ATE475706T1 - Abgeschwächter dengue-serotyp-2-stamm - Google Patents

Abgeschwächter dengue-serotyp-2-stamm

Info

Publication number: ATE475706T1
Authority: AT; Austria
Prior art keywords: strain; dengue serotype; attenuated dengue; attenuated; serotype
Prior art date: 2005-06-17

Application number

AT06755943T

Other languages

English (en)

Inventor

Richard Kinney

Claire Huang

Veronique Barban

Jean Lang

Bruno Guy

Original Assignee

Sanofi Pasteur

Ct S For Disease Control And P

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-06-17

Filing date

2006-06-07

Publication date

2010-08-15

2006-06-07 Application filed by Sanofi Pasteur, Ct S For Disease Control And P filed Critical Sanofi Pasteur

2010-08-15 Application granted granted Critical

2010-08-15 Publication of ATE475706T1 publication Critical patent/ATE475706T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/08—Inactivation or attenuation by serial passage of virus
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24164—Methods of inactivation or attenuation by serial passage
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

AT06755943T 2005-06-17 2006-06-07 Abgeschwächter dengue-serotyp-2-stamm ATE475706T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69127405P	2005-06-17	2005-06-17
PCT/IB2006/001513 WO2006134443A1 (en)	2005-06-17	2006-06-07	Dengue serotype 2 attenuated strain

Publications (1)

Publication Number	Publication Date
ATE475706T1 true ATE475706T1 (de)	2010-08-15

Family

ID=37103341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06755943T ATE475706T1 (de)	2005-06-17	2006-06-07	Abgeschwächter dengue-serotyp-2-stamm

Country Status (18)

Country	Link
US (4)	US7641908B2 (de)
EP (1)	EP1891210B1 (de)
JP (1)	JP5075120B2 (de)
KR (2)	KR20080018271A (de)
CN (1)	CN101238209B (de)
AR (1)	AR053914A1 (de)
AT (1)	ATE475706T1 (de)
AU (1)	AU2006257621B2 (de)
BR (1)	BRPI0613287A2 (de)
CA (1)	CA2611954C (de)
DE (1)	DE602006015807D1 (de)
IL (1)	IL188068A0 (de)
MX (1)	MX2007015872A (de)
MY (2)	MY161457A (de)
NO (1)	NO20076360L (de)
TW (1)	TWI375722B (de)
WO (1)	WO2006134443A1 (de)
ZA (1)	ZA200710752B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006134443A1 (en) *	2005-06-17	2006-12-21	Sanofi Pasteur	Dengue serotype 2 attenuated strain
CU23586A1 (es) *	2005-11-22	2010-10-30	Ct Ingenieria Genetica Biotech	Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus
FR2903605A1 (fr) *	2006-07-12	2008-01-18	Sanofi Pasteur Sa	Methode d'immunisation contre les quatres serotypes de la dengue
FR2909286B1 (fr) *	2006-12-01	2012-06-08	Sanofi Pasteur	Methode d'immunisation contre les 4 serotypes de la dengue
CN101139638B (zh) *	2007-05-08	2010-05-26	深圳太太基因工程有限公司	一种用于检测登革病毒ⅲ型核苷酸片段的引物和探针序列
BRPI0909820A2 (pt)	2008-03-05	2015-08-11	Sanofi Pasteur	Processo para estabilização de composição de vacina contra gripe, para estabilização de composição de vacina contendo adjuvante e para preparação de vacina, composições de vacina, kit de vacina e método de estocagem de uma matéria prima
EP2143440A1 (de)	2008-07-09	2010-01-13	Sanofi Pasteur	Stabilisierungssubstanz und Impfzusammensetzung, die ein oder mehrere abgeschwächte lebende Flaviviridae enthält
US8968996B2 (en) *	2009-06-01	2015-03-03	Takeda Vaccines, Inc.	Compositions and methods for rapid immunization against dengue virus
WO2010141386A1 (en) *	2009-06-01	2010-12-09	Inviragen, Inc.	Compositions and methods for administration of vaccines against dengue virus
EP2473624B1 (de)	2009-08-31	2019-05-01	Gen-Probe Incorporated	Test für dengue-virus
CN102755642B (zh) *	2012-07-13	2014-01-08	中国食品药品检定研究院	一种炭疽疫苗的制备方法
CA2878682A1 (en)	2012-07-24	2014-01-30	Alain Bouckenooghe	Vaccine compositions for use in a method of protecting a human subject against dengue disease
CN104812408A (zh) *	2012-07-24	2015-07-29	赛诺菲巴斯德有限公司	用于防止登革热病毒感染的疫苗组合物
WO2014083194A1 (en)	2012-11-30	2014-06-05	Sanofi Pasteur	Methods for inducing antibodies
EP2931310A4 (de)	2012-12-14	2016-05-25	Takeda Vaccines Inc	Zusammensetzungen, verfahren zur verabreichung und verwendungen für dreiwertige dengue-virus-formulierungen
EP4183411A1 (de) *	2013-03-15	2023-05-24	Takeda Vaccines, Inc.	Zusammensetzungen und verfahren für chimäre dengue-virus-konstrukte in impfstoffen
KR20160023683A (ko)	2013-06-21	2016-03-03	머크 샤프 앤드 돔 코포레이션	뎅기 바이러스 백신 조성물 및 그의 사용 방법
CN103382509A (zh) *	2013-07-17	2013-11-06	浙江国际旅行卫生保健中心	逆转录-环介导等温扩增检测登革2型病毒的试剂及检测方法
TWI852899B (zh)	2014-09-02	2024-08-21	法商賽諾菲巴斯德公司	疫苗組合物
EP3236997B1 (de)	2014-12-22	2024-05-29	Merck Sharp & Dohme LLC	Dengue-virus-impfstoffzusammensetzungen und verfahren zur verwendung davon
EP3316905A1 (de)	2015-07-03	2018-05-09	Sanofi Pasteur	Gleichzeitige impfung gegen dengue und gelbfieber
SG11201804317YA (en)	2015-11-27	2018-06-28	The Chemo Sero Therapeutic Res Institute	Live virus having a bank of dengue virus attenuated strains, and a dengue vaccine containing same as antigens
CN105999260B (zh) *	2016-05-13	2019-12-10	四川大学	氢氧化铝凝胶-氯化钠复合免疫佐剂及其制备方法和用途
WO2019069130A1 (en)	2017-10-05	2019-04-11	Sanofi Pasteur	COMPOSITIONS FOR RECALL VACCINATION AGAINST DENGUE
US11426461B2 (en)	2018-09-05	2022-08-30	Takeda Vaccines, Inc.	Methods for preventing dengue and hepatitis A
PE20211545A1 (es)	2018-09-05	2021-08-16	Takeda Vaccines Inc	Dosis unitaria de vacuna contra el dengue y administracion de esta
US11464815B2 (en)	2018-09-05	2022-10-11	Takeda Vaccines, Inc.	Dengue vaccine unit dose and administration thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6093296A (en) *	1995-06-07	1996-12-30	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	Infectious dengue 2 virus pdk-53 as quadravalent vaccine
ES2322327T3 (es) *	1999-03-26	2009-06-19	Walter Reed Army Institute Of Research	Vacuna multivalente contra el virus del dengue.
DK1159968T3 (da) *	2000-05-30	2009-02-23	Univ Mahidol	Attenuerede stammer af Dengue-virus og deres anvendelse i en vaccinesammensætning
AU2002223560B2 (en) *	2000-09-25	2006-06-29	Polymun Scientific Immunbiologische Forschung Gmbh	Live influenza vaccine and method of manufacture
AU2002312011B2 (en) *	2001-05-22	2008-04-24	The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses
PT1554301E (pt) *	2002-05-03	2010-12-28	Us Health	Vacina tetravalente contra a dengue contendo uma deleção comum de 30 nucleótidos na 3¿-utr da dengue de tipos 1, 2, 3 e 4 ou vírus quiméricos antigénicos da dengue 1, 2, 3 e 4
WO2006134443A1 (en) *	2005-06-17	2006-12-21	Sanofi Pasteur	Dengue serotype 2 attenuated strain

