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ATE505488T1 - Modulator von coagulationskaskaden und fibrinolytischen kaskaden - Google Patents

Modulator von coagulationskaskaden und fibrinolytischen kaskaden

Info

Publication number
ATE505488T1
ATE505488T1 AT06736060T AT06736060T ATE505488T1 AT E505488 T1 ATE505488 T1 AT E505488T1 AT 06736060 T AT06736060 T AT 06736060T AT 06736060 T AT06736060 T AT 06736060T AT E505488 T1 ATE505488 T1 AT E505488T1
Authority
AT
Austria
Prior art keywords
cascades
modulator
fibrinolytic
coagulation
wound
Prior art date
Application number
AT06736060T
Other languages
English (en)
Inventor
James Morrissey
Stephanie Smith
Roberto Docampo
Nicola Mutch
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Application granted granted Critical
Publication of ATE505488T1 publication Critical patent/ATE505488T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06736060T 2005-03-04 2006-02-23 Modulator von coagulationskaskaden und fibrinolytischen kaskaden ATE505488T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65877605P 2005-03-04 2005-03-04
PCT/US2006/006642 WO2006096345A2 (en) 2005-03-04 2006-02-23 Coagulation and fibrinolytic cascades modulator

Publications (1)

Publication Number Publication Date
ATE505488T1 true ATE505488T1 (de) 2011-04-15

Family

ID=36648781

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06736060T ATE505488T1 (de) 2005-03-04 2006-02-23 Modulator von coagulationskaskaden und fibrinolytischen kaskaden

Country Status (8)

Country Link
US (2) US7682808B2 (de)
EP (1) EP1869082B1 (de)
JP (1) JP2008531692A (de)
CN (1) CN101184775A (de)
AT (1) ATE505488T1 (de)
CA (1) CA2600907C (de)
DE (1) DE602006021290D1 (de)
WO (1) WO2006096345A2 (de)

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JP5073270B2 (ja) 2006-11-14 2012-11-14 シスメックス株式会社 凝固検査用試薬及びその製造方法
US20090047366A1 (en) * 2007-08-15 2009-02-19 Bedard Robert L Inorganic Coagulation Accelerators for Individuals taking Platelet Blockers or Anticoagulants
US8821861B2 (en) * 2007-10-05 2014-09-02 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) * 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
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NZ593815A (en) * 2008-12-19 2013-05-31 Tissue factor pathway inhibitor (tfpi) inhibitors and methods of use
EP3260466A1 (de) † 2008-12-22 2017-12-27 Novo Nordisk A/S Anti-tfpi antikörper
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BR112014022435B1 (pt) 2012-03-21 2023-02-14 Takeda Pharmaceutical Company Limited Inibidores de tfpi e métodos de uso
ES2970986T3 (es) 2013-03-08 2024-06-03 Univ California Nanopartículas inorgánicas funcionalizadas con polifosfato como composiciones hemostáticas y métodos de uso
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US9408871B2 (en) * 2013-11-08 2016-08-09 The University Of British Columbia Methods for inhibiting complement activation and uses thereof
US11112145B2 (en) 2014-09-24 2021-09-07 The Board Of Trustees Of The University Of Illinois Artificial platelets for treating catastrophic bleeding
JP7101351B2 (ja) * 2016-04-28 2022-07-15 シスメックス株式会社 血液検体の分析方法、血液検体分析用試薬及び試薬キット、並びに血液検体分析装置
WO2018191582A1 (en) * 2017-04-13 2018-10-18 The Board Of Trustees Of The University Of Illinois Assay for quantifying polyphosphates
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CN111856043A (zh) * 2020-08-28 2020-10-30 保定天岳生物工程有限公司 一种凝血酶原时间检测试剂盒

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Also Published As

Publication number Publication date
US20100143492A1 (en) 2010-06-10
WO2006096345A2 (en) 2006-09-14
WO2006096345A3 (en) 2006-11-30
US7682808B2 (en) 2010-03-23
CA2600907A1 (en) 2006-09-14
US9597375B2 (en) 2017-03-21
EP1869082A2 (de) 2007-12-26
CA2600907C (en) 2016-06-28
CN101184775A (zh) 2008-05-21
DE602006021290D1 (de) 2011-05-26
JP2008531692A (ja) 2008-08-14
EP1869082B1 (de) 2011-04-13
US20060198837A1 (en) 2006-09-07

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