ATE465753T1 - Zusammensetzungen und verfahren zurbehandlung von krankheiten, die durch das humane papillomavirus vermitteltwerden - Google Patents
Zusammensetzungen und verfahren zurbehandlung von krankheiten, die durch das humane papillomavirus vermitteltwerdenInfo
- Publication number
- ATE465753T1 ATE465753T1 AT03776419T AT03776419T ATE465753T1 AT E465753 T1 ATE465753 T1 AT E465753T1 AT 03776419 T AT03776419 T AT 03776419T AT 03776419 T AT03776419 T AT 03776419T AT E465753 T1 ATE465753 T1 AT E465753T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- diseases caused
- treating diseases
- papilloma virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/892—Reproductive system [uterus, ovaries, cervix, testes]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42006802P | 2002-10-21 | 2002-10-21 | |
US47148103P | 2003-05-15 | 2003-05-15 | |
PCT/US2003/032705 WO2004037175A2 (en) | 2002-10-21 | 2003-10-16 | Compositions and methods for treating human papillomavirus-mediated disease |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE465753T1 true ATE465753T1 (de) | 2010-05-15 |
Family
ID=32179780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03776419T ATE465753T1 (de) | 2002-10-21 | 2003-10-16 | Zusammensetzungen und verfahren zurbehandlung von krankheiten, die durch das humane papillomavirus vermitteltwerden |
Country Status (8)
Country | Link |
---|---|
US (2) | US20060247190A1 (de) |
EP (1) | EP1556513B1 (de) |
JP (2) | JP2006503914A (de) |
AT (1) | ATE465753T1 (de) |
AU (2) | AU2003284239B2 (de) |
CA (1) | CA2502696A1 (de) |
DE (1) | DE60332377D1 (de) |
WO (1) | WO2004037175A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101180885B1 (ko) | 2006-04-19 | 2012-09-10 | 포항공과대학교 산학협력단 | 자궁경부암의 예방 및 치료를 위한 사람 파필로마바이러스폴리펩타이드와 면역 증강제를 포함하는 조성물 |
CN101426810A (zh) * | 2006-04-21 | 2009-05-06 | 特朗斯吉恩股份有限公司 | 基于hpv-18的乳头瘤病毒疫苗 |
JP2009534332A (ja) * | 2006-04-21 | 2009-09-24 | トランジェーヌ、ソシエテ、アノニム | パピローマウイルスワクチン |
CA3057039C (en) | 2006-07-28 | 2023-02-28 | The Trustees Of The University Of Pennsylvania | Hiv consensus envelope sequences and methods for using same |
US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
CA2721366C (en) | 2008-04-17 | 2017-06-06 | Elizabeth Ann Vasievich | Stimulation of an immune response by enantiomers of cationic lipids |
CA2731444A1 (en) * | 2008-09-02 | 2010-03-11 | Antigen Express, Inc. | Human papillomavirus / li-key hybrids and methods of use |
EP2601968A1 (de) | 2011-12-06 | 2013-06-12 | Deutsches Krebsforschungszentrum | HPV-abgeleitete Polynucleinsäure zur Therapie |
ES2777935T3 (es) | 2012-06-15 | 2020-08-06 | Pds Biotechnology Corp | Composiciones de vacunas de lípidos catiónicos y procedimiento de uso |
CA2885741C (en) | 2012-09-21 | 2023-10-17 | Frank Bedu-Addo | Vaccine comprising r-dotap |
WO2017083820A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
BE1024774B1 (fr) * | 2016-09-29 | 2018-07-02 | Glaxosmithkline Biologicals Sa | Compositions et procedes de traitement |
JP2020515542A (ja) * | 2017-03-23 | 2020-05-28 | ザ ジェネラル ホスピタル コーポレイション | Cxcr4/cxcr7の遮断およびヒトパピローマウイルス関連疾患の治療 |
US20230241207A1 (en) * | 2017-04-03 | 2023-08-03 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
WO2021026335A1 (en) * | 2019-08-08 | 2021-02-11 | The Trustees Of Indiana University | Methods for identifying and treating urinary tract infections |
CN112957461B (zh) * | 2021-02-02 | 2023-01-10 | 南开大学 | 一种形貌可控自佐剂宫颈癌多肽疫苗的制备及性能表征方法 |
WO2024180232A1 (en) * | 2023-03-02 | 2024-09-06 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Therapeutic hpv vaccines based on validated target epitopes |
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KR930007580B1 (ko) * | 1986-03-21 | 1993-08-13 | 엥스띠뛰 빠스뙤르 | 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법 |
US4741872A (en) * | 1986-05-16 | 1988-05-03 | The University Of Kentucky Research Foundation | Preparation of biodegradable microspheres useful as carriers for macromolecules |
US4777239A (en) * | 1986-07-10 | 1988-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic peptides of human papilloma virus |
US6007806A (en) * | 1986-08-13 | 1999-12-28 | Transgene S.A. | Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventive or curative treatment of the corresponding tumor |
US5075109A (en) * | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
DE3907721A1 (de) * | 1989-03-10 | 1990-09-20 | Behringwerke Ag | Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16 |
US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5753233A (en) * | 1990-05-10 | 1998-05-19 | Behring Diagnostics Gmbh | Seroreactive epitopes on proteins of human papilloma-virus (HPV) 18 |
US5932412A (en) * | 1990-05-11 | 1999-08-03 | Euro-Diagnostica Ab | Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes |
US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
US6183745B1 (en) * | 1990-12-12 | 2001-02-06 | The University Of Queensland | Subunit papilloma virus vaccine and peptides for use therein |
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GB9105383D0 (en) * | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
US5543294A (en) | 1991-07-19 | 1996-08-06 | The Trustees Of Columbia University In The City Of New York | Polymerase chain reaction/restriction fragment length polymorphism method for the detection and typing of myobacteria |
US5709860A (en) * | 1991-07-25 | 1998-01-20 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
US6037135A (en) * | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
US5656297A (en) * | 1992-03-12 | 1997-08-12 | Alkermes Controlled Therapeutics, Incorporated | Modulated release from biocompatible polymers |
EP0630234B1 (de) * | 1992-03-12 | 1997-06-11 | Alkermes Controlled Therapeutics, Inc. | Acth enthaltende mikrokugeln mit gesteuerter abgabe |
CA2142007C (en) * | 1992-08-11 | 2007-10-30 | Robert Glen Urban | Immunomodulatory peptides |
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US5633234A (en) * | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
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US5993434A (en) | 1993-04-01 | 1999-11-30 | Genetronics, Inc. | Method of treatment using electroporation mediated delivery of drugs and genes |
US5679647A (en) * | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
US5679509A (en) * | 1993-09-28 | 1997-10-21 | University Of New Mexico | Methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer |
US5643605A (en) * | 1993-10-25 | 1997-07-01 | Genentech, Inc. | Methods and compositions for microencapsulation of adjuvants |
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US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
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EP0934083B1 (de) * | 1996-10-23 | 2009-04-29 | The Trustees Of The University Of Pennsylvania | Verbesserte impfstoffe |
US20020103145A1 (en) * | 1999-05-19 | 2002-08-01 | Adrian Bot | Immunization of infants |
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US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
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US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
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JP2001526045A (ja) | 1997-12-12 | 2001-12-18 | ダイジーン・コーポレーション | ヒトパピローマウイルス関連疾患の評価 |
GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
EP1078092B1 (de) * | 1998-05-13 | 2011-08-03 | Epimmune Inc. | Expressionsvektoren zur stimulierung einer immunantwort und verfahren zu deren verwendung |
US6406719B1 (en) | 1998-05-13 | 2002-06-18 | Microbiological Research Authority | Encapsulation of bioactive agents |
AU771262B2 (en) | 1998-08-12 | 2004-03-18 | Eisai Inc. | Profiling and cataloging expressed protein tags |
EP1108035B1 (de) * | 1998-09-04 | 2007-08-08 | Sanofi Pasteur Limited | Behandlung von gebärmutterhalskrebs |
CA2276066A1 (en) | 1999-03-11 | 2000-09-11 | Zycos Inc. | Microparticles for delivery of nucleic acid |
US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
EP1214097B3 (de) * | 1999-09-16 | 2011-07-20 | Eisai Inc. | