BE847234A - Nouveaux composes pour combattre les leucemies et les tumeurs malignes, - Google Patents

Nouveaux composes pour combattre les leucemies et les tumeurs malignes,

Info

Publication number: BE847234A
Authority: BE; Belgium
Prior art keywords: fight; leukemia; new compounds; malignant tumors; malignant
Prior art date: 1975-10-16

Application number

BE171474A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-16

Filing date

1976-10-13

Publication date

1977-04-13

1976-10-13 Application filed filed Critical

1977-04-13 Publication of BE847234A publication Critical patent/BE847234A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

BE171474A 1975-10-16 1976-10-13 Nouveaux composes pour combattre les leucemies et les tumeurs malignes, BE847234A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB42509/75A GB1561290A (en)	1975-10-16	1975-10-16	Pyrimid - 2 - ones

Publications (1)

Publication Number	Publication Date
BE847234A true BE847234A (fr)	1977-04-13

Family

ID=10424751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE171474A BE847234A (fr)	1975-10-16	1976-10-13	Nouveaux composes pour combattre les leucemies et les tumeurs malignes,

Country Status (14)

Country	Link
US (1)	US4395406A (fr)
JP (1)	JPS5253869A (fr)
BE (1)	BE847234A (fr)
CA (1)	CA1086736A (fr)
CH (3)	CH634308A5 (fr)
DE (1)	DE2646676A1 (fr)
DK (1)	DK144525C (fr)
FR (1)	FR2327765A1 (fr)
GB (1)	GB1561290A (fr)
IE (1)	IE44431B1 (fr)
LU (1)	LU75994A1 (fr)
NL (1)	NL7611415A (fr)
NO (1)	NO151040C (fr)
SE (1)	SE439305B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1582884A (en) *	1977-05-19	1981-01-14	Beecham Group Ltd	Clavulanic acid derivatives their preparation and use
DK330880A (da) *	1979-08-03	1981-02-04	Beecham Group Ltd	Fremgangsmaade til fremstilling af clavulansyrederivater
ES8205399A1 (es) *	1980-01-07	1982-06-01	Nyegaard & Co As	Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
NZ195992A (en) *	1980-01-10	1983-11-30	Nyegaard & Co As	5-halopyrimidines;their 2-sulphides and s-oxides;pharmaceutical compositions
CA1160226A (fr) *	1980-07-15	1984-01-10	Gordon H. Phillipps	Pyrimidine-2-ones substituees, leurs sels, procedes de preparation, composes pharmaceutiques les contenant et methodes
CA1159830A (fr) *	1980-07-15	1984-01-03	Gordon H. Phillipps	Pyrimidine-2-ones substituees, leurs sels, procedes de preparation, composes pharmaceutiques les contenant et methode
EP0053893B1 (fr) *	1980-12-09	1985-03-20	Beecham Group Plc	Dérivés de l'acide clavulanique, leur préparation et leur application
US4562182A (en) *	1980-12-23	1985-12-31	Beecham Group P.L.C.	Compounds containing beta-lactams
JPS57136575A (en) *	1981-01-09	1982-08-23	Nyegaard & Co As	Substituted pyrimidine-2-one compound
DK404982A (da) *	1981-09-11	1983-03-12	Nyegaard & Co As	Fremgangsmaade til fremstilling af substituerede pyrimid-2-oner eller salte deraf
US4782142A (en) *	1982-01-05	1988-11-01	The Research Foundation Of State University Of New York	Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
DK83783A (da) *	1982-02-24	1983-08-25	Nyegaard & Co As	Fremgangsmaade til fremstilling af substituerede pyrimidin-2-oner
CA1275410C (fr) *	1986-03-14	1990-10-23	Karnail S. Atwal	Acides 1,2,3,4-tetrahydro-6-(substituant)-4-aryl (ou heterocyclo)-3-(substituant)-2-thioxo(ou oxo)-5-pyrimidinecarboxyliques et esters de ceux-ci
GB8706176D0 (en) *	1987-03-16	1987-04-23	Wellcome Found	Therapeutic nucleosides
US5252576A (en) *	1988-07-18	1993-10-12	Yamasa Shoyu Kabushiki Kaisha	1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient
GB9026114D0 (en) *	1990-11-30	1991-01-16	Norsk Hydro As	New compounds
WO1997014709A1 (fr) *	1995-10-13	1997-04-24	F. Hoffmann-La Roche Ag	Oligomeres antisens
NZ330360A (en) *	1997-06-02	1999-03-29	Hoffmann La Roche	5'-deoxy-cytidine derivatives, their manufacture and use as antitumoral agents
EP0882734B1 (fr) *	1997-06-02	2009-08-26	F. Hoffmann-La Roche Ag	Dérivés de 5'-déoxy-cytidine
US6005098A (en) *	1998-02-06	1999-12-21	Hoffmann-La Roche Inc.	5'deoxycytidine derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3317532A (en) *	1964-11-19	1967-05-02	Hoffmann La Roche	Derivatives of pyrimidine
DE2032559A1 (de) *	1970-06-27	1972-01-13	Schering Ag Berlin Und Bergkamen, 1000 Berlin	N-Substituierte Amide und Lactame
US3833586A (en) *	1971-03-25	1974-09-03	Morton Norwich Products Inc	1-(substituted benzyl)-2-(1h)pyrimidones and 1-(substituted benzyl)tetrahydro-2-(1h)pyrimidones
DE2440677A1 (de) *	1974-08-24	1976-03-04	Bayer Ag	Pyrimidinylthionophosphonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
DE2450951A1 (de) *	1974-10-26	1976-05-06	Bayer Ag	Pyrimidinyl(thiono)(thiol)phosphor (phosphon)-saeureester bzw. -esteramide, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
US4003900A (en) *	1976-03-11	1977-01-18	Morton-Norwich Products, Inc.	1-Benzyl-5-chloro-2-(1H)-pyrimidone

1975
- 1975-10-16 GB GB42509/75A patent/GB1561290A/en not_active Expired
1976
- 1976-10-13 BE BE171474A patent/BE847234A/fr not_active IP Right Cessation
- 1976-10-14 LU LU75994A patent/LU75994A1/xx unknown
- 1976-10-14 FR FR7630923A patent/FR2327765A1/fr active Granted
- 1976-10-14 DK DK462376A patent/DK144525C/da not_active IP Right Cessation
- 1976-10-15 SE SE7611493A patent/SE439305B/xx not_active IP Right Cessation
- 1976-10-15 DE DE19762646676 patent/DE2646676A1/de active Granted
- 1976-10-15 NL NL7611415A patent/NL7611415A/xx not_active Application Discontinuation
- 1976-10-15 CA CA263,452A patent/CA1086736A/fr not_active Expired
- 1976-10-15 IE IE2284/76A patent/IE44431B1/en unknown
- 1976-10-15 JP JP51123013A patent/JPS5253869A/ja active Pending
- 1976-10-15 NO NO763533A patent/NO151040C/no unknown
- 1976-10-15 CH CH1310376A patent/CH634308A5/de not_active IP Right Cessation
1980
- 1980-07-07 US US06/166,600 patent/US4395406A/en not_active Expired - Lifetime
1981
- 1981-06-18 CH CH405481A patent/CH634309A5/de not_active IP Right Cessation
- 1981-06-18 CH CH405581A patent/CH634310A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA1086736A (fr)	1980-09-30
FR2327765B1 (fr)	1981-11-20
CH634308A5 (de)	1983-01-31
NL7611415A (nl)	1977-04-19
FR2327765A1 (fr)	1977-05-13
GB1561290A (en)	1980-02-20
DK462376A (da)	1977-04-17
NO151040C (no)	1985-01-30
NO151040B (no)	1984-10-22
DE2646676C2 (fr)	1987-06-19
DK144525C (da)	1982-10-18
DE2646676A1 (de)	1977-04-28
SE439305B (sv)	1985-06-10
IE44431L (en)	1977-04-16
NO763533L (fr)	1977-04-19
JPS5253869A (en)	1977-04-30
CH634310A5 (de)	1983-01-31
IE44431B1 (en)	1981-12-02
CH634309A5 (de)	1983-01-31
LU75994A1 (fr)	1977-05-11
DK144525B (da)	1982-03-22
SE7611493L (sv)	1977-04-17
US4395406A (en)	1983-07-26

Publication	Publication Date	Title
BE847234A (fr)	1977-04-13	Nouveaux composes pour combattre les leucemies et les tumeurs malignes,
FR2300076A1 (fr)	1976-09-03	Nouveaux
FR2300081A1 (fr)	1976-09-03	Nouveaux d
FI66893B (fi)	1984-08-31	Saosom faergaemnen anvaendbara biskatjoniska azofoereningar forfarande foer deras framstaellning och deras anvaendning
BE835325A (fr)	1976-05-06	Nouveaux composes heterocycliques, leur preparation et compositions qui les contiennent
FR2300551A2 (fr)	1976-09-10	Nouveaux
FR2300077A1 (fr)	1976-09-03	Nouveaux ethers
FR2326420A1 (fr)	1977-04-29	Nouveaux composes heterocycliques et leur preparation
ATA289275A (de)	1977-08-15	Stranggiesspulver
FR2313883A1 (fr)	1977-01-07	Verrou pour fermoir
SE7504049L (sv)	1976-10-10	Colonpreparation
GB1539457A (en)	1979-01-31	Preparation of d-mannitol
FR2325377A1 (fr)	1977-04-22	Nouveaux n-aryl-n- (1-l-4-piperidinyl)-arylacetamides
FI55018B (fi)	1979-01-31	Hoeljeaemne saerskilt foer aerosolfoerpackningar och anordning foer aemnets framstaellning medelst kallpressning
SE7512782L (sv)	1976-10-01	Forbettrad urokinasframstellning
FR2298330A2 (fr)	1976-08-20	Nouveaux d
SE426166B (sv)	1982-12-13	Fortjockad och tverbunden vattenhaltig skumsprengemneskomposition
FR2338262A1 (fr)	1977-08-12	Nouveaux deri
FR2335252A1 (fr)	1977-07-15	Repose-pied pour skieur
FR2319358A1 (fr)	1977-02-25	Nouveaux homophtalimides
SE389807B (sv)	1976-11-22	Skidstavpar
BE837450A (fr)	1976-07-09	Nouveaux composes organometalliques
BE837950A (fr)	1976-07-27	Nouveaux composes polycliques psychotropes
SE432424B (sv)	1984-04-02	Halogenerade alkoxisilanforeningar och forfarande for deras framstellning
AT330625B (de)	1976-07-12	Langlaufski

Legal Events

Date	Code	Title	Description
1988-04-30	RE	Patent lapsed	Owner name: NYEGAARD & CO. A/S Effective date: 19871031

Date

Code

Title

Description

1988-04-30

Patent lapsed

Owner name: NYEGAARD & CO. A/S

Effective date: 19871031