[go: up one dir, main page]

AU545665B2 - Microbiological production of the amino acid sequences of proinsulin from primates - Google Patents

Microbiological production of the amino acid sequences of proinsulin from primates

Info

Publication number
AU545665B2
AU545665B2 AU66280/81A AU6628081A AU545665B2 AU 545665 B2 AU545665 B2 AU 545665B2 AU 66280/81 A AU66280/81 A AU 66280/81A AU 6628081 A AU6628081 A AU 6628081A AU 545665 B2 AU545665 B2 AU 545665B2
Authority
AU
Australia
Prior art keywords
primates
proinsulin
amino acid
acid sequences
microbiological production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU66280/81A
Other versions
AU6628081A (en
Inventor
Jurgen Groneberg
Hans-Dieter Summ
Friedrich Wengenmayer
Ernst-Ludwig Winnacker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU6628081A publication Critical patent/AU6628081A/en
Application granted granted Critical
Publication of AU545665B2 publication Critical patent/AU545665B2/en
Assigned to AVENTIS PHARMA DEUTSCHLAND GMBH reassignment AVENTIS PHARMA DEUTSCHLAND GMBH Alteration of Name(s) in Register under S187 Assignors: HOECHST A.G.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The process for the preparation of the polypeptide which contains the amino-acid sequence of the proinsulin of primates entails the genetic information for the biosynthesis of the said polypeptide being obtained by means of mRNA from primates, the cDNA being prepared therefrom and inserted into a plasmid, the resulting hybrid plasmid being used to transform microorganisms, and the microorganisms producing the polypeptide being obtained by selection and cultivation.
AU66280/81A 1980-01-19 1981-01-16 Microbiological production of the amino acid sequences of proinsulin from primates Expired AU545665B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803001928 DE3001928A1 (en) 1980-01-19 1980-01-19 GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE
DE30019284 1980-01-19

Publications (2)

Publication Number Publication Date
AU6628081A AU6628081A (en) 1981-07-30
AU545665B2 true AU545665B2 (en) 1985-07-25

Family

ID=6092503

Family Applications (1)

Application Number Title Priority Date Filing Date
AU66280/81A Expired AU545665B2 (en) 1980-01-19 1981-01-16 Microbiological production of the amino acid sequences of proinsulin from primates

Country Status (14)

Country Link
EP (1) EP0032675B1 (en)
JP (1) JPS56104897A (en)
AT (1) ATE5151T1 (en)
AU (1) AU545665B2 (en)
BE (1) BE887129A (en)
CA (1) CA1192153A (en)
DE (2) DE3001928A1 (en)
ES (3) ES498451A0 (en)
FR (1) FR2479851A1 (en)
GB (1) GB2067574B (en)
IT (1) IT1136557B (en)
NL (1) NL8100210A (en)
SE (1) SE8100241L (en)
ZA (1) ZA81292B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU572096B2 (en) * 1982-06-11 1988-05-05 Hoechst A.G. Methylomonas plasmids

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
ZA824218B (en) * 1981-06-29 1983-04-27 Cetus Corp Plasmid for producing human insulin
EP0090433A1 (en) * 1982-03-31 1983-10-05 Genetics Institute, Inc. Creation of DNA sequences encoding modified proinsulin precursors
US7976518B2 (en) 2005-01-13 2011-07-12 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
US9028441B2 (en) 2011-09-08 2015-05-12 Corpak Medsystems, Inc. Apparatus and method used with guidance system for feeding and suctioning

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
NZ187300A (en) * 1977-05-27 1982-08-17 Univ California Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism
NZ188837A (en) * 1977-11-08 1982-09-14 Genentech Inc Method for producing polypeptides using recombinant microbial cloning vehicles (eg plasmids) plasmids and transformed bacteria
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
GR71912B (en) * 1978-08-11 1983-08-16 Univ California
GR70279B (en) * 1979-09-12 1982-09-03 Univ California

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU572096B2 (en) * 1982-06-11 1988-05-05 Hoechst A.G. Methylomonas plasmids

Also Published As

Publication number Publication date
ES499054A0 (en) 1982-06-01
ZA81292B (en) 1982-02-24
EP0032675B1 (en) 1983-10-26
CA1192153A (en) 1985-08-20
JPS56104897A (en) 1981-08-20
BE887129A (en) 1981-07-20
GB2067574A (en) 1981-07-30
IT1136557B (en) 1986-09-03
DE3161251D1 (en) 1984-01-19
ES499053A0 (en) 1982-02-16
GB2067574B (en) 1983-10-19
ES8203101A1 (en) 1982-02-16
ATE5151T1 (en) 1983-11-15
ES8200722A1 (en) 1981-11-01
EP0032675A2 (en) 1981-07-29
ES498451A0 (en) 1981-11-01
JPS642584A (en) 1989-01-06
IT8119180A0 (en) 1981-01-16
EP0032675A3 (en) 1981-11-11
FR2479851A1 (en) 1981-10-09
NL8100210A (en) 1981-08-17
AU6628081A (en) 1981-07-30
SE8100241L (en) 1981-07-20
DE3001928A1 (en) 1981-08-06
ES8205427A1 (en) 1982-06-01

Similar Documents

Publication Publication Date Title
AU2443488A (en) Dna-molecules coding for fmdh control regions and structured gene for a protein having fmdh-activity and their uses
CZ285453B6 (en) Dna encoding aspartokinase iii, micro-organism escherichia transformed thereby and process for preparing l-threonine by making use thereof
GR3032790T3 (en) Materials and methods for hypersecretion of amino acids
EP0156355A3 (en) Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
ZA017370B (en) Novel cytokine zalpha11 ligand
EP1942189A3 (en) Method for producing secreted proteins
UA32548C2 (en) Isolated DNA sequence coding EPSPS ferment, Isolated DNA sequence coding protein, revealING EPSPS activity, recombinant bifilar DNA molecule, a method for producing genetically transformed plants
CA2180103A1 (en) Gene encoding adseverin
JPS55131397A (en) Preparation of l-threonine by fermentation
HU896613D0 (en) Process for the preparation of tgf-betal/beta2 chimer
AU545665B2 (en) Microbiological production of the amino acid sequences of proinsulin from primates
CA2072007A1 (en) Cloning Vector for Use in Lactic Acid Bacteria and a Method for Constructing the Same
EP0139501A3 (en) The manufacture and expression of genes for thaumatin
EP0226979A3 (en) Process for producing the protein of an aequorin activity by using a photoprotein aequorin gene
HUT65492A (en) Biosynthetic process for the preparation of dedydro-amino acid-remainds and tioether-bridge contaning chemical compounds
WO1989009824A3 (en) Gene synthesis
EP1123977A4 (en) GENES ENCODING PROTEINS REGULATING pH OF VACUOLES
DE3681398D1 (en) METHOD FOR THE PRODUCTION OF INSULINE-LIKE GROWTH FACTOR I (IGF-I) AND PLASMIDE FOR THE PRODUCTION THEREOF.
FR2785291B1 (en) PROCESS FOR THE IN VIVO PRODUCTION OF CHEMICALLY DIVERSIFIED PROTEINS BY INCORPORATING NON-CONVENTIONAL AMINO ACIDS
DE69121983D1 (en) Process for the preparation of ascorbic acid 2-phosphate
EP0194818A3 (en) Production of interleukin-2
AU3157893A (en) Process for preparing neuraminidase
MY100385A (en) Process for producing l-amino acids or 5''-inosinic acid by fermentation.

Legal Events

Date Code Title Description
PC Assignment registered

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH

Free format text: FORMER OWNER WAS: HOECHST A.G.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired