AU2003286741A1 - Methods and compositions for diagnosis and therapy of parkin-associated disorders - Google Patents
Methods and compositions for diagnosis and therapy of parkin-associated disordersInfo
- Publication number
- AU2003286741A1 AU2003286741A1 AU2003286741A AU2003286741A AU2003286741A1 AU 2003286741 A1 AU2003286741 A1 AU 2003286741A1 AU 2003286741 A AU2003286741 A AU 2003286741A AU 2003286741 A AU2003286741 A AU 2003286741A AU 2003286741 A1 AU2003286741 A1 AU 2003286741A1
- Authority
- AU
- Australia
- Prior art keywords
- parkin
- diagnosis
- therapy
- compositions
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101000619542 Homo sapiens E3 ubiquitin-protein ligase parkin Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000045222 parkin Human genes 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/53—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/9015—Ligases (6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46736003P | 2003-05-02 | 2003-05-02 | |
| US60/467,360 | 2003-05-02 | ||
| PCT/US2003/034268 WO2004098377A2 (en) | 2003-05-02 | 2003-10-28 | Methods and compositions for diagnosis and therapy of parkin-associated disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003286741A8 AU2003286741A8 (en) | 2004-11-26 |
| AU2003286741A1 true AU2003286741A1 (en) | 2004-11-26 |
Family
ID=33435063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003286741A Abandoned AU2003286741A1 (en) | 2003-05-02 | 2003-10-28 | Methods and compositions for diagnosis and therapy of parkin-associated disorders |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003286741A1 (en) |
| WO (1) | WO2004098377A2 (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103866018B (en) | 2005-08-01 | 2016-05-25 | 俄亥俄州立大学研究基金会 | Be used for the method and composition based on MicroRNA of diagnosis, prognosis and the treatment of breast cancer |
| ES2523989T3 (en) | 2005-09-12 | 2014-12-03 | The Ohio State University Research Foundation | Compositions for the therapy of cancers associated with BCL2 |
| JP5451077B2 (en) | 2006-01-05 | 2014-03-26 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | MicroRNA-based methods and compositions for lung cancer diagnosis, prognosis and treatment |
| CA2635616A1 (en) | 2006-01-05 | 2007-07-19 | Carlo M. Croce | Microrna expression abnormalities in pancreatic endocrine and acinar tumors |
| EP2479285B1 (en) | 2006-01-05 | 2014-05-14 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers |
| US7985584B2 (en) | 2006-03-20 | 2011-07-26 | The Ohio State University Research Foundation | MicroRNA fingerprints during human megakaryocytopoiesis |
| ES2447850T3 (en) | 2006-07-13 | 2014-03-13 | The Ohio State University Research Foundation | Methods and compositions based on micro-RNA for the prognosis and treatment of diseases related to the colon |
| JP5426383B2 (en) | 2006-09-19 | 2014-02-26 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | TCL1 expression regulated by miR-29 and miR-181 in chronic lymphocytic leukemia |
| JP5501766B2 (en) | 2006-11-01 | 2014-05-28 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | MicroRNA expression signature to predict survival and metastasis in hepatocellular carcinoma |
| AU2008211142A1 (en) | 2007-01-31 | 2008-08-07 | The Ohio State University Research Foundation | Mic orna-based methods and compositions for the treatment of acute myeloid leukemia |
| EP2559773B1 (en) | 2007-06-08 | 2015-04-22 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Methods for determining a hepatocellular carcinoma subtype |
| EP2167521A4 (en) | 2007-06-15 | 2011-11-23 | Univ Ohio State Res Found | ALL-1 ONCOGEN FUSION PROTEINS TO TARGE TREATMENT OF MICRO-RNA REGULATED BY DROSHA |
| CA2695184A1 (en) | 2007-07-31 | 2009-02-05 | The Ohio State University Research Foundation | Methods for reverting methylation by targeting dnmt3a and dnmt3b |
| JP2010535473A (en) | 2007-08-03 | 2010-11-25 | ズィ、オハイオウ、ステイト、ユーニヴァーサティ、リサーチ、ファウンデイシャン | Superconserved region encoding ncRNA |
| CA2696887C (en) | 2007-08-22 | 2016-06-28 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
| EP2201112A4 (en) | 2007-10-26 | 2011-02-02 | Univ Ohio State Res Found | METHODS FOR IDENTIFYING INTERACTION OF THE "FRAGILE HISTIDINE TRIAD" GENE (FHIT) AND USES THEREOF |
| WO2009152300A1 (en) | 2008-06-11 | 2009-12-17 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Use of mir-26 family as a predictive marker of hepatocellular carcinoma and responsiveness to therapy |
| JP5960060B2 (en) | 2009-11-23 | 2016-08-02 | ジ・オハイオ・ステート・ユニバーシティ | Substances and methods useful for influencing tumor cell growth, migration and invasion |
| CA2816603A1 (en) | 2010-11-12 | 2012-05-18 | The Ohio State University Research Foundation | Materials and methods related to microrna-21, mismatch repair, and colorectal cancer |
| EP2640368B1 (en) | 2010-11-15 | 2020-12-30 | The Ohio State University Research Foundation | Controlled release mucoadhesive systems |
| CN103561750A (en) | 2011-03-07 | 2014-02-05 | 俄亥俄州立大学 | Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer |
| CN104364390B (en) | 2011-10-14 | 2016-08-24 | 俄亥俄州立大学 | Methods and materials related to ovarian cancer |
| CA2859430A1 (en) | 2011-12-13 | 2013-06-20 | Ohio State Innovation Foundation | Methods and compositions related to mir-21 and mir-29a, exosome inhibition, and cancer metastasis |
| CA2866052A1 (en) | 2012-01-20 | 2013-07-25 | The Ohio State University | Breast cancer biomarker signatures for invasiveness and prognosis |
| WO2013113762A1 (en) * | 2012-01-31 | 2013-08-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for predicting the risk of having a cutaneous melanoma in a subject |
| CN107412727B (en) * | 2017-03-16 | 2021-03-26 | 北京热休生物技术有限公司 | Application of the complex formed by the polypeptide of the protein PACRGL and the heat shock protein gp96 in the preparation of a drug for the treatment and prevention of cancer |
| CN112029738B (en) * | 2020-08-18 | 2022-04-29 | 浙江省人民医院 | Human parkin protein acetylation and application thereof in medicine preparation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952221A (en) * | 1996-03-06 | 1999-09-14 | Avigen, Inc. | Adeno-associated virus vectors comprising a first and second nucleic acid sequence |
| US6448041B1 (en) * | 2000-12-18 | 2002-09-10 | Incyte Genomics, Inc. | Colon cancer marker |
| US6855554B2 (en) * | 2001-09-21 | 2005-02-15 | Board Of Regents, The University Of Texas Systems | Methods and compositions for detection of breast cancer |
-
2003
- 2003-10-28 AU AU2003286741A patent/AU2003286741A1/en not_active Abandoned
- 2003-10-28 WO PCT/US2003/034268 patent/WO2004098377A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003286741A8 (en) | 2004-11-26 |
| WO2004098377A2 (en) | 2004-11-18 |
| WO2004098377A3 (en) | 2005-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |