[go: up one dir, main page]

ATE528400T1 - Dsrna-bedingte regulation der gen-expression in pflanzen - Google Patents

Dsrna-bedingte regulation der gen-expression in pflanzen

Info

Publication number
ATE528400T1
ATE528400T1 AT04030122T AT04030122T ATE528400T1 AT E528400 T1 ATE528400 T1 AT E528400T1 AT 04030122 T AT04030122 T AT 04030122T AT 04030122 T AT04030122 T AT 04030122T AT E528400 T1 ATE528400 T1 AT E528400T1
Authority
AT
Austria
Prior art keywords
dsrna
plants
gene expression
conditioned
regulation
Prior art date
Application number
AT04030122T
Other languages
English (en)
Inventor
Peter Bernard Heifetz
David Andrew Patton
Joshua Levin
Qiudeng Que
Framond Annick Jeanne De
Martha M Dunn
Jeng Shong Chen
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22188183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE528400(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Application granted granted Critical
Publication of ATE528400T1 publication Critical patent/ATE528400T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT04030122T 1998-05-26 1999-05-25 Dsrna-bedingte regulation der gen-expression in pflanzen ATE528400T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8494298A 1998-05-26 1998-05-26

Publications (1)

Publication Number Publication Date
ATE528400T1 true ATE528400T1 (de) 2011-10-15

Family

ID=22188183

Family Applications (2)

Application Number Title Priority Date Filing Date
AT04030122T ATE528400T1 (de) 1998-05-26 1999-05-25 Dsrna-bedingte regulation der gen-expression in pflanzen
AT99926414T ATE292182T1 (de) 1998-05-26 1999-05-25 Dsrna-bedingte regulation der gen-expression in pflanzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99926414T ATE292182T1 (de) 1998-05-26 1999-05-25 Dsrna-bedingte regulation der gen-expression in pflanzen

Country Status (21)

Country Link
EP (2) EP1080208B1 (de)
JP (2) JP2002516112A (de)
KR (1) KR20010071315A (de)
CN (2) CN101173298B (de)
AR (1) AR020078A1 (de)
AT (2) ATE528400T1 (de)
AU (1) AU751409B2 (de)
BR (1) BR9910729A (de)
CA (1) CA2328058C (de)
CY (1) CY1112420T1 (de)
DE (1) DE69924484T2 (de)
DK (2) DK1080208T3 (de)
ES (2) ES2237107T3 (de)
HU (1) HUP0102103A3 (de)
IL (2) IL139374A0 (de)
MX (1) MXPA00011583A (de)
PL (1) PL344312A1 (de)
PT (1) PT1516931E (de)
TR (1) TR200003481T2 (de)
WO (1) WO1999061631A1 (de)
ZA (1) ZA200006594B (de)

Families Citing this family (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AU743316C (en) 1998-03-20 2005-09-15 Commonwealth Scientific And Industrial Research Organisation Control of gene expression
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
US20040214330A1 (en) 1999-04-07 2004-10-28 Waterhouse Peter Michael Methods and means for obtaining modified phenotypes
US8598332B1 (en) 1998-04-08 2013-12-03 Bayer Cropscience N.V. Methods and means for obtaining modified phenotypes
US7005423B1 (en) 1999-07-02 2006-02-28 Devgen Nv Characterization of gene function using double stranded RNA inhibition
GB9827152D0 (en) * 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
EP1147204A1 (de) * 1999-01-28 2001-10-24 Medical College Of Georgia Research Institute, Inc. Zusammensetzung und verfahren zur in vivo und in vitro abschwächung der genexpression mittels dobbelsträngigem rna
DE19956568A1 (de) * 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
AU2008202208C1 (en) * 1999-01-30 2014-04-24 Alnylam Pharmaceuticals, Inc. Method and medicament for inhibiting the expression of a defined gene
CA2369422A1 (en) * 1999-05-10 2000-11-16 Syngenta Participations Ag Regulation of viral gene expression
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
JP4744049B2 (ja) 1999-08-26 2011-08-10 モンサント・カンパニー 改質したポリ不飽和脂肪酸を有する植物
US7531718B2 (en) 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7067722B2 (en) 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
EP1235842A4 (de) 1999-10-15 2003-04-23 Univ Massachusetts Gene des rns-interferenzweges als hilfsmittel der gezielten gentischen interferenz
GB9925459D0 (en) 1999-10-27 1999-12-29 Plant Bioscience Ltd Gene silencing
US7829693B2 (en) 1999-11-24 2010-11-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
DE10100586C1 (de) 2001-01-09 2002-04-11 Ribopharma Ag Verfahren zur Hemmung der Expression eines Ziegens
US20050229272A1 (en) * 1999-12-30 2005-10-13 Monica Driscoll Compositions and methods for gene silencing
WO2002081628A2 (en) 2001-04-05 2002-10-17 Ribozyme Pharmaceuticals, Incorporated Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies
US7833992B2 (en) 2001-05-18 2010-11-16 Merck Sharpe & Dohme Conjugates and compositions for cellular delivery
US8202979B2 (en) 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
US7491805B2 (en) 2001-05-18 2009-02-17 Sirna Therapeutics, Inc. Conjugates and compositions for cellular delivery
US8273866B2 (en) 2002-02-20 2012-09-25 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
EP1309726B2 (de) 2000-03-30 2018-10-03 Whitehead Institute For Biomedical Research Mediatoren von rns-interferenz, die rns-sequenzspezifisch sind
BR0111839A (pt) * 2000-06-23 2003-09-16 Du Pont Construções recombinantes, método para a redução da expressão de um mrna alvo ou qualquer mrna endógeno substancialmente similar, rna e método para a identificação ou seleção de um gene vegetal essencial
EP1724355A3 (de) 2000-08-30 2007-05-23 North Carolina State University Transgene Pflanzen, die molekulare Decoys enthalten, die den Proteininhalt ändern
AU2001297906B2 (en) 2000-10-31 2007-07-19 Commonwealth Scientific And Industrial Research Organisation Method and means for producing barley yellow dwarf virus resistant cereal plants
WO2002038588A2 (en) 2000-11-07 2002-05-16 North Carolina State University Putrescine-n-methyltransferase promoter
CH695778A5 (de) * 2000-11-29 2006-08-31 Hoffmann La Roche Hemmung der Transkription eines Zielgens in einer Zelle oder in Geweben.
US20040259247A1 (en) 2000-12-01 2004-12-23 Thomas Tuschl Rna interference mediating small rna molecules
AU2002246742B2 (en) * 2000-12-28 2008-02-07 J & J Research Pty Ltd Double-stranded RNA-mediated gene suppression
WO2002059300A2 (en) * 2000-12-28 2002-08-01 J & J Research Pty Ltd Double-stranded rna-mediated gene suppression
US8546143B2 (en) 2001-01-09 2013-10-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
US7423142B2 (en) 2001-01-09 2008-09-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of anti-apoptotic genes
US7767802B2 (en) 2001-01-09 2010-08-03 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of anti-apoptotic genes
WO2002059294A1 (en) 2001-01-26 2002-08-01 Commonwealth Scientific And Industrial Research O Rganisation Methods and means for producing efficient silencing construct using recombinational cloning
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
US7517864B2 (en) 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US20050148530A1 (en) 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US7109165B2 (en) 2001-05-18 2006-09-19 Sirna Therapeutics, Inc. Conjugates and compositions for cellular delivery
SG132542A1 (en) 2001-06-08 2007-06-28 Vector Tobacco Ltd Modifying nicotine and nitrosamine levels in tobacco
ES2192945B1 (es) * 2001-07-06 2005-03-01 Consejo Superior De Investigaciones Cientificas Un metodo para interferir con la infeccion de virus en plantas.
WO2003006477A1 (en) 2001-07-12 2003-01-23 University Of Massachusetts IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
US7745418B2 (en) 2001-10-12 2010-06-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting viral replication
DE10163098B4 (de) 2001-10-12 2005-06-02 Alnylam Europe Ag Verfahren zur Hemmung der Replikation von Viren
DE10202419A1 (de) 2002-01-22 2003-08-07 Ribopharma Ag Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens
US9181551B2 (en) 2002-02-20 2015-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
EP1490489B1 (de) * 2002-03-14 2010-06-02 Commonwealth Scientific and Industrial Research Organisation Verfahren und mittel zur überwachung und modulation des gen-silencing
US7566813B2 (en) 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
BR0308614A (pt) 2002-03-21 2005-02-09 Monsanto Technology Llc Construções de ácidos nucléicos e processos para a produção de composições oleosas de sementes alteradas
US7166771B2 (en) 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
US20040180438A1 (en) 2002-04-26 2004-09-16 Pachuk Catherine J. Methods and compositions for silencing genes without inducing toxicity
JP2005529624A (ja) * 2002-06-21 2005-10-06 シノゲノマックス カンパニー リミテッド ランダムdnaライブラリーと二本鎖rnaライブラリー、その用途および生産方法
AU2003251579B2 (en) * 2002-06-21 2008-04-03 Monsanto Technology Llc Intron double stranded RNA constructs and uses thereof
SI2258847T1 (sl) 2002-08-05 2017-08-31 Silence Therapeutics Gmbh Nadaljnje nove oblike molekul interferenčne RNA
US7923547B2 (en) 2002-09-05 2011-04-12 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US7365186B2 (en) 2002-11-22 2008-04-29 Arborgen, Llc Vascular-preferred promoter sequences and uses thereof
EP2078753A3 (de) 2002-12-26 2010-12-15 Syngenta Participations AG Mit der Zellproliferation zusammenhängende Polypeptide und Verwendungen dafür
EP1639089A4 (de) 2003-06-06 2007-12-12 Arborgen Llc Transkriptionsfaktor
ATE452188T1 (de) 2004-02-10 2010-01-15 Sirna Therapeutics Inc Rna-interferenz-vermittelte hemmung der genexpression unter verwendung multifunktioneller sina (short interfering nucleic acid)
AR047598A1 (es) * 2004-02-10 2006-01-25 Monsanto Technology Llc Semilla de maiz transgenica con mayor contenido de aminoacidos
US7855323B2 (en) 2004-02-10 2010-12-21 Monsanto Technology Llc Recombinant DNA for gene suppression
US7622301B2 (en) 2004-02-24 2009-11-24 Basf Plant Science Gmbh Compositions and methods using RNA interference for control of nematodes
EP2636739B1 (de) 2004-03-12 2014-12-10 Alnylam Pharmaceuticals Inc. iRNA-Wirkstoffe für VEGF-Targeting
EP2308971B1 (de) 2004-04-09 2016-08-17 Monsanto Technology LLC Zusammensetzungen und Verfahren zur Kontrolle von Insektenbefall bei Pflanzen
US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US7453025B2 (en) 2004-09-22 2008-11-18 Arborgen, Llc Reproductive ablation constructs
CN101107362A (zh) 2004-10-21 2008-01-16 文甘扎公司 用于赋予对植物病害生物和植物病原体抗性的方法和材料
US20060150286A1 (en) * 2004-12-23 2006-07-06 Shihshieh Huang Gene suppression in transgenic plants using multiple constructs
EP2003205B1 (de) 2004-12-28 2013-05-01 Pioneer Hi-Bred International, Inc. Verbesserte Kornqualität durch Expressionsveränderung der Saatproteine
ES2429430T3 (es) 2005-01-14 2013-11-14 University Of Guelph Gen y proteína para la detección de azúcares regulados por nitrógeno y modulación de los mismos
EP2338905B1 (de) 2005-02-23 2017-11-29 North Carolina State University Änderung des Alkaloidgehalts von Tabak mittels Modifizierung spezifischer P450-Cytochromgene
AU2006249522A1 (en) 2005-05-25 2006-11-30 Pioneer Hi-Bred International, Inc. Methods for improving crop plant architecture and yield
AU2006287553A1 (en) 2005-09-08 2007-03-15 Chromatin, Inc. Plants modified with mini-chromosomes
EP1941059A4 (de) 2005-10-28 2010-11-03 Alnylam Pharmaceuticals Inc Zusammensetzungen und verfahren zur hemmung der expression des huntingtin-gens
AU2006311725B2 (en) 2005-11-04 2011-11-24 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of NAV1.8 gene
EP1945270B1 (de) 2005-11-09 2011-05-25 Alnylam Pharmaceuticals Inc. Zusammensetzungen und verfahren zur hemmung der expression von faktor v leiden mutationsgen
US8058509B2 (en) 2005-12-21 2011-11-15 Pioneer Hi-Bred International, Inc. Methods and compositions for in planta production of inverted repeats
AU2007205935B2 (en) 2006-01-17 2013-07-11 Synthon Biopharmaceuticals B.V. Compositions and methods for humanization and optimization of N-glycans in plants
US7589257B2 (en) 2006-02-09 2009-09-15 Pioneer Hi-Bred International Inc. Genes for enhancing nitrogen utilization efficiency in crop plants
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
JP5704741B2 (ja) 2006-03-31 2015-04-22 アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. Eg5遺伝子発現の抑制のための組成物および方法
US7557266B2 (en) 2006-04-19 2009-07-07 Pioneer Hi-Bred International, Inc. Isolated polynucleotide molecules corresponding to mutant and wild-type alleles of the maize D9 gene and methods of use
US7691824B2 (en) 2006-04-28 2010-04-06 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a gene from the JC virus
EP2584047B1 (de) 2006-05-11 2014-11-19 Alnylam Pharmaceuticals Inc. Zusammensetzungen und Verfahren zur Hemmung der PCSK9-Genexpression
CN101489566B (zh) 2006-05-19 2012-04-18 阿尔尼拉姆医药品有限公司 Aha基因的RNAi调控及其治疗性应用
