AU5669498A - Farnesyl transferase inhibitors - Google Patents
Farnesyl transferase inhibitorsInfo
- Publication number
- AU5669498A AU5669498A AU56694/98A AU5669498A AU5669498A AU 5669498 A AU5669498 A AU 5669498A AU 56694/98 A AU56694/98 A AU 56694/98A AU 5669498 A AU5669498 A AU 5669498A AU 5669498 A AU5669498 A AU 5669498A
- Authority
- AU
- Australia
- Prior art keywords
- transferase inhibitors
- farnesyl transferase
- farnesyl
- inhibitors
- transferase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/72—4,7-Endo-alkylene-iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR96/16206 | 1996-12-30 | ||
| FR9616206A FR2757855B1 (en) | 1996-12-30 | 1996-12-30 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| PCT/FR1997/002407 WO1998029390A1 (en) | 1996-12-30 | 1997-12-23 | Farnesyl transferase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU5669498A true AU5669498A (en) | 1998-07-31 |
| AU741921B2 AU741921B2 (en) | 2001-12-13 |
Family
ID=9499293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU56694/98A Ceased AU741921B2 (en) | 1996-12-30 | 1997-12-23 | Farnesyl transferase inhibitors |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP0948483B1 (en) |
| JP (1) | JP2001509147A (en) |
| KR (1) | KR20000062391A (en) |
| AR (1) | AR008950A1 (en) |
| AT (1) | ATE214367T1 (en) |
| AU (1) | AU741921B2 (en) |
| BR (1) | BR9714498A (en) |
| CA (1) | CA2275943A1 (en) |
| CO (1) | CO4920252A1 (en) |
| CZ (1) | CZ233599A3 (en) |
| DE (1) | DE69711081T2 (en) |
| DK (1) | DK0948483T3 (en) |
| DZ (1) | DZ2389A1 (en) |
| EA (1) | EA002114B1 (en) |
| ES (1) | ES2172033T3 (en) |
| FR (1) | FR2757855B1 (en) |
| HU (1) | HUP0001747A3 (en) |
| ID (1) | ID22922A (en) |
| IL (1) | IL130453A0 (en) |
| MA (1) | MA26460A1 (en) |
| NO (1) | NO993225L (en) |
| NZ (1) | NZ336042A (en) |
| PE (1) | PE28199A1 (en) |
| PL (1) | PL334345A1 (en) |
| PT (1) | PT948483E (en) |
| SK (1) | SK88399A3 (en) |
| TN (1) | TNSN97214A1 (en) |
| TR (1) | TR199901502T2 (en) |
| UY (1) | UY24832A1 (en) |
| WO (1) | WO1998029390A1 (en) |
| YU (1) | YU30299A (en) |
| ZA (1) | ZA9711734B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787327B1 (en) * | 1998-12-21 | 2003-01-17 | Aventis Pharma Sa | COMPOSITIONS CONTAINING FARNESYL TRANSFERASE INHIBITORS |
| FR2796640A1 (en) * | 1999-07-22 | 2001-01-26 | Aventis Pharma Sa | New 3,9-ethano-2,3,3a,4,9,9a-hexahydro-1H-benzo (f) isoindole derivatives, are farnesyl transferase inhibitors useful for treating hyperproliferative disorders, e.g. psoriasis, restenosis or especially cancer |
| FR2796641B1 (en) * | 1999-07-22 | 2001-09-21 | Aventis Pharma Sa | NOVEL PROCESS FOR THE PREPARATION OF BENZOPERHYDROISOINDOLE COMPOUNDS |
| FR2845994B1 (en) * | 2002-10-18 | 2006-05-19 | Servier Lab | NOVEL SUBSTITUTED BENZO [E] [1,4] OXAZINO [3,2-G] ISOINDOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| US20060106060A1 (en) * | 2004-03-18 | 2006-05-18 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies (Lansbury) |
| WO2024229406A1 (en) | 2023-05-04 | 2024-11-07 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100362338B1 (en) * | 1993-11-05 | 2003-04-08 | 워너-램버트 캄파니 | Protein: Substituted Di- and Tripeptide Inhibitors of Farnesyl Transferase |
| FR2736641B1 (en) * | 1995-07-10 | 1997-08-22 | Rhone Poulenc Rorer Sa | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
-
1996
- 1996-12-30 FR FR9616206A patent/FR2757855B1/en not_active Expired - Fee Related
-
1997
- 1997-12-03 PE PE1997001089A patent/PE28199A1/en not_active Application Discontinuation
- 1997-12-23 HU HU0001747A patent/HUP0001747A3/en unknown
- 1997-12-23 PT PT97953000T patent/PT948483E/en unknown
- 1997-12-23 DK DK97953000T patent/DK0948483T3/en active
- 1997-12-23 IL IL13045397A patent/IL130453A0/en unknown
- 1997-12-23 ES ES97953000T patent/ES2172033T3/en not_active Expired - Lifetime
- 1997-12-23 ID IDW990618A patent/ID22922A/id unknown
- 1997-12-23 YU YU30299A patent/YU30299A/en unknown
- 1997-12-23 CA CA002275943A patent/CA2275943A1/en not_active Abandoned
- 1997-12-23 SK SK883-99A patent/SK88399A3/en unknown
- 1997-12-23 TR TR1999/01502T patent/TR199901502T2/en unknown
- 1997-12-23 PL PL97334345A patent/PL334345A1/en unknown
- 1997-12-23 AT AT97953000T patent/ATE214367T1/en not_active IP Right Cessation
- 1997-12-23 WO PCT/FR1997/002407 patent/WO1998029390A1/en not_active Application Discontinuation
- 1997-12-23 EP EP97953000A patent/EP0948483B1/en not_active Expired - Lifetime
- 1997-12-23 JP JP52968698A patent/JP2001509147A/en not_active Ceased
- 1997-12-23 CZ CZ992335A patent/CZ233599A3/en unknown
- 1997-12-23 NZ NZ336042A patent/NZ336042A/en unknown
- 1997-12-23 AU AU56694/98A patent/AU741921B2/en not_active Ceased
- 1997-12-23 EA EA199900608A patent/EA002114B1/en not_active IP Right Cessation
- 1997-12-23 DE DE69711081T patent/DE69711081T2/en not_active Expired - Fee Related
- 1997-12-23 BR BR9714498A patent/BR9714498A/en not_active IP Right Cessation
- 1997-12-23 KR KR1019997005966A patent/KR20000062391A/en not_active Application Discontinuation
- 1997-12-26 TN TNTNSN97214A patent/TNSN97214A1/en unknown
- 1997-12-26 MA MA24915A patent/MA26460A1/en unknown
- 1997-12-27 DZ DZ970239A patent/DZ2389A1/en active
- 1997-12-29 CO CO97075391A patent/CO4920252A1/en unknown
- 1997-12-30 AR ARP970106263A patent/AR008950A1/en unknown
- 1997-12-30 ZA ZA9711734A patent/ZA9711734B/en unknown
- 1997-12-30 UY UY24832A patent/UY24832A1/en not_active Application Discontinuation
-
1999
- 1999-06-29 NO NO993225A patent/NO993225L/en not_active Application Discontinuation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |