[go: up one dir, main page]

BE848639A - Dispositif permettant de liberer des substances par osmose dans un milieu liquide, - Google Patents

Dispositif permettant de liberer des substances par osmose dans un milieu liquide,

Info

Publication number
BE848639A
BE848639A BE172602A BE172602A BE848639A BE 848639 A BE848639 A BE 848639A BE 172602 A BE172602 A BE 172602A BE 172602 A BE172602 A BE 172602A BE 848639 A BE848639 A BE 848639A
Authority
BE
Belgium
Prior art keywords
osmosis
substances
release
liquid medium
device allowing
Prior art date
Application number
BE172602A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE848639A publication Critical patent/BE848639A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Coating Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
BE172602A 1975-11-24 1976-11-23 Dispositif permettant de liberer des substances par osmose dans un milieu liquide, BE848639A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/634,859 US4077407A (en) 1975-11-24 1975-11-24 Osmotic devices having composite walls

Publications (1)

Publication Number Publication Date
BE848639A true BE848639A (fr) 1977-03-16

Family

ID=24545453

Family Applications (1)

Application Number Title Priority Date Filing Date
BE172602A BE848639A (fr) 1975-11-24 1976-11-23 Dispositif permettant de liberer des substances par osmose dans un milieu liquide,

Country Status (20)

Country Link
US (2) US4077407A (fr)
JP (1) JPS6058724B2 (fr)
AR (1) AR216642A1 (fr)
AT (1) AT356821B (fr)
AU (1) AU506506B2 (fr)
BE (1) BE848639A (fr)
CA (1) CA1074653A (fr)
CH (1) CH629957A5 (fr)
DE (1) DE2653232A1 (fr)
DK (1) DK150533C (fr)
ES (1) ES453530A1 (fr)
FR (1) FR2332008A1 (fr)
GB (1) GB1528265A (fr)
IE (1) IE44264B1 (fr)
IL (1) IL50851A (fr)
IT (1) IT1070481B (fr)
MX (1) MX157537A (fr)
NL (1) NL187298C (fr)
SE (1) SE430301B (fr)
ZA (1) ZA766900B (fr)

Families Citing this family (488)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4445885A (en) * 1977-02-16 1984-05-01 Unitika, Ltd. Insulin releasing supplier
US4519909A (en) * 1977-07-11 1985-05-28 Akzona Incorporated Microporous products
US4159720A (en) * 1977-11-28 1979-07-03 Burton Andrew F Infusion of liquids into tissue
US4304672A (en) * 1978-04-04 1981-12-08 Sbr Lab, Inc. Stored blood and liquid system pH control method and apparatus
NZ192673A (en) * 1979-02-02 1984-07-06 Merck & Co Inc Ophthalmic compositions for lowering intraocular pressure
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
US4357236A (en) * 1979-05-17 1982-11-02 Borg-Warner Corporation Automatic addition of a corrosion inhibitor to a coolant system by osmotic pressure
DE3068986D1 (en) * 1980-01-28 1984-09-27 Merck & Co Inc Ophthalmic inserts for lowering intraocular pressure comprising carbonic anhydrase inhibitors
IE50901B1 (en) * 1980-03-04 1986-08-06 Merck & Co Inc Ophthalmic compositions of carbonic anhydrase inhibitors for topical application in the treatment of elevated intraocular pressure
JPS57140710A (en) * 1981-02-24 1982-08-31 Shionogi & Co Ltd Capsule agent for rectal administration
JPH0245604B2 (fr) * 1980-07-09 1990-10-11 Yunibaashitei Obu Furorida Za
US4300558A (en) * 1980-07-18 1981-11-17 Alza Corporation Self-driven fluid dispenser
US4439195A (en) * 1980-10-14 1984-03-27 Alza Corporation Theophylline therapy
US4364385A (en) * 1981-03-13 1982-12-21 Lossef Steven V Insulin delivery device
US4484921A (en) * 1982-02-01 1984-11-27 Alza Corporation Theophylline therapy utilizing osmotic delivery
JPS5931701A (ja) * 1982-08-16 1984-02-20 Nitto Electric Ind Co Ltd 液状活性物質含有膜及びその製造方法
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
US4478596A (en) * 1982-11-26 1984-10-23 Michelson Paul E Delivery system for physiologically active agents
US4613330A (en) * 1982-11-26 1986-09-23 Michelson Paul E Delivery system for desired agents
IE53703B1 (en) * 1982-12-13 1989-01-18 Elan Corp Plc Drug delivery device
US4722937A (en) * 1984-06-29 1988-02-02 Joseph Jacob Antitoxin vaginal products and catamenials
US4722936A (en) * 1983-05-05 1988-02-02 Joseph Jacob Deodorization vaginal products and catamenials
US4585792A (en) * 1983-05-05 1986-04-29 Technology Unlimited Inc. Protective additive to vaginal products and catamenials
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4851229A (en) * 1983-12-01 1989-07-25 Alza Corporation Composition comprising a therapeutic agent and a modulating agent
US4751071A (en) * 1983-12-01 1988-06-14 Alza Corporation Composition comprising salbutamol
US4777049A (en) * 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
GB2150830B (en) * 1983-12-05 1987-08-19 Alza Corp Drug dispenser
US4761159A (en) * 1984-01-23 1988-08-02 Lewis Knox Method of chemical deodorization of articles and solutions used in medical and biological procedures
US4729793A (en) * 1985-08-09 1988-03-08 Alza Corporation Composition for manufacturing wall of dispensing device
US4716031A (en) * 1984-03-21 1987-12-29 Alza Corporation Drug dispenser comprising a multiplicity of members acting together for successfully dispensing drug
US4663148A (en) * 1984-03-21 1987-05-05 Alza Corporation Dispenser comprising telescopically engaging members
US4800056A (en) * 1984-03-21 1989-01-24 Alza Corporation Process for making dispenser with cooperating elements
US4814180A (en) * 1984-03-21 1989-03-21 Alza Corporation Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container
US4692326A (en) * 1984-03-21 1987-09-08 Alza Corporation Dispenser comprising inner positioned soft or hard capsule
US4663149A (en) * 1984-03-21 1987-05-05 Alza Corporation Dispenser comprising inner and outer walls functioning as cooperative unit
US4615698A (en) * 1984-03-23 1986-10-07 Alza Corporation Total agent osmotic delivery system
US4649075A (en) * 1984-08-09 1987-03-10 Leonora Jost Transdermal and transmucosal vortexed foam devices and the method of making
US4743247A (en) * 1984-08-13 1988-05-10 Alza Corporation Process for manufacturing dosage form
GB8422876D0 (en) * 1984-09-11 1984-10-17 Secr Defence Silicon implant devices
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4655766A (en) * 1985-08-01 1987-04-07 Alza Corporation Fluid imbibing pump with self-regulating skin patch
US4756314A (en) * 1985-10-28 1988-07-12 Alza Corporation Sweat collection patch
US5204339A (en) * 1986-01-31 1993-04-20 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
CA1293192C (fr) * 1986-01-31 1991-12-17 James V. Peck Compositions comprenant des azacycloalcanes substitues en 1
US4867969A (en) * 1986-02-07 1989-09-19 Alza Corporation Hydrogel formulation for administering non-steroidal drugs
US4971790A (en) * 1986-02-07 1990-11-20 Alza Corporation Dosage form for lessening irritation of mocusa
US4747847A (en) * 1986-02-07 1988-05-31 Alza Corporation System for delivering potassium chloride with enhanced bioacceptability
US4786500A (en) * 1986-06-26 1988-11-22 Alza Corporation Programmable agent delivery system
US4927632A (en) * 1986-06-26 1990-05-22 Alza Corporation Selective pulsed drug delivery system
US4885868A (en) * 1986-12-03 1989-12-12 Cornell Research Foundation, Inc. Banding techniques for plant propagation
US4917688A (en) * 1987-01-14 1990-04-17 Nelson Research & Development Co. Bandage for transdermal delivery of systemically-active drug
US4832690A (en) * 1987-01-23 1989-05-23 Baxter International Inc. Needle-pierceable cartridge for drug delivery
US4801461A (en) * 1987-01-28 1989-01-31 Alza Corporation Pseudoephedrine dosage form
US4915952A (en) * 1987-02-27 1990-04-10 Alza Corporation Composition comprising drug, HPC, HPMC and PEO
US5023076A (en) * 1987-02-27 1991-06-11 Alza Corporation Lamina comprising carboxyvinyl polymer
US4731122A (en) * 1987-03-30 1988-03-15 Alza Corporation Process for manufacturing a thermoplastic molding composition
US5391381A (en) * 1987-06-25 1995-02-21 Alza Corporation Dispenser capable of delivering plurality of drug units
US5340590A (en) * 1987-06-25 1994-08-23 Alza Corporation Delivery system with bilayer osmotic engine
US5236689A (en) * 1987-06-25 1993-08-17 Alza Corporation Multi-unit delivery system
US4795641A (en) * 1987-08-20 1989-01-03 Eastman Kodak Company Polymer blends having reverse phase morphology for controlled delivery of bioactive agents
US4920101A (en) * 1987-09-30 1990-04-24 Nelson Research & Development Co. Compositions comprising 1-oxo- or thiohydrocarbyl substituted azacycloaklkanes
US4879275A (en) * 1987-09-30 1989-11-07 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agent
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
US4877618A (en) * 1988-03-18 1989-10-31 Reed Jr Fred D Transdermal drug delivery device
US4855141A (en) * 1988-03-25 1989-08-08 Alza Corporation Device comprising means for protecting and dispensing fluid sensitive medicament
US4996060A (en) * 1988-03-25 1991-02-26 Alza Corporation Device comprising liner for protecting fluid sensitive medicament
US4959218A (en) * 1988-03-25 1990-09-25 Alza Corporation Method for delivering somatotropin to an animal
US5006346A (en) * 1988-04-28 1991-04-09 Alza Corporation Delivery system
US5024842A (en) * 1988-04-28 1991-06-18 Alza Corporation Annealed coats
US4931285A (en) * 1988-04-28 1990-06-05 Alza Corporation Aqueous based pharmaceutical coating composition for dosage forms
US5160743A (en) * 1988-04-28 1992-11-03 Alza Corporation Annealed composition for pharmaceutically acceptable drug
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5037420A (en) * 1988-12-13 1991-08-06 Alza Corporation Delivery system comprising two sections for delivering somatotropin
US5059423A (en) * 1988-12-13 1991-10-22 Alza Corporation Delivery system comprising biocompatible beneficial agent formulation
US5174999A (en) * 1988-12-13 1992-12-29 Alza Corporation Delivery system comprising fluid ingress and drug egress
US5135523A (en) * 1988-12-13 1992-08-04 Alza Corporation Delivery system for administering agent to ruminants and swine
US5110596A (en) * 1988-12-13 1992-05-05 Alza Corporation Delivery system comprising means for delivering agent to livestock
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US5057318A (en) * 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
US5019396A (en) * 1989-05-12 1991-05-28 Alza Corporation Delivery dispenser for treating cardiac arrhythmias
US5273752A (en) * 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5126142A (en) * 1989-07-18 1992-06-30 Alza Corporation Dispenser comprising ionophore
US5035897A (en) * 1989-09-05 1991-07-30 Alza Corporation Dosage form for delivering soluble or insoluble drugs
US6361795B1 (en) * 1989-09-05 2002-03-26 Alza Corporation Method for lowering blood glucose
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5098714A (en) * 1989-11-16 1992-03-24 Alza Corporation Osmotic, oral dosage form for fertility control
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5223266A (en) * 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
US5474785A (en) * 1990-01-24 1995-12-12 Alza Corporation Delivery system comprising means for controlling internal pressure
US5192550A (en) * 1990-05-07 1993-03-09 Alza Corporation Dosage form for treating central nervous system disorders
US5190763A (en) * 1990-05-07 1993-03-02 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5221536A (en) 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5234694A (en) * 1990-07-11 1993-08-10 Alza Corporation Method for increasing feed efficiency in animals
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5238687A (en) * 1990-07-11 1993-08-24 Alza Corporation Delivery device with a protective sleeve
US5234693A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5180591A (en) * 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
WO1992002212A2 (fr) * 1990-08-07 1992-02-20 Pfizer Inc. Emploi de membranes a polymerisation interfaciale dans des dispositifs de liberation
US5431921A (en) * 1990-09-28 1995-07-11 Pfizer Inc Dispensing device containing a hydrophobic medium
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US6764697B1 (en) 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
US5178867A (en) * 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
US5240713A (en) * 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5266332A (en) * 1991-12-06 1993-11-30 Alza Corporation Method for administering anti-Parkinson drug
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5254349A (en) * 1991-12-06 1993-10-19 Alza Corporation Process for lessening irritation caused by drug
US5200194A (en) * 1991-12-18 1993-04-06 Alza Corporation Oral osmotic device
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
US5358721A (en) * 1992-12-04 1994-10-25 Alza Corporation Antiviral therapy
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
US6129930A (en) * 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6080428A (en) * 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
US20080045573A1 (en) * 1993-09-20 2008-02-21 Bova David J Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia
US6183778B1 (en) 1993-09-21 2001-02-06 Jagotec Ag Pharmaceutical tablet capable of liberating one or more drugs at different release rates
US5532003A (en) * 1994-01-18 1996-07-02 Alza Corporation Pentoxifylline therapy
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US5525279A (en) * 1994-04-04 1996-06-11 Sekisui Kagaku Kogyo K.K. Method of forming a granulocyte adsorbing carrier and granulocyte remover
US20040191314A1 (en) * 1994-04-28 2004-09-30 Frank Jao Antiepileptic dosage form and process for protecting antiepileptic drug
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
US5698224A (en) * 1994-06-27 1997-12-16 Alza Corporation Tacrine therapy
US5914131A (en) * 1994-07-07 1999-06-22 Alza Corporation Hydromorphone therapy
US5595759A (en) * 1994-11-10 1997-01-21 Alza Corporation Process for providing therapeutic composition
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US5713852A (en) * 1995-06-07 1998-02-03 Alza Corporation Oral dosage and method for treating painful conditions of the oral cavity
IT1282576B1 (it) 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US7094422B2 (en) * 1996-02-19 2006-08-22 Acrux Dds Pty Ltd. Topical delivery of antifungal agents
EP0914178B1 (fr) 1996-06-18 2003-03-12 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US5800624A (en) * 1996-10-22 1998-09-01 University Of Notre Dame Membrane process for separating carbohydrates
US6361796B1 (en) * 1996-10-25 2002-03-26 Shire Laboratories, Inc. Soluble form osmotic dose delivery system
DE69735002T2 (de) * 1996-10-25 2006-10-26 Shire Laboratories, Inc. Osmotisches Verabreichungssystem für lösliche Dosen
US6110499A (en) * 1997-07-24 2000-08-29 Alza Corporation Phenytoin therapy
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6514530B2 (en) 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
IN186245B (fr) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US20040062799A1 (en) * 1997-09-29 2004-04-01 Ayer Atul D. Therapeutic composition and delivery system for administering drug
DE69805001T2 (de) 1997-12-05 2002-08-22 Alza Corp., Palo Alto Osmotische darreichungsform mit zwei mantelschichten
RU2241458C2 (ru) * 1997-12-22 2004-12-10 Эро-Селтик, С.А. Комбинации агонист/антагонист опиоида
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
US6228863B1 (en) * 1997-12-22 2001-05-08 Euro-Celtique S.A. Method of preventing abuse of opioid dosage forms
PT1041975E (pt) * 1997-12-22 2003-01-31 Alza Corp Membranas de controlo de taxa para dispositivos de fornecimento controlado de drogas
US8524277B2 (en) * 1998-03-06 2013-09-03 Alza Corporation Extended release dosage form
US6245357B1 (en) 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US20010038855A1 (en) * 1998-06-05 2001-11-08 Desjardin Michael A. Dosage form for administering prescribed dose
US6099862A (en) 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
US6551613B1 (en) * 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
US6174547B1 (en) * 1999-07-14 2001-01-16 Alza Corporation Dosage form comprising liquid formulation
GB9822854D0 (en) 1998-10-21 1998-12-16 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
US6706282B1 (en) 1998-11-02 2004-03-16 Evangeline Cruz Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones
IL142807A0 (en) 1998-11-02 2002-03-10 Alza Corp Controlled delivery of active agents
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
EP1152709B1 (fr) 1999-02-02 2005-01-12 Wright Medical Technology, Inc. Composite a liberation controlee
US20040121014A1 (en) * 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6319510B1 (en) 1999-04-20 2001-11-20 Alayne Yates Gum pad for delivery of medication to mucosal tissues
CO5210862A1 (es) 1999-09-15 2002-10-30 Alza Corp Formas de dosificacion y metodos para proporcionar efectiva terapia de reboxetina con dosificacion de una vez al dia
KR100738276B1 (ko) * 1999-12-09 2007-07-12 알자 코포레이션 항바이러스성 약제
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
EP2263658A1 (fr) 2000-10-30 2010-12-22 Euro-Celtique S.A. Formulations d'hydrocodone à liberation lente
US20060034922A1 (en) * 2000-11-03 2006-02-16 Andrx Labs, Llc Controlled release metformin compositions
AU2002230830A1 (en) 2000-11-03 2002-05-15 Andrx Labs, Llc Controlled release metformin compositions
US6866866B1 (en) * 2000-11-03 2005-03-15 Andrx Labs, Llc Controlled release metformin compositions
US6790459B1 (en) 2000-11-03 2004-09-14 Andrx Labs, Llc Methods for treating diabetes via administration of controlled release metformin
US6632217B2 (en) * 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
ATE438418T1 (de) * 2001-05-01 2009-08-15 Av Topchiev Inst Petrochemical Hydrogel-zusammensetzungen
DE60239528D1 (de) 2001-05-01 2011-05-05 Corium International Redwood City Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US8206738B2 (en) * 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
ES2361148T3 (es) 2001-05-11 2011-06-14 Endo Pharmaceuticals Inc. Forma de dosificación de opioides de liberación controlada resistente al abuso.
EP2316394B1 (fr) 2001-06-12 2016-11-23 The Johns Hopkins University Dispositif à réservoir pour administration intraoculaire de médicaments
SI1416842T1 (sl) 2001-07-18 2009-06-30 Euro Celtique Sa Farmacevtske kombinacije oksikodona in naloksona
US20030157168A1 (en) * 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
MXPA04002891A (es) * 2001-09-28 2005-06-20 Johnson & Johnson Composicion farmaceutica a base de pasta de azucar.
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
WO2003051341A1 (fr) * 2001-12-18 2003-06-26 Alza Corporation Forme posologique permettant d'obtenir des modeles d'apport de medicaments variant dans le temps
WO2003053401A2 (fr) * 2001-12-19 2003-07-03 Alza Corporation Preparation et forme posologique pour l'augmentation de la biodisponibilite buccale de macromolecules hydrophiles
US20030232078A1 (en) * 2001-12-19 2003-12-18 Dong Liang C. Formulation & dosage form for the controlled delivery of therapeutic agents
US20030161882A1 (en) * 2002-02-01 2003-08-28 Waterman Kenneth C. Osmotic delivery system
US20030175346A1 (en) * 2002-02-01 2003-09-18 Anne Billotte Osmotic delivery system
US7004171B2 (en) * 2002-02-25 2006-02-28 Hi-Gienic Intra Vaginal Technologies Ltd. System for transvaginal drug delivery
ITMI20020515A1 (it) 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
DE20321531U1 (de) * 2002-04-05 2007-11-22 Euro-Celtique S.A. Lagerstabiles pharmazeutisches Präparat, das Oxycodon und Naloxon umfaßt
US20030224051A1 (en) * 2002-05-31 2003-12-04 Fink Tracy A. Dosage forms and compositions for osmotic delivery of variable dosages of oxycodone
ATE419830T1 (de) * 2002-04-29 2009-01-15 Alza Corp Methoden und darreichungsformen zur kontrollierten freisetzung von oxykodon
US20050106249A1 (en) * 2002-04-29 2005-05-19 Stephen Hwang Once-a-day, oral, controlled-release, oxycodone dosage forms
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US20040052848A1 (en) * 2002-05-23 2004-03-18 Xiu-Xiu Cheng Biguanide formulations
US20030224045A1 (en) * 2002-05-29 2003-12-04 Chien-Hsuan Han Combination immediate release sustained release levodopa/carbidopa dosage forms
US7094427B2 (en) * 2002-05-29 2006-08-22 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20040166159A1 (en) * 2002-05-29 2004-08-26 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
US20050175690A1 (en) * 2003-12-29 2005-08-11 David Edgren Novel drug compositions and dosage forms
US20050175697A1 (en) * 2003-12-29 2005-08-11 David Edgren Novel drug compositions and dosage forms of topiramate
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
AU2003245738A1 (en) * 2002-06-28 2004-01-19 Alza Corporation C/O Johnson & Johnson Oral dosage from comprising a liquid active agent formulation andcontrolling release thereof by an expandable osmotic composition
