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AU6339190A - Process for inactivating viruses in blood and blood products - Google Patents

Process for inactivating viruses in blood and blood products

Info

Publication number
AU6339190A
AU6339190A AU63391/90A AU6339190A AU6339190A AU 6339190 A AU6339190 A AU 6339190A AU 63391/90 A AU63391/90 A AU 63391/90A AU 6339190 A AU6339190 A AU 6339190A AU 6339190 A AU6339190 A AU 6339190A
Authority
AU
Australia
Prior art keywords
blood
products
inactivating viruses
blood products
adsorbents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU63391/90A
Other versions
AU635068B2 (en
Inventor
Bernd Lambrecht
Harald Mohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Original Assignee
Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6389298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU6339190(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Blutspendedienst der Landsverbande des Deutschen Roten Kreuses filed Critical Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Publication of AU6339190A publication Critical patent/AU6339190A/en
Application granted granted Critical
Publication of AU635068B2 publication Critical patent/AU635068B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

The invention relates to a process for the selective removal of photodynamic substances from blood and blood products, where the purification takes place on adsorbents. An arrangement which has proved particularly advantageous for this purpose is one in which the blood or the relevant blood fraction is passed over a separating column which contains the adsorbent.
AU63391/90A 1989-09-13 1990-09-08 Process for inactivating viruses in blood and blood products Expired AU635068B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3930510 1989-09-13
DE3930510A DE3930510A1 (en) 1989-09-13 1989-09-13 PROCESS FOR INACTIVATING VIRUSES IN BLOOD AND BLOOD PRODUCTS

Publications (2)

Publication Number Publication Date
AU6339190A true AU6339190A (en) 1991-04-18
AU635068B2 AU635068B2 (en) 1993-03-11

Family

ID=6389298

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63391/90A Expired AU635068B2 (en) 1989-09-13 1990-09-08 Process for inactivating viruses in blood and blood products

Country Status (14)

Country Link
EP (2) EP0593098A3 (en)
JP (1) JP2965695B2 (en)
AT (1) ATE161681T1 (en)
AU (1) AU635068B2 (en)
CA (1) CA2065842C (en)
CS (1) CS76692A3 (en)
DE (3) DE3930510A1 (en)
DK (1) DK0491757T4 (en)
ES (1) ES2113347T5 (en)
FI (1) FI99192C (en)
HU (1) HU215131B (en)
NO (1) NO300911B1 (en)
RU (1) RU2036235C1 (en)
WO (1) WO1991003933A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639376A (en) * 1994-01-10 1997-06-17 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
US5817237A (en) * 1994-01-10 1998-10-06 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
US5922278A (en) * 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
US6348309B1 (en) * 1989-09-13 2002-02-19 Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US6951713B2 (en) 1997-01-06 2005-10-04 Cerus Corporation Absorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7037642B2 (en) 1997-01-06 2006-05-02 Cerus Corporation Removing compounds from blood products with porous particles immobilized in a matrix
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571666A (en) * 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
DE9102709U1 (en) * 1991-03-07 1991-05-23 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe Blood bag arrangement
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
AU4107396A (en) 1992-03-02 1996-06-06 Cerus Corporation Synthetic media for blood components
US6207107B1 (en) * 1992-10-05 2001-03-27 Baxter International Inc. Steam sterilizable system for inactivating viral contaminants in body fluids
JPH09500015A (en) * 1993-06-23 1997-01-07 ニューヨーク ブラッド センター，インコーポレイティド System for virus inactivation of blood
US5625079A (en) 1993-06-28 1997-04-29 Cerus Corporation Synthesizing psoralen compounds useful as intermediates
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
DE4444045C2 (en) * 1994-12-10 1997-04-17 Behringwerke Ag Method for inactivating viruses using acridine or acridine derivatives
AT406778B (en) * 1996-04-09 2000-09-25 Immuno Ag METHOD FOR DISINEGRATING NUCLEIC ACIDS AND PRODUCING QUALITY-ASSURED BIOLOGICAL PRODUCTS
AU3373297A (en) * 1996-06-17 1998-01-07 Mercury Diagnostics Inc. Electrochemical test device and related methods
ES2210846T3 (en) 1997-11-20 2004-07-01 Cerus Corporation NEW PSORALENES TO ACTIVATE PATHOGEN AGENTS.
US7049110B2 (en) 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7498156B2 (en) 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6610436B1 (en) 1998-09-11 2003-08-26 Gore Enterprise Holdings Catalytic coatings and fuel cell electrodes and membrane electrode assemblies made therefrom
DE19904088A1 (en) * 1999-02-02 2000-09-07 Fressenius Hemocare Gmbh Tubing set for a cell separator for separating blood into its components and method for separating blood into its components
DE19914850A1 (en) * 1999-04-01 2000-10-05 Gerhard Saalmann Device for inactivating viruses, especially human immunodeficiency virus (HIV) from blood products, uses coloring agents and radiation
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
TW590780B (en) 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7985588B2 (en) 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
DE10031851B4 (en) * 2000-07-04 2005-10-13 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Photodynamic treatment and UV-B irradiation of a platelet suspension
EP1469891B1 (en) * 2002-02-01 2009-04-15 CaridianBCT Biotechnologies, LLC Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
WO2015179880A1 (en) * 2014-05-23 2015-11-26 Овик Леонардович МКРТЧЯН Method for inactivating, on medical instruments, viruses containing rna and dna, and apparatus for implementing same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2827109C2 (en) * 1977-06-24 1986-10-30 Asahi Kasei Kogyo K.K., Osaka Method and device for the separation of organic compounds from plasma proteins of the blood
JPS5665071A (en) * 1979-11-01 1981-06-02 Asahi Chem Ind Co Ltd Photo-oxidation treating agent
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
JPS61275228A (en) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド Photodynamic inactivity of virus in therapeutical protein composition
US4775625A (en) * 1986-11-21 1988-10-04 The Medical College Of Wisconsin, Inc. Inactivating enveloped viruses with a merocyanine dye
DE3717951C1 (en) * 1987-05-25 1988-11-24 Shanmugam Murugavel Use of silica gel to detoxify blood
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
DE3805459A1 (en) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh METHOD FOR STERILIZING BLOOD, PLASMA, BLOOD AND PLASMA DERIVATIVES, CELL SUSPENSIONS OR THE LIKE
US5149718A (en) * 1989-01-19 1992-09-22 New York University Biological fluid purification system
JPH07119173B2 (en) * 1989-05-11 1995-12-20 オクラホマ メディカル リサーチ ファウンデーション Pharmaceutical composition using thiazine dye or xanthene dye

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348309B1 (en) * 1989-09-13 2002-02-19 Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
US5935436A (en) * 1994-01-10 1999-08-10 Hemasure Inc. Device for simultaneously removing leukocytes and methylene blue from plasma
US5639376A (en) * 1994-01-10 1997-06-17 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
US6159375A (en) * 1994-01-10 2000-12-12 Hemasure, Inc. Method for removing leukocytes and methylene blue from plasma
US5817237A (en) * 1994-01-10 1998-10-06 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US5922278A (en) * 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US6951713B2 (en) 1997-01-06 2005-10-04 Cerus Corporation Absorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7037642B2 (en) 1997-01-06 2006-05-02 Cerus Corporation Removing compounds from blood products with porous particles immobilized in a matrix
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US9259525B2 (en) 1998-01-06 2016-02-16 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light

Also Published As

Publication number Publication date
DK0491757T4 (en) 2002-04-22
CS76692A3 (en) 1992-08-12
HUT60142A (en) 1992-08-28
FI99192B (en) 1997-07-15
ES2113347T5 (en) 2002-09-16
EP0491757B2 (en) 2002-01-09
HU9200627D0 (en) 1992-05-28
EP0491757B1 (en) 1998-01-07
DE122008000026I2 (en) 2011-05-05
EP0593098A3 (en) 1994-04-27
ES2113347T3 (en) 1998-05-01
DE3930510A1 (en) 1991-03-21
DE122008000026I1 (en) 2008-08-21
CA2065842C (en) 1999-12-21
NO920834D0 (en) 1992-03-03
ATE161681T1 (en) 1998-01-15
DK0491757T3 (en) 1998-09-07
AU635068B2 (en) 1993-03-11
RU2036235C1 (en) 1995-05-27
DE59010793D1 (en) 1998-02-12
HU215131B (en) 1998-09-28
FI920981A0 (en) 1992-03-05
EP0491757A1 (en) 1992-07-01
EP0593098A2 (en) 1994-04-20
JPH05500366A (en) 1993-01-28
CA2065842A1 (en) 1991-03-14
FI99192C (en) 1997-10-27
JP2965695B2 (en) 1999-10-18
NO920834L (en) 1992-03-03
NO300911B1 (en) 1997-08-18
WO1991003933A1 (en) 1991-04-04

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