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BR112012017831A8 - micro-organismos produtores de ácido eicosapentaenoico, composições de ácido graxo e métodos de fabricação e uso dos mesmos - Google Patents

micro-organismos produtores de ácido eicosapentaenoico, composições de ácido graxo e métodos de fabricação e uso dos mesmos

Info

Publication number
BR112012017831A8
BR112012017831A8 BR112012017831A BR112012017831A BR112012017831A8 BR 112012017831 A8 BR112012017831 A8 BR 112012017831A8 BR 112012017831 A BR112012017831 A BR 112012017831A BR 112012017831 A BR112012017831 A BR 112012017831A BR 112012017831 A8 BR112012017831 A8 BR 112012017831A8
Authority
BR
Brazil
Prior art keywords
manufacture
methods
producing microorganisms
fatty acid
eicosapentaenoic acid
Prior art date
Application number
BR112012017831A
Other languages
English (en)
Other versions
BR112012017831A2 (pt
BR112012017831B1 (pt
BR112012017831B8 (pt
Inventor
Milton Hansen Jon
W Pfeifer Joseph Iii
E Apt Kirk
Warren Behrens Paul
Zirkle Ross
Lynn Stahl Tracey
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44277725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012017831(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Priority to BR122015020119A priority Critical patent/BR122015020119B8/pt
Publication of BR112012017831A2 publication Critical patent/BR112012017831A2/pt
Publication of BR112012017831A8 publication Critical patent/BR112012017831A8/pt
Publication of BR112012017831B1 publication Critical patent/BR112012017831B1/pt
Publication of BR112012017831B8 publication Critical patent/BR112012017831B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/68—Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/02—Refining fats or fatty oils by chemical reaction
    • C11B3/04—Refining fats or fatty oils by chemical reaction with acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • C12N1/105—Protozoal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/90—Protozoa ; Processes using protozoa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish
    • Y02A40/818—Alternative feeds for fish, e.g. in aquacultures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
BR112012017831A 2010-01-19 2010-03-22 óleo microbiano, alimento animal e biomassa compreendendo o referido óleo microbiano BR112012017831B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122015020119A BR122015020119B8 (pt) 2010-01-19 2010-03-22 óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29645610P 2010-01-19 2010-01-19
US61/296,456 2010-01-19
PCT/US2010/028175 WO2011090493A1 (en) 2010-01-19 2010-03-22 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

Publications (4)

Publication Number Publication Date
BR112012017831A2 BR112012017831A2 (pt) 2015-10-06
BR112012017831A8 true BR112012017831A8 (pt) 2018-06-26
BR112012017831B1 BR112012017831B1 (pt) 2021-03-09
BR112012017831B8 BR112012017831B8 (pt) 2021-05-25

Family

ID=44277725

Family Applications (2)

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BR112012017831A BR112012017831B8 (pt) 2010-01-19 2010-03-22 óleo microbiano, alimento animal e biomassa compreendendo o referido óleo microbiano
BR122015020119A BR122015020119B8 (pt) 2010-01-19 2010-03-22 óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada

Family Applications After (1)

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BR122015020119A BR122015020119B8 (pt) 2010-01-19 2010-03-22 óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada

Country Status (19)

Country Link
US (6) US9924733B2 (pt)
EP (3) EP4056708A1 (pt)
JP (4) JP5920890B2 (pt)
KR (4) KR102155409B1 (pt)
CN (2) CN102884201B (pt)
AR (1) AR077916A1 (pt)
AU (1) AU2010343305B2 (pt)
BR (2) BR112012017831B8 (pt)
CA (3) CA2993690C (pt)
CL (2) CL2012002013A1 (pt)
DK (1) DK2526197T3 (pt)
EA (1) EA031136B1 (pt)
HK (1) HK1221873A1 (pt)
MX (2) MX343403B (pt)
MY (1) MY160121A (pt)
NZ (2) NZ626633A (pt)
PH (2) PH12012501469A1 (pt)
TW (2) TWI649424B (pt)
WO (1) WO2011090493A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012521195A (ja) * 2009-03-19 2012-09-13 マーテック バイオサイエンシーズ コーポレーション 多価不飽和脂肪酸シンターゼの核酸分子およびポリペプチド、組成物、ならびにそれらの作製方法および使用
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US9924733B2 (en) 2010-01-19 2018-03-27 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
US10392578B2 (en) 2010-06-01 2019-08-27 Dsm Ip Assets B.V. Extraction of lipid from cells and products therefrom
EP3831952A1 (en) * 2011-07-21 2021-06-09 DSM IP Assets B.V. Methods of making eicosapentaenoic acid in microorganisms
EP2734626B1 (en) * 2011-07-21 2020-12-16 DSM IP Assets B.V. Microbial oils enriched in polyunsaturated fatty acids
EA035287B1 (ru) 2011-07-21 2020-05-25 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
TWI708836B (zh) 2013-12-20 2020-11-01 荷蘭商Ｄｓｍ智慧財產有限公司 用於從微生物細胞獲得微生物油之方法（二）
CN116254148A (zh) 2013-12-20 2023-06-13 帝斯曼知识产权资产管理有限公司 用于从微生物细胞获得微生物油的方法
TWI651408B (zh) 2013-12-20 2019-02-21 Ｄｓｍ智慧財產有限公司 用於從微生物細胞獲得微生物油之方法（一）
CA2934506C (en) 2013-12-20 2022-05-03 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
EP3083545B1 (en) 2013-12-20 2023-08-02 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
ES2984970T3 (es) 2013-12-20 2024-10-31 Mara Renewables Corp Métodos para recuperar aceite de microorganismos
BR112017006838B1 (pt) 2014-10-02 2021-07-06 Evonik Operations Gmbh Processo para produzir um alimento para animais compreendendo biomassa contendo pufa, alimento para animais e método para criar animais
BR112017006833B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo ácido graxo poli-insaturado e processo para produzir o mesmo
CA2958463C (en) 2014-10-02 2022-05-03 Evonik Industries Ag Method for raising animals
DK179981B1 (en) 2014-10-02 2019-11-29 Evonik Degussa Gmbh Process for producing a PUFA-containing feedstuff by extruding a PUFA-containing biomass
AU2015359335B2 (en) 2014-12-12 2019-11-14 Dsm Ip Assets B.V. Feed supplement material for use in aquaculture feed
US20180320208A1 (en) * 2015-07-03 2018-11-08 Kyushu University, National University Corporation Labyrinthulid microorganism capable of producing microbial oil, microbial oil, methods for producing said microorganism and for producing said microbial oil, and uses of said microorganism and said microbial oil
CN107529783A (zh) * 2015-10-01 2018-01-02 帝斯曼知识产权资产管理有限公司 用于宠物食品中的补充物质
KR102442450B1 (ko) * 2016-05-12 2022-09-14 디에스엠 아이피 어셋츠 비.브이. 미세조류에서 오메가-3 다중불포화 지방산 생산을 증가시키는 방법
RU2764558C2 (ru) * 2016-12-15 2022-01-18 Сосьете Де Продюи Нестле С.А. Композиции и способы, регулирующие усвояемость у животного-компаньона
DK3665296T3 (da) * 2017-08-10 2022-07-11 Dsm Ip Assets Bv Fremgangsmåde med dobbeltcentrifugering til oprensning af nærende olie
JP2023521632A (ja) 2020-04-03 2023-05-25 マラ リニューアブルズ コーポレーション 高レベルのオメガ－３脂肪酸を有する微生物性油
US20210401731A1 (en) * 2020-06-24 2021-12-30 Marco Ruggiero Anti-Aging Formula
SE2151489A1 (en) * 2021-12-07 2023-06-08 Mycorena Ab A food product or food ingredient comprising fungi biomass with an increased intracellular fat content
EP4466370A1 (en) * 2022-01-17 2024-11-27 Phycoil Biotechnology International, Inc. Novel thraustochytrid strain for the production of biomaterials including long-chain polyunsaturated fatty acids
EP4469588A1 (en) 2022-01-25 2024-12-04 DSM IP Assets B.V. Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production
WO2025101743A1 (en) * 2023-11-07 2025-05-15 Dsm Ip Assets B.V. Nutritional oils having reduced mosh content and methods of making the same

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485173A (en) 1981-01-19 1984-11-27 Cpc International Inc. Preparation of fats and oils
EP0252716B1 (en) 1986-07-08 1993-01-07 Suntory Limited Process for production of bishomo- gamma-linolenic acid and eicosapentaenoic acid
US5246841A (en) 1986-12-26 1993-09-21 Sagami Chemical Research Center Microbial process for production of eicosapentaenoic acid
AU602376B2 (en) 1986-12-26 1990-10-11 Sagami Chemical Research Center Process for production of eicosapentaenoic acid
JP2746371B2 (ja) 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
JP2710344B2 (ja) 1988-07-13 1998-02-10 サントリー株式会社 高度不飽和脂肪酸及びこれを含有する脂質の製造方法
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5698244A (en) 1988-09-07 1997-12-16 Omegatech Inc. Method for raising animals having high concentrations of omega-3 highly unsaturated fatty acids
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5340594A (en) 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5244921A (en) 1990-03-21 1993-09-14 Martek Corporation Eicosapentaenoic acids and methods for their production
CA2101274C (en) * 1991-01-24 1998-12-15 David J. Kyle Microbial oil mixtures and uses thereof
JPH078215A (ja) 1993-04-30 1995-01-13 Kawasaki Steel Corp ドコサヘキサエン酸含有海洋性微細藻類食品素材およびその製造方法
WO1996033263A1 (fr) * 1995-04-17 1996-10-24 JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes
GB9514649D0 (en) 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
JP2000508888A (ja) 1996-03-28 2000-07-18 ヒスト―ブロカデス・ベスローテン・フェンノートシャップ 低温殺菌したバイオマスからの微生物多不飽和脂肪酸含有オイルの調製
US20030143659A1 (en) 1996-03-28 2003-07-31 Hendrik Louis Bijl Process for the preparation of a granular microbial biomass and isolation of a compound thereform
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
AU723553C (en) * 1996-07-23 2005-04-14 Nagase & Co., Ltd. Process for preparing docosahexaenoic acid and docosapentaenoic acid
EP2308988A1 (en) 1996-12-27 2011-04-13 Suntory Holdings Limited Media for culturing microorganisms and process for producing unsaturated fatty acids or lipids containing the same
WO1999006585A1 (en) 1997-08-01 1999-02-11 Martek Biosciences Corporation Dha-containing nutritional compositions and methods for their production
DE69825173T2 (de) 1997-10-30 2005-08-25 Morishita Jintan Co. Ltd. Doppelschichtige kapsel von ungesättigten fettsäuren oder deren derivate und verfahren zu deren herstellung
JP4079494B2 (ja) * 1998-03-04 2008-04-23 サントリー株式会社 アラキドン酸及び／又はエイコサペンタエン酸含有油脂の製造方法
JP4175698B2 (ja) 1998-06-19 2008-11-05 サントリー株式会社 新規なトリグリセリド及びそれを含む組成物
US8003772B2 (en) * 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
JP4518674B2 (ja) 1999-03-04 2010-08-04 サントリーホールディングス株式会社 ドコサペンタエン酸含有物質の利用
AU7321300A (en) 1999-09-29 2001-04-30 Micro Gaia Co., Ltd. Method of culturing algae capable of producing phototrophic pigments, highly unsaturated fatty acids, or polysaccharides at high concentration
AU2001232786A1 (en) 2000-01-11 2001-07-24 Monsanto Company Process for making an enriched mixture of polyunsaturated fatty acid esters
ES2675517T3 (es) * 2000-01-19 2018-07-11 Dsm Ip Assets B.V. Proceso de extracción sin solvente
CN105567752A (zh) 2000-01-28 2016-05-11 Dsmip资产公司 通过在发酵罐中高密度培养真核微生物来增加含有多烯脂肪酸的脂质的产生
EP1261733A4 (en) 2000-02-24 2005-11-23 Thomas Veach Ii Long PROCESS FOR THE PREPARATION OF CAROTENOIDS, XANTHOPHYLLENE AND APO-CAROTENOIDES USING EUKARYOTIC MICROORGANISMS
WO2001073099A1 (en) 2000-03-29 2001-10-04 Council Of Scientific And Industrial Research A method for enhancing levels of polyunsaturated fatty acids in thraustochytrids
US6410282B1 (en) 2000-03-30 2002-06-25 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid fungi
JP3425622B2 (ja) 2000-03-30 2003-07-14 独立行政法人産業技術総合研究所 ラビリンチュラ属菌を用いた高度不飽和脂肪酸含有培養物および高度不飽和脂肪酸含有油脂の製造方法
EP1178118A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
ES2324640T3 (es) * 2001-03-09 2009-08-12 Societe Des Produits Nestle S.A. Aceite que contiene un o unos acido(s) graso(s) poliin-saturado(s) de cadena larga resultante de una biomasa, procedimiento de preparacion, alimento, composicion nutricional, cosmetica o farmaceutica que lo contiene.
TWI350854B (en) * 2001-04-16 2011-10-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
JP4995377B2 (ja) 2001-04-26 2012-08-08 花王株式会社 油脂組成物
JP2004536059A (ja) * 2001-05-14 2004-12-02 マーテック バイオサイエンシズ ボールダー コーポレーション 微生物、遺伝的に改変された植物種子および海洋生物由来のω−３および／またはω−６高度不飽和脂肪酸を含有する極性脂質の豊富な画分の生成および使用
JPWO2003004667A1 (ja) 2001-07-02 2004-10-28 サントリー株式会社 高度不飽和脂肪酸含有トリグリセリドを含む油脂の製造方法
US20030060509A1 (en) * 2001-08-24 2003-03-27 Elswyk Mary Van Products containing highly unsaturated fatty acids for use by women and their children during stages of preconception, pregnancy and lactation/post-partum
DE10151155A1 (de) 2001-10-19 2003-05-08 Nutrinova Gmbh Native PUFA-Triglyceridmischungen mit einem hohen Gehalt an mehrfach ungesättigten Fettsäuren sowie Verfahren zu deren Herstellung und deren Verwendung
US6677470B2 (en) 2001-11-20 2004-01-13 Natural Asa Functional acylglycerides
EP2261312A1 (en) * 2001-12-12 2010-12-15 Martek Biosciences Corporation Extraction and Winterization of Lipids from Oilseed and Microbial Sources
US20040203120A1 (en) 2002-03-22 2004-10-14 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
CA2484334C (en) 2002-05-03 2013-01-22 Martek Biosciences Corporation High-quality lipids and methods for producing by enzymatic liberation from biomass
CN101787379A (zh) 2002-06-19 2010-07-28 帝斯曼知识产权资产管理有限公司 包含多不饱和脂肪酸的微生物油的制备
ATE407190T1 (de) * 2002-09-04 2008-09-15 Nestec Sa Verfahren zur herstellung von einem öl, das langkettige, mehrfach ungesättigte fettsäuren aus biomassen enthält, lebensmittel, nahrungsmittelzusammensetzung, kosmetische oder pharmazeutische zusammensetzung, die dieses ölenthält
JP4522257B2 (ja) 2002-09-13 2010-08-11 サントリーホールディングス株式会社 エステル交換油脂またはトリグリセリドの製造方法
EP3336193A1 (en) 2002-10-11 2018-06-20 Nippon Suisan Kaisha, Ltd. Process for producing microbial fat or oil having lowered unsaponifiable matter content and said fat or oil
RU2235481C2 (ru) 2002-11-20 2004-09-10 Общество с ограниченной ответственностью "Гелла-Фарма" Способ получения биологически активной добавки к пище (варианты)
JP4280158B2 (ja) * 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
CA2519773C (en) 2003-03-27 2014-02-18 Kengo Akimoto Lipid-improving agent and composition containing lipid-improving agent
US20050019880A1 (en) 2003-03-31 2005-01-27 Council Of Scientific And Industrial Research Method of enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
US6846942B2 (en) 2003-05-20 2005-01-25 David Rubin Method for preparing pure EPA and pure DHA
CN1845986A (zh) 2003-09-01 2006-10-11 诺维信公司 用于增加来自海洋微生物的生物质和/或生物质成分的产率的方法
KR101761164B1 (ko) 2003-10-02 2017-07-25 디에스엠 아이피 어셋츠 비.브이. 변형량의 염소 및 칼륨을 사용하는 미세조류 중에 고농도 디에치에이의 생산
DE10352838A1 (de) 2003-11-10 2005-07-07 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Kultivierung von Mikroorganismen der Gattung Thraustochytriales unter Verwendung eines optimierten Niedrigsalzmediums
TWI365716B (en) 2003-12-02 2012-06-11 Suntory Holdings Ltd Oil or fat and oil compositions containing phospholipids and a long-chain polyunsaturated fatty acid supply compound, and food using same
SE0303513D0 (sv) 2003-12-19 2003-12-19 Pronova Biocare As Use of a fatty acid composition comprising at least one of epa and dha or any combinations thereof
CA2551659C (en) 2003-12-30 2015-02-17 Dsm Ip Assets B.V. Deaeration process
GB0403247D0 (en) 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
DE602005021503D1 (de) 2004-08-12 2010-07-08 Nippon Suisan Kaisha Ltd Verfahren zur herstellung mehrfach ungesättigter fettsäuren unter verwendung einer neuen zellkonservierungstechnik
SG155228A1 (en) * 2004-08-24 2009-09-30 Suntory Holdings Ltd Process for production of microbial fat/oil containing discretional amount of diacylglycerol and said fat/oil
JP4624040B2 (ja) 2004-09-06 2011-02-02 日本水産株式会社 菌体培養方法
TWI376204B (en) 2004-11-04 2012-11-11 Monsanto Technology Llc High pufa oil compositions
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
US8241868B2 (en) 2005-02-08 2012-08-14 Nippon Suisan Kaisha, Ltd. Production of polyunsaturated fatty acids using cell treatment method
US8163515B2 (en) * 2005-06-07 2012-04-24 Ocean Nutrition Canada Limited Eukaryotic Microorganisms for producing lipids and antioxidants
CN101252844A (zh) * 2005-07-01 2008-08-27 马泰克生物科学公司 包含多不饱和脂肪酸的油产品及其用途和制备方法
SG163551A1 (en) 2005-07-01 2010-08-30 Martek Biosciences Corp Polyunsaturated fatty acid-containing oil product and uses and production thereof
CN101272999B (zh) 2005-07-12 2013-01-23 阿德莱德研究和创新私人有限公司 微量营养素肥料用螯合剂
WO2007066232A2 (en) 2005-10-07 2007-06-14 Ocean Nutrition Canada Ltd. Salts of fatty acids and methods of making and using thereof