WO2007137220A2 (en) 2006-05-22 2007-11-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of ikk-b gene
ES2655700T3 (es) 2006-08-31 2018-02-21 Monsanto Technology, Llc ARN pequeños en fase
CN101528933B (zh) 2006-08-31 2014-10-22 孟山都技术有限公司 快速转化单子叶植物的方法
WO2008036638A2 (en) 2006-09-18 2008-03-27 Alnylam Pharmaceuticals, Inc. Rnai modulation of scap and therapeutic uses thereof
US20090209478A1 (en) 2006-09-21 2009-08-20 Tomoko Nakayama Compositions and methods for inhibiting expression of the hamp gene
WO2008067840A1 (en) 2006-12-08 2008-06-12 Swetree Technologies Ab Plants having improved growth characteristics and method for making the same
PT2129680E (pt) 2007-03-21 2015-08-28 Brookhaven Science Ass Llc Composições combinadas de gancho de cabelo e antissentido e métodos para modulação da expressão
PE20090064A1 (es) 2007-03-26 2009-03-02 Novartis Ag Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende
US7759320B2 (en) 2007-03-29 2010-07-20 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a gene from the Ebola
CA2584934A1 (en) 2007-04-17 2008-10-17 University Of Guelph Nitrogen-regulated sugar sensing gene and protein and modulation thereof
EP2152885B1 (de) 2007-05-23 2014-06-18 Syngenta Participations AG Polynukleotidmarker
WO2008157263A2 (en) 2007-06-15 2008-12-24 Arkansas State University Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
CN101688206B (zh) 2007-07-05 2013-05-15 诺瓦提斯公司 用于治疗病毒感染的dsRNA
CA2695455C (en) 2007-08-14 2019-01-15 Commonwealth Scientific And Industrial Research Organisation Improved gene silencing methods
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US8124851B2 (en) 2007-11-12 2012-02-28 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes
BRPI0819743A2 (pt) 2007-11-20 2014-10-07 Pioneer Hi Bred Int Ácido nucléico isolado, cassete de expressão, célula hospedeira, planta transgênica, semente transgênica, método para modular a resposta de etileno em uma planta, proteína isolada
AU2008335202A1 (en) 2007-12-10 2009-06-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of Factor VII gene
WO2009082208A2 (en) 2007-12-21 2009-07-02 Keygene N.V. Trichome specific promoters
NZ586643A (en) 2007-12-28 2012-10-26 Swetree Technologies Ab Woody plants having improved growth characteristics and method for making the same using transcription factors
KR101397407B1 (ko) 2008-03-05 2014-06-19 알닐람 파마슈티칼스 인코포레이티드 Eg5 및 VEGF 유전자의 발현을 억제하기 위한 조성물 및 방법
US8703921B2 (en) 2008-04-15 2014-04-22 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Compositions and methods for delivering inhibitory oligonucleotides
US8536406B2 (en) 2008-04-28 2013-09-17 Michigan Technological University COMT1 gene fiber-specific promoter elements from poplar
WO2010028054A1 (en) 2008-09-02 2010-03-11 Alnylam Europe Ag. Compositions and methods for inhibiting expression of mutant egfr gene
AU2009296395A1 (en) 2008-09-25 2010-04-01 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene
UY32145A (es) 2008-09-29 2010-04-30 Monsanto Technology Llc Evento transgénico de soja mon87705 y métodos para detectar el mismo
IL302142B2 (en) 2008-10-20 2024-07-01 Alnylam Pharmaceuticals Inc Compounds and methods for inhibiting transthyretin expression
WO2010056519A1 (en) 2008-10-30 2010-05-20 Pioneer Hi-Bred International, Inc. Manipulation of glutamine synthetases (gs) to improve nitrogen use efficiency and grain yield in higher plants
WO2010062240A1 (en) 2008-11-03 2010-06-03 Swetree Technologies Ab Vegetabile material, plants and a method of producing a plant having altered lignin properties
US8431775B2 (en) 2008-12-04 2013-04-30 Pioneer Hi Bred International Inc Methods and compositions for enhanced yield by targeted expression of knotted1
NZ593618A (en) 2008-12-10 2013-02-22 Alnylam Pharmaceuticals Inc Gnaq targeted dsrna compositions and methods for inhibiting expression
US20120041051A1 (en) 2009-02-26 2012-02-16 Kevin Fitzgerald Compositions And Methods For Inhibiting Expression Of MIG-12 Gene
US8716553B2 (en) 2009-03-02 2014-05-06 Pioneer Hi Bred International Inc NAC transcriptional activators involved in abiotic stress tolerance
CA2754043A1 (en) 2009-03-12 2010-09-16 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes
BRPI1014658A2 (pt) 2009-04-14 2019-09-24 Pioneer Hi Bred Int "método para aperfeiçoar a tolerância ao estresse de intrôgenio em uma planta, método para aperfeiçoar a tolerância ao estresse de nitrogênio sob condições com pouco nitrogênio, cassete de expressão, construto, célula vegetal, planta e método de inibição da produção de etileno em uma planta."
BRPI1010843A2 (pt) 2009-06-08 2015-09-08 Nunhems Bv plantas tolerantes à seca
NZ597504A (en) 2009-06-15 2013-10-25 Alnylam Pharmaceuticals Inc Lipid formulated dsrna targeting the pcsk9 gene
US9051567B2 (en) 2009-06-15 2015-06-09 Tekmira Pharmaceuticals Corporation Methods for increasing efficacy of lipid formulated siRNA
EA201200177A1 (ru) 2009-07-24 2012-06-29 Пайонир Хай-Бред Интернэшнл, Инк. Применение связок компонентов домена димеризации для регулирования архитектуры растения
US9029338B2 (en) 2009-08-14 2015-05-12 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus
IN2012DN02408A (de) 2009-10-02 2015-08-21 Pioneer Hi Bred Int
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
TWI412027B (zh) 2009-11-16 2013-10-11 Sony Corp 碟片匣
US9562235B2 (en) 2009-12-06 2017-02-07 A.B. Seeds Ltd. MicroRNA compositions and methods for enhancing plant resistance to abiotic stress
KR101692063B1 (ko) 2009-12-09 2017-01-03 닛토덴코 가부시키가이샤 hsp47 발현의 조절
US20110167517A1 (en) 2010-01-06 2011-07-07 Pioneer Hi-Bred International, Inc. Identification of diurnal rhythms in photosynthetic and non-photsynthetic tissues from zea mays and use in improving crop plants
BR112012022570A2 (pt) 2010-03-08 2015-10-06 Monsato Technology Llc moléculas de polinucleotídeo para regulação de gene em plantas.
WO2011123468A1 (en) 2010-03-29 2011-10-06 Alnylam Pharmaceuticals, Inc. Sirna therapy for transthyretin (ttr) related ocular amyloidosis
JP2013523162A (ja) 2010-04-06 2013-06-17 アルナイラム ファーマシューティカルズ, インコーポレイテッド Cd274/pd−l1遺伝子の発現を阻害するための組成物および方法
CN103220905A (zh) 2010-05-28 2013-07-24 纽海姆有限公司 果实大小增大的植物
US9944671B2 (en) 2010-06-02 2018-04-17 Alnylam Pharmaceuticals, Inc. Compositions and methods directed to treating liver fibrosis
WO2012007945A2 (en) 2010-07-12 2012-01-19 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Isolated polynucleotides and methods and plants using same for regulating plant acidity
DK2632472T3 (en) 2010-10-29 2018-03-19 Sirna Therapeutics Inc RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
CN110123830A (zh) 2010-11-09 2019-08-16 阿尔尼拉姆医药品有限公司 用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法
AU2011338682B2 (en) 2010-12-06 2017-04-27 Quark Pharmaceuticals, Inc. Double stranded oligonucleotide compounds comprising threose modifications
SG192961A1 (en) 2011-03-03 2013-09-30 Quark Pharmaceuticals Inc Compositions and methods for treating lung disease and injury
MX2013010911A (es) 2011-03-23 2015-03-03 Pioneer Hi Bred Int Metodos para producir un locus de rasgo transgenico complejo.
WO2012148835A1 (en) 2011-04-29 2012-11-01 Pioneer Hi-Bred International, Inc. Down-regulation of a homeodomain-leucine zipper i-class homeobox gene for improved plant performance
TWI658830B (zh) 2011-06-08 2019-05-11 日東電工股份有限公司 Hsp47表現調控強化用類視色素脂質體
US10196637B2 (en) 2011-06-08 2019-02-05 Nitto Denko Corporation Retinoid-lipid drug carrier
EP2721160A2 (de) 2011-06-14 2014-04-23 Synthon Biopharmaceuticals B.V. Zusammensetzungen und verfahren zur herstellung und bioabdichtung auxotropher transgener pflanzen
EP2723861A4 (de) 2011-06-21 2014-12-10 Alnylam Pharmaceuticals Inc Zusammensetzungen und verfahren zur hemmung des hepcidin-antimikrobiellen peptids (hamp) oder der damit zusammenhängenden genexpression
US9315813B2 (en) 2011-06-21 2016-04-19 Alnylam Pharmaceuticals, Inc Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes
EP3388068A1 (de) 2011-06-21 2018-10-17 Alnylam Pharmaceuticals, Inc. Zusammensetzung und verfahren zur hemmung der expression von protein-c (proc)-genen
US20140275211A1 (en) 2011-06-21 2014-09-18 Alnylam Pharmaceuticals, Inc. Assays and methods for determining activity of a therapeutic agent in a subject
BR112013033176A2 (pt) 2011-06-21 2018-06-12 E I Du Pont De Nemouras And Company método para produzir uma modificação direcionada em um gene de fertilidade masculina, planta, molécula de ácido nucleio isolada, construto de expressão
US20140235693A1 (en) 2011-06-23 2014-08-21 Alnylam Pharmaceuticals, Inc. Serpina1 sirnas: compositions of matter and methods of treatment
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
CN103957697B (zh) 2011-09-13 2017-10-24 孟山都技术公司 用于杂草控制的方法和组合物
CA2848695A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and composition for weed control comprising inhibiting ppg oxidase
WO2013040057A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
CA2848680C (en) 2011-09-13 2020-05-19 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
CA2853775A1 (en) 2011-10-31 2013-05-10 Pioneer Hi-Bred International, Inc. Improving plant drought tolerance, nitrogen use efficiency and yield
CN103917647B (zh) 2011-11-03 2020-07-10 夸克制药公司 用于神经保护的方法和组合物
UA116097C2 (uk) 2011-12-11 2018-02-12 Зе Стейт Оф Ізраел, Міністрі Оф Агрікалче Енд Руерал Девелопмент, Агрікалчерал Рісьоч Організейшн, (А.Р.О.), Волкані Сентре Спосіб модуляції провідності устячка рослини
US10184131B2 (en) 2012-02-06 2019-01-22 A.B. Seeds Ltd. Isolated polynucleotides expressing or modulating microRNAs or targets of same, transgenic plants comprising same and uses thereof
WO2013138309A1 (en) 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
CN104703998B (zh) 2012-03-13 2020-08-21 先锋国际良种公司 植物中雄性育性的遗传减少
EP2844261B1 (de) 2012-05-02 2018-10-17 Sirna Therapeutics, Inc. Sina-zusammensetzungen
UY34822A (es) 2012-05-24 2013-12-31 Seeds Ltd Ab Composiciones y métodos para silenciar la expresión genética
US10006041B2 (en) 2012-08-16 2018-06-26 Vib Vzw Means and methods for altering the lignin pathway in plants
BR112015008706A2 (pt) 2012-10-18 2018-02-06 Monsanto Technology Llc métodos e composições para controle de praga de plantas
CN103060374B (zh) * 2012-10-30 2014-05-07 中国农业科学院兰州兽医研究所 一种基于位点特异性重组的rna干扰载体及其构建方法和应用
EP3336187A1 (de) 2012-12-05 2018-06-20 Alnylam Pharmaceuticals, Inc. Pcsk9-irna-zusammensetzungen und verfahren zur verwendung davon
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
CN105358695B (zh) 2013-01-01 2019-07-12 A.B.种子有限公司 将dsRNA引入植物种子以调节基因表达的方法
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
EP2951298A1 (de) 2013-01-29 2015-12-09 The University Court of The University Of Glasgow Verfahren und mittels zur erhöhung der stresstoleranz und biomasse in pflanzen
WO2014164014A1 (en) 2013-03-11 2014-10-09 Pioneer Hi-Bred International, Inc. Genes for improving nutrient uptake and abiotic stress tolerance in plants
UA123082C2 (uk) 2013-03-13 2021-02-17 Монсанто Текнолоджи Ллс Спосіб та гербіцидна композиція для боротьби з видами рослин роду sorghum
US20160010101A1 (en) 2013-03-13 2016-01-14 Pioneer Hi-Bred International, Inc. Enhanced nitrate uptake and nitrate translocation by over- expressing maize functional low-affinity nitrate transporters in transgenic maize
WO2014164116A1 (en) 2013-03-13 2014-10-09 Pioneer Hi-Bred International, Inc. Functional expression of bacterial major facilitator superfamily (sfm) gene in maize to improve agronomic traits and grain yield
US10612019B2 (en) 2013-03-13 2020-04-07 Monsanto Technology Llc Methods and compositions for weed control
DK2968424T3 (da) 2013-03-13 2020-03-30 Geneweave Biosciences Inc Ikke-replikative transduktionspartikler og transduktionspartikelbaserede reportersystemer
BR112015023304A2 (pt) 2013-03-14 2017-07-18 Pioneer Hi Bred Int método para melhorar a tolerância ao estresse abiótico de uma planta, planta e semente
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
CA2903555A1 (en) 2013-03-15 2014-09-18 Pioneer Hi-Bred International, Inc. Compositions and methods of use of acc oxidase polynucleotides and polypeptides
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
US10017778B2 (en) 2013-03-21 2018-07-10 Vib Vzw Means and methods for the reduction of photorespiration in crops
US10443063B2 (en) 2013-06-11 2019-10-15 Syngenta Participations Ag Methods for generating transgenic plants
JP6668236B2 (ja) 2013-07-19 2020-03-18 モンサント テクノロジー エルエルシー Leptinotarsa防除用組成物及びその方法
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015066681A1 (en) 2013-11-04 2015-05-07 Monsanto Technology Llc Compositions and methods for controlling arthropod parasite and pest infestations
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
AR099092A1 (es) 2014-01-15 2016-06-29 Monsanto Technology Llc Métodos y composiciones para el control de malezas utilizando polinucleótidos epsps
WO2015116680A1 (en) 2014-01-30 2015-08-06 Two Blades Foundation Plants with enhanced resistance to phytophthora
MX366975B (es) * 2014-03-12 2019-08-01 Univ Sydney Produccion de arn en plantas superiores.
CN106413390B (zh) 2014-04-01 2019-09-27 孟山都技术公司 用于控制虫害的组合物和方法
WO2015171603A1 (en) 2014-05-06 2015-11-12 Two Blades Foundation Methods for producing plants with enhanced resistance to oomycete pathogens
US10988764B2 (en) 2014-06-23 2021-04-27 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
WO2016005449A1 (en) 2014-07-08 2016-01-14 Vib Vzw Means and methods to increase plant yield
US10378012B2 (en) 2014-07-29 2019-08-13 Monsanto Technology Llc Compositions and methods for controlling insect pests
CN107208112A (zh) 2014-11-25 2017-09-26 弗罗里达大学研究基金会有限公司 用于预防或降低细菌和真菌病原体对作物植物的感染的方法和组合物
JP6942632B2 (ja) 2015-01-22 2021-09-29 モンサント テクノロジー エルエルシー Leptinotarsa防除用組成物及びその方法
WO2016196738A1 (en) 2015-06-02 2016-12-08 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
EP3302030A4 (de) 2015-06-03 2019-04-24 Monsanto Technology LLC Verfahren und zusammensetzungen zum einführen von nukleinsäuren in pflanzen
CN114525280A (zh) 2015-09-02 2022-05-24 阿尔尼拉姆医药品有限公司 程序性细胞死亡1配体1(PD-L1)的iRNA组合物及其使用方法
CN108291234A (zh) 2015-09-04 2018-07-17 主基因有限公司 倍数孢子体形成基因
WO2017062790A1 (en) 2015-10-09 2017-04-13 Two Blades Foundation Cold shock protein receptors and methods of use
US12133495B2 (en) 2016-03-18 2024-11-05 Pioneer Hi-Bred International, Inc. Methods and compositions for producing clonal, non-reduced, non-recombined gametes
US11155819B2 (en) 2017-09-07 2021-10-26 Beijing Tide Pharmaceutical Co., Ltd. Double-stranded RNA molecule targeting CKIP-1 and use thereof
CA3148950A1 (en) 2019-07-30 2021-02-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (A.R.O.), Volcani Center Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
US20220290156A1 (en) 2019-08-27 2022-09-15 Sanofi Compositions and methods for inhibiting pcsk9
WO2021100034A1 (en) 2019-11-19 2021-05-27 Protalix Ltd. Removal of constructs from transformed cells
JP2023526328A (ja) 2020-05-14 2023-06-21 エイアールアイズィー・プリシジョン・メディスン・インコーポレイテッド siRNAを使用してPRDM2/RIZタンパク質の発現を調節するがん治療
US20250019717A1 (en) 2021-08-06 2025-01-16 Kws Vegetables B.V. Durable downy mildew resistance in spinach
EP4477069A1 (de) 2023-06-16 2024-12-18 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Nicht reduzierte klonale gametenbildung und entwurf von polyploidem genom bei solanaceae