2006
- 2006-06-07 WO PCT/IB2006/001513 patent/WO2006134443A1/en active Application Filing
- 2006-06-07 CN CN2006800285156A patent/CN101238209B/zh not_active Expired - Fee Related
- 2006-06-07 JP JP2008516431A patent/JP5075120B2/ja not_active Expired - Fee Related
- 2006-06-07 MX MX2007015872A patent/MX2007015872A/es active IP Right Grant
- 2006-06-07 KR KR1020087001413A patent/KR20080018271A/ko active IP Right Grant
- 2006-06-07 KR KR1020147001614A patent/KR101582163B1/ko not_active IP Right Cessation
- 2006-06-07 AU AU2006257621A patent/AU2006257621B2/en not_active Ceased
- 2006-06-07 CA CA2611954A patent/CA2611954C/en not_active Expired - Fee Related
- 2006-06-07 BR BRPI0613287-1A patent/BRPI0613287A2/pt not_active IP Right Cessation
- 2006-06-07 AT AT06755943T patent/ATE475706T1/de not_active IP Right Cessation
- 2006-06-07 EP EP06755943A patent/EP1891210B1/de active Active
- 2006-06-07 DE DE602006015807T patent/DE602006015807D1/de active Active
- 2006-06-14 MY MYPI2011006054A patent/MY161457A/en unknown
- 2006-06-14 MY MYPI20062801A patent/MY144542A/en unknown
- 2006-06-15 US US11/453,344 patent/US7641908B2/en active Active
- 2006-06-16 AR ARP060102567A patent/AR053914A1/es unknown
- 2006-06-16 TW TW095121611A patent/TWI375722B/zh not_active IP Right Cessation
2007
- 2007-12-11 ZA ZA200710752A patent/ZA200710752B/xx unknown
- 2007-12-12 IL IL188068A patent/IL188068A0/en not_active IP Right Cessation
- 2007-12-12 NO NO20076360A patent/NO20076360L/no not_active Application Discontinuation
2009
- 2009-12-08 US US12/633,459 patent/US8067566B2/en active Active
2011
- 2011-10-25 US US13/281,255 patent/US8795688B2/en active Active
2014
- 2014-08-04 US US14/450,529 patent/US20150031857A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1891210B1 (de)	2010-07-28
US20070026016A1 (en)	2007-02-01
US8795688B2 (en)	2014-08-05
AU2006257621B2 (en)	2011-08-11
AR053914A1 (es)	2007-05-23
WO2006134443A1 (en)	2006-12-21
MX2007015872A (es)	2008-04-21
BRPI0613287A2 (pt)	2010-12-28
CA2611954A1 (en)	2006-12-21
AU2006257621A1 (en)	2006-12-21
ZA200710752B (en)	2008-12-31
NO20076360L (no)	2008-03-11
IL188068A0 (en)	2008-03-20
KR20140019034A (ko)	2014-02-13
US7641908B2 (en)	2010-01-05
CN101238209B (zh)	2013-02-13
DE602006015807D1 (de)	2010-09-09
TW200738881A (en)	2007-10-16
CN101238209A (zh)	2008-08-06
EP1891210A1 (de)	2008-02-27
MY144542A (en)	2011-09-30
KR101582163B1 (ko)	2016-01-05
US20150031857A1 (en)	2015-01-29
TWI375722B (en)	2012-11-01
CA2611954C (en)	2014-01-28
US8067566B2 (en)	2011-11-29
US20100174057A1 (en)	2010-07-08
KR20080018271A (ko)	2008-02-27
JP2008546383A (ja)	2008-12-25
MY161457A (en)	2017-04-14
JP5075120B2 (ja)	2012-11-14
US20120083585A1 (en)	2012-04-05

Publication	Publication Date	Title
ATE475706T1 (de)	2010-08-15	Abgeschwächter dengue-serotyp-2-stamm
ZA200710714B (en)	2008-11-26	Dengue serotype 1 attenuated strain
ATE469145T1 (de)	2010-06-15	4-ä5-methoxy-6-(2-methyl-6-ä1,2,4ütriazol-1-yl-
DE602007009284D1 (de)	2010-10-28	3-aza-bicycloä3.1.0ühexanderivate
DE502006000770D1 (de)	2008-06-26	Konservierungsmittel
ATE535505T1 (de)	2011-12-15	Landwirtschaftliche zusammensetzung
BRPI0816970A2 (pt)	2015-03-24	1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
DE602007001681D1 (de)	2009-09-03	1,3-dioxan-carboxylsäuren
DK2205562T3 (da)	2011-06-14	1,1,1-trifluor-2-hydroxy-3-phenylpropanderivater
ATE537171T1 (de)	2011-12-15	Aryl-isoxazol-4-yl-imidazoä1,5-aüpyridin-deriva e
DK1741339T3 (da)	2014-05-12	Pesticid sammensætning
EP1976974A4 (de)	2009-12-09	Pneumococcus-serotypen
DK1865813T3 (da)	2012-12-10	Fastgørelsesbøjle
DE502006003938D1 (de)	2009-07-23	Roststab
ATE538121T1 (de)	2012-01-15	1,5,6-substituierte-2-oxo-3-cyano-1,6a- diazatetrahydrofluoranthene als antiinfektionsmittel
FI20055434A0 (fi)	2005-08-12	Reftraktometri
FI20055407A0 (fi)	2005-07-12	Kalanteri
ATE412728T1 (de)	2008-11-15	Bleichmittel
EP1940415A4 (de)	2010-03-17	19,23,24,25,26,27-hexanor-1alpha-hydroxyvitamin d3
DE502005007729D1 (de)	2009-08-27	Kalander
UA13036S (uk)	2006-11-15	Барна стійка
ITMI20050295U1 (it)	2007-02-12	Tovagliette sottopiatto migliorate
DE502006001048D1 (de)	2008-08-21	Kombileiste
ITFR20050004U1 (it)	2006-08-12	Traliccio "conte" muniti di due piattinecon tondino distanziatore
ITDP20060026A1 (it)	2008-02-29	Multisnodo 1

Legal Events

Date	Code	Title	Description
2011-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties