ATE541944T1 - Polynukleotidprimer - Google Patents
PolynukleotidprimerInfo
- Publication number
- ATE541944T1 ATE541944T1 AT06726631T AT06726631T ATE541944T1 AT E541944 T1 ATE541944 T1 AT E541944T1 AT 06726631 T AT06726631 T AT 06726631T AT 06726631 T AT06726631 T AT 06726631T AT E541944 T1 ATE541944 T1 AT E541944T1
- Authority
- AT
- Austria
- Prior art keywords
- polynucleotide primer
- primer
- polynucleotide
- sequence
- nucleotides
- Prior art date
Links
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0506807A GB2424886A (en) | 2005-04-04 | 2005-04-04 | Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations |
PCT/GB2006/001227 WO2006106316A2 (en) | 2005-04-04 | 2006-04-04 | Polynucleotide primers |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE541944T1 true ATE541944T1 (de) | 2012-02-15 |
Family
ID=34586669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06726631T ATE541944T1 (de) | 2005-04-04 | 2006-04-04 | Polynukleotidprimer |
Country Status (6)
Country | Link |
---|---|
US (3) | US9029084B2 (de) |
EP (2) | EP2314717B1 (de) |
JP (1) | JP5761891B2 (de) |
AT (1) | ATE541944T1 (de) |
GB (1) | GB2424886A (de) |
WO (1) | WO2006106316A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009511008A (ja) * | 2005-10-05 | 2009-03-19 | アストラゼネカ ユーケー リミテッド | ErbB受容体薬に対する患者の応答を予測またはモニタリングする方法 |
US8999634B2 (en) * | 2007-04-27 | 2015-04-07 | Quest Diagnostics Investments Incorporated | Nucleic acid detection combining amplification with fragmentation |
GB2453173A (en) * | 2007-09-28 | 2009-04-01 | Dxs Ltd | Polynucleotide primers |
JP2010279264A (ja) * | 2009-06-03 | 2010-12-16 | Tottori Univ | Egfr遺伝子変異検出プライマーセット、それを含むegfr遺伝子変異検出キット、およびそれを用いてegfr遺伝子変異検出を行うための核酸増幅装置 |
CN102234683B (zh) * | 2010-04-23 | 2013-07-17 | 广州益善生物技术有限公司 | 一种egfr基因突变检测液相芯片 |
JP5859274B2 (ja) * | 2010-10-29 | 2016-02-10 | アークレイ株式会社 | Egfr遺伝子の多型検出用プローブ、増幅用プライマーおよびその用途 |
JP5860667B2 (ja) | 2010-10-29 | 2016-02-16 | アークレイ株式会社 | Egfrエクソン21l858r遺伝子多型検出用プライマーセット及びその用途 |
US20120164641A1 (en) * | 2010-12-22 | 2012-06-28 | Roche Molecular Systems, Inc. | Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene |
WO2012157684A1 (ja) * | 2011-05-16 | 2012-11-22 | 地方独立行政法人 大阪府立病院機構 | 血中dnaの定量的検出による悪性新生物の病勢の進行を評価する方法 |
CN103184274A (zh) * | 2011-12-27 | 2013-07-03 | 上海复星医学科技发展有限公司 | 一种ldr技术的egfr突变检测试剂盒 |
CN102747157B (zh) * | 2012-07-16 | 2014-01-22 | 武汉海吉力生物科技有限公司 | 用于检测人类egfr基因突变的引物、探针、试剂盒及检测方法 |
US20140341884A1 (en) * | 2012-12-04 | 2014-11-20 | Roche Molecular Systems, Inc. | Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain |
ES2688840T3 (es) * | 2014-10-09 | 2018-11-07 | F. Hoffmann-La Roche Ag | Mutaciones en el dominio cinasa del receptor del factor de crecimiento epidérmico |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830713A (en) * | 1986-11-04 | 1998-11-03 | Protein Polymer Technologies, Inc. | Methods for preparing synthetic repetitive DNA |
FR2628027B1 (fr) | 1988-03-03 | 1990-07-20 | Hutchinson | Procede de fabrication de pieces de carrosserie d'automobile, notamment d'aileron ou becquet arriere, et pieces obtenues par mise en oeuvre de ce procede |
IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
US5993813A (en) * | 1988-10-19 | 1999-11-30 | The Dow Chemical Company | Family of high affinity, modified antibodies for cancer treatment |
JP2975679B2 (ja) * | 1989-09-08 | 1999-11-10 | ザ・ジョーンズ・ホプキンス・ユニバーシティ | ヒト神経膠腫のegf受容体遺伝子の構造変化 |
US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
WO1994004689A1 (en) * | 1992-08-14 | 1994-03-03 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Recombinant toxin with increased half-life |
DK0706799T3 (da) * | 1994-09-16 | 2002-02-25 | Merck Patent Gmbh | Immunkonjugater II |
US5725493A (en) * | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
US6057156A (en) * | 1997-01-31 | 2000-05-02 | Robozyme Pharmaceuticals, Inc. | Enzymatic nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors |
US20030032090A1 (en) | 1997-05-07 | 2003-02-13 | Schering Corporation, A New Jersey Corporation | Human receptor proteins; related reagents and methods |
US6617438B1 (en) * | 1997-11-05 | 2003-09-09 | Sirna Therapeutics, Inc. | Oligoribonucleotides with enzymatic activity |
US6528640B1 (en) * | 1997-11-05 | 2003-03-04 | Ribozyme Pharmaceuticals, Incorporated | Synthetic ribonucleic acids with RNAse activity |
DE19813317A1 (de) * | 1998-03-26 | 1999-09-30 | Roche Diagnostics Gmbh | Verbessertes Verfahren zur Primer Extension Präamplifikations-PCR |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
US7294482B2 (en) * | 1998-11-19 | 2007-11-13 | Millennium Pharmaceuticals, Inc. | EGF-like nucleic acids |
EP1165758A2 (de) | 1999-04-12 | 2002-01-02 | Ribozyme Pharmaceuticals, Inc. | Regelung der expression von transkiptional-repressorgenen mittels nukleinsäuremolekulen |
AU2001245489A1 (en) * | 2000-03-07 | 2001-09-17 | Whitehead Institute For Biomedical Research | Human single nucleotide polymorphisms |
US6365355B1 (en) * | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
AUPQ909100A0 (en) * | 2000-07-28 | 2000-08-24 | Ludwig Institute For Cancer Research | A method for diagnosis and treatment |
US6444465B1 (en) * | 2000-09-29 | 2002-09-03 | Isis Pharmaceuticals, Inc. | Antinsense modulation of Her-1 expression |
CA2428146A1 (en) * | 2000-11-13 | 2002-05-16 | Universiteit Utrecht | A plant development regulating gene and its uses |
DE60126980T2 (de) * | 2000-11-27 | 2007-11-08 | Praecis Pharmaceuticals Inc., Waltham | Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen |
US7511121B2 (en) * | 2001-03-09 | 2009-03-31 | Arnason Barry G W | Polymeric immunoglobulin fusion proteins that target low-affinity Fcγreceptors |
WO2003070912A2 (en) * | 2001-06-06 | 2003-08-28 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
CA2400601A1 (en) * | 2001-08-31 | 2003-02-28 | University Of Utah Research Foundation | Real-time gene quantification with internal standards |
JP4376629B2 (ja) * | 2002-01-08 | 2009-12-02 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 癌性胸部細胞において差次的に発現された遺伝子産物およびその使用方法 |
WO2004011625A2 (en) | 2002-07-31 | 2004-02-05 | University Of Southern California | Polymorphisms for predicting disease and treatment outcome |
EP1403379A1 (de) | 2002-09-24 | 2004-03-31 | QIAGEN GmbH | Verbesserte Koamplifikation von Nukleinsäuren |
AU2003283966A1 (en) | 2002-09-25 | 2004-04-23 | Pharmacia Corporation | Antisense modulation of farnesoid x receptor expression |
WO2004042054A1 (ja) * | 2002-10-23 | 2004-05-21 | Hubit Genomix, Inc. | 歯周疾患に関連する遺伝的多型 |
WO2004045521A2 (en) * | 2002-11-14 | 2004-06-03 | John Wayne Cancer Institute | Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimaker quantitative rt-pcr |
KR101368446B1 (ko) * | 2004-03-31 | 2014-02-28 | 다나-파버 캔서 인스티튜트 인크. | 암에 걸린 인간 환자의 표피성장인자 수용체 표적 치료의 유효 가능성 결정 방법, 키트, 핵산 프로브, 프라이머쌍 및 단리된 단백질 |
ES2553264T3 (es) * | 2004-05-27 | 2015-12-07 | The Regents Of The University Of Colorado | Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer |
CA2569520C (en) * | 2004-06-04 | 2023-03-14 | Genentech, Inc. | Kras mutations for identifying colorectal tumors responsive to cetuximab or panitumumab |
-
2005
- 2005-04-04 GB GB0506807A patent/GB2424886A/en not_active Withdrawn
-
2006
- 2006-04-04 WO PCT/GB2006/001227 patent/WO2006106316A2/en active Application Filing
- 2006-04-04 EP EP10075695.6A patent/EP2314717B1/de active Active
- 2006-04-04 JP JP2008504838A patent/JP5761891B2/ja active Active
- 2006-04-04 US US11/910,511 patent/US9029084B2/en active Active
- 2006-04-04 EP EP06726631.2A patent/EP1866438B2/de active Active
- 2006-04-04 AT AT06726631T patent/ATE541944T1/de active
-
2013
- 2013-03-12 US US13/796,766 patent/US20130323736A1/en not_active Abandoned
-
2015
- 2015-04-09 US US14/682,620 patent/US20150211076A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1866438B1 (de) | 2012-01-18 |
EP1866438A2 (de) | 2007-12-19 |
US20150211076A1 (en) | 2015-07-30 |
JP2008534025A (ja) | 2008-08-28 |
US9029084B2 (en) | 2015-05-12 |
EP2314717B1 (de) | 2016-08-31 |
WO2006106316A3 (en) | 2007-02-15 |
EP1866438B2 (de) | 2015-12-23 |
GB2424886A (en) | 2006-10-11 |
EP2314717A1 (de) | 2011-04-27 |
WO2006106316A2 (en) | 2006-10-12 |
US20080261219A1 (en) | 2008-10-23 |
US20130323736A1 (en) | 2013-12-05 |
JP5761891B2 (ja) | 2015-08-12 |
GB0506807D0 (en) | 2005-05-11 |
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