BA98300A - Pirolidin derivati - Google Patents

Pirolidin derivati

Info

Publication number: BA98300A
Authority: BA; Bosnia and Herzegovina
Prior art keywords: chem; formula; pyrrolidine derivatives; pyrrolidine; ch2s
Prior art date: 1989-03-17

Application number

BA980300A

Other languages

English (en)

Inventor

Alexander Roderick Mackenzie

Peter Edward Cross

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-17

Filing date

1998-03-30

Publication date

2001-09-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10653525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BA98300(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-03-30 Application filed by Pfizer filed Critical Pfizer

2001-09-14 Publication of BA98300A publication Critical patent/BA98300A/bs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

BA980300A 1989-03-17 1998-03-30 Pirolidin derivati BA98300A (bs)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898906166A GB8906166D0 (en)	1989-03-17	1989-03-17	Therapeutic agents
YU52790A YU47587B (sh)	1989-03-17	1990-03-16	Pirolidin derivati

Publications (1)

Publication Number	Publication Date
BA98300A true BA98300A (bs)	2001-09-14

Family

ID=10653525

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BA980300A BA98300A (bs)	1989-03-17	1998-03-30	Pirolidin derivati

Country Status (37)

Country	Link
US (1)	US5096890B1 (bs)
EP (1)	EP0388054B1 (bs)
JP (2)	JPH0764809B2 (bs)
KR (2)	KR920008166B1 (bs)
CN (1)	CN1023007C (bs)
AT (1)	ATE96783T1 (bs)
AU (1)	AU614224B2 (bs)
BA (1)	BA98300A (bs)
CA (1)	CA2012295C (bs)
CL (1)	CL2003002756A1 (bs)
CY (2)	CY1812A (bs)
CZ (1)	CZ280053B6 (bs)
DD (1)	DD292911A5 (bs)
DE (2)	DE122005000022I2 (bs)
DK (1)	DK0388054T3 (bs)
EG (1)	EG18951A (bs)
ES (1)	ES2060020T3 (bs)
FI (1)	FI95573C (bs)
GB (1)	GB8906166D0 (bs)
HK (1)	HK130294A (bs)
HU (2)	HU217433B (bs)
IE (1)	IE62515B1 (bs)
IL (1)	IL93694A (bs)
LU (1)	LU91161I2 (bs)
MX (1)	MX9319890A (bs)
MY (1)	MY105527A (bs)
NL (1)	NL300191I2 (bs)
NO (2)	NO176316C (bs)
NZ (1)	NZ232958A (bs)
PL (1)	PL164136B1 (bs)
PT (1)	PT93443B (bs)
RU (2)	RU1833374C (bs)
SG (1)	SG143394G (bs)
SK (1)	SK129590A3 (bs)
UA (1)	UA18263A (bs)
YU (1)	YU47587B (bs)
ZA (1)	ZA901982B (bs)

Families Citing this family (68)

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GB9518953D0 (en) *	1995-09-15	1995-11-15	Pfizer Ltd	Pharmaceutical formulations
US5684031A (en) *	1996-02-01	1997-11-04	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) *	1996-02-01	1997-09-30	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
EP0948964B1 (en) *	1996-12-02	2003-04-02	Kyorin Pharmaceutical Co., Ltd.	Novel n-substituted pyrrolidine derivatives and process for preparing the same
US6131129A (en) *	1997-07-30	2000-10-10	Sony Corporation Of Japan	Computer system within an AV/C based media changer subunit providing a standarized command set
US6693202B1 (en)	1999-02-16	2004-02-17	Theravance, Inc.	Muscarinic receptor antagonists
IL141235A (en) *	2000-02-09	2012-04-30	Novartis Int Pharm Ltd	Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia
US6653339B2 (en)	2001-08-15	2003-11-25	Pfizer Inc.	Method of treating irritable bowel syndrome
CA2464223C (en) *	2001-10-26	2009-05-26	Pharmacia & Upjohn Company	Quarternary ammonium compounds and their use as antimuscarinic agents
SE0103668D0 (sv) *	2001-11-02	2001-11-02	Astrazeneca Ab	Method for the treatment of overactive blader
MXPA04003806A (es) *	2001-11-05	2005-04-08	Upjohn Co	Aerosol antimuscarinico.
GB0129962D0 (en) *	2001-12-14	2002-02-06	Pfizer Ltd	Method of treatment
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ATE419236T1 (de)	2002-07-08	2009-01-15	Ranbaxy Lab Ltd	3,6-disubstituierte azabicyclo-3.1.0 hexan- derivate als muscarinische rezeptorantagonisten
WO2004014853A1 (en)	2002-07-31	2004-02-19	Ranbaxy Laboratories Limited	3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
EP1545508A4 (en)	2002-08-09	2009-11-25	Ranbaxy Lab Ltd	3,6-DISUBSTITUTED AZABICYCLO ¬3.1.0 HEXANE DERIVATIVES AS USEFUL AS MUSCARINIC RECEPTOR AGONISTS
JP2006501236A (ja)	2002-08-23	2006-01-12	ランバクシーラボラトリーズリミテッド	ムスカリン性レセプター拮抗薬としてのフルオロおよびスルホニルアミノ含有３，６−二置換アザビシクロ（３．１．０）ヘキサン誘導体
TW200412945A (en) *	2002-10-25	2004-08-01	Upjohn Co	Quaternary ammonium compounds
TW200800953A (en) *	2002-10-30	2008-01-01	Theravance Inc	Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
ATE400553T1 (de)	2002-12-10	2008-07-15	Ranbaxy Lab Ltd	3,6-disubstituierte azabicyclo 3.1.0 - hexanderivative als antagonisten des muscarinrezeptors
US7501443B2 (en)	2002-12-23	2009-03-10	Ranbaxy Laboratories Limited	Flavaxate derivatives as muscarinic receptor antagonists
EP1583741A1 (en)	2002-12-23	2005-10-12	Ranbaxy Laboratories, Limited	1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
US7488748B2 (en)	2003-01-28	2009-02-10	Ranbaxy Laboratories Limited	3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
WO2004089892A2 (en)	2003-04-01	2004-10-21	Theravance, Inc.	Diarylmethyl and related compounds having beta2 andrenergic receptor agonist and muscarinic receptor antagonist activity
EP1618091A1 (en)	2003-04-09	2006-01-25	Ranbaxy Laboratories, Ltd.	Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
JP2006514978A (ja)	2003-04-10	2006-05-18	ランバクシーラボラトリーズリミテッド	ムスカリン受容体アンタゴニストである置換アザビシクロヘキサン誘導体
EP1615887A1 (en)	2003-04-10	2006-01-18	Ranbaxy Laboratories, Ltd.	Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
EA009387B1 (ru)	2003-04-11	2007-12-28	Рэнбакси Лабораториз Лимитед	Азабициклические производные в качестве антагонистов мускаринового рецептора
US20040242569A1 (en) *	2003-04-15	2004-12-02	Pfizer Inc.	Quatemary ammonium compounds
WO2004091597A2 (en) *	2003-04-15	2004-10-28	Pharmacia & Upjohn Company Llc	Method of treating irritable bowel syndrome (ibs)
MXPA05011225A (es) *	2003-04-18	2005-12-14	Pharmacia & Upjohn Co Llc	Politerapias.
TW200510298A (en)	2003-06-13	2005-03-16	Theravance Inc	Substituted pyrrolidine and related compounds
EP1644356A1 (en)	2003-07-11	2006-04-12	Theravance, Inc.	Substituted 4-amino-1-benzylpiperidine compounds
JP2007528414A (ja) *	2004-03-11	2007-10-11	セラヴァンス，インコーポレーテッド	ムスカリンレセプターアンタゴニストとしての有用なジフェニルメチル化合物
EP1723142A1 (en) *	2004-03-11	2006-11-22	Theravance, Inc.	Diphenylmethyl compounds useful as muscarinic receptor antagonists
WO2005092341A1 (en) *	2004-03-22	2005-10-06	Ranbaxy Laboratories Limited	Combination therapy for lower urinary tract symptoms
BRPI0617674A2 (pt)	2005-10-19	2011-08-02	Ranbaxy Lab Ltd	composições farmacêuticas e seus usos
US20070197630A1 (en) *	2005-12-27	2007-08-23	Valeriano Merli	Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof
AR062676A1 (es)	2006-09-07	2008-11-26	Medichem Sa	Procedimiento mejorado para preparar compuestos de pirrolidina 1,3-disustituidas
EP2114972A2 (en) *	2006-12-13	2009-11-11	Gilead Sciences, Inc.	Monophosphates as mutual prodrugs of muscarinic receptor antagonists and beta-agonists for the treatment of copd and chronic bronchitis
WO2008100651A2 (en) *	2007-01-05	2008-08-21	Dr. Reddy's Laboratories Ltd.	Preparation of darifenacin and its salts
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WO2008152497A1 (en) *	2007-06-15	2008-12-18	Medichem, S.A.	Method for determining enantiomeric purity of darifenacin and intermediates
US20090005431A1 (en) *	2007-06-30	2009-01-01	Auspex Pharmaceuticals, Inc.	Substituted pyrrolidines
US20090018346A1 (en) *	2007-07-13	2009-01-15	Medichem, S.A.	Amorphous Form Of Darifenacin Hydrobromide And Processes For The Preparation Thereof
CZ200845A3 (cs) *	2008-01-28	2009-09-02	Zentiva, A. S.	Zpusob prípravy Darifenacinu
WO2009125430A2 (en) *	2008-03-17	2009-10-15	Matrix Laboratoires Limited	Improved process for producing darifenacin
EP2261205A4 (en) *	2008-04-02	2012-06-06	Kaneka Corp	PROCESS FOR PRODUCING (S) -3- (1-CYANO-1,1-DIPHENYLMETHYL) -PYRROLIDINE
US20110144354A1 (en) *	2008-09-22	2011-06-16	Watson Pharma Private Limited	Process for Preparation of Darifenacin and Intermediates Used in the Process
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KR20120025519A (ko)	2009-05-15	2012-03-15	레드엑스 파마 리미티드	산화환원 약물 유도체
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1989
- 1989-03-17 GB GB898906166A patent/GB8906166D0/en active Pending
1990
- 1990-03-02 DE DE200512000022 patent/DE122005000022I2/de active Active
- 1990-03-02 AT AT90302269T patent/ATE96783T1/de active
- 1990-03-02 EP EP90302269A patent/EP0388054B1/en not_active Expired - Lifetime
- 1990-03-02 DK DK90302269.7T patent/DK0388054T3/da active
- 1990-03-02 ES ES90302269T patent/ES2060020T3/es not_active Expired - Lifetime
- 1990-03-02 DE DE90302269T patent/DE69004302T2/de not_active Expired - Lifetime
- 1990-03-09 IL IL9369490A patent/IL93694A/en not_active IP Right Cessation
- 1990-03-13 US US07493068 patent/US5096890B1/en not_active Expired - Lifetime
- 1990-03-14 HU HU580/90A patent/HU217433B/hu unknown
- 1990-03-14 MX MX1989090A patent/MX9319890A/es unknown
- 1990-03-15 JP JP2065521A patent/JPH0764809B2/ja not_active Expired - Lifetime
- 1990-03-15 CA CA002012295A patent/CA2012295C/en not_active Expired - Lifetime
- 1990-03-15 ZA ZA901982A patent/ZA901982B/xx unknown
- 1990-03-15 PT PT93443A patent/PT93443B/pt not_active IP Right Cessation
- 1990-03-15 KR KR1019900003453A patent/KR920008166B1/ko not_active IP Right Cessation
- 1990-03-15 EG EG17090A patent/EG18951A/xx active
- 1990-03-16 PL PL90284342A patent/PL164136B1/pl unknown
- 1990-03-16 SK SK1295-90A patent/SK129590A3/sk not_active IP Right Cessation
- 1990-03-16 NO NO901241A patent/NO176316C/no not_active IP Right Cessation
- 1990-03-16 YU YU52790A patent/YU47587B/sh unknown
- 1990-03-16 MY MYPI90000416A patent/MY105527A/en unknown
- 1990-03-16 IE IE95590A patent/IE62515B1/en not_active IP Right Cessation
- 1990-03-16 RU SU904743599A patent/RU1833374C/ru active
- 1990-03-16 CZ CS901295A patent/CZ280053B6/cs not_active IP Right Cessation
- 1990-03-16 FI FI901333A patent/FI95573C/fi active Protection Beyond IP Right Term
- 1990-03-16 UA UA4743599A patent/UA18263A/uk unknown
- 1990-03-16 DD DD90338829A patent/DD292911A5/de not_active IP Right Cessation
- 1990-03-16 NZ NZ232958A patent/NZ232958A/en unknown
- 1990-03-16 AU AU51402/90A patent/AU614224B2/en not_active Expired
- 1990-03-17 CN CN90101543A patent/CN1023007C/zh not_active Expired - Lifetime
1991
- 1991-03-13 RU SU914894696A patent/RU2015965C1/ru active
1992
- 1992-08-12 KR KR1019920014485A patent/KR960015142B1/ko not_active IP Right Cessation
1994
- 1994-09-26 JP JP6229807A patent/JPH07149640A/ja active Pending
- 1994-10-03 SG SG143394A patent/SG143394G/en unknown
- 1994-11-24 HK HK130294A patent/HK130294A/xx not_active IP Right Cessation
1995
- 1995-06-28 HU HU95P/P00505P patent/HU211640A9/hu active Protection Beyond IP Right Term
- 1995-10-20 CY CY181295A patent/CY1812A/xx unknown
1998
- 1998-03-30 BA BA980300A patent/BA98300A/bs unknown
2003
- 2003-12-26 CL CL200302756A patent/CL2003002756A1/es unknown
2005
- 2005-04-01 NO NO2005008C patent/NO2005008I2/no unknown
- 2005-04-04 CY CY2005005C patent/CY2005005I2/el unknown
- 2005-04-08 NL NL300191C patent/NL300191I2/nl unknown
- 2005-04-11 LU LU91161C patent/LU91161I2/fr unknown

Also Published As

Publication number	Publication date
HU217433B (hu)	2000-01-28
EG18951A (en)	1994-03-30
CN1045580A (zh)	1990-09-26
NO2005008I2 (no)	2006-11-27
YU52790A (sh)	1992-07-20
FI901333A0 (fi)	1990-03-16
AU5140290A (en)	1990-09-20
JPH02282360A (ja)	1990-11-19
US5096890B1 (en)	1995-03-28
MX9319890A (es)	1993-08-01
NO176316C (no)	1995-03-15
FI95573C (fi)	1996-02-26
NL300191I2 (nl)	2005-08-01
CA2012295C (en)	1996-11-12
ATE96783T1 (de)	1993-11-15
DE69004302D1 (de)	1993-12-09
FI95573B (fi)	1995-11-15
HU901580D0 (en)	1990-06-28
DE122005000022I2 (de)	2006-02-02
ZA901982B (en)	1991-10-30
DD292911A5 (de)	1991-08-14
IE900955L (en)	1990-09-17
SG143394G (en)	1995-01-13
JPH0764809B2 (ja)	1995-07-12
CZ280053B6 (cs)	1995-10-18
CY1812A (en)	1995-10-20
IL93694A (en)	1994-08-26
NO2005008I1 (en)	2005-04-11
EP0388054B1 (en)	1993-11-03
US5096890A (en)	1992-03-17
MY105527A (en)	1994-10-31
NZ232958A (en)	1992-05-26
YU47587B (sh)	1995-10-24
RU1833374C (ru)	1993-08-07
SK278434B6 (en)	1997-05-07
CY2005005I1 (el)	2010-07-28
PT93443B (pt)	1996-02-29
NO901241D0 (no)	1990-03-16
NO901241L (no)	1990-09-18
PT93443A (pt)	1990-11-07
CL2003002756A1 (es)	2005-02-11
RU2015965C1 (ru)	1994-07-15
CZ129590A3 (en)	1995-05-17
NL300191I1 (nl)	2005-07-01
CA2012295A1 (en)	1990-09-17
KR960015142B1 (ko)	1996-11-01
LU91161I2 (fr)	2005-06-13
GB8906166D0 (en)	1989-05-04
CY2005005I2 (el)	2010-07-28
EP0388054A1 (en)	1990-09-19
ES2060020T3 (es)	1994-11-16
DE69004302T2 (de)	1994-02-24
AU614224B2 (en)	1991-08-22
IE62515B1 (en)	1995-02-08
SK129590A3 (en)	1997-05-07
KR900014367A (ko)	1990-10-23
PL164136B1 (pl)	1994-06-30
KR920008166B1 (ko)	1992-09-24
CN1023007C (zh)	1993-12-08
DK0388054T3 (da)	1993-12-06
NO176316B (no)	1994-12-05
IL93694A0 (en)	1990-12-23
DE122005000022I1 (de)	2005-08-04
HK130294A (en)	1994-12-02
HU211640A9 (en)	1995-12-28
UA18263A (uk)	1997-12-25
JPH07149640A (ja)	1995-06-13
HUT58313A (en)	1992-02-28

Publication	Publication Date	Title
US5096890B1 (en)	1995-03-28	Pyrrolidine derivatives
DE69007126D1 (de)	1994-04-07	Muscarin-rezeptor-antagonisten.
FI922835A0 (fi)	1992-06-17	Menetelmä terapeuttisesti aktiivisten piperidiinijohdannaisten valmistamiseksi
DE69006745D1 (de)	1994-03-24	Muscarin-rezeptor-antagonisten.