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217113A (en) 1985-08-07 1988-06-30 Monsanto Co Production of eucaryotic plants which are glyphosate resistant, vectors (transformation and expression), chimeric gene and plant cells
NZ219472A (en) * 1986-03-28 1990-08-28 Calgene Inc Regulation of phenotype in plant cells using dsdna constructs
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
IL89495A (en) 1988-03-08 1995-08-31 Ciba Geigy Ag Chemically regulatable DNA sequence its use for regulating transcription of an associated DNA sequence in plants or plant tissue and its production
EP0342926B1 (de) 1988-05-17 1994-09-28 Mycogen Plant Science, Inc. Pflanzliches Ubiquitinpromotorsystem
EP0392225B1 (de) 1989-03-24 2003-05-28 Syngenta Participations AG Krankheitsresistente transgene Pflanze
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5034323A (en) 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5629183A (en) 1989-05-08 1997-05-13 The United States Of America As Represented By The Secretary Of Agriculture Plant transformation by gene transfer into pollen
US4940935A (en) 1989-08-28 1990-07-10 Ried Ashman Manufacturing Automatic SMD tester
ATE225853T1 (de) 1990-04-12 2002-10-15 Syngenta Participations Ag Gewebe-spezifische promotoren
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5527695A (en) * 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes
GB9320548D0 (en) * 1993-10-06 1993-11-24 Sandoz Ltd Improvements in or relating to organic compounds
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
EP0883682A1 (de) 1996-02-28 1998-12-16 Novartis AG Dns-moleküle, die für pflanzliche protoporphyrinogenoxidasen kodieren; sowie inhibitor-resistente mutanten dazu
GB9710475D0 (en) * 1997-05-21 1997-07-16 Zeneca Ltd Gene silencing
GB9720148D0 (en) * 1997-09-22 1997-11-26 Innes John Centre Innov Ltd Gene silencing materials and methods
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AU743316C (en) * 1998-03-20 2005-09-15 Commonwealth Scientific And Industrial Research Organisation Control of gene expression
CA2325344C (en) * 1998-04-08 2017-12-05 Commonwealth Scientific And Industrial Research Organisation Methods and means for obtaining modified phenotypes

Also Published As

Publication number Publication date
DE69924484D1 (de) 2005-05-04
CA2328058C (en) 2010-10-12
ES2374521T3 (es) 2012-02-17
AU751409B2 (en) 2002-08-15
ES2237107T3 (es) 2005-07-16
IL139374A0 (en) 2001-11-25
CA2328058A1 (en) 1999-12-02
PL344312A1 (en) 2001-10-22
CN1307641A (zh) 2001-08-08
AR020078A1 (es) 2002-04-10
EP1080208A1 (de) 2001-03-07
EP1516931A2 (de) 2005-03-23
CN101173298B (zh) 2013-01-02
AU4368399A (en) 1999-12-13
PT1516931E (pt) 2012-01-11
CN101173298A (zh) 2008-05-07
KR20010071315A (ko) 2001-07-28
DK1080208T3 (da) 2005-07-04
BR9910729A (pt) 2001-02-13
CY1112420T1 (el) 2015-12-09
WO1999061631A1 (en) 1999-12-02
ATE292182T1 (de) 2005-04-15
EP1080208B1 (de) 2005-03-30
JP2002516112A (ja) 2002-06-04
DK1516931T3 (da) 2012-02-06
HUP0102103A3 (en) 2003-03-28
JP2009261403A (ja) 2009-11-12
EP1516931B1 (de) 2011-10-12
ZA200006594B (en) 2002-03-27
MXPA00011583A (es) 2001-05-01
TR200003481T2 (tr) 2001-04-20
DE69924484T2 (de) 2005-09-22
HUP0102103A2 (hu) 2001-09-28
HK1034999A1 (en) 2001-11-09
IL139374A (en) 2011-01-31
EP1516931A3 (de) 2007-10-31

Similar Documents

Publication Publication Date Title
ATE292182T1 (de) Dsrna-bedingte regulation der gen-expression in pflanzen
ATE412752T1 (de) Blattspezifische expression von genen in transgenen pflanzen
NO20010844D0 (no) Regulering av substrataktivitet
ATE506441T1 (de) Pflanzliche expressionsvektoren
DK0991766T3 (da) Regulering af enzymet quinolatphosphoribosyltransferases ekspression
DE59814462D1 (de) Isothiazolcarbonsäureamide und deren Verwendung zum Schutz von Pflanzen
DE69910714D1 (de) Pflanzenaktivierungsmittel
DK0965631T3 (da) Højstabile planteolier
ATE354660T1 (de) Expression von herbizidtoleranzgenen in pflanzenplastiden
DE69810521D1 (de) Abbeizzusammensetzungen, ihre Herstellung und Verwendung
DE69830262D1 (de) Stress-resistente Pflanze
FI972325L (fi) Rekombinaattikonstruktio geeniekspression lisäämiseksi kasveissa
DE69814732D1 (de) Pflanzenwachstumsregulator
FI980092A0 (fi) Regleringsfoerfarande och -anordning i en harvester
DE19780592D2 (de) Ozon-induzierte Genexpression in Pflanzen
DE60040732D1 (de) Expression von sedoheptulose-1,7-bisphosphatase in transgenen pflanzen
DE59902497D1 (de) Pumpfarbwerk
ID26169A (id) Tanaman bersifat perontok daun-sendiri
DE50014817D1 (de) Pflanzen mit veränderter genexpression
SE9701367D0 (sv) Novel plant genes and their use
DE60028751D1 (de) Herbizidresistente pflanzen
ATE256766T1 (de) Eingehauste beizanlage
DK199900134U3 (da) Plantebase
FI4051U1 (fi) Kasvien kasvatusalusta
ID19706A (id) Plant hidro-generator

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1516931

Country of ref document: EP