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AU2001289145A1 - Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof - Google Patents

Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof

Info

Publication number
AU2001289145A1
AU2001289145A1 AU2001289145A AU8914501A AU2001289145A1 AU 2001289145 A1 AU2001289145 A1 AU 2001289145A1 AU 2001289145 A AU2001289145 A AU 2001289145A AU 8914501 A AU8914501 A AU 8914501A AU 2001289145 A1 AU2001289145 A1 AU 2001289145A1
Authority
AU
Australia
Prior art keywords
tumor
methods
monoclonal antibody
associated antigen
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001289145A
Inventor
Diane A. Semer
Anne Elizabeth Wennerberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
East Carolina University
Original Assignee
East Carolina University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by East Carolina University filed Critical East Carolina University
Publication of AU2001289145A1 publication Critical patent/AU2001289145A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001289145A 2000-08-18 2001-08-17 Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof Abandoned AU2001289145A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09641499 2000-08-18
US09/641,499 US6596503B1 (en) 2000-08-18 2000-08-18 Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
PCT/US2001/041765 WO2002016401A2 (en) 2000-08-18 2001-08-17 Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2001289145A1 true AU2001289145A1 (en) 2002-03-04

Family

ID=24572648

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001289145A Abandoned AU2001289145A1 (en) 2000-08-18 2001-08-17 Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof

Country Status (7)

Country Link
US (5) US6596503B1 (en)
EP (1) EP1362060A4 (en)
AU (1) AU2001289145A1 (en)
CA (1) CA2419270C (en)
GB (1) GB2383331B (en)
MX (2) MXPA03001460A (en)
WO (1) WO2002016401A2 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
CN102940889A (en) 2003-05-14 2013-02-27 伊缪诺金公司 Drug conjugate composition
AU2012201260B2 (en) * 2003-07-21 2014-10-23 Immunogen, Inc. A CA6 antigen-specific cytotoxic conjugate and methods of using the same
US7834155B2 (en) 2003-07-21 2010-11-16 Immunogen Inc. CA6 antigen-specific cytotoxic conjugate and methods of using the same
DK1660513T5 (en) 2003-07-21 2011-07-18 Immunogen Inc CA6 antigen-specific, cytotoxic conjugate and methods for its use
JP2007529201A (en) * 2004-03-11 2007-10-25 シャーンタ ウェスト インコーポレーティッド Use of RM1 antigen for therapeutic purposes
EP2468304A3 (en) 2005-02-11 2012-09-26 ImmunoGen, Inc. Process for preparing stable drug conjugates
JP2009503105A (en) 2005-08-03 2009-01-29 イミュノジェン・インコーポレーテッド Immune complex preparation
BRPI0520509A2 (en) * 2005-08-22 2009-05-12 Immunogen Inc antibody or epitope binding fragment, polynucleotide, host cell, and method of preparing an antibody or epitope binding fragment
CN104804094A (en) * 2005-08-22 2015-07-29 伊缪诺金公司 CA6 antigen-specificity cytotoxicity conjugate and application method thereof
NZ716641A (en) 2005-08-24 2017-06-30 Immunogen Inc Process for preparing maytansinoid antibody conjugates
CA2651800A1 (en) * 2006-04-24 2007-11-08 Shantha West, Inc. Agrm2 antigen
EP2431053A1 (en) 2006-11-27 2012-03-21 Patrys Limited Novel glycosylated peptide target in neoplastic cells
WO2009015294A1 (en) * 2007-07-24 2009-01-29 Wisconsin Alumni Research Foundation Biomarkers for human papillomavirus-associated cancers
KR101764081B1 (en) 2008-04-30 2017-08-01 이뮤노젠 아이엔씨 Cross-linkers and their uses
WO2010004438A2 (en) 2008-06-16 2010-01-14 Patrys Limited Lm-antibodies, functional fragments, lm-1 target antigen, and methods for making and using same
CA3152591C (en) * 2008-09-09 2023-08-29 Somalogic Operating Co., Inc. Lung cancer biomarkers and uses thereof
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
DK2437790T3 (en) 2009-06-03 2019-05-20 Immunogen Inc conjugation
JP2013506709A (en) 2009-10-06 2013-02-28 イミュノジェン・インコーポレーテッド Effective conjugates and hydrophilic linkers
JP5905003B2 (en) * 2010-07-09 2016-04-20 ソマロジック・インコーポレーテッド Lung cancer biomarkers and their use
BR112013003391B8 (en) 2010-08-13 2022-10-25 Somalogic Inc METHOD TO DIAGNOSE PANCREATIC CANCER IN AN INDIVIDUAL
SG193997A1 (en) 2011-03-29 2013-11-29 Immunogen Inc Process for manufacturing conjugates of improved homogeneity
RS58367B1 (en) 2011-03-29 2019-03-29 Immunogen Inc Preparation of maytansinoid antibody conjugates by a one-step process
JP5986638B2 (en) * 2011-10-24 2016-09-06 ソマロジック・インコーポレーテッド Lung cancer biomarkers and uses thereof
CA2852709A1 (en) 2011-10-28 2013-05-02 Patrys Limited Pat-lm1 epitopes and methods for using same
JP2012161321A (en) * 2012-03-30 2012-08-30 Immunogen Inc Ca6 antigen-specific cytotoxic conjugate, and method using the conjugate
CA2886993A1 (en) 2012-10-04 2014-04-10 Immunogen, Inc. Use of a pvdf membrane to purify cell-binding agent cytotoxic agent conjugates
US9989524B2 (en) * 2013-02-05 2018-06-05 Sanofi Immuno imaging agent for use with antibody-drug conjugate therapy
JP2016515093A (en) 2013-02-05 2016-05-26 サノフイ Immunoimaging agents for use with antibody-drug conjugate therapy
CA2966932A1 (en) 2014-11-19 2016-05-26 Immunogen, Inc. Process for preparing cell-binding agent-cytotoxic agent conjugates
KR20180105233A (en) 2016-02-05 2018-09-27 이뮤노젠 아이엔씨 Efficient methods for preparing cell-binder-cytotoxic agent conjugates
WO2017194568A1 (en) 2016-05-11 2017-11-16 Sanofi Treatment regimen using anti-muc1 maytansinoid immunoconjugate antibody for the treatment of tumors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US5366866A (en) 1991-07-25 1994-11-22 Duke University Method of diagnosing ovarian and endometrial cancer with monoclonal antibodies OXA and OXB
WO1994021294A1 (en) 1993-03-19 1994-09-29 Bigner Darell D Method of treating tumors with antibodies
WO1994021293A1 (en) 1993-03-19 1994-09-29 Duke University Method of treatment of tumors with an antibody binding to tenascin
US5871941A (en) 1995-07-28 1999-02-16 Univ British Columbia Method of testing expression of CA125 antigen in cultured ovarian surface epithelial cells to identify and monitor individuals having a predisposition to develop ovarian cancer
US7037667B1 (en) * 1998-06-01 2006-05-02 Agensys, Inc. Tumor antigen useful in diagnosis and therapy of prostate and colon cancer
US7834155B2 (en) * 2003-07-21 2010-11-16 Immunogen Inc. CA6 antigen-specific cytotoxic conjugate and methods of using the same
DK1660513T5 (en) 2003-07-21 2011-07-18 Immunogen Inc CA6 antigen-specific, cytotoxic conjugate and methods for its use

Also Published As

Publication number Publication date
US8728741B2 (en) 2014-05-20
EP1362060A2 (en) 2003-11-19
GB2383331B (en) 2004-09-29
WO2002016401A3 (en) 2002-04-11
US20070196276A1 (en) 2007-08-23
GB0306083D0 (en) 2003-04-23
EP1362060A4 (en) 2004-09-08
US20120045776A1 (en) 2012-02-23
GB2383331A (en) 2003-06-25
US6596503B1 (en) 2003-07-22
MX347883B (en) 2017-05-16
US7507410B2 (en) 2009-03-24
US20030215895A1 (en) 2003-11-20
WO2002016401A2 (en) 2002-02-28
MXPA03001460A (en) 2004-12-13
US8067186B2 (en) 2011-11-29
CA2419270C (en) 2013-05-14
CA2419270A1 (en) 2002-02-28
US20090155930A1 (en) 2009-06-18
US7351805B2 (en) 2008-04-01

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