ATE538100T1 - Aminotetrahydroindazoloessigsäuren - Google Patents

Aminotetrahydroindazoloessigsäuren

Info

Publication number: ATE538100T1
Authority: AT; Austria
Prior art keywords: compounds; formula; aminotetrahydroindazoloacetic; acids; receptor
Prior art date: 2008-07-15

Application number

AT09780159T

Other languages

English (en)

Inventor

Li Chen

Fariborz Firooznia

Paul Gillespie

Yun He

Tai-An Lin

Sung-Sau So

Hongying Yun

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-15

Filing date

2009-07-06

Publication date

2012-01-15

2009-07-06 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE538100T1 publication Critical patent/ATE538100T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT09780159T 2008-07-15 2009-07-06 Aminotetrahydroindazoloessigsäuren ATE538100T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8070308P	2008-07-15	2008-07-15
PCT/EP2009/058468 WO2010006939A1 (en)	2008-07-15	2009-07-06	Aminotetrahydroindazoloacetic acids

Publications (1)

Publication Number	Publication Date
ATE538100T1 true ATE538100T1 (de)	2012-01-15

Family

ID=41078142

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT09780159T ATE538100T1 (de)	2008-07-15	2009-07-06	Aminotetrahydroindazoloessigsäuren

Country Status (8)

Country	Link
US (2)	US8124641B2 (de)
EP (1)	EP2307382B1 (de)
JP (1)	JP5394487B2 (de)
CN (1)	CN102099342B (de)
AT (1)	ATE538100T1 (de)
CA (1)	CA2728311A1 (de)
ES (1)	ES2378755T3 (de)
WO (1)	WO2010006939A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102099341B (zh) *	2008-07-15	2013-07-10	霍夫曼-拉罗奇有限公司	氨基四氢吲唑基乙酸类
JP5463365B2 (ja) *	2008-11-17	2014-04-09	エフ．ホフマン−ラロシュアーゲー	ナフチル酢酸
US8188090B2 (en) *	2008-11-17	2012-05-29	Hoffman-La Roche Inc.	Naphthylacetic acids
AU2009315713A1 (en) *	2008-11-17	2010-05-20	F. Hoffmann-La Roche Ag	Naphthylacetic acids
ES2545865T3 (es) *	2010-01-27	2015-09-16	Boehringer Ingelheim International Gmbh	Compuestos de pirazol como antagonistas de CRTH2
ES2524079T3 (es)	2010-03-22	2014-12-04	Actelion Pharmaceuticals Ltd.	Derivados de 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9H-carbazol y su uso como moduladores del receptor de prostaglandina D2
EP2457900A1 (de)	2010-11-25	2012-05-30	Almirall, S.A.	Neue Pyrazolderivate mit CRTH2-antagonistischem Verhalten
MX338516B (es)	2011-04-14	2016-04-20	Actelion Pharmaceuticals Ltd	Derivados de acido 7- (heteroaril-amino) -6, 7, 8, 9- tetrahidropirido[1,2-a] indol acetico y sus usos como modulador del receptor de prostaglandina.
FR2974576B1 (fr) *	2011-04-29	2013-07-19	Sanofi Aventis	Derives de n-[(1h-pyrazol-1-yl)aryl]-1h-indole ou 1h- indazole-3-carboxamide, leur preparation et leurs applications en therapeutique
US8470884B2 (en)	2011-11-09	2013-06-25	Hoffmann-La Roche Inc.	Alkenyl naphthylacetic acids
US9000044B2 (en)	2012-02-28	2015-04-07	Hoffmann-La Roche Inc.	Substituted naphthylacetic acids
PT3119779T (pt)	2014-03-17	2018-10-19	Idorsia Pharmaceuticals Ltd	Derivados de ácido azaindol acético e sua utilização como modeladores de recetor d2 de prostaglandina
MX2016011900A (es)	2014-03-18	2016-12-05	Actelion Pharmaceuticals Ltd	Derivados de acido azaindol-acetico y su uso como moduladores del receptor de prostaglandina d2.
EP3350179B1 (de)	2015-09-15	2021-01-13	Idorsia Pharmaceuticals Ltd	Kristalline formen
IT202100003794A1 (it) *	2021-02-18	2022-08-18	Fondazione St Italiano Tecnologia	Metodo per la preparazione di derivati del pirazolo come modulatori della proteina cftr

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3899529A (en) *	1973-02-22	1975-08-12	Merck & Co Inc	Aroyl substituted naphthalene acetic acids
DE3631824A1 (de) *	1986-02-21	1988-03-31	Bayer Ag	Cycloalkano(1.2-b)indol-sulfonamide
DE3623941A1 (de)	1986-07-16	1988-01-28	Bayer Ag	Substituierte amino-5,6,7,8-tetrahydronaphthyl-oxyessigsaeuren, verfahren zu deren herstellung sowie die verwendung als arzneimittel
EP0405602A1 (de)	1989-06-30	1991-01-02	Laboratorios Vinas S.A.	Zinkderivate von antientzündlichen Arzneimitteln mit verbesserter therapeutischer Aktivität
FR2665159B1 (fr)	1990-07-24	1992-11-13	Rhone Poulenc Sante	Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
JP2562405B2 (ja)	1993-04-06	1996-12-11	花王株式会社	ケラチン繊維処理剤組成物
AUPP609198A0 (en)	1998-09-22	1998-10-15	Curtin University Of Technology	Use of non-peptidyl compounds for the treatment of insulin related ailments
WO2003097598A1 (fr)	2002-05-16	2003-11-27	Shionogi & Co., Ltd.	Composé comprenant un antagonisme du récepteur de pdg2
MXPA05013469A (es) *	2003-06-20	2006-03-09	Amgen Inc	Derivados de piperazina y metodos de uso.
US20070232681A1 (en)	2003-10-14	2007-10-04	Oxagen Limited	Compounds Having Crth2 Antagonist Activity
SE0303180D0 (sv)	2003-11-26	2003-11-26	Astrazeneca Ab	Novel compounds
EA014729B1 (ru) *	2004-05-29	2011-02-28	7ТиЭм ФАРМА А/С	Лиганды crth2 рецептора и их применение
US7732618B2 (en)	2004-09-21	2010-06-08	Wyeth	Benzimidazole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof
WO2006036664A1 (en)	2004-09-23	2006-04-06	Amgen Inc.	Substituted sulfonamidopropionamides and methods of use
KR100889185B1 (ko) *	2004-12-21	2009-03-16	에프. 호프만-라 로슈 아게	테트랄린 및 인단 유도체 및 5-ｈｔ 길항제로서의 이의용도
GT200600093A (es)	2005-02-24	2006-10-19		Antagonistas del receptor de pgd2 para el tratamiento de enfermedades inflamatorias
EP2407459A1 (de) *	2005-09-27	2012-01-18	Shionogi & Co., Ltd.	Synthetisches Zwischenprodukt bei der Herstellung eines Sulfonamidderivates mit PGD2-Rezeptor-antagonistischer Wirkung
WO2008123349A1 (ja) *	2007-03-27	2008-10-16	Shionogi & Co., Ltd.	Ｎ－フェニル－ｎ’－フェニルスルホニルピペラジン誘導体の製造方法
US7960567B2 (en) *	2007-05-02	2011-06-14	Amgen Inc.	Compounds and methods useful for treating asthma and allergic inflammation
CN102099341B (zh) *	2008-07-15	2013-07-10	霍夫曼-拉罗奇有限公司	氨基四氢吲唑基乙酸类
CA2734104A1 (en)	2008-08-15	2010-02-18	F. Hoffmann-La Roche Ag	Substituted aminotetralines
WO2010018112A2 (en)	2008-08-15	2010-02-18	F. Hoffmann-La Roche Ag	Monoaryl aminotetralines
JP5463365B2 (ja)	2008-11-17	2014-04-09	エフ．ホフマン−ラロシュアーゲー	ナフチル酢酸
US8188090B2 (en)	2008-11-17	2012-05-29	Hoffman-La Roche Inc.	Naphthylacetic acids

2009
- 2009-07-06 CN CN2009801277080A patent/CN102099342B/zh not_active Expired - Fee Related
- 2009-07-06 US US12/497,786 patent/US8124641B2/en not_active Expired - Fee Related
- 2009-07-06 JP JP2011517853A patent/JP5394487B2/ja not_active Expired - Fee Related
- 2009-07-06 WO PCT/EP2009/058468 patent/WO2010006939A1/en active Application Filing
- 2009-07-06 CA CA2728311A patent/CA2728311A1/en not_active Abandoned
- 2009-07-06 AT AT09780159T patent/ATE538100T1/de active
- 2009-07-06 EP EP09780159A patent/EP2307382B1/de not_active Not-in-force
- 2009-07-06 ES ES09780159T patent/ES2378755T3/es active Active
2011
- 2011-12-13 US US13/324,650 patent/US8268870B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2378755T3 (es)	2012-04-17
US8268870B2 (en)	2012-09-18
CN102099342A (zh)	2011-06-15
JP5394487B2 (ja)	2014-01-22
JP2011528002A (ja)	2011-11-10
CN102099342B (zh)	2013-07-10
US20100016368A1 (en)	2010-01-21
EP2307382A1 (de)	2011-04-13
WO2010006939A1 (en)	2010-01-21
US8124641B2 (en)	2012-02-28
EP2307382B1 (de)	2011-12-21
CA2728311A1 (en)	2010-01-21
US20120095053A1 (en)	2012-04-19

Similar Documents

Publication	Publication Date	Title
ATE538100T1 (de)	2012-01-15	Aminotetrahydroindazoloessigsäuren
WO2010018109A3 (en)	2010-06-10	Substituted aminotetralines
WO2010018112A3 (en)	2010-04-22	Monoaryl aminotetralines
WO2010018113A3 (en)	2010-04-22	Bi-aryl aminotetralines
MX350862B (es)	2017-09-19	Acidos de piperidinil naftilacetico.
AU2018236805B2 (en)	2020-04-09	Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
EA201390934A1 (ru)	2013-11-29	Композиции и способы модулирования fxr
EA201171216A1 (ru)	2012-05-30	Фенилацетат l-орнитина и способы его получения
TN2011000310A1 (en)	2012-12-17	Cyclic pyrimidin-4-carboxamides as ccr2 receptor antagonists for treatment of inflammation, asthma and copd
BR112012018386A2 (pt)	2017-06-20	"inibidores isoindolinona de fosfatidilinositol 3-quinase"
BR112014001801A2 (pt)	2017-02-14	indazóis
EA201690035A1 (ru)	2016-05-31	Новые циклические производные азабензимидазола, используемые в качестве антидиабетических агентов
CA2818187C (en)	2018-10-23	Bromodomain inhibitors and uses thereof
MY157429A (en)	2016-06-15	Trpm8 antagonists and their use in treatments
GB0906579D0 (en)	2009-05-20	Pharmaceuticals, compositions and methods of making and using the same
EA201200423A1 (ru)	2012-08-30	Замещенные фенилуксусные кислоты как dp-2-антагонисты
EA201071320A1 (ru)	2011-06-30	Активаторы глюкокиназы
EA023861B3 (ru)	2016-09-30	Производные пирролидин карбоновой кислоты как агонисты сопряженного с g-белком рецептора 43 (gpr43), фармацевтическая композиция и методы их использования при лечении метаболических нарушений
BR112014023384A8 (pt)	2018-01-16	inibidores de bace espirocíclicos de di-hidro-tiazina e di-hidro-oxazina, e composições e usos dos mesmos.
MX2011006006A (es)	2011-09-08	Compuestos, composicion farmaceutica y metodos para utilizarse en el tratamiento de trastornos metabolicos.
PH12013500301A1 (en)	2013-03-25	Oxadiazole inhibitors of leukotriene production
ECSP11011057A (es)	2011-10-31	Ácidos naftilacéticos
MX2011013032A (es)	2012-02-08	Inhibidores de fosfatidilinositol 3-cinasa.
EA200901474A1 (ru)	2010-04-30	Соли [4-(6-фтор-7-метиламино-2,4-диоксо-1,4-дигидро-2н-хиназолин-3-ил)фенил]-5-хлортиофен-2-илсульфонилмочевины в различных кристаллических формах и фармацевтические композиции на их основе
MX2012000954A (es)	2012-02-28	Composicion far,aceutica topica que incuye la rel-n-[6-[(2r,6s)-2,6-dimetil-4-morfolinil]-3-piridinil]-2-metil- 4'-(trifluoro-metoxi)-[1,1'-bifenil]-3-carboxamida.