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ATE478342T1 - Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren - Google Patents

Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren

Info

Publication number
ATE478342T1
ATE478342T1 AT06836307T AT06836307T ATE478342T1 AT E478342 T1 ATE478342 T1 AT E478342T1 AT 06836307 T AT06836307 T AT 06836307T AT 06836307 T AT06836307 T AT 06836307T AT E478342 T1 ATE478342 T1 AT E478342T1
Authority
AT
Austria
Prior art keywords
compositions
nucleic acids
compact device
purifying nucleic
purifying
Prior art date
Application number
AT06836307T
Other languages
English (en)
Inventor
Tim Quinn
Alan Wirbisky
Der Lught Nick Van
Nate Morken
Rebecca Johnson
Kim Paulsen
Dan Strom
Jim Baldrica
Original Assignee
Qiagen North American Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen North American Holdings filed Critical Qiagen North American Holdings
Application granted granted Critical
Publication of ATE478342T1 publication Critical patent/ATE478342T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06836307T 2005-10-21 2006-10-16 Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren ATE478342T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/255,807 US20070092403A1 (en) 2005-10-21 2005-10-21 Compact apparatus, compositions and methods for purifying nucleic acids
PCT/US2006/040173 WO2007050327A2 (en) 2005-10-21 2006-10-16 Compact apparatus, compositions and methods for purifying nucleic acids

Publications (1)

Publication Number Publication Date
ATE478342T1 true ATE478342T1 (de) 2010-09-15

Family

ID=37836740

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06836307T ATE478342T1 (de) 2005-10-21 2006-10-16 Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren

Country Status (6)

Country Link
US (2) US20070092403A1 (de)
EP (1) EP1955079B1 (de)
JP (1) JP2009512445A (de)
AT (1) ATE478342T1 (de)
DE (1) DE602006016326D1 (de)
WO (1) WO2007050327A2 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7148343B2 (en) * 2001-10-12 2006-12-12 Gentra Systems, Inc. Compositions and methods for using a solid support to purify RNA
US20050032105A1 (en) * 2001-10-12 2005-02-10 Bair Robert Jackson Compositions and methods for using a solid support to purify DNA
US7893228B2 (en) * 2001-10-12 2011-02-22 Qiagen North American Holdings, Inc. Compositions and methods for using a solid support to purify RNA
GB0208642D0 (en) 2002-04-16 2002-05-22 Accentus Plc Metal implants
US7731906B2 (en) 2003-07-31 2010-06-08 Handylab, Inc. Processing particle-containing samples
GB0405680D0 (en) 2004-03-13 2004-04-21 Accentus Plc Metal implants
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
KR20070097430A (ko) * 2004-11-05 2007-10-04 퀴아젠 노쓰 아메리칸 홀딩즈, 인크. 안정화 시약으로부터 핵산을 정제하기 위한 조성물 및 방법
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
EP3088083B1 (de) 2006-03-24 2018-08-01 Handylab, Inc. Methode zur durchführung von pcr mittels einer kartusche mit mehreren bahnen
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US8709787B2 (en) 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
US20080131500A1 (en) * 2006-12-04 2008-06-05 The Board Of Regents Of The University Of Texas System Methods and compositions for rapid inactivation of proteins
EP1947463A1 (de) * 2007-01-16 2008-07-23 Roche Diagnostics GmbH Entnahme von flüssigen Analyseproben zum Zweck der klinischen Analyse
CA2692186C (en) * 2007-06-29 2019-03-12 Becton, Dickinson And Company Methods for extraction and purification of components of biological samples
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
JP5651011B2 (ja) 2007-07-13 2015-01-07 ハンディーラブ インコーポレイテッド ポリヌクレオチド捕捉材料およびその使用方法
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
KR101443218B1 (ko) * 2007-08-16 2014-09-24 삼성전자주식회사 코스모트로픽 염을 이용한 고체 지지체에서의 rna 정제방법
US20090053704A1 (en) * 2007-08-24 2009-02-26 Natalia Novoradovskaya Stabilization of nucleic acids on solid supports
CN101918621B (zh) 2007-10-03 2012-08-15 阿山特斯有限公司 制造具有杀生物性能的金属的方法
KR101432034B1 (ko) * 2007-11-16 2014-08-21 삼성전자주식회사 코스모트로픽 염을 이용한 고체 지지체에서의 작은 rna분리 방법
ES2574129T3 (es) * 2008-04-02 2016-06-15 Rbc Bioscience Corp. Reactivos, agentes caotrópicos, kits y métodos para aislar ácidos nucleicos basados en materiales de celulosa magnéticos
US20110009608A1 (en) * 2008-04-09 2011-01-13 Bioneer Corporation Automatic refining apparatus, multi-well plate kit and method for extracting hexane from biological samples
KR101025135B1 (ko) 2008-04-09 2011-03-31 (주)바이오니아 자동정제장치, 멀티 웰 플레이트 키트 및 생물학적 시료로부터 핵산을 추출하는 방법
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US10094485B2 (en) 2008-07-18 2018-10-09 Flowserve Management Company Variable-speed actuator
US9188237B2 (en) 2008-07-18 2015-11-17 Flowserve Management Company Variable-speed actuator
WO2010088517A1 (en) * 2009-01-30 2010-08-05 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Methods and systems for purifying transferring and/or manipulating nucleic acids
US20130030165A1 (en) 2010-04-08 2013-01-31 Qiagen Gmbh Chromatographic device and method for isolating and purifying nucleic acids
EP2556143B1 (de) 2010-04-08 2016-12-07 Qiagen GmbH Verfahren zum isolieren und reinigen von nukleinsäuren
EP2395082A1 (de) 2010-06-14 2011-12-14 QIAGEN GmbH Extraktion von Nukleinsäuren aus in Wachs eingebetteten Proben
KR101400675B1 (ko) 2010-11-18 2014-05-29 (주)바이오니아 에어로졸방지를 위한 자동정제장비 및 자동정제방법
EP2681567B1 (de) 2011-03-03 2021-04-28 Life Technologies Corporation Probenahmesonden
ES2617599T3 (es) 2011-04-15 2017-06-19 Becton, Dickinson And Company Termociclador microfluídico de exploración en tiempo real y métodos para termociclado sincronizado y detección óptica de exploración
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
KR102121853B1 (ko) 2011-09-30 2020-06-12 벡톤 디킨슨 앤드 컴퍼니 일체화된 시약 스트립
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
CN102514874B (zh) * 2011-12-29 2013-09-25 协鑫动力新材料(盐城)有限公司 一种组合式电池转移装置
BR112014018995B1 (pt) 2012-02-03 2021-01-19 Becton, Dickson And Company sistemas para executar ensaio automatizado
CN103013814B (zh) * 2012-12-20 2014-07-02 嘉兴凯实生物科技有限公司 一种核酸纯化装置
RU2654666C2 (ru) * 2013-05-24 2018-05-21 Оккам Байолэбс, Инк. Система и способ сбора образца нуклеиновой кислоты
WO2015154189A1 (en) * 2014-04-10 2015-10-15 Dna Genotek Inc. Method and system for microbial lysis using periodates
WO2015192328A1 (zh) * 2014-06-17 2015-12-23 深圳迈瑞生物医疗电子股份有限公司 提取物分离装置及其工作方法
RU2020124757A (ru) 2014-11-21 2021-06-30 Оккам Байолэбс, Инк. Система и способ сбора образца нуклеиновой кислоты
CN108027379B (zh) 2015-06-26 2021-07-23 雅培实验室 用于诊断分析设备的反应容器交换装置
JP6747455B2 (ja) * 2016-01-29 2020-08-26 コニカミノルタ株式会社 検出方法、検出システム、および検出装置
JP6771903B2 (ja) 2016-02-29 2020-10-21 シスメックス株式会社 検体前処理装置、検体前処理カートリッジおよび検体前処理方法
EP3213819B1 (de) * 2016-03-02 2021-09-29 F. Hoffmann-La Roche AG Vorrichtung und methode zur trennung
CN107345199A (zh) * 2016-05-05 2017-11-14 王磊 生物样品制备系统
KR102256775B1 (ko) * 2016-09-29 2021-05-27 (주)바이오니아 생물학적 시료 처리장치
WO2019017726A2 (en) * 2017-07-21 2019-01-24 Seegene, Inc. MAGNETIC BALL TRANSFER MODULES, AUTOMATED SYSTEM COMPRISING SAME, AND PROCESS FOR EXTRACTING NUCLEIC ACIDS USING THE SAME
EP3679350A4 (de) * 2017-09-05 2021-10-20 George Mismas Probenvorbereitungsvorrichtung
EP3470141B1 (de) * 2017-10-11 2024-04-24 F. Hoffmann-La Roche AG Vorrichtung und verfahren zur verarbeitung einer biologischen probe mit magnetischen partikeln
KR102066119B1 (ko) * 2018-02-09 2020-02-17 제노플랜코리아 주식회사 다중 분석을 수행하기 위한 분주 매핑 장치 및 그 동작 방법
CA3103268A1 (en) * 2018-06-28 2020-01-02 Gen-Probe Incorporated Sample preparation method and system
CN111100860A (zh) * 2018-10-26 2020-05-05 南京金斯瑞生物科技有限公司 一种大规模磁力纯化系统
CN110819623A (zh) * 2019-11-08 2020-02-21 珠海迪尔生物工程有限公司 核酸提取仪及提取方法
CN110699429B (zh) * 2019-11-25 2023-04-07 宁波艾捷康宁生物科技有限公司 一种尿液dna提取保存液、尿液保存管、提取试剂盒和提取方法
CN216550412U (zh) * 2019-12-13 2022-05-17 贝克顿·迪金森公司 用于分析核酸的系统
CN111172240A (zh) * 2020-03-06 2020-05-19 苏州博方生物技术有限公司 一种核酸释放剂及hpv病毒核酸检测试剂盒
CN112834298B (zh) * 2020-12-30 2022-01-28 山西大学 一种防污染样本处理系统

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56119254A (en) * 1980-02-25 1981-09-18 Takeda Chemical Industries Ltd Rubber stopper for vial
US4508625A (en) * 1982-10-18 1985-04-02 Graham Marshall D Magnetic separation using chelated magnetic ions
US5523231A (en) * 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
DE69126690T2 (de) * 1990-04-06 1998-01-02 Perkin Elmer Corp Automatisiertes labor für molekularbiologie
DK74692D0 (da) * 1992-06-03 1992-06-03 Foss Electric As Apparat
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
US5342581A (en) * 1993-04-19 1994-08-30 Sanadi Ashok R Apparatus for preventing cross-contamination of multi-well test plates
US6258325B1 (en) * 1993-04-19 2001-07-10 Ashok Ramesh Sanadi Method and apparatus for preventing cross-contamination of multi-well test plates
US20030127396A1 (en) * 1995-02-21 2003-07-10 Siddiqi Iqbal Waheed Apparatus and method for processing magnetic particles
EP2259070A3 (de) * 1995-07-31 2011-03-30 Precision System Science Co., Ltd. Gefäss
JP3927570B2 (ja) * 1995-07-31 2007-06-13 プレシジョン・システム・サイエンス株式会社 容器
US5973137A (en) * 1996-02-13 1999-10-26 Gentra Systems, Inc. Low pH RNA isolation reagents, method, and kit
US5863801A (en) * 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US5885529A (en) * 1996-06-28 1999-03-23 Dpc Cirrus, Inc. Automated immunoassay analyzer
AU3651497A (en) * 1996-07-05 1998-02-02 Beckman Coulter, Inc. Automated sample processing system
EP0818461B1 (de) * 1996-07-12 2005-09-28 Toyo Boseki Kabushiki Kaisha Verfahren zur Isolierung von Ribonucleinsäuren.
US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
JP2001516731A (ja) * 1997-09-17 2001-10-02 ジエントラ・システムズ・インコーポレーテツド 核酸を単離するための装置および方法
ATE423622T1 (de) * 1998-05-01 2009-03-15 Gen Probe Inc Automatisches isolierungs- und amplifizierungsverfahren für eine zielnukleinsäuresequenz
DE19856064C2 (de) * 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
US6716396B1 (en) * 1999-05-14 2004-04-06 Gen-Probe Incorporated Penetrable cap
NL1012996C2 (nl) * 1999-09-08 2001-03-12 Micronic B V Afsluitmat voor het afsluiten van reageerbuizen.
US6455005B1 (en) * 2000-02-02 2002-09-24 Soltec, Inc. Flexible septa closure plug mats for well plate mounted arrays of sample vials
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
US20020054833A1 (en) * 2000-05-26 2002-05-09 Daqing Qu Use of membrane cover in prevention of cross-contamination in multiple biological material isolation processing
GB0013658D0 (en) * 2000-06-05 2000-07-26 Dynal Asa Nucleic acid isolation
US7070740B1 (en) * 2000-09-28 2006-07-04 Beckman Coulter, Inc. Method and apparatus for processing biomolecule arrays
DE10063984A1 (de) * 2000-12-19 2002-06-20 Bilatec Ges Zur Entwicklung Bi Vorrichtungen zur magnetischen Abtrennung von Magnetpartikeln
US6893612B2 (en) * 2001-03-09 2005-05-17 Gen-Probe Incorporated Penetrable cap
US6739478B2 (en) * 2001-06-29 2004-05-25 Scientific Products & Systems Llc Precision fluid dispensing system
US20050032105A1 (en) * 2001-10-12 2005-02-10 Bair Robert Jackson Compositions and methods for using a solid support to purify DNA
US7893228B2 (en) * 2001-10-12 2011-02-22 Qiagen North American Holdings, Inc. Compositions and methods for using a solid support to purify RNA
US7148343B2 (en) * 2001-10-12 2006-12-12 Gentra Systems, Inc. Compositions and methods for using a solid support to purify RNA
EP1438426A1 (de) * 2001-10-12 2004-07-21 Gentra Systems Inc. Zusammensetzungen und verfahren für die verwendung einer festen phase bei der aufreinigung von rna
JP2005511066A (ja) * 2001-12-07 2005-04-28 ダイアックス、コープ 磁気応答性粒子を洗浄する方法及び装置
US20040197780A1 (en) * 2003-04-02 2004-10-07 Agencourt Bioscience Corporation Method for isolating nucleic acids
US20050009036A1 (en) * 2003-07-11 2005-01-13 Applera Corporation Methods and kits for obtaining nucleic acid from biological samples
JP4284250B2 (ja) * 2003-09-09 2009-06-24 富士フイルム株式会社 核酸分離精製方法
EP1664295A4 (de) * 2003-09-09 2007-12-05 Fujifilm Corp Verfahren zur isolierung und reinigung einer nukleinsäure
ATE466080T1 (de) * 2003-12-16 2010-05-15 Qiagen North American Holdings Formulierungen und verfahren zum denaturieren von proteinen
JP2005272397A (ja) * 2004-03-25 2005-10-06 Fuji Photo Film Co Ltd 核酸の分離精製方法
KR20070097430A (ko) * 2004-11-05 2007-10-04 퀴아젠 노쓰 아메리칸 홀딩즈, 인크. 안정화 시약으로부터 핵산을 정제하기 위한 조성물 및 방법

Also Published As

Publication number Publication date
EP1955079B1 (de) 2010-08-18
US20070092403A1 (en) 2007-04-26
DE602006016326D1 (de) 2010-09-30
US20120058011A1 (en) 2012-03-08
WO2007050327A2 (en) 2007-05-03
JP2009512445A (ja) 2009-03-26
WO2007050327A3 (en) 2007-08-09
EP1955079A2 (de) 2008-08-13

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