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ATE544461T1 - Rekonstituierte tenside mit verbesserten eigenschaften - Google Patents

Rekonstituierte tenside mit verbesserten eigenschaften

Info

Publication number
ATE544461T1
ATE544461T1 AT08758696T AT08758696T ATE544461T1 AT E544461 T1 ATE544461 T1 AT E544461T1 AT 08758696 T AT08758696 T AT 08758696T AT 08758696 T AT08758696 T AT 08758696T AT E544461 T1 ATE544461 T1 AT E544461T1
Authority
AT
Austria
Prior art keywords
improved properties
directed
amino acid
reconstituted surfactants
polypeptide
Prior art date
Application number
AT08758696T
Other languages
English (en)
Inventor
Jan Johansson
Tore Curstedt
Bengt Robertson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE544461T1 publication Critical patent/ATE544461T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Fire-Extinguishing Compositions (AREA)
AT08758696T 2007-06-01 2008-05-22 Rekonstituierte tenside mit verbesserten eigenschaften ATE544461T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07010857A EP1997502A1 (de) 2007-06-01 2007-06-01 Rekonstituierte Tenside mit verbesserten Eigenschaften
PCT/EP2008/004097 WO2008145298A1 (en) 2007-06-01 2008-05-22 Reconstituted surfactants having improved properties

Publications (1)

Publication Number Publication Date
ATE544461T1 true ATE544461T1 (de) 2012-02-15

Family

ID=38421186

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08758696T ATE544461T1 (de) 2007-06-01 2008-05-22 Rekonstituierte tenside mit verbesserten eigenschaften

Country Status (14)

Country Link
US (1) US7897577B2 (de)
EP (2) EP1997502A1 (de)
JP (1) JP5575639B2 (de)
KR (1) KR101516443B1 (de)
CN (1) CN101687006B (de)
AT (1) ATE544461T1 (de)
AU (1) AU2008256449B2 (de)
BR (1) BRPI0811320A2 (de)
CA (1) CA2689066C (de)
EA (1) EA017697B1 (de)
HK (1) HK1140420A1 (de)
MX (1) MX2009012675A (de)
WO (1) WO2008145298A1 (de)
ZA (1) ZA200908445B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
PT2078038E (pt) 2006-10-13 2013-12-12 Chiesi Farma Spa Agentes tensioativos reconstituídos apresentando propriedades melhoradas
EP2022798A1 (de) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetische Lungensurfactant-Peptide
CA2702094C (en) 2007-10-10 2018-05-01 Parion Sciences, Inc. Delivering osmolytes by nasal cannula
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
US8778383B2 (en) 2011-06-07 2014-07-15 Parion Sciences, Inc. Methods of treatment
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
RS54513B1 (en) 2012-03-28 2016-06-30 Discovery Laboratories, Inc. LYOPHILIZATION OF SYNTHETIC LIPOSOMAL LUNG SURFACTANT
KR102109223B1 (ko) 2012-05-29 2020-05-11 패리온 사이언스 인코퍼레이티드 안구 건조 및 다른 점막 질환의 치료를 위한 나트륨 채널 차단제 활성을 보유하는 덴드리머 유사 아미노 아미드
US9029382B2 (en) 2012-12-17 2015-05-12 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
MX379300B (es) 2012-12-17 2025-03-11 Parion Sciences Inc Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales.
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
MX2017004278A (es) 2014-10-01 2018-03-28 Plant Health Care Inc Peptidos inductores que tienen una caja de respuesta de hipersensibilidad interrumpida y su uso.
WO2016054310A1 (en) 2014-10-01 2016-04-07 Plant Health Care, Inc. Hypersensitive response elicitor peptides and use thereof
US11371011B2 (en) 2016-04-06 2022-06-28 Plant Health Care, Inc. Beneficial microbes for delivery of effector peptides or proteins and use thereof
BR112018070141A2 (pt) 2016-04-06 2019-02-12 Plant Health Care, Inc. resposta hipersensitiva de peptídeos derivados de eliciador e uso dos mesmos
KR102470549B1 (ko) 2016-12-22 2022-11-25 키에시 파르마슈티시 엣스. 피. 에이. 발달하는 bpd의 치료를 위한 폐 계면활성제 및 스테로이드를 포함하는 치료 조합물
MX2020011127A (es) 2018-04-23 2021-01-15 Chiesi Farm Spa Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd).
US20230097886A1 (en) * 2021-07-30 2023-03-30 Ayuvis Research, Inc. Compositions and methods for the treatment of bronchopulmonary dysplasia (bpd) and bpd-associated pulmonary hypertension

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
IT1308180B1 (it) 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
EP1189625A1 (de) * 1999-06-11 2002-03-27 Byk Gulden Lomberg Chemische Fabrik GmbH Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)
KR101036058B1 (ko) * 2002-04-25 2011-05-19 더 스크립스 리서치 인스티튜트 폐질환 증상의 치료 및 예방
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (de) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Neue Lipidmischungen für synthetische Tenside
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
PT2078038E (pt) * 2006-10-13 2013-12-12 Chiesi Farma Spa Agentes tensioativos reconstituídos apresentando propriedades melhoradas
EP2022798A1 (de) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetische Lungensurfactant-Peptide

Also Published As

Publication number Publication date
AU2008256449B2 (en) 2012-09-13
EP1997502A1 (de) 2008-12-03
EA017697B1 (ru) 2013-02-28
ZA200908445B (en) 2011-02-23
AU2008256449A1 (en) 2008-12-04
EA200901459A1 (ru) 2010-06-30
CN101687006B (zh) 2013-10-16
BRPI0811320A2 (pt) 2014-10-21
JP5575639B2 (ja) 2014-08-20
EP2152288B1 (de) 2012-02-08
CN101687006A (zh) 2010-03-31
WO2008145298A1 (en) 2008-12-04
US20090088379A1 (en) 2009-04-02
CA2689066A1 (en) 2008-12-04
EP2152288A1 (de) 2010-02-17
KR20100015802A (ko) 2010-02-12
JP2010528997A (ja) 2010-08-26
HK1140420A1 (en) 2010-10-15
KR101516443B1 (ko) 2015-05-07
US7897577B2 (en) 2011-03-01
CA2689066C (en) 2016-03-29
MX2009012675A (es) 2009-12-14

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