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ATE521894T1 - Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex - Google Patents

Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex

Info

Publication number
ATE521894T1
ATE521894T1 AT08851789T AT08851789T ATE521894T1 AT E521894 T1 ATE521894 T1 AT E521894T1 AT 08851789 T AT08851789 T AT 08851789T AT 08851789 T AT08851789 T AT 08851789T AT E521894 T1 ATE521894 T1 AT E521894T1
Authority
AT
Austria
Prior art keywords
colorectal cancer
calprotectin
hemoglobin
stool sample
haptoglobin complex
Prior art date
Application number
AT08851789T
Other languages
English (en)
Inventor
Johann Karl
Ursula Garczarek
Norbert Wild
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE521894T1 publication Critical patent/ATE521894T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4727—Calcium binding proteins, e.g. calmodulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805—Haemoglobins; Myoglobins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT08851789T 2007-11-20 2008-11-18 Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex ATE521894T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07022448 2007-11-20
PCT/EP2008/009733 WO2009065551A1 (en) 2007-11-20 2008-11-18 Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex

Publications (1)

Publication Number Publication Date
ATE521894T1 true ATE521894T1 (de) 2011-09-15

Family

ID=40134824

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08851789T ATE521894T1 (de) 2007-11-20 2008-11-18 Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex

Country Status (8)

Country Link
US (2) US20110129860A1 (de)
EP (1) EP2212700B8 (de)
JP (1) JP5227418B2 (de)
CN (1) CN101868729B (de)
AT (1) ATE521894T1 (de)
CA (1) CA2701341C (de)
HK (1) HK1149956A1 (de)
WO (1) WO2009065551A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5700392B2 (ja) * 2010-03-29 2015-04-15 独立行政法人国立高等専門学校機構 生体試料の調製法
ES2380664B2 (es) 2010-10-19 2012-09-13 Certest Biotec, S.L. Método y dispositivo para el diagnóstico rápido de enfermedades en muestras fecales.
GB201021509D0 (en) * 2010-12-20 2011-02-02 Reactivlab Ltd Assay method
CN104178562B (zh) * 2013-05-21 2018-11-09 生物梅里埃股份公司 一种大肠癌预后试剂盒
DK2947459T3 (en) * 2014-05-21 2017-10-23 Bühlmann Laboratories Ag Method for Determining a Protein
MX376501B (es) * 2015-01-30 2025-03-07 Enterome Adn huésped como biomarcador de la enfermedad de crohn.
CN104614371A (zh) * 2015-02-15 2015-05-13 史春龙 一种在便器中检测排泄物生化指标的方法及使用该方法的检测设备
GB2545361B (en) 2015-04-10 2018-01-24 Applied Proteomics Inc Methods of assessing colorectal cancer status
EP3420359B1 (de) * 2016-02-22 2023-04-26 Agency For Science, Technology And Research Verfahren zur detektion haptoglobin mittels oberflächenverstärkter raman-spektroskopie (sers)
SG11201809558PA (en) * 2016-05-30 2018-12-28 Eiken Chemical Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same
CN106814189B (zh) * 2016-12-20 2018-10-26 成都金思唯生物技术有限公司 一种检测艰难梭菌的试剂盒及其用途
CN108333368A (zh) * 2018-02-07 2018-07-27 深圳市伯劳特生物制品有限公司 一种检测人粪便中钙卫蛋白的试剂盒及制备方法
CN112578123B (zh) * 2019-09-27 2022-10-25 成都中医药大学 检测粪钙卫蛋白含量的试剂在制备子宫病变筛查试剂盒中的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198365A (en) * 1987-02-04 1993-03-30 International Immunoassay Laboratories, Inc. Fecal sample immunoassay method testing for hemoglobin
US5455160A (en) * 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
ATE278964T1 (de) * 1996-11-01 2004-10-15 Magne K Fagerhol Verfahren zur proteinextraktion
AUPP713498A0 (en) * 1998-11-17 1998-12-10 Chandler, Howard Milne A method of detecting blood
WO2002080775A1 (en) * 2001-04-04 2002-10-17 Enterix Inc. Method of collecting a gastrointestinal tract sample
JP2004251851A (ja) * 2003-02-21 2004-09-09 Japan Clinical Laboratories Inc 糞便成分の検査方法
EP1724585A1 (de) * 2005-05-21 2006-11-22 ProteoSys AG Annexin für Krebsrisikofeststellung
WO2007071366A1 (en) * 2005-12-21 2007-06-28 Roche Diagnostics Gmbh Method of assessing colorectal cancer by measuring hemoglobin and m2-pk in a stool sample
CN101449163B (zh) * 2006-05-19 2014-06-25 霍夫曼-拉罗奇有限公司 S100a12蛋白作为结肠直肠癌标记的用途
WO2008138522A1 (en) * 2007-05-10 2008-11-20 Roche Diagnostics Gmbh Use of timp-1 as a marker for colorectal cancer

Also Published As

Publication number Publication date
CA2701341C (en) 2012-03-20
CN101868729B (zh) 2013-07-17
CN101868729A (zh) 2010-10-20
JP5227418B2 (ja) 2013-07-03
US20150126401A1 (en) 2015-05-07
CA2701341A1 (en) 2009-05-28
JP2011503593A (ja) 2011-01-27
EP2212700B1 (de) 2011-08-24
EP2212700A1 (de) 2010-08-04
WO2009065551A1 (en) 2009-05-28
EP2212700B8 (de) 2011-10-12
HK1149956A1 (en) 2011-10-21
US20110129860A1 (en) 2011-06-02

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