related
- 1998-04-08 CA CA002288287A patent/CA2288287C/en not_active Expired - Fee Related
- 1998-04-08 CZ CZ19993813A patent/CZ290159B6/cs not_active IP Right Cessation
- 1998-04-08 EP EP98917597A patent/EP0979224B1/en not_active Expired - Lifetime
- 1998-04-08 JP JP54679098A patent/JP2001524106A/ja not_active Ceased
- 1998-04-08 NZ NZ500536A patent/NZ500536A/en unknown
- 1998-04-08 IL IL13227598A patent/IL132275A0/xx active IP Right Grant
- 1998-04-08 BR BR9809368-1A patent/BR9809368A/pt active Search and Examination
- 1998-04-08 WO PCT/IT1998/000079 patent/WO1998049134A1/en active IP Right Grant
- 1998-04-08 KR KR1019997009928A patent/KR100556238B1/ko not_active IP Right Cessation
- 1998-04-08 PT PT98917597T patent/PT979224E/pt unknown
- 1998-04-08 AU AU70776/98A patent/AU733008B2/en not_active Ceased
- 1998-04-08 SK SK1462-99A patent/SK283818B6/sk not_active IP Right Cessation
- 1998-04-08 HU HU0002198A patent/HUP0002198A3/hu unknown
- 1998-04-08 PL PL98336530A patent/PL189602B1/pl not_active IP Right Cessation
- 1998-04-08 DK DK98917597T patent/DK0979224T3/da active
- 1998-04-08 ES ES98917597T patent/ES2179485T3/es not_active Expired - Lifetime
- 1998-04-08 AT AT98917597T patent/ATE220659T1/de not_active IP Right Cessation
- 1998-04-08 US US09/402,649 patent/US6051608A/en not_active Expired - Fee Related
- 1998-04-08 DE DE69806590T patent/DE69806590T2/de not_active Expired - Lifetime
-
1999
- 1999-10-07 IL IL132275A patent/IL132275A/en not_active IP Right Cessation
-
2000
- 2000-04-20 HK HK00102412A patent/HK1025559A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2179485T3 (es) | 2003-01-16 |
AU7077698A (en) | 1998-11-24 |
HUP0002198A2 (hu) | 2000-11-28 |
KR20010020320A (ko) | 2001-03-15 |
ATE220659T1 (de) | 2002-08-15 |
IT1290600B1 (it) | 1998-12-10 |
DE69806590D1 (de) | 2002-08-22 |
CZ290159B6 (cs) | 2002-06-12 |
SK146299A3 (en) | 2000-09-12 |
US6051608A (en) | 2000-04-18 |
HUP0002198A3 (en) | 2001-10-29 |
NZ500536A (en) | 2001-04-27 |
CN1253544A (zh) | 2000-05-17 |
HK1025559A1 (en) | 2000-11-17 |
ITRM970254A1 (it) | 1998-10-30 |
PL336530A1 (en) | 2000-07-03 |
JP2001524106A (ja) | 2001-11-27 |
CN1137088C (zh) | 2004-02-04 |
CZ381399A3 (cs) | 2000-02-16 |
IL132275A0 (en) | 2001-03-19 |
PT979224E (pt) | 2002-12-31 |
ITRM970254A0 (it) | 1997-04-30 |
AU733008B2 (en) | 2001-05-03 |
SK283818B6 (sk) | 2004-02-03 |
IL132275A (en) | 2006-08-01 |
WO1998049134A1 (en) | 1998-11-05 |
KR100556238B1 (ko) | 2006-03-03 |
CA2288287A1 (en) | 1998-11-05 |
PL189602B1 (pl) | 2005-08-31 |
CA2288287C (en) | 2008-06-10 |
DK0979224T3 (da) | 2002-09-02 |
DE69806590T2 (de) | 2003-01-30 |
EP0979224B1 (en) | 2002-07-17 |
EP0979224A1 (en) | 2000-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL.8: A61K 31/205, A61K 31/197, C07C 57/15, C07C 229/22, C07C 217/04, C07C 215/08, C07C 215/40, A23L 1/305, A23K 1/16, A61K 9/20, A61P 9/04, A61P 9/06, A61P 9/10, A61P 21/02, A61P 21/04 Ipc: A61K 31/205 (2008.04), A61K 31/197 (2008.04), C07C |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C07C 229/22 (2006.01), A23K 20/105 (2016.0 |