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BG105543A - Нови макролидни антибиотици - Google Patents

Нови макролидни антибиотици

Info

Publication number
BG105543A
BG105543A BG105543A BG10554301A BG105543A BG 105543 A BG105543 A BG 105543A BG 105543 A BG105543 A BG 105543A BG 10554301 A BG10554301 A BG 10554301A BG 105543 A BG105543 A BG 105543A
Authority
BG
Bulgaria
Prior art keywords
compounds
macrolide antibiotics
novel macrolide
infections
relates
Prior art date
Application number
BG105543A
Other languages
English (en)
Inventor
Takushi Kaneko
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG105543A publication Critical patent/BG105543A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Изобретението се отнася до съединения и до техни фармацевтично приемливи соли с формула@@в която значенията на радикалите а, R1, R2, R3, R4, R5, R6 иХ са посочени в описанието. Те имат ефикасни антибактериални и антипротозойни свойства и могат да бъдат използвани за лечение на бактериални и протозойни инфекции и заболявания, свързани с такива инфекции. Изобретението се отнася и до фармацевтични състави, съдържащи съединенията, и до методи за лечение на посочените инфекции чрез прилагане на съединенията.
BG105543A 1998-11-03 2001-05-29 Нови макролидни антибиотици BG105543A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10683698P 1998-11-03 1998-11-03
PCT/IB1999/001701 WO2000026224A2 (en) 1998-11-03 1999-10-18 Novel macrolide antibiotics

Publications (1)

Publication Number Publication Date
BG105543A true BG105543A (bg) 2001-12-29

Family

ID=22313524

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105543A BG105543A (bg) 1998-11-03 2001-05-29 Нови макролидни антибиотици

Country Status (34)

Country Link
US (3) US20020040007A1 (bg)
EP (1) EP1124837A2 (bg)
JP (1) JP4043191B2 (bg)
KR (1) KR20010083944A (bg)
CN (1) CN1376160A (bg)
AP (1) AP2001002131A0 (bg)
AU (1) AU5995299A (bg)
BG (1) BG105543A (bg)
BR (1) BR9914998A (bg)
CA (1) CA2349338C (bg)
CO (1) CO5140110A1 (bg)
CZ (1) CZ20011512A3 (bg)
EA (1) EA200100396A1 (bg)
EE (1) EE200100245A (bg)
GT (1) GT199900192A (bg)
HK (1) HK1049010A1 (bg)
HR (1) HRP20010306A2 (bg)
HU (1) HUP0104192A3 (bg)
ID (1) ID28286A (bg)
IL (1) IL142628A0 (bg)
IS (1) IS5919A (bg)
MA (1) MA26703A1 (bg)
NO (1) NO20012155L (bg)
OA (1) OA11670A (bg)
PA (1) PA8485101A1 (bg)
PE (1) PE20001289A1 (bg)
PL (1) PL348114A1 (bg)
SK (1) SK5812001A3 (bg)
SV (1) SV1999000188A (bg)
TN (1) TNSN99205A1 (bg)
TR (4) TR200200434T2 (bg)
UY (1) UY25780A1 (bg)
WO (1) WO2000026224A2 (bg)
ZA (1) ZA200103289B (bg)

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CN1376160A (zh) 1998-11-03 2002-10-23 辉瑞产品公司 新的大环内酯抗生素
PT1147121E (pt) 1999-01-27 2004-04-30 Pfizer Prod Inc Antibioticos cetolidos
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
WO2000063225A2 (en) 1999-04-16 2000-10-26 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
AU4354900A (en) 1999-04-16 2000-11-02 Kosan Biosciences, Inc. Ketolide antibacterials
TR200103395T2 (tr) 1999-05-24 2002-04-22 Pfizer Products Inc. 13-metil eritromisin türevleri.
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
TR200401847T4 (tr) * 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.
EP1794171A2 (en) * 2004-07-28 2007-06-13 Ranbaxy Laboratories, Ltd. Ketolide derivatives as antibacterial agents
WO2006046112A2 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
WO2006067589A1 (en) * 2004-12-21 2006-06-29 Pfizer Products Inc. Macrolides
EP1957508A2 (en) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
US8900601B2 (en) 2010-03-31 2014-12-02 Jennifer Bartels Permeable mixtures, methods and compositions for the skin
BR112015027699B1 (pt) * 2013-05-01 2021-11-30 Neoculi Pty Ltd Uso de robenidina ou um sal terapeuticamente aceitável da mesma, composição farmacêutica antibacteriana e dispositivo médico
RU2537143C1 (ru) * 2013-11-08 2014-12-27 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства РАСХН Препарат для лечения и профилактики мастита у коров
WO2018080072A2 (ko) * 2016-10-27 2018-05-03 한국생명공학연구원 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물

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EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
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Also Published As

Publication number Publication date
AP2001002131A0 (en) 2001-06-30
CA2349338C (en) 2005-12-06
JP4043191B2 (ja) 2008-02-06
GT199900192A (es) 2001-04-26
EA200100396A1 (ru) 2001-10-22
JP2002528553A (ja) 2002-09-03
US20050004047A1 (en) 2005-01-06
AU5995299A (en) 2000-05-22
MA26703A1 (fr) 2004-12-20
HUP0104192A3 (en) 2003-12-29
TR200200435T2 (tr) 2002-07-22
US6835716B2 (en) 2004-12-28
IL142628A0 (en) 2002-03-10
SV1999000188A (es) 2000-10-16
WO2000026224A2 (en) 2000-05-11
CZ20011512A3 (cs) 2001-09-12
KR20010083944A (ko) 2001-09-03
BR9914998A (pt) 2001-07-10
TR200200434T2 (tr) 2002-09-23
US20030013665A1 (en) 2003-01-16
NO20012155L (no) 2001-07-02
EE200100245A (et) 2002-10-15
TR200200436T2 (tr) 2002-06-21
TR200101241T2 (tr) 2001-09-21
HUP0104192A2 (hu) 2002-02-28
HK1049010A1 (zh) 2003-04-25
IS5919A (is) 2001-04-17
NO20012155D0 (no) 2001-05-02
OA11670A (en) 2005-01-12
ID28286A (id) 2001-05-10
CN1376160A (zh) 2002-10-23
US7071170B2 (en) 2006-07-04
CA2349338A1 (en) 2000-05-11
UY25780A1 (es) 2001-08-27
CO5140110A1 (es) 2002-03-22
PE20001289A1 (es) 2000-11-22
HRP20010306A2 (en) 2002-06-30
US20020040007A1 (en) 2002-04-04
WO2000026224A3 (en) 2000-11-16
PA8485101A1 (es) 2002-08-26
EP1124837A2 (en) 2001-08-22
ZA200103289B (en) 2002-08-28
SK5812001A3 (en) 2001-12-03
PL348114A1 (en) 2002-05-06
TNSN99205A1 (fr) 2005-11-10

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