BR0111852A - Nova interferona para o tratamento de esclerose múltipla - Google Patents
Nova interferona para o tratamento de esclerose múltiplaInfo
- Publication number
- BR0111852A BR0111852A BR0111852-8A BR0111852A BR0111852A BR 0111852 A BR0111852 A BR 0111852A BR 0111852 A BR0111852 A BR 0111852A BR 0111852 A BR0111852 A BR 0111852A
- Authority
- BR
- Brazil
- Prior art keywords
- multiple sclerosis
- treatment
- ifn
- humans
- biologically active
- Prior art date
Links
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 3
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 229920001184 polypeptide Chemical group 0.000 abstract 2
- 108090000765 processed proteins & peptides Chemical group 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 102000004889 Interleukin-6 Human genes 0.000 abstract 1
- 108090001005 Interleukin-6 Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"NOVA INTERFERONA PARA O TRATAMENTO DE ESCLEROSE MúLTIPLA". A presente invenção se refere a novos ácidos nucléicos e seq³ências de polipeptídeos, que codificam uma interferona-beta-2 ("IFN-<225>2"). Uma composição farmacêutica, que compreende um excipiente farmaceuticamente aceitável e uma proporção terapeuticamente eficiente de um polipeptídeo de IFN-<225>2, um de seus fragmentos biologicamente ativos, ou um de seus derivados biologicamente ativos, é útil no tratamento da esclerose múltipla em seres humanos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21204600P | 2000-06-16 | 2000-06-16 | |
US09/881,050 US20020025304A1 (en) | 2000-06-16 | 2001-06-15 | Novel interferon for the treatment of multiple sclerosis |
PCT/US2001/041022 WO2001095929A2 (en) | 2000-06-16 | 2001-06-18 | Interferon for treatment of multiple sclerosis |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111852A true BR0111852A (pt) | 2003-05-20 |
Family
ID=26906704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111852-8A BR0111852A (pt) | 2000-06-16 | 2001-06-18 | Nova interferona para o tratamento de esclerose múltipla |
Country Status (22)
Country | Link |
---|---|
US (1) | US20020025304A1 (pt) |
EP (1) | EP1289541A2 (pt) |
JP (1) | JP2004505021A (pt) |
KR (1) | KR20030009529A (pt) |
CN (1) | CN1436086A (pt) |
AU (1) | AU2001267099A1 (pt) |
BG (1) | BG107370A (pt) |
BR (1) | BR0111852A (pt) |
CA (1) | CA2413077A1 (pt) |
CZ (1) | CZ20024094A3 (pt) |
EE (1) | EE200200693A (pt) |
HU (1) | HUP0300787A2 (pt) |
IL (1) | IL152996A0 (pt) |
LT (1) | LT2002123A (pt) |
MX (1) | MXPA02012308A (pt) |
NO (1) | NO20025964L (pt) |
NZ (1) | NZ522849A (pt) |
PL (1) | PL359562A1 (pt) |
RU (1) | RU2003100517A (pt) |
SI (1) | SI21080A (pt) |
SK (1) | SK17612002A3 (pt) |
WO (1) | WO2001095929A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7314613B2 (en) * | 2002-11-18 | 2008-01-01 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
JP2006506097A (ja) * | 2002-11-18 | 2006-02-23 | マキシジェン, インコーポレイテッド | インターフェロン−αのポリペプチドおよび結合体 |
EP1712992A1 (en) * | 2005-04-11 | 2006-10-18 | Sony Ericsson Mobile Communications AB | Updating of data instructions |
US8895700B2 (en) | 2010-02-18 | 2014-11-25 | Janssen Biotech, Inc. | Monkey homolog of human interferon omega |
DK3411398T3 (da) | 2016-02-05 | 2024-06-24 | Orionis Biosciences BV | Målrettede terapeutiske midler og anvendelse heraf |
AU2018216032B2 (en) | 2017-02-06 | 2022-04-07 | Orionis Biosciences BV | Targeted chimeric proteins and uses thereof |
