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ATE465990T1 - Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen - Google Patents

Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen

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Publication number
ATE465990T1
ATE465990T1 AT04704251T AT04704251T ATE465990T1 AT E465990 T1 ATE465990 T1 AT E465990T1 AT 04704251 T AT04704251 T AT 04704251T AT 04704251 T AT04704251 T AT 04704251T AT E465990 T1 ATE465990 T1 AT E465990T1
Authority
AT
Austria
Prior art keywords
arylalkylcarbamat
derivatives
production
therapeutic applications
therapeutic
Prior art date
Application number
AT04704251T
Other languages
English (en)
Inventor
Ahmed Abouabdellah
Garcia Antonio Almario
Christian Hoornaert
Antoine Ravet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of ATE465990T1 publication Critical patent/ATE465990T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
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    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
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    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
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    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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AT04704251T 2003-01-23 2004-01-22 Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen ATE465990T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0300704A FR2850377B1 (fr) 2003-01-23 2003-01-23 Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
PCT/FR2004/000139 WO2004067498A2 (fr) 2003-01-23 2004-01-22 Derives d’ arylalkylcarbamates, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ATE465990T1 true ATE465990T1 (de) 2010-05-15

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AT04704251T ATE465990T1 (de) 2003-01-23 2004-01-22 Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen

Country Status (34)

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US (1) US7632850B2 (de)
EP (1) EP1590321B1 (de)
JP (1) JP4617292B2 (de)
KR (1) KR20050104352A (de)
CN (2) CN101058564B (de)
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EP3988540A1 (de) 2014-04-07 2022-04-27 The Regents of the University of California Inhibitoren des enzyms der fettsäureamidhydrolase (faah) mit verbesserter oraler bioverfügbarkeit und deren verwendung als arzneimittel
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CA2511941A1 (en) 2004-08-12
ZA200505351B (en) 2006-09-27
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CN101058564B (zh) 2010-05-26
NZ541148A (en) 2009-01-31
NO20053593D0 (no) 2005-07-22
CN1741990A (zh) 2006-03-01
FR2850377B1 (fr) 2009-02-20
DE602004026826D1 (de) 2010-06-10
HRP20050631A2 (en) 2005-08-31
MXPA05007848A (es) 2005-10-18
BRPI0406901A (pt) 2005-12-13
US7632850B2 (en) 2009-12-15
IL169444A (en) 2011-06-30
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CY1110216T1 (el) 2015-01-14
DK1590321T3 (da) 2010-08-09
AU2004207657B2 (en) 2010-09-16
US20060014830A1 (en) 2006-01-19
MEP21308A (en) 2010-06-10
TNSN05172A1 (fr) 2007-05-14
EA008801B1 (ru) 2007-08-31
TWI330628B (en) 2010-09-21
CN101058564A (zh) 2007-10-24
JP2006517218A (ja) 2006-07-20
FR2850377A1 (fr) 2004-07-30
WO2004067498A3 (fr) 2004-11-04
AR042746A1 (es) 2005-06-29
EP1590321A2 (de) 2005-11-02
SI1590321T1 (sl) 2010-08-31
IL169444A0 (en) 2007-07-04
ES2344454T3 (es) 2010-08-27
PT1590321E (pt) 2010-07-06
EP1590321B1 (de) 2010-04-28
AU2004207657A1 (en) 2004-08-12
UA86013C2 (ru) 2009-03-25
NO20053593L (no) 2005-10-21
WO2004067498A2 (fr) 2004-08-12
CN100506788C (zh) 2009-07-01
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