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AU706436B2 - Novel compounds with analgesic effect - Google Patents

Novel compounds with analgesic effect Download PDF

Info

Publication number
AU706436B2
AU706436B2 AU12163/97A AU1216397A AU706436B2 AU 706436 B2 AU706436 B2 AU 706436B2 AU 12163/97 A AU12163/97 A AU 12163/97A AU 1216397 A AU1216397 A AU 1216397A AU 706436 B2 AU706436 B2 AU 706436B2
Authority
AU
Australia
Prior art keywords
hydrates
acceptable salts
prodrugs
isoforms
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU12163/97A
Other languages
English (en)
Other versions
AU1216397A (en
Inventor
Edward Roberts
Claes Wahlestedt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca Canada Inc
Original Assignee
Astra Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc
Publication of AU1216397A publication Critical patent/AU1216397A/en
Application granted granted Critical
Publication of AU706436B2 publication Critical patent/AU706436B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU12163/97A 1995-12-22 1996-12-11 Novel compounds with analgesic effect Ceased AU706436B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9504662 1995-12-22
SE9504662A SE9504662D0 (sv) 1995-12-22 1995-12-22 New compounds
PCT/SE1996/001636 WO1997023467A1 (en) 1995-12-22 1996-12-11 Novel compounds with analgesic effect

Publications (2)

Publication Number Publication Date
AU1216397A AU1216397A (en) 1997-07-17
AU706436B2 true AU706436B2 (en) 1999-06-17

Family

ID=20400740

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12163/97A Ceased AU706436B2 (en) 1995-12-22 1996-12-11 Novel compounds with analgesic effect

Country Status (21)

Country Link
EP (1) EP0873322A1 (no)
JP (1) JP2000502680A (no)
KR (1) KR19990076649A (no)
CN (1) CN1209126A (no)
AU (1) AU706436B2 (no)
BR (1) BR9612206A (no)
CA (1) CA2239162A1 (no)
CZ (1) CZ176798A3 (no)
EE (1) EE9800195A (no)
HU (1) HUP9900105A3 (no)
IL (1) IL124997A0 (no)
IS (1) IS4768A (no)
NO (1) NO982863L (no)
NZ (1) NZ324888A (no)
PL (1) PL327538A1 (no)
SE (1) SE9504662D0 (no)
SK (1) SK81998A3 (no)
TR (1) TR199801184T2 (no)
TW (1) TW360641B (no)
WO (1) WO1997023467A1 (no)
ZA (1) ZA9610355B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6441172B1 (en) 1996-11-07 2002-08-27 Torrey Pines Institute For Molecular Studies Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
GB9804734D0 (en) * 1998-03-05 1998-04-29 Pfizer Ltd Compounds
EE9900336A (et) 1999-10-27 2000-10-16 Bellakem O� Tsükkeltegevuse seade polümeerühendeid sisaldavate jäätmete utiliseerimiseks
RU2186295C2 (ru) 1999-10-27 2002-07-27 Беллакем Ою Установка циклического действия для утилизации отходов, содержащих полимерные соединения
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196150B (it) * 1984-06-19 1988-11-10 Poli Ind Chimica Spa Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono
US5028610A (en) * 1987-03-18 1991-07-02 Sankyo Company Limited N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use
US4829065A (en) * 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4826844A (en) * 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
MY111348A (en) * 1993-07-30 1999-11-30 Ardent Pharmaceuticals Inc Opioid diarylmethylpiperazines and piperidines

Also Published As

Publication number Publication date
SE9504662D0 (sv) 1995-12-22
MX9804797A (es) 1998-10-31
KR19990076649A (ko) 1999-10-15
PL327538A1 (en) 1998-12-21
HUP9900105A2 (hu) 1999-04-28
ZA9610355B (en) 1997-06-23
NO982863D0 (no) 1998-06-19
EP0873322A1 (en) 1998-10-28
NO982863L (no) 1998-06-19
TR199801184T2 (xx) 1998-09-21
EE9800195A (et) 1998-12-15
IL124997A0 (en) 1999-01-26
HUP9900105A3 (en) 2000-05-29
JP2000502680A (ja) 2000-03-07
SK81998A3 (en) 1998-11-04
TW360641B (en) 1999-06-11
IS4768A (is) 1998-06-10
NZ324888A (en) 1999-01-28
AU1216397A (en) 1997-07-17
CN1209126A (zh) 1999-02-24
BR9612206A (pt) 1999-07-13
CA2239162A1 (en) 1997-07-03
CZ176798A3 (cs) 1998-09-16
WO1997023467A1 (en) 1997-07-03

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired