AU2000492A - Attracting and ingestion-stimulating agent for cockroach - Google Patents

Description

DESCRIPTION

Attracting and ingestion-stimulating agent for cockroach

TECHNICAL FIELD

The present invention relates to attracting and

ingestion-stimulating agents for cockroaches.

BACKGROUND ART

Cockroach is one of the sanitarily harmful insects most

widely known throughout the world.

In Japan, as the house cockroach are known Periplaneata

fuliginosa S. , P.japonica K. , P.americana L. , Blattella

germanic L. , etc.

In general, it is important for extermination of cockroach

to possess both an attracting activity and an

ingestion-stimulating activity.

We have already provided several cockroach attracting and

ingestion-stimulating agents which stimulataneously possess

the activities both (USP 4,627,981; USP 4,911,907).

Tetralol, naphthol and phenol compounds and

Iristectoramines alchols, which are active ingredients of

these cockroach attracting and ingestion-stimulating agents,

are sufficiently active without any additives. However, they

are often active against male P.americana L. only, and thus

when applied to colonies of other species of cockroach or colonies of female cockroach only, they sometimes produce

lower effects.

DISCLOSURE OF INVENTION

In order to provide more effectively attracting and

ingestion-stimulating agents for cockroach than the prior art

agents, we have investigated a composition comprising;

(a)one or more compounds selected from the group of

1-amino-5,6,7,8-tetrahydronaphthalen , 2-amino-5,6,7,8-

tetrahydronaphthalen , 2-aminomethyl-5,6,7,8-tetrahydro-

naphthalene and a salt thereof ; and

(b)one or more compounds selected from the group of

p-n-butylphenol, p-n-amylphenol, 5,6,7,8-tetrahydro-l-

naphtyhol and 5,6,7,8-tetrahydro-2-naρhthol show a hight

attractant and ingestion-stimulating activity for cockroach.

A more preferred agent for cockroach of the invention is

concerned with a attracting and ingestion-stimulating agent

for cockroach comprising as active ingredients a compound

selected from the group consisting of l-amino-5,6,7,8-

tetrahydronaphthalene, 2-amino-5,6,7,8-tetrahydronaphthalene,

2-aminomethyl-5,6,7,8-tetrahydronaphthalene and a salt

thereof, and a compound selected from the group consisting of

p-n-amylphenol, p-n-butylphenol, 5,6,7,8-tetrahydro-l-

naphthol and 5,6,7,8-tetrahydro-2-naρhthol. All of the compound are known compounds.

1-Amino-5,6,7,8-tetrahydronaphthalene, 2-amino-5,6,7,8-

tetrahydronaphthalene and 2-aminomethy1-5,6,7,8-tetrahydro-

naphthalene are disclosed, for example, in the literature

cited below.

V.S. Misara et al. , J.Indian Chem. Soc. , 1985, 36, 803 S.W. Fenton et al. , J.Am.Chem. Soc, 1955, 77, 979

V.Grinsteins et al. , Lav.RSR Zinat.Akad.Veatis,Kim.Ser. , 1967, 7, 12

As the salt of the compounds, there can be mentioned, for

example, hydrochloric acid salt, oxalic acid salt, citric acid salt, acetic acid salt, phosphoric acid salt, malonic acid

salt, sulfric acid salt, tartaric acid salt, maleic acid salt, lactic acid salt and pyrophosphoric acid salt.

2-Aminomethyl-5,6,7,8-tetrahydronaphthalene is allow to

stand in air to give a salt.

The salt compound has a chemical structure as shown below;

However, none of l-amino-5,6,7,8-tetrahydronaρhthalene

-amino-5,6,7,8-tetrahydronaphthalene and 2-aminomethyl- 5,6,7,8-tetrahydronaphthalene are known for their cockroach

attracting and ingestion-stimulating activities. p-n-Amyl- phenol, p-n-butylphenol, 5,6,7,8-tetrahydro-l-naphthol and 5,6,7,8-tetrahydro-2-naphthol are known for their cockroach

attracting and ingestion-stimulating activities as described in USP 4,911,907 and USP 4,627,981.

Attracting and ingestion-stimulating agents for cockroach

according to the invention can be prepared, for example, by

dissolving these compounds in an appropriate solvent (for

example, a hydrophilic organic solvent such as acetone,

ethanol, ethanol, tetrahydrofuran, ethylene glycol, diethylene glycol or N,N-dimethy1- formamide or lipophilic

organic solvent such as benzene, chloroform, ether, methylene chloride or n-hexane) then ampergnating an appropriate carrier

(for paper, cardboad, non-woven cloth, or flannel) with the

solution and drying off the solvent to give attracting tapes

or the like. The active-ingredient compounds according to the

invention can also be used in such a form as granule, pill or

tablet prepared by a conventional method using binder,

excipient, lubricant, stabilizer and others as usually

employed to give a bait.

