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BE905890A - Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa. - Google Patents

Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa.

Info

Publication number
BE905890A
BE905890A BE0/217509A BE217509A BE905890A BE 905890 A BE905890 A BE 905890A BE 0/217509 A BE0/217509 A BE 0/217509A BE 217509 A BE217509 A BE 217509A BE 905890 A BE905890 A BE 905890A
Authority
BE
Belgium
Prior art keywords
monoclonal antibodies
cross
protection against
aeruginosa serotypes
reaction
Prior art date
Application number
BE0/217509A
Other languages
English (en)
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of BE905890A publication Critical patent/BE905890A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

On a produit des lignées de cellules secrétant des anticorps monoclonaux humains capables de se lier aux molécules de lipopolysaccharide de sérotypes IATS choisis de Pseudomanas aeruginosa. Sont aussi comprises des compositions pharmaceutiques contenant ces anticorps, en combinaison avec d'autres anticorps monoclonaux, des fractions de plasma sanguin et des agents antimicrobiens, ainsi que l'utilisation prophylactactique et thérapeutique de ces compositions dans le traitement des infections.
BE0/217509A 1985-12-10 1986-12-10 Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa. BE905890A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80739485A 1985-12-10 1985-12-10
US93117986A 1986-11-24 1986-11-24

Publications (1)

Publication Number Publication Date
BE905890A true BE905890A (fr) 1987-06-10

Family

ID=27123006

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217509A BE905890A (fr) 1985-12-10 1986-12-10 Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa.

Country Status (21)

Country Link
US (4) US5378812A (fr)
JP (1) JPH07116237B2 (fr)
KR (1) KR910008361B1 (fr)
CN (1) CN86108380A (fr)
AT (1) AT400441B (fr)
BE (1) BE905890A (fr)
CH (1) CH677362A5 (fr)
DE (1) DE3642095C2 (fr)
DK (1) DK594586A (fr)
FI (1) FI86377C (fr)
FR (1) FR2593826B1 (fr)
GB (1) GB2185266B (fr)
HU (1) HUT41836A (fr)
IE (1) IE59741B1 (fr)
IT (1) IT1199735B (fr)
LU (1) LU86711A1 (fr)
NL (1) NL8603132A (fr)
NO (1) NO178718C (fr)
NZ (1) NZ218499A (fr)
PT (1) PT83894B (fr)
SE (1) SE468831B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
AU615162B2 (en) * 1986-07-03 1991-09-26 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
EP0256713A3 (fr) * 1986-08-06 1989-02-15 Merck & Co. Inc. Anticorps humains thérapeutiques anti-pseudomonas aeruginosa
US5521085A (en) * 1986-12-15 1996-05-28 Mitsui Toatsu Chemicals, Inc. Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes
DE3786173T2 (de) * 1986-12-15 1993-12-16 Mitsui Toatsu Chemicals Menschlicher monoklonaler antikörper und arzneimittel zur prophylaxe und behandlung von infektiösen krankheiten.
WO1990011350A1 (fr) * 1989-03-20 1990-10-04 Mitsui Toatsu Chemicals, Inc. Anticorps monoclonal humain reagissant avec le pseudomonas aeruginosa, cellule produisant cet anticorps, procede de production et preparation pharmaceutique
JPH01197500A (ja) * 1988-01-29 1989-08-09 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
CA1341375C (fr) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions pour le traitement et la prevention d'infections dues a des bacteries gram negatif, ainsi que leurs methodes d'utilisation
EP0382031A3 (fr) * 1989-02-10 1991-06-26 Miles Inc. Anticorps monoclonaux dans une préparation de globuline d'immunsérum
US4994269A (en) * 1989-03-17 1991-02-19 Miles Inc. Topical use of antibodies for prevention or treatment of pseudomonas infections
JPH02283294A (ja) * 1989-04-24 1990-11-20 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
JPH0329196A (ja) * 1989-05-09 1991-02-07 Advanced Micro Devicds Inc センス増幅器
US5858728A (en) * 1991-03-13 1999-01-12 Common Services Agency Monoclonal antibody against LPS core
US20030096315A1 (en) 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
WO2003063693A2 (fr) * 2002-01-31 2003-08-07 Expressive Constructs, Inc. Methode de detection de micro-organismes
EP1506217A4 (fr) * 2002-05-29 2006-04-12 Jackson H M Found Military Med Methodes d'identification de biomarqueurs genomiques et proteomiques pour la mucoviscidose, jeux ordonnes d'echantillons comprenant ces biomarqueurs et methodes d'utilisation de ces jeux ordonnes d'echantillons
JP5271475B2 (ja) 2002-11-26 2013-08-21 ザ ユニヴァーシティー オヴ シカゴ 微生物媒介上皮疾患の予防及び治療のための材料並びに方法
US20060257955A1 (en) * 2003-01-31 2006-11-16 Colpas Gerard J Method for detecting escherichia coli
DE602004011105T2 (de) 2003-11-03 2008-12-18 Ethicon, Inc. Verfahren, peptide und biosensoren mit eignung zum nachweis eines breiten spektrums von bakterien
EP1690875A1 (fr) * 2005-02-14 2006-08-16 Kenta Biotech AG Anticorps monoclonal humain specifique pour lipoplysaccharides (LPS) de la Pseudomonas aeruginosa serotype IATS O11
AU2007245258B2 (en) * 2006-05-01 2013-09-19 Bioness Neuromodulation Ltd. Improved functional electrical stimulation systems
EP2393515A1 (fr) * 2009-02-04 2011-12-14 Kalobios Pharmaceuticals, Inc. Antibiotique en combinaison et thérapie antibiotique pour traiter une infection par pseudomonas aeruginosa
CN102858977A (zh) * 2010-02-18 2013-01-02 明治制果药业株式会社 铜绿假单胞菌g血清型脂多糖抗体
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
JPS59137497A (ja) * 1983-01-20 1984-08-07 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア 抗原特異的免疫グロブリン生産性ヒト／ヒトハイブリド−マ及びその生産する抗体
JPS58216125A (ja) * 1982-06-09 1983-12-15 Asahi Chem Ind Co Ltd ヒト抗体の産生方法
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
WO1985002685A1 (fr) * 1983-12-12 1985-06-20 Meru, Inc. Procede et substances permettant l'identification de micro-organismes produisant du lipopolysaccharide
US4683196A (en) * 1983-12-12 1987-07-28 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
JPS60248625A (ja) * 1984-05-25 1985-12-09 Mitsui Toatsu Chem Inc 抗緑膿菌モノクロ−ナル抗体、その製法ならびに用途
JP2565303B2 (ja) * 1984-05-25 1996-12-18 三井東圧化学株式会社 緑膿菌感染症の予防治療剤
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
AU597877B2 (en) * 1984-12-26 1990-06-14 Teijin Limited Anti-pseudomonas aeruginosa human monoclonal antibody
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
JPS6229175A (ja) * 1985-07-29 1987-02-07 Nippon Telegr & Teleph Corp <Ntt> 電界効果型トランジスタの製造方法
EP0211352B1 (fr) * 1985-08-01 1994-03-16 Miles Inc. Anticorps protecteurs contre des déterminants sérotypiques d'antigènes flagellaires
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus
AU615162B2 (en) * 1986-07-03 1991-09-26 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
EP0256713A3 (fr) * 1986-08-06 1989-02-15 Merck & Co. Inc. Anticorps humains thérapeutiques anti-pseudomonas aeruginosa

Also Published As

Publication number Publication date
HUT41836A (en) 1987-05-28
FI865027A0 (fi) 1986-12-10
NL8603132A (nl) 1987-07-01
ATA328286A (de) 1995-05-15
NO178718C (no) 1996-05-22
US5627067A (en) 1997-05-06
NO864971D0 (no) 1986-12-10
DK594586D0 (da) 1986-12-10
DE3642095C2 (de) 1998-10-01
CH677362A5 (fr) 1991-05-15
US5378812A (en) 1995-01-03
KR870005648A (ko) 1987-07-06
FI86377B (fi) 1992-05-15
US5628996A (en) 1997-05-13
NZ218499A (en) 1990-04-26
FR2593826B1 (fr) 1990-11-16
PT83894A (en) 1987-01-01
FR2593826A1 (fr) 1987-08-07
IE863230L (en) 1987-06-10
JPH07116237B2 (ja) 1995-12-13
IT1199735B (it) 1988-12-30
AT400441B (de) 1995-12-27
PT83894B (pt) 1989-07-31
DK594586A (da) 1987-06-11
CN86108380A (zh) 1987-10-28
IE59741B1 (en) 1994-03-23
FI86377C (fi) 1992-08-25
KR910008361B1 (ko) 1991-10-12
LU86711A1 (fr) 1988-07-14
SE8605295D0 (sv) 1986-12-10
SE468831B (sv) 1993-03-29
GB2185266B (en) 1990-09-05
JPS62187417A (ja) 1987-08-15
FI865027A (fi) 1987-06-11
US5662905A (en) 1997-09-02
NO178718B (no) 1996-02-12
DE3642095A1 (de) 1987-07-02
NO864971L (no) 1987-06-11
GB8629540D0 (en) 1987-01-21
SE8605295L (sv) 1987-06-11
GB2185266A (en) 1987-07-15
IT8622630A0 (it) 1986-12-10

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GENETIC SYSTEMS CORP.

Effective date: 20001231