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ATE496884T1 - Sulphonylaminoessigsaeure derivate und deren verwendung als orexin rezeptor antagoniste - Google Patents

Sulphonylaminoessigsaeure derivate und deren verwendung als orexin rezeptor antagoniste

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Publication number
ATE496884T1
ATE496884T1 AT03785607T AT03785607T ATE496884T1 AT E496884 T1 ATE496884 T1 AT E496884T1 AT 03785607 T AT03785607 T AT 03785607T AT 03785607 T AT03785607 T AT 03785607T AT E496884 T1 ATE496884 T1 AT E496884T1
Authority
AT
Austria
Prior art keywords
acid derivatives
receptor antagonists
orexin receptor
sulphonylaminoacetic
preparation
Prior art date
Application number
AT03785607T
Other languages
English (en)
Inventor
Hamed Aissaoui
Martine Clozel
Thomas Weller
Ralf Koberstein
Thierry Sifferlen
Walter Fischli
Original Assignee
Actelion Pharmaceuticals Ltd
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Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
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Publication of ATE496884T1 publication Critical patent/ATE496884T1/de

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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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AT03785607T 2002-10-11 2003-10-06 Sulphonylaminoessigsaeure derivate und deren verwendung als orexin rezeptor antagoniste ATE496884T1 (de)

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US7435815B2 (en) 2008-10-14
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WO2004033418A3 (en) 2004-06-03
MXPA05003295A (es) 2005-07-05
CA2498091C (en) 2011-03-22
EP1554239B1 (de) 2011-01-26
DE60335891D1 (de) 2011-03-10
CN1703397A (zh) 2005-11-30
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US7279578B2 (en) 2007-10-09
EP1554239A2 (de) 2005-07-20
US20060014783A1 (en) 2006-01-19
JP2006502209A (ja) 2006-01-19
BR0315115A (pt) 2005-08-16
NO20051102L (no) 2005-05-04
WO2004033418A2 (en) 2004-04-22
AU2003294671A1 (en) 2004-05-04
RU2005114486A (ru) 2006-01-20

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