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
EP1534238A1 (fr) * 2002-07-29 2005-06-01 ALZA Corporation Formulations et formes posologiques pour une administration controlee de topiramate
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
CA2499597C (fr) 2002-09-20 2012-01-17 Unchalee Kositprapa Nouvelle preparation pharmaceutique contenant un biguanide et un derive de la thiazolidinedione
US7785627B2 (en) * 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US20050051922A1 (en) * 2002-09-20 2005-03-10 Avinash Nangia Pharmaceutical composition with sodium lauryl sulfate as an extra-granular absorption/compression enhancer and the process to make the same
US20050048119A1 (en) * 2002-09-20 2005-03-03 Avinash Nangia Controlled release composition with semi-permeable membrane and poloxamer flux enhancer
UY28056A1 (es) * 2002-10-31 2003-12-31 Alza Corp Formas de dosificacion que proporcionan la liberacion ascendente de una formulacion liquida.
AR041745A1 (es) * 2002-10-31 2005-05-26 Alza Corp Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrofobos
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
EP2218448B1 (fr) 2002-12-13 2015-09-23 Durect Corporation Forme d'administration orale de medicaments comprenant un vehicule liquide de haute viscosite
JP2006511541A (ja) * 2002-12-17 2006-04-06 アボット ゲーエムベーハー ウント カンパニー カーゲー フェノフィブル酸、その生理学的に許容し得る塩または誘導体を含有してなる製剤
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
US7259186B2 (en) * 2002-12-17 2007-08-21 Abbott Laboratories Salts of fenofibric acid and pharmaceutical formulations thereof
WO2004064772A2 (fr) * 2003-01-14 2004-08-05 Alza Corporation Methodes et formes posologiques comprenant des couches a viscosite modifiee
WO2004071497A1 (fr) * 2003-02-11 2004-08-26 Alza Corporation Methodes et formes dosifiees presentant une geometrie de couche modifiee
MY135852A (en) * 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
US7611480B2 (en) * 2003-04-24 2009-11-03 Levy Mark M Gastrointestinal bioreactor
KR20060039867A (ko) * 2003-06-20 2006-05-09 바이럴 게노믹스, 인크. Ｈｉｖ 치료를 위한 조성물 및 방법
CN1863557B (zh) 2003-06-26 2010-06-16 普西维达公司 原位胶凝的药物递送系统
EP2112920B1 (fr) * 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Capsules contenant un inhibiteur de la pompe a protons comprenant des unites secondaires differemment structurees permettant une liberation retardee de l'ingredient actif
TWI367103B (en) * 2003-06-26 2012-07-01 Psivida Inc Bioerodible sustained release drug delivery systems
EP1653922A2 (fr) * 2003-08-06 2006-05-10 Alza Corporation Administration reguliere de topiramate pendant une periode prolongee a formulation de dispersion amelioree
AU2004268549A1 (en) * 2003-08-22 2005-03-10 Alza Corporation Stepwise delivery of topiramate over prolonged period of time
AU2004268661A1 (en) * 2003-09-02 2005-03-10 Alza Corporation Novel drug compositions and dosage forms of topiramate
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
EP1663229B1 (fr) 2003-09-25 2010-04-14 Euro-Celtique S.A. Combinaisons pharmaceutiques d'hydrocodone et de naltrexone
ATE504288T1 (de) 2003-09-26 2011-04-15 Alza Corp Oros-push-stick für die kontrollierte abgabe von wirkstoffen
EP1680094A1 (fr) * 2003-09-26 2006-07-19 Alza Corporation Preparations a liberation regulee a base d'analgesiques opioides et non opioides
US8246986B2 (en) * 2003-09-26 2012-08-21 Alza Corporation Drug coating providing high drug loading
US20050186273A1 (en) * 2003-09-26 2005-08-25 Si-Hong Yum Controlled release dosage form including a banded engine
CA2540059C (fr) 2003-09-26 2013-08-06 Alza Corporation Formulations a liberation commandee presentant un taux croisssant de liberation
WO2005030180A1 (fr) * 2003-09-26 2005-04-07 Alza Corporation Formes pharmaceutiques osmotiques pour l'administration controlee d'alprazolame
US20050112190A1 (en) * 2003-09-26 2005-05-26 Wiser Lauren M. Dosage form for controlled release of an active agent formulation
JP2007509976A (ja) * 2003-10-31 2007-04-19 アルザ・コーポレーシヨン 増加された鉄の吸収のための組成物及び投与形態
US20050095288A1 (en) * 2003-11-03 2005-05-05 Andrx Labs, Llc Decongestant and expectorant tablets
CN1905857A (zh) * 2003-11-14 2007-01-31 阿尔扎公司 液体剂型的托吡酯的受控释放
US8734850B2 (en) * 2003-11-25 2014-05-27 Flamel Technologies Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
US20050129764A1 (en) * 2003-12-11 2005-06-16 Vergez Juan A. Osmotic device containing licofelone
KR20060123493A (ko) * 2003-12-23 2006-12-01 알자 코포레이션 제어된 전달을 위한 약물 조성물의 용해도를 증가시키는방법 및 제형
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
WO2005074894A1 (fr) 2004-01-30 2005-08-18 Corium International Film a dissolution rapide pour la delivrance d'agent actif
US20050196448A1 (en) * 2004-03-05 2005-09-08 Hai Yong Huang Polymeric compositions and dosage forms comprising the same
US20050196446A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196447A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196442A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
TWI483944B (zh) * 2004-03-30 2015-05-11 Euro Celtique Sa 含有小於２５ｐｐｍ１４-羥可待因酮之羥可酮鹽酸鹽組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝
US20060009425A1 (en) * 2004-05-28 2006-01-12 Leticia Delgado-Herrera Oral formulations of paricalcitol
EP1604666A1 (fr) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioides pour le traitement de la bronchopneumopathie chronique obstructive
EP1604667A1 (fr) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioides pour le traitement des impatiences des membres inférieurs
PT1765292T (pt) 2004-06-12 2017-12-29 Collegium Pharmaceutical Inc Formulações de fármacos dissuasoras de abuso
US20050276848A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release neutralized divalproex sodium
US7713550B2 (en) * 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
US20050287185A1 (en) * 2004-06-23 2005-12-29 David Wong Extended release oxybutynin formulation
WO2006007351A2 (fr) * 2004-06-28 2006-01-19 Alza Corporation Forme posologique orale a liberation controlee par compression
US20050287213A1 (en) * 2004-06-28 2005-12-29 Wong Patrick S Dosage forms for low solubility and or low dissolution rate free acid pharmaceutical agents
EP1761265A2 (fr) * 2004-06-28 2007-03-14 ALZA Corporation Systeme d'administration par voie orale comprenant un complexe medicament/polymere
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060001011A1 (en) * 2004-07-02 2006-01-05 Wilson Neil R Surface conditioner for powder coating systems
ES2526700T3 (es) 2004-08-05 2015-01-14 Corium International, Inc. Composición de adhesivo
CA2577583A1 (fr) * 2004-08-19 2006-03-02 Alza Corporation Formes posologiques renfermant une formulation d'agent actif nanoparticulaire a liberation retardee et procedes
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8541026B2 (en) * 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
PL2377557T3 (pl) 2004-11-24 2017-05-31 Meda Pharmaceuticals Inc. Kompozycje zawierające azelastynę i sposoby ich zastosowania
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US8252331B2 (en) * 2004-12-03 2012-08-28 Osmotica Kereskedelmi és Szolgáltató, KFT Osmotic device containing amantadine and an osmotic salt
AR053986A1 (es) 2004-12-03 2007-05-30 Osmotica Pharmaceutical Argent Dispositivo osmotico que contiene amantadina y una sal osmotica
US8574626B2 (en) 2004-12-03 2013-11-05 Osmotica Kereskedelmi és Szolgáltató KFT Osmotic device containing amantadine and an osmotic salt
EP1858492B1 (fr) * 2005-01-27 2008-11-12 ALZA Corporation Forme galenique osmotique orale comprenant une membrane a flux eleve
AP2274A (en) * 2005-01-28 2011-08-19 Euro Celtiques Sa Alcohol resistant dosage forms.
EP1695700A1 (fr) * 2005-02-28 2006-08-30 Euro-Celtique S.A. Forme posologique contenant de l'oxycodone et de la naloxone
EP1702558A1 (fr) 2005-02-28 2006-09-20 Euro-Celtique S.A. Procédé et dispositif pour évaluer la fonction de l'activité intestinale
US7919453B2 (en) * 2005-03-25 2011-04-05 Kimberly-Clark Worldwide, Inc. Dosage cap assembly for an applicator
US7993667B2 (en) * 2005-03-25 2011-08-09 Kimberly-Clark Worldwide, Inc. Methods of manufacturing a medicated tampon assembly
US7744556B2 (en) * 2005-03-25 2010-06-29 Kimberly-Clark Worldwide, Inc. Delivery tube assembly for an applicator
US7527614B2 (en) 2005-03-25 2009-05-05 Kimberly-Clark Worldwide, Inc. Protective tube for a medicated tampon
US9295289B2 (en) * 2005-04-01 2016-03-29 Leslie Jane James Waist-fastening, hip-encompassing apparel with at least one concealed storage compartment
BRPI0609636B8 (pt) 2005-04-08 2021-05-25 Abbott Lab formulação oral de liberação modificada que compreende um agente ativo e um revestimento entérico
US20080152714A1 (en) * 2005-04-08 2008-06-26 Yi Gao Pharmaceutical Formulations
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
JP2008536928A (ja) * 2005-04-19 2008-09-11 アルザ・コーポレーシヨン トラマドール及び、ガバペンチンを含んでなる物質、の組み合わせ物
US7708726B2 (en) * 2005-04-28 2010-05-04 Kimberly-Clark Worldwide, Inc. Dosage form cap for an applicator
NZ561375A (en) 2005-06-27 2011-06-30 Biovail Lab Int Srl Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound
KR20080030637A (ko) * 2005-06-29 2008-04-04 알자 코포레이션 삼투성 제형에 대하여 감소된 건조 시간을 제공하는반투과성 조성물
JP2009507774A (ja) * 2005-08-04 2009-02-26 アルザ・コーポレーシヨン 改良された性質を提供するポリマー混合物による半透過性膜を含んでなる浸透性用量形態物
US20070036929A1 (en) * 2005-08-09 2007-02-15 The Boeing Company Thin film applique
BRPI0615410A2 (pt) * 2005-08-30 2013-02-13 Nicholas Piramal India Ltd composiÇço farmacÊutica de liberaÇço prolongada de metformina e processo para produÇço da mesma
US20070212397A1 (en) * 2005-09-15 2007-09-13 Roth Daniel B Pharmaceutical delivery device and method for providing ocular treatment
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
JP5505760B2 (ja) 2005-09-27 2014-05-28 ティッシュテク・インコーポレーテッド 羊膜調製物及び精製組成物及びその使用方法
US20070190137A1 (en) * 2005-10-07 2007-08-16 Reyes Iran Osmotic dosage form with controlled release and fast release aspects
US20070092559A1 (en) * 2005-10-24 2007-04-26 Jinghua Yuan Liquid dosage forms having enteric properties of delayed and then sustained release
PL116330U1 (en) 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US8022054B2 (en) 2005-11-28 2011-09-20 Marinus Pharmaceuticals Liquid ganaxolone formulations and methods for the making and use thereof
US20070141118A1 (en) * 2005-12-15 2007-06-21 Damico Joyce A Layered dosage form for a medicated tampon assembly
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US20090022798A1 (en) * 2007-07-20 2009-01-22 Abbott Gmbh & Co. Kg Formulations of nonopioid and confined opioid analgesics
US20100172989A1 (en) * 2006-01-21 2010-07-08 Abbott Laboratories Abuse resistant melt extruded formulation having reduced alcohol interaction
US20090317355A1 (en) * 2006-01-21 2009-12-24 Abbott Gmbh & Co. Kg, Abuse resistant melt extruded formulation having reduced alcohol interaction
EP1813276A1 (fr) * 2006-01-27 2007-08-01 Euro-Celtique S.A. Formes de dosage inviolables
US20070196487A1 (en) * 2006-02-16 2007-08-23 Geerke Johan H Method and apparatus for drilling orifices in osmotic tablets incorporating near-infrared spectroscopy
CA2646023A1 (fr) 2006-03-10 2007-09-20 Neurogen Corporation Piperazinyl-oxoalkyl-tetrahydroisoquinoleines et analogues apparentes
EP2007360B1 (fr) * 2006-04-03 2014-11-26 Isa Odidi Dispositif d'administration à libération commandée comprenant un enrobage organosol
CN101453996B (zh) * 2006-04-03 2016-05-11 伊萨·奥迪迪 药物递送组合物
US8747897B2 (en) 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US20080090897A1 (en) 2006-08-11 2008-04-17 The Johns Hopkins University Compositions and methods for neuroprotectin
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
EP1897543A1 (fr) 2006-08-30 2008-03-12 Euro-Celtique S.A. Gaufre de buprénorphine pour la thérapie de substitution
KR101464424B1 (ko) 2006-09-22 2014-11-27 파마시클릭스, 인코포레이티드 브루톤 티로신 키나제 억제제
MX2009005478A (es) 2006-11-27 2009-08-12 Lundbeck & Co As H Derivados de heteroarilamida.
BRPI0717721A2 (pt) 2006-11-28 2013-10-29 Marinus Pharmaceuticals "partículas complexadas de drogas, composição farmacêutica, uso de uma composição farmacêutica, partículas complexadas de droga estabilizadas no tamanho, método para a preparação de partículas estabilizadas da droga, composição farmacêutica sólida, comprimido oral ingerível e composição líquida em nanopartículas estabilizadas no tamanho"
EP2119442A4 (fr) * 2006-12-28 2010-12-15 Astellas Pharma Inc Composition pharmaceutique à libération entretenue de tacrolimus
US8524749B2 (en) * 2007-02-09 2013-09-03 Alza Corporation Controlled release compositions of tizanidine
US8895061B2 (en) * 2007-03-02 2014-11-25 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
US20070172525A1 (en) * 2007-03-15 2007-07-26 Ramesh Sesha Anti-diabetic combinations
US20080064701A1 (en) * 2007-04-24 2008-03-13 Ramesh Sesha Anti-diabetic combinations
EP2124907B1 (fr) 2007-03-19 2018-05-30 Vita Sciences, Llc Timbre transdermique et méthode pour l'administration de vitamine b12
US20090082315A1 (en) * 2007-09-05 2009-03-26 Raif Tawakol Compositions and Methods for Controlling Cholesterol Levels
EP2200607A4 (fr) 2007-09-10 2012-02-22 Calcimedica Inc Composés modulant le calcium intracellulaire
US20090087484A1 (en) * 2007-09-28 2009-04-02 Alza Corporation Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
CN102908339A (zh) 2007-11-23 2013-02-06 格吕伦塔尔有限公司 他喷他多组合物
AU2008347158B8 (en) 2007-12-06 2013-08-22 Durect Corporation Oral pharmaceutical dosage forms
US9226907B2 (en) 2008-02-01 2016-01-05 Abbvie Inc. Extended release hydrocodone acetaminophen and related methods and uses thereof
US8551524B2 (en) * 2008-03-14 2013-10-08 Iycus, Llc Anti-diabetic combinations
WO2009137630A1 (fr) * 2008-05-07 2009-11-12 Wintherix Llc Procédés pour identifier des composés qui modulent la signalisation wnt dans des cellules cancéreuses
WO2009137631A2 (fr) * 2008-05-07 2009-11-12 Wintherix Llc Procédés d'identification de composés ayant une incidence sur l'expression d'isoformes de protéines associées au cancer
NZ588311A (en) * 2008-07-24 2012-08-31 Handa Pharmaceuticals Llc Stabilized atypical antipsychotic formulation to treat psychiatric conditions
BRPI0917719A2 (pt) 2008-08-27 2019-11-19 Calcimedica Inc compostos que modulam cálcio intracelular
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
EP2163240A1 (fr) 2008-09-12 2010-03-17 Universita' Degli Studi Di Genova Méthode pour la production des matrices compactes bioadhésives
JP6216489B2 (ja) 2008-10-30 2017-10-18 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 新規の、効力のあるタペンタドール剤形
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
WO2010071866A2 (fr) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Combinaison thérapeutique pour l'arthrite avec du tranilast
WO2010083035A2 (fr) 2009-01-14 2010-07-22 Corium International, Inc. Administration transdermique de tamsulosine
AU2010208046B2 (en) 2009-01-29 2014-10-02 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US20100209489A1 (en) * 2009-02-04 2010-08-19 Supernus Pharmaceuticals, Inc. Formulations of desvenlafaxine
WO2010099508A1 (fr) 2009-02-26 2010-09-02 Theraquest Biosciences, Inc. Compositions pharmaceutiques orales à libération prolongée de 3-hydroxy-n-méthylmorphinane et procédé d'utilisation
US9271940B2 (en) 2009-03-10 2016-03-01 Purdue Pharma L.P. Immediate release pharmaceutical compositions comprising oxycodone and naloxone
EP2421901B1 (fr) 2009-04-24 2015-10-28 Tissue Tech, Inc. Composition contenant le complexe hc ha et procédés d'utilisation de celle-ci
KR20140069381A (ko) 2009-06-02 2014-06-10 다우 글로벌 테크놀로지스 엘엘씨 서방출 투여형
US7718662B1 (en) 2009-10-12 2010-05-18 Pharmacyclics, Inc. Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US20110238036A1 (en) * 2009-12-23 2011-09-29 Psivida Us, Inc. Sustained release delivery devices
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
US9260417B2 (en) 2010-02-08 2016-02-16 Amitech Therapeutic Solutions, Inc. Therapeutic methods and compositions involving allosteric kinase inhibition
CN102884060B (zh) 2010-03-24 2019-07-19 阿米泰克治疗方案公司 用于抑制激酶的杂环化合物
US20120070465A1 (en) 2010-03-29 2012-03-22 Astellas Pharma Inc. Pharmaceutical composition for modified release
US11607407B2 (en) 2010-04-13 2023-03-21 Relmada Therapeutics, Inc. Dermal pharmaceutical compositions of 1-methyl-2′,6′-pipecoloxylidide and method of use
WO2011130689A1 (fr) 2010-04-15 2011-10-20 Tracon Pharmaceuticals, Inc. Potentialisation de l'activité anticancéreuse par polythérapie avec des inhibiteurs de la voie ber
AU2011248877B9 (en) 2010-04-27 2015-11-05 Calcimedica Inc. Compounds that modulate intracellular calcium
AU2011248579A1 (en) 2010-04-27 2012-11-29 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2011143152A2 (fr) 2010-05-11 2011-11-17 Questcor Pharmaceuticals Acth pour le traitement de la sclérose latérale amyotrophique
IL300955A (en) 2010-06-03 2023-04-01 Pharmacyclics Llc (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-H1-pyrazolo[4,3-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1- Indicated for use as a drug to treat chronic lymphocytic leukemia or small lymphocytic lymphoma
BR112013000190A2 (pt) 2010-07-06 2017-11-07 Gruenenthal Gmbh formas de dosagem de retenção gástrica compreendendo um análogo de gaba e um opioide
US20120015031A1 (en) 2010-07-14 2012-01-19 Grunenthal Gmbh Novel gastro-retentive dosage forms
AU2011285545B2 (en) 2010-08-05 2014-03-13 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
AU2011285501B2 (en) 2010-08-05 2014-02-27 Forsight Vision4, Inc. Implantable therapeutic device
EP2600876B1 (fr) 2010-08-05 2015-04-29 Forsight Vision4, Inc. Procédés et appareils d'administration combinée de médicament
WO2012027710A2 (fr) 2010-08-27 2012-03-01 Calcimedica Inc. Composés modulant le calcium intracellulaire
US8796416B1 (en) 2010-10-25 2014-08-05 Questcor Pharmaceuticals, Inc ACTH prophylactic treatment of renal disorders
CA2818612C (fr) 2010-11-19 2020-12-29 Forsight Vision4, Inc. Formulations d'agents therapeutiques pour des dispositifs implantes
PT2826467T (pt) 2010-12-22 2017-10-25 Purdue Pharma Lp Formas envolvidas de dosamento de libertação controlada resistentes à adulteração
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
WO2012094638A1 (fr) 2011-01-07 2012-07-12 Skinmedica, Inc. Compositions de modification de mélanine et procédés d'utilisation
WO2012149486A1 (fr) 2011-04-28 2012-11-01 Tissuetech, Inc. Procédés de modulation de remodélisation osseuse
WO2012170905A1 (fr) 2011-06-10 2012-12-13 Tissuetech, Inc. Procédés de traitement de tissus fœtaux de support, produits en poudre à base de tissu fœtal de support et leurs utilisations
WO2013003620A2 (fr) 2011-06-28 2013-01-03 Forsight Vision4, Inc. Procédés et appareil de diagnostic
LT2755600T (lt) 2011-09-16 2021-04-26 Forsight Vision4, Inc. Skysčio pakeitimo aparatas
US20130090633A1 (en) * 2011-10-07 2013-04-11 University Of Southern California Osmotic patch pump
CA2795586A1 (fr) 2011-11-15 2013-05-15 Golden Biotechnology Corporation Methodes et compositions pour le traitement, la modification et la gestion de la douleur attribuable au cancer des os
US8377946B1 (en) 2011-12-30 2013-02-19 Pharmacyclics, Inc. Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
US20130172424A1 (en) 2011-12-30 2013-07-04 Golden Biotechnology Corporation Methods and compositions for treating diabetes
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
SE1350211A1 (sv) 2012-02-23 2013-08-24 Golden Biotechnology Corp Metoder och kompositioner för behandling av cancermetastaser
BR112014023809A2 (pt) 2012-03-26 2017-07-18 Golden Biotechnology Corp métodos e composições para o tratamento de doenças vasculares ateroscleróticas
EP3838293A1 (fr) 2012-07-11 2021-06-23 Tissuetech, Inc. Compositions contenant des complexes hc-ah/ptx3 et procédés d'utilisation associés
US20150259355A1 (en) 2012-07-16 2015-09-17 Rhodes Technologies Process for improved opioid synthesis
JP6236447B2 (ja) 2012-07-16 2017-11-22 ローズ テクノロジーズ 改善されたオピオイド合成方法
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
BR112015011798A2 (pt) 2012-11-21 2017-07-11 Golden Biotechnology Corp métodos e composições para tratar doenças neurodegenerativas
JP6208261B2 (ja) 2013-02-05 2017-10-04 パーデュー、ファーマ、リミテッド、パートナーシップＰｕｒｄｕｅ Ｐｈａｒｍａ Ｌ．Ｐ． タンパリング抵抗性医薬製剤
TWI597061B (zh) 2013-02-20 2017-09-01 國鼎生物科技股份有限公司 治療白血病之方法及組成物
EP2968475A2 (fr) 2013-03-14 2016-01-20 Questcor Pharmaceuticals, Inc. Acth dans le traitement du syndrome de détresse respiratoire aiguë
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
EP2983468A4 (fr) 2013-03-15 2016-09-07 Durect Corp Compositions ayant un agent de modification rhéologique pour réduire une variabilité de dissolution
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
CN105246438B (zh) 2013-03-28 2018-01-26 弗赛特影像4股份有限公司 用于输送治疗物质的眼科植入物
KR20160003128A (ko) 2013-04-30 2016-01-08 애브비 인코포레이티드 아트라센탄을 사용하는 지질 프로파일을 개선시키기 위한 방법
MX2016000810A (es) 2013-07-23 2016-08-05 Euro Celtique Sa Combinacion de oxicodona y naloxona para su uso en el tratamiento de dolor en pacientes que sufren de dolor y una enfermedad que resulta la disbiosis intestinal y/o aumento del riesgo de la translocacion bacteriana intestinal.
EP3782614A1 (fr) 2013-10-07 2021-02-24 Impax Laboratories, LLC Formulations mucoadhésives à libération contrôlée de lévodopa et/ou d'esters de lévodopa et leurs utilisations
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US9611263B2 (en) 2013-10-08 2017-04-04 Calcimedica, Inc. Compounds that modulate intracellular calcium
KR20160093675A (ko) 2013-12-05 2016-08-08 파마싸이클릭스 엘엘씨 브루톤 티로신 키나제의 억제제
JP6244035B2 (ja) 2014-01-15 2017-12-06 ローズ テクノロジーズ 改良されたオキシモルホン合成のための方法
CN106029670A (zh) 2014-01-15 2016-10-12 罗德科技公司 改进的羟考酮合成的方法
ES2762806T3 (es) 2014-02-10 2020-05-25 Respivant Sciences Gmbh Tratamiento utilizando estabilizadores de mastocitos para trastornos sistémicos
AU2015213681B2 (en) 2014-02-10 2020-03-12 Respivant Sciences Gmbh Mast cell stabilizers for lung disease treatment
WO2015164213A1 (fr) 2014-04-23 2015-10-29 The Research Foundation For The State University Of New York Réaction de ligature bio-orthogonale rapide et efficace et hétérocycles contenant du bore utiles en association avec celle-ci
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
ES2803102T3 (es) 2014-07-15 2021-01-22 Forsight Vision4 Inc Dispositivo de administración de implante ocular
JP2017524034A (ja) 2014-08-08 2017-08-24 フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法
US9839644B2 (en) 2014-09-09 2017-12-12 ARKAY Therapeutics, LLC Formulations and methods for treatment of metabolic syndrome
CN107249515B (zh) 2014-11-10 2019-10-01 弗赛特影像4股份有限公司 可膨胀药物递送装置和使用方法
US9359316B1 (en) 2014-11-25 2016-06-07 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
US10227333B2 (en) 2015-02-11 2019-03-12 Curtana Pharmaceuticals, Inc. Inhibition of OLIG2 activity
WO2016132218A1 (fr) 2015-02-20 2016-08-25 Osmotica Kereskedelmi Es Szolgaltato Kft Méthode d'administration de r-baclofène dans une forme pharmaceutique à libération prolongée
TW201642914A (zh) 2015-02-23 2016-12-16 組織科技股份有限公司 用於治療眼部疾病及失調的裝置及方法
MX2017011018A (es) 2015-02-27 2018-01-18 Curtana Pharmaceuticals Inc Inhibicion de la actividad de olig2.
EP3061501A1 (fr) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition pour le traitement de l'acné
JP2018516869A (ja) 2015-05-20 2018-06-28 ティッシュテック，インク． 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法
EP3117825A1 (fr) 2015-07-16 2017-01-18 Rottapharm S.p.A. Formulation orale comprenant de la berbérine et un extrait de morus alba
EP3331522A1 (fr) 2015-08-07 2018-06-13 Patara Pharma LLC Méthodes de traitement de troubles liés aux mastocytes par des stabilisateurs de mastocytes
US10265296B2 (en) 2015-08-07 2019-04-23 Respivant Sciences Gmbh Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
WO2017040617A1 (fr) 2015-08-31 2017-03-09 Pharmacyclics Llc Combinaisons d'inhibiteurs de btk pour le traitement du myélome multiple
CN113069681B (zh) 2015-11-20 2022-12-23 弗赛特影像4股份有限公司 制造用于缓释药物递送的治疗装置的方法
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US10851123B2 (en) 2016-02-23 2020-12-01 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
EP3799844B1 (fr) 2016-04-05 2023-10-04 ForSight Vision4, Inc. Dispositifs implantables d'administration de médicaments par voie oculaire
US11883381B2 (en) 2016-05-12 2024-01-30 The Regents Of The University Of Michigan ASH1L inhibitors and methods of treatment therewith
US10821105B2 (en) 2016-05-25 2020-11-03 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists in combination with local anesthetics and vasoconstrictors for improved local anesthesia
WO2017205766A1 (fr) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibiteurs de la kinase associée au récepteur de l'interleukine-1
WO2017205769A1 (fr) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibiteurs de la kinase associée au récepteur de l'interleukine 1
WO2017205762A1 (fr) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibiteurs de la kinase associée au récepteur de l'interleukine 1
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
CN106317468A (zh) * 2016-08-23 2017-01-11 无锡市永亿精密铸造有限公司 一种用于超声波美容仪的复合材料
CA3035123A1 (fr) 2016-08-26 2018-03-01 Curtana Pharmaceuticals, Inc. Inhibition de l'activite d'olig2
CN110139646A (zh) 2016-08-31 2019-08-16 瑞思皮万特科学有限责任公司 用于治疗由特发性肺纤维化引起的慢性咳嗽的色甘酸组合物
US10736905B1 (en) 2016-09-09 2020-08-11 Shahin Fatholahi Nefopam dosage forms and methods of treatment
EP3522983A4 (fr) 2016-10-07 2020-06-03 Respivant Sciences GmbH Compositions à base de cromolyne pour le traitement d'une fibrose pulmonaire
US10736874B1 (en) 2017-09-08 2020-08-11 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
US11446311B2 (en) 2017-09-08 2022-09-20 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
CN111542318A (zh) 2017-11-10 2020-08-14 密歇根大学董事会 Ash1l降解剂及用其进行治疗的方法
CN111655206B (zh) 2017-11-21 2022-10-14 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法
CN112040947A (zh) 2017-12-07 2020-12-04 密歇根大学董事会 Nsd家族抑制剂及用其进行治疗的方法
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
MX2020008527A (es) 2018-02-16 2020-09-18 Esperion Therapeutics Inc Formulaciones de liberacion sostenida de acido bempedoico.
US11685722B2 (en) 2018-02-28 2023-06-27 Curtana Pharmaceuticals, Inc. Inhibition of Olig2 activity
CN112533581B (zh) 2018-06-07 2024-08-30 密歇根大学董事会 Prc1抑制剂及用其进行治疗的方法
TW202019887A (zh) 2018-07-27 2020-06-01 美商同心止痛劑股份有限公司 酚系trpv1促效劑之聚乙二醇化前藥
WO2020142557A1 (fr) 2018-12-31 2020-07-09 Biomea Fusion, Llc Inhibiteurs irréversibles de l'interaction ménine-mll
BR112021018254A2 (pt) 2019-03-15 2022-03-15 Unicycive Therapeutics Inc Derivados de nicorandil
AU2021266767B2 (en) 2020-05-08 2024-10-24 Golden Biotechnology Corporation Methods and compositions for treating an RNA virus induced disease
JP2023533982A (ja) 2020-07-10 2023-08-07 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｇａｓ４１阻害剤及びその使用方法
CA3202151A1 (fr) 2020-12-16 2022-06-23 Biomea Fusion, Inc. Composes de pyrimidine fusionnee utilises comme inhibiteurs de l'interaction menine-mll
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen
WO2022140448A1 (fr) 2020-12-22 2022-06-30 Amneal Pharmaceuticals Llc Schéma posologique de lévodopa
EP4384179A1 (fr) 2021-08-11 2024-06-19 Biomea Fusion, Inc. Inhibiteurs covalents de l'interaction ménine-mll pour le diabète sucré
WO2023027966A1 (fr) 2021-08-24 2023-03-02 Biomea Fusion, Inc. Composés de pyrazine en tant qu'inhibiteurs irréversibles de flt3
WO2023039240A1 (fr) 2021-09-13 2023-03-16 Biomea Fusion, Inc. Inhibitors irréversibles de kras
WO2023086341A1 (fr) 2021-11-09 2023-05-19 Biomea Fusion, Inc. Inhibiteurs de kras
WO2023119230A1 (fr) 2021-12-22 2023-06-29 L'oreal Compositions de modulation de la voie de coagulation et de la voie de nicotinamide-adénine dinucléotide et leurs procédés d'utilisation
EP4370506A1 (fr) 2021-12-30 2024-05-22 Biomea Fusion, Inc. Composés pyrazines utilisés comme inhibiteurs de flt3
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
WO2023235618A1 (fr) 2022-06-03 2023-12-07 Biomea Fusion, Inc. Composés de pyrimidine fusionnés en tant qu'inhibiteurs de la ménine
US20250002458A1 (en) 2023-05-24 2025-01-02 Unicycive Therapeutics Inc. Salt forms of nicorandil derivative
WO2024249950A1 (fr) 2023-06-02 2024-12-05 Biomea Fusion, Inc. Composés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de la ménine

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3129159A (en) * 1961-09-29 1964-04-14 Membranfiltergesellschaft G M Process for manufacturing membranes
US3497072A (en) * 1966-05-02 1970-02-24 Aerojet General Co Reverse osmosis membrane and method of manufacture
US3460683A (en) * 1966-08-22 1969-08-12 Aerojet General Co Cellulose acetate membranes
US3567809A (en) * 1966-10-07 1971-03-02 Fuji Photo Film Co Ltd Method of varying the pore diameters of fine pores in cellulose acetate film
US3522335A (en) * 1968-02-29 1970-07-28 Eastman Kodak Co Methods for producing reverse osmosis membrane and the composition utilized
US3607329A (en) * 1969-04-22 1971-09-21 Us Interior Cellulose acetate butyrate semipermeable membranes and their production
US3593855A (en) * 1969-05-13 1971-07-20 Westinghouse Electric Corp High flow porous reverse osmosis membranes containing lipids
US3646179A (en) * 1969-05-22 1972-02-29 Westinghouse Electric Corp Process for preparing high pressure cellulose acetate semipermeable membranes
US3592671A (en) * 1969-12-22 1971-07-13 Eastman Kodak Co Stabilization of cellulose ester dopes
US3592672A (en) * 1969-12-22 1971-07-13 Eastman Kodak Co Dry stabilized,rewettable semipermeable cellulose ester and ether membranes and their preparation
US3760806A (en) * 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
SE352811B (fr) * 1971-06-04 1973-01-15 Pharmacia Ab
US3772072A (en) * 1971-06-14 1973-11-13 Eastman Kodak Co Method for treating reverse osmosis membranes
US3721623A (en) * 1971-07-23 1973-03-20 Westinghouse Electric Corp Method of improving the salt rejection of semipermeable reverse osmosis membranes
US3938515A (en) * 1971-12-20 1976-02-17 Alza Corporation Novel drug permeable wall
GB1388034A (en) * 1972-04-12 1975-03-19 Atomic Energy Authority Uk Membranes for reverse osmosis
US3878276A (en) * 1972-05-24 1975-04-15 Us Interior Cellulose acetate blend membranes
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3929132A (en) * 1973-04-10 1975-12-30 Alza Corp Osmotic dispenser
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls

Also Published As

Publication number Publication date
SE430301B (sv) 1983-11-07
IL50851A (en) 1979-11-30
NL187298C (nl) 1991-08-16
DE2653232C2 (fr) 1989-08-24
JPS5264419A (en) 1977-05-27
JPS6058724B2 (ja) 1985-12-21
ES453530A1 (es) 1977-12-01
GB1528265A (en) 1978-10-11
AU1980276A (en) 1978-05-25
MX157537A (es) 1988-11-29
NL187298B (nl) 1991-03-18
AT356821B (de) 1980-05-27
DK150533C (da) 1987-10-12
CH629957A5 (de) 1982-05-28
AR216642A1 (es) 1980-01-15
IE44264L (en) 1977-05-24
NL7613110A (nl) 1977-05-26
SE7613035L (sv) 1977-05-25
IE44264B1 (en) 1981-09-23
FR2332008A1 (fr) 1977-06-17
AU506506B2 (en) 1980-01-10
IL50851A0 (en) 1977-01-31
US4160020A (en) 1979-07-03
ATA854676A (de) 1979-10-15
ZA766900B (en) 1977-10-26
IT1070481B (it) 1985-03-29
US4077407A (en) 1978-03-07
FR2332008B1 (fr) 1979-03-09
DK150533B (da) 1987-03-23
CA1074653A (fr) 1980-04-01
DK519276A (da) 1977-05-25
DE2653232A1 (de) 1977-06-08

Similar Documents

Publication Publication Date Title
BE848639A (fr) Dispositif permettant de liberer des substances par osmose dans un milieu liquide,
BE861031A (fr) Dispositif agissant par osmose pour liberer des substances dans un milieu liquide
FR2342764A1 (fr) Dispositif agissant par osmose, pour liberer des substances dans un milieu aqueux.
FR2329321A1 (fr) Dispositif de purification de liquide
NL182862C (nl) Inrichting voor waterontzilting door omgekeerde osmose.
MX147348A (es) Mejoras a dispositivo de orificio para un sistema transportador de liquidos
AR197512A1 (es) Dispositivo de ultrafiltracion para extraer un vehiculo liquido de una muestra que contiene el vehiculo
FR2340758A1 (fr) Dispositif pour la diffusion de substances entre deux fluides a travers des membranes semi-permeables
BE853963A (fr) Dispositif pour la diffusion de substances entre deux fluides au moyen de membranes semi-permeables
CH558028A (de) Vorrichtung zum verschweissen der beiden teile eines diapositiv-rahmens.
FR2306103A1 (fr) Dispositif actionne par la clarte exterieure, pour vehicules
BE812579A (fr) Dispositif pour la diffusion de substances entre deux fluides a travers des membranes semi-permeables
FR2329359A1 (fr) Dispositif distributeur de liquide a manoeuvre manuelle
FR2323426A1 (fr) Dispositif pour la diffusion de substances entre deux fluides au moyen de membranes semi-permeables
ES196798Y (es) Un aparato perfeccionado para la filtracion de liquidos.
BE820298A (fr) Dispositif antiblocage pour frein actionne par pression fluidique
SE389273B (sv) Sprinkleranordning, foretredesvis avsedd for vatten
FR2323425A1 (fr) Dispositif pour la diffusion de substances entre deux fluides au moyen de membranes semi-permeables
DK136770C (da) Sulfonyloxyphenylurinstoffer til anvendelse i herbicider
BE797249A (fr) Dispositif de couplage pour multiplexage par repartition dans le temps
ES197456Y (es) Cuba perfeccionada para separar los componentes suspendidosde una suspension liquida.
BE802970A (fr) Dispositif pour entrainer le peigne, tournant par intermittence de metiers a tisser
BE799713A (fr) Dispositif pour la regeneration du charbon actif,
DK138617B (da) Anordning til måling af væskeniveau.
FR2327953A1 (fr) Dispositif de freinage pour treuils, de preference dans les systemes de remorquage pour cibles aeriennes

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ALZA CORP.

Effective date: 19961123