The bait form of the active-ingredient compounds according

to the invention can be formulated together with an

insecticidal ingredient. As the typical examples of the insecticidal ingredient, there can be mentioned,

organophosphorous insecticides such as fenitorothion,

pyridafenthion, chlropyrifos-methyl, pyrethroids such as

allethrin, deltamethrin, phenothrin, resmethrin,

cyphenothrin, permethrin, ethofenprox, fenvalerate,

prallethrin, carbamates such as carbaryl, propoxur,

methoxydiazon, insect growth regulator compounds such as

dodecadienoate compounds, oxime-ether compounds, pyriyl compounds, benzoylphenyl compounds urea and other insecticides

such as hydromethylnon, boric acid etc.

If desired, the cockroach bait may contain one or more .

conventional adjuvants. Examples of conventional adjuvants

include pulverized grain, biscuit powder, sweetening, water, sugar, maltose excipient, excipients, stabirizer, surfactant,

plant oil, dextrin and microcristallin cellulose.

The active ingredient according to the invention show an attracting and ingestion-stimulating activity in a very small

amount so that no particular care should be taken for amount

to be used.

It is preferable, for example, that a bait would contain the

ingredient in a concentration of 0.01 % by weight or more of

whole amount.

The attracting and ingestion-stimulating action of the

agents according to the invention will be described below in detail with reference to test examples.

Test example 1

(Test material)

A test material was prepared by the similar method in

example 5.

The test material contained 0.05% by weight of the

compound in Table 1.

Table 1

(Test insect)

Groups of Periplaneata fuliginosa S. , P.japonica K. , P. australasiae L. , P.americana L. , Blattella germanic L. , Blatta orientalis L. each consisting of 100 adult male and female (1:1) cockroaches were prepared per one test materials.

(Test methods) A group of the test insects was placed individually in a

cage. After three days, the bait of the test material was

examined for the degree of ingestion. The degree of ingestion

of test material(a) - (k) were compared with test material

(1). The experiment was repeated three times, and the average

number of degree of ingestion was taken.

(Test results)

Results are shown in Table 2.

Table 2

These values are expressed as compared with 1.0 of the valure of control sample(l)

Test example 2

(Test materials)

The same test procedure as in Test example 1 were employed

except that two parts of hydromethylnone was formulated as an

insecticide to give a test material (A) - (L).

(Test insects)

As test insects were employed 12 groups of Periplaneata

fuliginosa L. , P.americana L. , Blattella germanic L. , Blatta

orientalis L. consisting of 30 adult cockroaches and 30

larvae cockroaches per one test material.

(Test method)

48 rooms, approximately 6 mats in size, were used. One

week before initiation of the test each room was stocked with

a group of different species of the cockroach, which was given

food and water.

The test material baits were set at five positions in each

room.

Effect of the attractants was evaluated on the basis of the

number of dead cockroach.

(Test results)

The results are shown in Table 3. Table 3

LT90: days within which 90 % mortality

BEST MODE FOR CARRYING OUT THE INVENTION

Some examples of this invention will be explained as the following examples.

However, this invention is not limited to these examples.

Unless otherwise indicated, all parts are by weight.

Example 1

A mixture of 75 parts powdery fish meal, 5 parts of

maltose, 5 parts of L-arabinose, 5 parts of oleic acid, 10

parts of rice brain oil, 0.06 part of permethrin, 0.05 part of

p-n-butylphenol and 0.03 part of 2-amino-5,6,7,8-tetrahydro-

naphthalene was kneaded together with some water, and the

mixture was formed into a small granular bait of the invention

weighing about 0.7 g per granule.

Example 2

150 parts of water-soluble starch, 150 parts of potato

starch, 100 parts of boric acid 0.6 part of sodium benzoate,

0.2 part of dibutylhydroxytoluene, 0.03 part of

2-amino-5,6,7,8-tetrahydro- naphthalene, 0.1 part of 5,6,7,8-

tetrahydro-1-naphthol and 599.5 parts of water were blended

and formed into a cockroach bait of the invention weighing

about 10 g per piece.

Example 3

100 parts of wheat powders, 35 parts of water-soluble starch, 35 parts of starch, one part of methoprene, 0.06 part

of sodium benzoate, 0.02 part of dibutylhydroxytoluene, 0.05

part of 5,6,7,8-tetrahydro-2-naphthol and 0.03 part of

2-amino-5,6,7,8- tetrahydronaphthalene hydrocarbonate were

blended together with an appropriate amount of water and

formed into a cockroach bait of the invention weighing about 5

g per piece.

Example 4

100 parts of corn syrup, 30 parts of sorbitol, 14 parts of gelatin, 48 parts of water, 2 parts of pyriproxyfen, 0.06 part

of sodium benzoate, 0.02 part of dibutylhydroxytoluene,

p-n-butylphenol and 0.1 parts of 2-aminomethyl-5,6,7,8-

tetrahydronaphthalene were blended and formed into a cockroach

bait of the invention weighing about 10 g per piece.

Example 5

40 parts of thick malt syrup, 45 parts of oats powder, 11

parts of macrogol, 0.5 part of cyphenothrin, one part of

diflubenzurone, 0.06 part of sodium benzoate, 0.02 part of

dibutylhydroxytoluene, 0.05 part of p-n-amylphenol and

2-amino-5,6,7,8-tetrahydro- naphthalene were blended and

formed into a.cockroach bait of the invention weighing about

10 g per piece.

Example 6 20 parts of brown sugar, 2 parts of corn oil, 2 parts of

chryslis powder, 20 parts of biscuit powder, 50 parts dextrin, 0.06 part of sodium benzoate, 0.02 part of

dibutylhydroxytoluene, 2 parts of hydramethylnone, 0.02 part

of p-n-amylphenol and 0.03 part of 2-amino-5,6,7,8-tetrahydro-

naphthalene were blended and formed into a cockroach bait of

the invention weighing about 5 g per piece.

Example 7

20 parts of powdery sugar, 10 parts of corn oil, 30 parts

of sweet corn oil, 60 parts of crystalline cellulose, 2 parts

of ethofenprox, 0.06 parts sodium benzoate, 0.02 part of

dibutylhydroxytoluene, 0.02 part of p-n-amylphenol and 0. 03

part of 2-amino-5,6,7,8-tetrahydronaphthalene were blended and

formed into a cockroach bait of the invention weighing about 5

g per piece.

Example 8

15 parts of mineral oil, 2 parts of ammonium hydroxide, 2

parts of polyoxyethylene nonylphenyl ether, 0.5 part of

carboxymethyl cellulose, 3.5 parts of potato starch, one part

of propoxur, 0.5 part of fenoxycarb, 0.06 part of sodium

benozate, 0.02 part of dibutylhydroxytoluene, 0.05 part of

5,6,7,8-tetrahydro-2-naρhthol and 0.03 part of 2-amino-

5,6,7,8-tetrahydronaphthalene were blended and formed into a cockroach bait of the invention weighing about 5 g per piece.

Example 9

15 parts of white mineral oil, 1.5 parts of polyoxyethylene

glycol dioleate, 2 parts of polyoxyethylene nonylphenyl ether,

one part of hydroxyethyl cellulose, 0.5 part of xanthane gum,

5 parts of corn starch, 2 parts of chloropyrifosmethyl, 0.06

part of sodium benzoate, 0.02 part of 5,6,7,8-tetrahydro-

2-naphthol and 0.03 part of 2-amino-5,6,7,8-tetrahydro¬

naphthalene were blended and formed into a cockroach bait of

the invention weighing about 5 g per piece.

INDUSTRIAL APPLICABILITY

The attracting and ingestion-stimulating agents of the

invention not only exhibit a potent attracting and

ingestion-stimulating activity on various species of cockroach

but also are highly effective in cockroach extermination even

when male and female cockroaches live together.

This brings about low production cost and minimize the size

of the preparation for easiness on use.

The attracting and ingestion-stimulating component of the

invention can also provide each of the cockroach controlling

agents with fast acting effect.

Claims

1. An attracting and ingestion-stimulating agent for

cockroach comprising as the active ingredient;

(a) one or more compounds selected from the group of

l-amino-5,6, 7,8-tetrahydronaphthalene, 2-amino-5,6,7,8-

tetrahydronaphthalen , 2-aminomethyl-5,6,7,8-tetrahydro¬

naphthalene and a salt thereof ; and

(b) one or more compounds selected from the group of p-n-

butylphenol, p-n-amylphenol, 5,6,7,8-tetrahydro-l-naphthol and

5,6,7, 8-tetrahydro-2-naphthol.

2. An attracting and ingestion-stimulating agent for

cockroach comprising as the active ingredient one compound

selected from the group consisting of 2-aminomethyl-5,6,7,8-

tetrahydronaphthalene, 1-amino-5,6,7,8-tetrahydronaphthalene, 2-amino-5,6,7,8-tetrahydro-naphthalene and a salt thereof, and

one compound selected from the group consisting of

p-n-amylphenol, p-n-butyIpheno1, 5,6,7,8-tetrahydro-1-naphthol

and 5,6,7,8-tetrahydro-2-naphthol.

3. An attracting and ingestion-stimulating agent to claim 1,

wherein the cockroach is Periplaneata fuliginosa S. ,

P.japonica K.^', P.americana L. , Blattella germanica L. ,

P.australasiae L. or Blatta orientalis L.

4. An attracting and ingestion-stimulating agent to claim 2, wherein the cockroach is Periplaneata fuliginosa L. ,

P.japonica K. , P.americana L. , Blattella germanica L. ,

P.australasiae L. , or Blatta orientalis L.