CA2639071A1 (en) 2005-12-16 2007-06-21 Avesthagen Limited Docosahexaenoic acid (dha) producing thraustochytrid strain - sc1
CA2632949C (en) 2005-12-21 2012-05-22 Brudy Technology, S.L. Use of dha, epa or dha-derived epa for treating a pathology associated with cellular oxidative damage
EP1976973B1 (en) 2005-12-29 2010-07-21 ABL Biotechnologies Ltd. Novel strain of schizochytrium limacinum useful in the production of lipids and extracellular polysaccharides and process thereof
KR20090007407A (ko) 2006-04-11 2009-01-16 마텍 바이오싸이언스스 코포레이션 장쇄 다중불포화 지방산을 포함하는 식품 제품 및 그의 제조 방법
EP2046136A2 (en) 2006-06-23 2009-04-15 The Procter and Gamble Company Concentrated and odorless omega 3 fatty acids
US8877465B2 (en) 2006-07-05 2014-11-04 Photonz Corporation Limited Production of ultrapure EPA and polar lipids from largely heterotrophic culture
WO2008012329A2 (en) 2006-07-28 2008-01-31 V. Mane Fils Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component
CN105154481A (zh) * 2006-08-01 2015-12-16 帝斯曼营养品股份公司 产油微生物及改良这些微生物的方法
SG174081A1 (en) * 2006-08-29 2011-09-29 Martek Biosciences Corp Use of dpa(n-6) oils in infant formula
CA2663807C (en) 2006-10-30 2018-05-01 E.I. Du Pont De Nemours And Company .delta.17 desaturase and its use in making polyunsaturated fatty acids
US8936923B2 (en) 2006-12-05 2015-01-20 Biomass Research & Refining Pty Ltd Production of biodiesel
JP5101894B2 (ja) 2007-01-15 2012-12-19 サントリーホールディングス株式会社 高度不飽和脂肪酸及びこれを含有する脂質の製造方法
US20080234377A1 (en) 2007-03-23 2008-09-25 Martek Biosciences Corporation Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions
EP1992233A1 (en) 2007-05-11 2008-11-19 DSMIP Assets B.V. Stabilized marine oils and process of making them
WO2009002145A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Lipid composition for improving function of brain functioning
US20090011012A1 (en) 2007-07-06 2009-01-08 Baum Seth J Fatty acid compositions and methods of use
JP2010538642A (ja) * 2007-09-12 2010-12-16 マーテック バイオサイエンシーズ コーポレーション 生物油ならびにその生産および使用
US20090099261A1 (en) 2007-09-25 2009-04-16 Isi Brands Inc. Omega-3 mixtures
CA2701094A1 (en) * 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
DE102008042932A1 (de) 2008-10-17 2010-04-22 Evonik Degussa Gmbh Herstellung und Verwendung von Methionylmethionin als Futtermitteladditiv für Fische und Krustentiere
EP3517622A1 (en) * 2008-11-28 2019-07-31 Corbion Biotech, Inc. Production of tailored oils in heterotrophic microorganisms
US20100178369A1 (en) 2009-01-15 2010-07-15 Nicole Lee Arledge Antioxidant-stabilized concentrated fish oil
CN102333880A (zh) 2009-02-25 2012-01-25 V.B.医疗私人有限公司 发酵生产二十二碳六烯酸的改进方法
BRPI1009431A2 (pt) 2009-03-09 2016-03-01 Pronova Biopharma Norge As pré-concentrados farmacêuticos e de suplemento alimentar, sistemas de liberação de droga, método de tratamento de pelo menos um problema de saúde em sujeito em necessidade do mesmo e método e sistema
BRPI0923968B1 (pt) 2009-03-19 2020-04-28 Dsm Ip Assets Bv composição, produto alimentício e alimento animal compreendendo óleo microbiano
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
JP2012521195A (ja) 2009-03-19 2012-09-13 マーテック バイオサイエンシーズ コーポレーション 多価不飽和脂肪酸シンターゼの核酸分子およびポリペプチド、組成物、ならびにそれらの作製方法および使用
US9717703B2 (en) 2009-10-16 2017-08-01 Glaxosmithkline Llc Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed
WO2011082190A1 (en) 2009-12-28 2011-07-07 Martek Biosciences Corporation Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof
CA2785867C (en) 2009-12-28 2018-03-27 Dsm Ip Assets B.V. Production of hemagglutinin-neuraminidase protein in microalgae
US9924733B2 (en) 2010-01-19 2018-03-27 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
US10392578B2 (en) 2010-06-01 2019-08-27 Dsm Ip Assets B.V. Extraction of lipid from cells and products therefrom
EP2734626B1 (en) * 2011-07-21 2020-12-16 DSM IP Assets B.V. Microbial oils enriched in polyunsaturated fatty acids
EA035287B1 (ru) 2011-07-21 2020-05-25 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения
EP3831952A1 (en) * 2011-07-21 2021-06-09 DSM IP Assets B.V. Methods of making eicosapentaenoic acid in microorganisms
EP3256555B1 (en) * 2015-02-09 2020-07-15 Archer Daniels Midland Company Renewable source-derived polymer oil macroinitiators and thermoplastic block copolymers derived therefrom