JP7586579B2 (ja) | 2017-02-06 | 2024-11-19 | オリオンズ バイオサイエンス インコーポレイテッド | 標的化改変型インターフェロン及びその使用 |
WO2019148089A1 (en) | 2018-01-26 | 2019-08-01 | Orionis Biosciences Inc. | Xcr1 binding agents and uses thereof |
WO2024192373A1 (en) * | 2023-03-16 | 2024-09-19 | A-Alpha Bio | Interferon alpha-2 variants |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6372206B1 (en) * | 1989-03-02 | 2002-04-16 | University Of Florida | Orally-administered interferon-TAU compositions and methods |
PL317197A1 (en) * | 1994-05-10 | 1997-03-17 | Immulogic Pharma Corp | Compositions for and method of treating sclerosis multiplex |
US6299869B1 (en) * | 1997-12-08 | 2001-10-09 | Genentech, Inc. | Human interferon-epsilon: a type I interferon |
KR20010052454A (ko) * | 1998-05-29 | 2001-06-25 | 아스트루 마이클 제이 | 재조합 인간 인터페론 베타-1a(ifn-베타-1a) 제제 |
IL142061A0 (en) * | 1998-09-18 | 2002-03-10 | Zymogenetics Inc | Interferon-epsilon |
AU2001255380A1 (en) * | 2000-04-14 | 2001-10-30 | Zymogenetics Inc. | Human interferon, zinf2 |
-
2001
- 2001-06-15 US US09/881,050 patent/US20020025304A1/en not_active Abandoned
- 2001-06-18 BR BR0111852-8A patent/BR0111852A/pt not_active Application Discontinuation
- 2001-06-18 SK SK1761-2002A patent/SK17612002A3/sk unknown
- 2001-06-18 NZ NZ522849A patent/NZ522849A/en unknown
- 2001-06-18 CN CN01811184A patent/CN1436086A/zh active Pending
- 2001-06-18 MX MXPA02012308A patent/MXPA02012308A/es unknown
- 2001-06-18 PL PL01359562A patent/PL359562A1/xx not_active Application Discontinuation
- 2001-06-18 KR KR1020027017090A patent/KR20030009529A/ko not_active Application Discontinuation
- 2001-06-18 JP JP2002510107A patent/JP2004505021A/ja active Pending
- 2001-06-18 EE EEP200200693A patent/EE200200693A/xx unknown
- 2001-06-18 EP EP01944716A patent/EP1289541A2/en not_active Withdrawn
- 2001-06-18 SI SI200120032A patent/SI21080A/sl not_active IP Right Cessation
- 2001-06-18 CZ CZ20024094A patent/CZ20024094A3/cs unknown
- 2001-06-18 RU RU2003100517/15A patent/RU2003100517A/ru not_active Application Discontinuation
- 2001-06-18 HU HU0300787A patent/HUP0300787A2/hu unknown
- 2001-06-18 WO PCT/US2001/041022 patent/WO2001095929A2/en not_active Application Discontinuation
- 2001-06-18 AU AU2001267099A patent/AU2001267099A1/en not_active Abandoned
- 2001-06-18 IL IL15299601A patent/IL152996A0/xx unknown
- 2001-06-18 CA CA002413077A patent/CA2413077A1/en not_active Abandoned
-
2002
- 2002-12-02 LT LT2002123A patent/LT2002123A/xx unknown
- 2002-12-11 BG BG107370A patent/BG107370A/xx unknown
- 2002-12-12 NO NO20025964A patent/NO20025964L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL152996A0 (en) | 2003-06-24 |
WO2001095929A3 (en) | 2002-10-10 |
NO20025964L (no) | 2003-02-14 |
US20020025304A1 (en) | 2002-02-28 |
CA2413077A1 (en) | 2001-12-20 |
NZ522849A (en) | 2004-05-28 |
EE200200693A (et) | 2004-06-15 |
WO2001095929A2 (en) | 2001-12-20 |
CN1436086A (zh) | 2003-08-13 |
CZ20024094A3 (cs) | 2003-05-14 |
AU2001267099A1 (en) | 2001-12-24 |
LT2002123A (en) | 2003-06-25 |
EP1289541A2 (en) | 2003-03-12 |
PL359562A1 (en) | 2004-08-23 |
HUP0300787A2 (hu) | 2003-07-28 |
NO20025964D0 (no) | 2002-12-12 |
BG107370A (en) | 2003-11-28 |
KR20030009529A (ko) | 2003-01-29 |
SK17612002A3 (sk) | 2003-08-05 |
SI21080A (sl) | 2003-06-30 |
JP2004505021A (ja) | 2004-02-19 |
RU2003100517A (ru) | 2004-06-27 |
MXPA02012308A (es) | 2003-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |