BE826978A - Procede de preparation des adriamycines et nouveaux produits obtenus - Google Patents

Procede de preparation des adriamycines et nouveaux produits obtenus

Info

Publication number: BE826978A
Authority: BE; Belgium
Prior art keywords: adriamycins; preparing; products obtained; new products; new
Prior art date: 1974-03-22

Application number

BE154581A

Other languages

English (en)

French (fr)

Inventor

F Arcamone

A Di Marco

S Penco

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-03-22

Filing date

1975-03-21

Publication date

1975-09-22

1975-03-21 Application filed filed Critical

1975-09-22 Publication of BE826978A publication Critical patent/BE826978A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

BE154581A 1974-03-22 1975-03-21 Procede de preparation des adriamycines et nouveaux produits obtenus BE826978A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB1278374A GB1457632A (en)	1974-03-22	1974-03-22	Adriamycins

Publications (1)

Publication Number	Publication Date
BE826978A true BE826978A (fr)	1975-09-22

Family

ID=10011048

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE154581A BE826978A (fr)	1974-03-22	1975-03-21	Procede de preparation des adriamycines et nouveaux produits obtenus

Country Status (18)

Country	Link
US (1)	US4058519A (de)
JP (1)	JPS5840555B2 (de)
AT (1)	AT338420B (de)
AU (1)	AU497500B2 (de)
BE (1)	BE826978A (de)
CA (1)	CA1046507A (de)
CH (1)	CH612947A5 (de)
DE (1)	DE2510866C3 (de)
DK (1)	DK153158C (de)
ES (1)	ES435833A1 (de)
FR (1)	FR2264555B1 (de)
GB (1)	GB1457632A (de)
HK (1)	HK882A (de)
MY (1)	MY103912A (de)
NL (1)	NL176635C (de)
SE (1)	SE434844B (de)
SU (1)	SU583763A3 (de)
ZA (1)	ZA751781B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4133877A (en) *	1976-07-08	1979-01-09	Societa Farmaceutici Italia S.P.A.	Anthracycline ethers and use therefor
US4201773A (en) *	1978-07-26	1980-05-06	The United States Of America As Represented By The Department Of Health, Education And Welfare	7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4345068A (en) *	1979-11-22	1982-08-17	Farmitalia Carlo Erba S.P.A.	Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
DE3164763D1 (en) *	1980-11-01	1984-08-16	Erba Farmitalia	Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
DE51279T1 (de) *	1980-11-01	1983-05-26	Farmitalia Carlo Erba S.p.A., 20159 Milano	Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.
US4562177A (en) *	1982-08-17	1985-12-31	The Ohio State University Research Foundation	3'-Amino-2' halo-anthracycline antibiotics
US4537882A (en) *	1984-05-10	1985-08-27	Ohio State University	4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
DE3500029A1 (de) *	1985-01-02	1986-09-04	Farmitalia Carlo Erba S.p.A., Mailand/Milano	Anthracyclinester
GB2169284A (en) *	1985-01-05	1986-07-09	Erba Farmitalia	4'-Epidoxorubicin-14-esters
JPS61172891A (ja) *	1985-01-24	1986-08-04	フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ	アントラサイクリン類エステルの製法
US5124317A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.R.L.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) *	1985-08-02	1999-11-02	Pharmacia & Upjohn Company	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB8519452D0 (en) *	1985-08-02	1985-09-11	Erba Farmitalia	Injectable solutions
JPH034367Y2 (de) *	1986-05-20	1991-02-05
PT848009E (pt)	1996-12-16	2000-11-30	Pharmachemie Bv	Processo para a preparacao de epirubicina ou seus sais de adicao de acido a partir de daunorubicina
CN1188424C (zh) *	1998-10-16	2005-02-09	美露香株式会社	盐酸阿霉素的结晶
KR100850408B1 (ko) *	2000-08-10	2008-08-04	동아제약주식회사	안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
KR100785966B1 (ko) *	2000-08-10	2007-12-14	동아제약주식회사	안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
JP5475234B2 (ja)	2005-01-21	2014-04-16	アステックス・セラピューティクス・リミテッド	医薬化合物
PL375008A1 (pl)	2005-05-12	2006-11-13	Institut National De La Sante Et De La Recherche Medicale, Inserm	Nowe zastosowanie medyczne chlorowodorku epirubicyny
EP2073803B1 (de)	2006-10-12	2018-09-19	Astex Therapeutics Limited	Pharmazeutische kombinationen
US8883790B2 (en)	2006-10-12	2014-11-11	Astex Therapeutics Limited	Pharmaceutical combinations
US8173621B2 (en)	2008-06-11	2012-05-08	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
SG194404A1 (en)	2008-12-23	2013-11-29	Gilead Pharmasset Llc	Synthesis of purine nucleosides
AU2009329917B2 (en)	2008-12-23	2016-03-31	Gilead Pharmasset Llc	Nucleoside analogs
AR074897A1 (es)	2008-12-23	2011-02-23	Pharmasset Inc	Fosforamidatos de nucleosidos
PT2609923T (pt)	2010-03-31	2017-08-30	Gilead Pharmasset Llc	Processo para a cristalização de 2-(((s)- (perfluorofenoxi)(fenoxi)fosforil)amino)propanoato de (s)-isopropilo
CN108473523B (zh) *	2016-01-11	2022-03-15	浙江海正药业股份有限公司	一种盐酸表柔比星的制备方法及其中间体
SG10201913331VA (en)	2016-03-15	2020-03-30	Oryzon Genomics Sa	Combinations of lsd1 inhibitors for use in the treatment of solid tumors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3356674A (en) *	1961-07-07	1967-12-05	Rikagaku Kenkyusho	3-c-hydroxymethyl-3, 5-didesoxy-l-lyxofuranose and its derivatives, and a process for the production thereof
US3427300A (en) *	1965-11-12	1969-02-11	Merck & Co Inc	Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) *	1968-04-12	1974-04-09	Farmaceutici It Soc	Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) *	1968-05-23	1971-12-21	Biorex Laboratories Ltd	Derivatives of glycyrrhetinic acid
US3651090A (en) *	1969-12-17	1972-03-21	Cutter Lab	1 3-dioxolan-4-yl-alkyl guanidines
FR2183710A1 (en) *	1972-05-06	1973-12-21	Farmaceutici Italia	Daunomycin (hydrochloride) prepn - by reaction of daunomycinone with daunosamines, useful as antitumour agent and anti-leucemic

1974
- 1974-03-22 GB GB1278374A patent/GB1457632A/en not_active Expired
1975
- 1975-03-12 NL NLAANVRAGE7502934,A patent/NL176635C/xx not_active IP Right Cessation
- 1975-03-13 DE DE2510866A patent/DE2510866C3/de not_active Expired
- 1975-03-18 AT AT207475A patent/AT338420B/de not_active IP Right Cessation
- 1975-03-19 US US05/560,104 patent/US4058519A/en not_active Expired - Lifetime
- 1975-03-19 AU AU79263/75A patent/AU497500B2/en not_active Expired
- 1975-03-19 FR FR7508548A patent/FR2264555B1/fr not_active Expired
- 1975-03-20 ZA ZA00751781A patent/ZA751781B/xx unknown
- 1975-03-20 DK DK114475A patent/DK153158C/da not_active IP Right Cessation
- 1975-03-20 JP JP50033095A patent/JPS5840555B2/ja not_active Expired
- 1975-03-20 SE SE7503215A patent/SE434844B/xx active Protection Beyond IP Right Term
- 1975-03-20 CA CA222,609A patent/CA1046507A/en not_active Expired
- 1975-03-21 BE BE154581A patent/BE826978A/xx not_active IP Right Cessation
- 1975-03-21 CH CH365975A patent/CH612947A5/xx not_active IP Right Cessation
- 1975-03-21 SU SU7502115054A patent/SU583763A3/ru active
- 1975-03-21 ES ES435833A patent/ES435833A1/es not_active Expired
1982
- 1982-01-14 HK HK8/82A patent/HK882A/xx unknown
1988
- 1988-09-14 MY MYPI88001026A patent/MY103912A/en unknown

Also Published As

Publication number	Publication date
AU497500B2 (en)	1978-12-14
NL7502934A (nl)	1975-09-24
SE7503215L (de)	1975-09-23
JPS5840555B2 (ja)	1983-09-06
NL176635B (nl)	1984-12-17
FR2264555A1 (de)	1975-10-17
NL176635C (nl)	1985-05-17
DK153158B (da)	1988-06-20
DK114475A (de)	1975-09-23
CH612947A5 (de)	1979-08-31
SU583763A3 (ru)	1977-12-05
DE2510866B2 (de)	1979-12-06
CA1046507A (en)	1979-01-16
HK882A (en)	1982-01-22
JPS50126656A (de)	1975-10-04
AU7926375A (en)	1976-09-23
GB1457632A (en)	1976-12-08
DE2510866C3 (de)	1980-08-14
MY103912A (en)	1993-10-30
AT338420B (de)	1977-08-25
US4058519A (en)	1977-11-15
DE2510866A1 (de)	1975-10-02
ATA207475A (de)	1976-12-15
ZA751781B (en)	1976-02-25
ES435833A1 (es)	1976-12-01
DK153158C (da)	1989-01-16
SE434844B (sv)	1984-08-20
FR2264555B1 (de)	1980-01-11

Publication	Publication Date	Title
BE826978A (fr)	1975-09-22	Procede de preparation des adriamycines et nouveaux produits obtenus
FR2275462A1 (fr)	1976-01-16	Procede de preparation de composes de bipyridilium et produits obtenus
BE872210A (fr)	1979-05-22	Procede de preparation de nitrodiarylamines et nouveaux produits ainsi obtenus
FR2279720A1 (fr)	1976-02-20	Procede de preparation d'alkyltetracyclines et nouveaux produits obtenus
FR2276337A1 (fr)	1976-01-23	Procede de preparation de terpolymeres lactame-polyol-polyacyllactame ou acylpolylactame et nouveaux produits ainsi obtenus
FR2274280A1 (fr)	1976-01-09	Procede de pastillage direct de la phenacetine et produits obtenus
FR2274299A1 (fr)	1976-01-09	Procede de preparation de 7b-acylamino-7a-alcoxycephalosporines et 6b-acylamino-6a-alcoxy-penicillines, nouveaux produits obtenus et leur application
BE828409A (fr)	1975-10-27	Procede en continu pour la preparation de polymelanges du type abs et nouveaux produits ainsi obtenus
BE832664A (fr)	1976-02-23	Procede perfectionne de preparation de cyanoghanidines et produits obtenus
BE832175A (fr)	1975-12-01	Procede de preparation de produits alimentaires
FR2319626A1 (fr)	1977-02-25	Procede de preparation de dinitriles insatures et nouveaux produits ainsi obtenus
BE824671A (fr)	1975-07-22	Procede de preparation d'iodophores et produits obtenus
BE836476A (fr)	1976-06-10	Procede de production de carbonylaldiminomethanephosphonates et nouveaux produits ainsi obtenus
FR2293729A1 (fr)	1976-07-02	Procede de preparation de photorecepteurs electrostatographiques et nouveaux produits ainsi obtenus
BE832665A (fr)	1976-02-23	Procede perfectionne de preparation de cyanoguanidines et produits obtenus
FR2293155A1 (fr)	1976-07-02	Produit alimentaire et procede pour sa preparation
FR2352820A1 (fr)	1977-12-23	Procede de preparation de composes de 7-aminocephem en utilisant des champignons de moisissures et nouveaux produits ainsi obtenus
BE854622A (fr)	1977-09-01	Procede de preparation de polyesters et produits ainsi obtenus
FR2297860A1 (fr)	1976-08-13	Procede de preparation de 2-hydroxyalkylphosphines et nouveaux produits ainsi obtenus
BE787367A (fr)	1972-12-01	Procede de preparation de tetraalkylpyrazines et produits obtenus
BE832662A (fr)	1976-02-23	Procede perfectionne de preparation de thiourees et produits obtenus
FR2293431A1 (fr)	1976-07-02	Procede de production de 2-amino-3-cyanothiophenes et produits obtenus
BE823526A (fr)	1975-06-18	Procede de preparation d'hydroxyethercarboxylates et nouveaux produits ainsi obtenus
FR2288102A1 (fr)	1976-05-14	Procede de preparation de 25-hydroxycholesterols et produits obtenus
BE806410A (fr)	1974-02-15	Procede de preparation d'alkylhydroxybenzenes et produits obtenus

Legal Events

Date	Code	Title	Description
1993-06-29	CCPA	Application for a supplementary protection certificate	Free format text: 093C0128
1994-09-27	CCPV	Grant of a supplementary protection certificate	Free format text: 093C0128, EXPIRES 19970628
1995-01-01	RE20	Patent expired	Owner name: FARMITALIA CARLO ERBA S.R.L. Effective date: 19950321

Date

Code

Title

Description

1993-06-29

CCPA

Application for a supplementary protection certificate

Free format text: 093C0128

1994-09-27

CCPV

Grant of a supplementary protection certificate

Free format text: 093C0128, EXPIRES 19970628

1995-01-01

RE20

Patent expired

Owner name: FARMITALIA CARLO ERBA S.R.L.

Effective date: 19950321