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AU6455896A - Novel factor viii:c polypeptide analogs with altered metal-binding properties - Google Patents

Novel factor viii:c polypeptide analogs with altered metal-binding properties

Info

Publication number
AU6455896A
AU6455896A AU64558/96A AU6455896A AU6455896A AU 6455896 A AU6455896 A AU 6455896A AU 64558/96 A AU64558/96 A AU 64558/96A AU 6455896 A AU6455896 A AU 6455896A AU 6455896 A AU6455896 A AU 6455896A
Authority
AU
Australia
Prior art keywords
factor viii
binding properties
polypeptide analogs
novel factor
altered metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64558/96A
Inventor
Fred E. Cohen
David T. Hung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of AU6455896A publication Critical patent/AU6455896A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU64558/96A 1995-07-11 1996-07-09 Novel factor viii:c polypeptide analogs with altered metal-binding properties Abandoned AU6455896A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87195P 1995-07-11 1995-07-11
US000871 1995-07-11
PCT/US1996/011438 WO1997003193A1 (en) 1995-07-11 1996-07-09 Novel factor viii:c polypeptide analogs with altered metal-binding properties

Publications (1)

Publication Number Publication Date
AU6455896A true AU6455896A (en) 1997-02-10

Family

ID=21693379

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64558/96A Abandoned AU6455896A (en) 1995-07-11 1996-07-09 Novel factor viii:c polypeptide analogs with altered metal-binding properties

Country Status (2)

Country Link
AU (1) AU6455896A (en)
WO (1) WO1997003193A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180371B1 (en) 1996-06-26 2001-01-30 Emory University Modified factor VIII
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
US7560107B2 (en) 1996-06-26 2009-07-14 Emory University Modified factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
EP1141313A2 (en) 1998-12-31 2001-10-10 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
PT1750733E (en) 2004-05-03 2014-02-14 Baxter Healthcare Sa Method of administering porcine b-domainless fviii
EP1598367A1 (en) * 2004-05-18 2005-11-23 ZLB Behring GmbH Modified coagulation factors with enhanced stability and their derivatives
EP1816201A1 (en) 2006-02-06 2007-08-08 CSL Behring GmbH Modified coagulation factor VIIa with extended half-life
EP2097096B1 (en) 2006-12-22 2017-05-31 CSL Behring GmbH Modified coagulation factors with prolonged in vivo half-life
KR101648734B1 (en) 2008-06-24 2016-08-18 체에스엘 베링 게엠베하 Factor VIII, von Willebrand factor or complexes thereof with prolonged in vivo half-life
DK2635297T3 (en) 2010-11-05 2019-05-06 Baxalta GmbH A NEW VARIANT OF ANTIHEMOPHIL FACTOR VIII, WHICH HAS INCREASED SPECIFIC ACTIVITY
DK2814502T3 (en) 2012-02-15 2017-12-18 Csl Behring Gmbh Von Willebrand Factor variants with improved Factor VIII binding affinity
EP2796145B1 (en) 2013-04-22 2017-11-01 CSL Ltd. A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge
AU2015283822B2 (en) 2014-07-02 2019-10-03 CSL Behring Lengnau AG Modified von willebrand factor
CN107406493B (en) 2015-03-06 2021-08-13 康诺贝林伦瑙有限公司 Modified von Willebrand factor with improved half-life
SG11201708754XA (en) 2015-05-22 2017-12-28 Csl Behring Recombinant Facility Ag Methods for preparing modified von willebrand factor
SG10201910896UA (en) 2015-05-22 2020-01-30 CSL Behring Lengnau AG Truncated von willebrand factor polypeptides for treating hemophilia
CA3010720A1 (en) 2016-01-07 2017-07-13 Csl Behring Recombinant Facility Ag Mutated truncated von willebrand factor
KR20180098404A (en) 2016-01-07 2018-09-03 체에스엘 베링 리컴비넌트 퍼실리티 아게 Mutated von Willebrand factor
US11890327B2 (en) 2016-11-11 2024-02-06 CSL Behring Lengnau AG Truncated von Willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder
JP7252890B2 (en) 2016-11-11 2023-04-05 ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト Truncated von Willebrand factor polypeptides for treating hemophilia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE465222C5 (en) * 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab A recombinant human factor VIII derivative and process for its preparation

Also Published As

Publication number Publication date
WO1997003193A1 (en) 1997-01-30

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