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CA2993690A1 (en) 2011-07-28
CA2896012C (en) 2017-08-01
JP2018078900A (ja) 2018-05-24
US20150313861A1 (en) 2015-11-05
EA201290656A1 (ru) 2013-02-28
BR112012017831A2 (pt) 2015-10-06
JP5920890B2 (ja) 2016-05-18
BR122015020119A2 (pt) 2015-12-29
US9668499B2 (en) 2017-06-06
MX2012008388A (es) 2012-08-15
US20150237888A1 (en) 2015-08-27
CA2896012A1 (en) 2011-07-28
AU2010343305A1 (en) 2012-09-06
US20170164639A1 (en) 2017-06-15
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CA2993690C (en) 2022-03-22
US9924733B2 (en) 2018-03-27
JP2016052311A (ja) 2016-04-14
KR20170104628A (ko) 2017-09-15
BR112012017831B1 (pt) 2021-03-09
BR122015020119B1 (pt) 2021-04-13
EP4056708A1 (en) 2022-09-14
JP2020072676A (ja) 2020-05-14
US20220000147A1 (en) 2022-01-06
HK1221873A1 (zh) 2017-06-16
CN105360351A (zh) 2016-03-02
KR20150013667A (ko) 2015-02-05
JP6705599B2 (ja) 2020-06-03
BR112012017831B8 (pt) 2021-05-25
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BR122015020119B8 (pt) 2021-05-04

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