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ATE6778T1 - Chinazolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Chinazolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE6778T1
ATE6778T1 AT80304335T AT80304335T ATE6778T1 AT E6778 T1 ATE6778 T1 AT E6778T1 AT 80304335 T AT80304335 T AT 80304335T AT 80304335 T AT80304335 T AT 80304335T AT E6778 T1 ATE6778 T1 AT E6778T1
Authority
AT
Austria
Prior art keywords
quinazoline derivatives
carboxy
chem
alkyl
hydrogen
Prior art date
Application number
AT80304335T
Other languages
English (en)
Inventor
Ikuo Ueda
Masayuki Kato
Masanobu Nagano
Original Assignee
Fujisawa Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co., Ltd. filed Critical Fujisawa Pharmaceutical Co., Ltd.
Application granted granted Critical
Publication of ATE6778T1 publication Critical patent/ATE6778T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT80304335T 1979-12-03 1980-12-02 Chinazolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE6778T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7941607 1979-12-03
GB8031965 1980-10-03
EP80304335A EP0030156B1 (de) 1979-12-03 1980-12-02 Chinazolinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE6778T1 true ATE6778T1 (de) 1984-04-15

Family

ID=26273769

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80304335T ATE6778T1 (de) 1979-12-03 1980-12-02 Chinazolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (10)

Country Link
US (2) US4377580A (de)
EP (1) EP0030156B1 (de)
JP (1) JPH0651686B2 (de)
AT (1) ATE6778T1 (de)
AU (1) AU541811B2 (de)
DE (1) DE3067201D1 (de)
DK (1) DK513980A (de)
ES (4) ES8205202A1 (de)
GR (1) GR71637B (de)
IE (1) IE51802B1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
JPS608274A (ja) * 1983-06-27 1985-01-17 Fujisawa Pharmaceut Co Ltd 新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US5420133A (en) * 1993-03-19 1995-05-30 Merck & Co., Inc. Quinazolinones substituted with phenoxyphenylacetic acid derivatives
JP5236293B2 (ja) 2005-01-13 2013-07-17 ブリストル−マイヤーズ スクイブ カンパニー Ｘｉａ因子阻害剤としての置換ビアリール化合物
US9603848B2 (en) * 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US8633186B2 (en) * 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
AU2013202912B2 (en) * 2007-06-08 2016-10-27 Firmenich Incorporated Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) * 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
ES2525551T3 (es) 2008-07-31 2014-12-26 Senomyx, Inc. Composiciones que comprenden potenciadores de dulzor y métodos de producirlas
UA113831C2 (xx) 2008-07-31 2017-03-27 Способи і проміжні сполуки для одержання підсилювачів солодкого смаку
BR112013003332B1 (pt) 2010-08-12 2018-11-13 Senomyx, Inc. método para melhorar a estabilidade de intensificador de doce e composição contendo intensificador de doce estabilizado
KR20150020228A (ko) 2012-05-31 2015-02-25 에프. 호프만-라 로슈 아게 아미노퀴나졸린 및 피리도피리미딘 유도체
BR112015002380B1 (pt) 2012-08-06 2021-09-28 Firmenich Incorporated Composto, composições ingeríveis, processos para aumentar o sabor doce de composição e formulação flavorizante concentrada
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
CN112703193A (zh) 2018-08-07 2021-04-23 弗门尼舍公司 5-取代的4-氨基-1H-苯并[c][1,2,6]噻二嗪2,2-二氧化物及其制剂和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1086666A (en) * 1966-09-12 1967-10-11 Wander Ag Dr A Novel 6-p-tolyl-2,3,6,7-tetrahydro-4h-pyrimido-[1,2-c] quinazoline
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
BE759842R (fr) 1969-12-05 1971-06-03 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
CA986932A (en) * 1970-08-27 1976-04-06 Shigeho Inaba Process for preparing quinazoline derivatives
US4167569A (en) * 1976-12-09 1979-09-11 Imperial Chemical Industries Limited Pyrimido[1,2-a ]benzimidazole derivatives
US4105766A (en) * 1977-08-19 1978-08-08 Sterling Drug Inc. 4,5-Dihydro-5-oxopyrazolo[1,5-a]quinazoline-3-carboxylic acid derivatives
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

Also Published As

Publication number Publication date
ES497426A0 (es) 1982-06-01
US4543356A (en) 1985-09-24
US4377580A (en) 1983-03-22
ES507995A0 (es) 1982-10-01
GR71637B (de) 1983-06-20
JPH05294946A (ja) 1993-11-09
ES8205202A1 (es) 1982-06-01
IE51802B1 (en) 1987-04-01
ES8301234A1 (es) 1982-11-16
DE3067201D1 (en) 1984-04-26
EP0030156A1 (de) 1981-06-10
EP0030156B1 (de) 1984-03-21
JPH0651686B2 (ja) 1994-07-06
ES507994A0 (es) 1982-11-16
AU6473380A (en) 1981-06-11
IE802421L (en) 1981-06-03
AU541811B2 (en) 1985-01-24
ES507996A0 (es) 1982-10-01
ES8207540A1 (es) 1982-10-01
ES8207539A1 (es) 1982-10-01
DK513980A (da) 1981-06-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee