AU2050001A - Synthesis of indole-containing spla2 inhibitors - Google Patents
Synthesis of indole-containing spla2 inhibitorsInfo
- Publication number
- AU2050001A AU2050001A AU20500/01A AU2050001A AU2050001A AU 2050001 A AU2050001 A AU 2050001A AU 20500/01 A AU20500/01 A AU 20500/01A AU 2050001 A AU2050001 A AU 2050001A AU 2050001 A AU2050001 A AU 2050001A
- Authority
- AU
- Australia
- Prior art keywords
- indole
- synthesis
- spla2 inhibitors
- containing spla2
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17123099P | 1999-12-16 | 1999-12-16 | |
| US60171230 | 1999-12-16 | ||
| PCT/US2000/032444 WO2001044184A1 (en) | 1999-12-16 | 2000-12-11 | Synthesis of indole-containing spla2 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2050001A true AU2050001A (en) | 2001-06-25 |
Family
ID=22623021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU20500/01A Abandoned AU2050001A (en) | 1999-12-16 | 2000-12-11 | Synthesis of indole-containing spla2 inhibitors |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2050001A (en) |
| WO (1) | WO2001044184A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| JP5406716B2 (en) | 2006-08-07 | 2014-02-05 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | Indole compounds |
| EA019819B1 (en) | 2008-05-23 | 2014-06-30 | ПАНМИРА ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | C crystalline polymorphic form of protein inhibitor activating 5-lipoxygenase, pharmaceutical composition based thereon and use in treatment |
| AR084433A1 (en) | 2010-12-22 | 2013-05-15 | Ironwood Pharmaceuticals Inc | FAAH INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CN107721869A (en) * | 2017-03-30 | 2018-02-23 | 上海雅本化学有限公司 | A kind of synthetic method of the cyanobenzaldehyde of 2 methoxyl group 4 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI811889L (en) * | 1980-06-18 | 1981-12-19 | May & Baker Ltd | PROCEDURE FOR THE PRODUCTION OF PHARMACOLOGICAL ACTIVITIES |
| SI0675110T1 (en) * | 1994-04-01 | 2002-12-31 | Eli Lilly And Company | 1H-Indole-3-glyoxylamide sPLA2 inhibitors |
-
2000
- 2000-12-11 AU AU20500/01A patent/AU2050001A/en not_active Abandoned
- 2000-12-11 WO PCT/US2000/032444 patent/WO2001044184A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001044184A1 (en) | 2001-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |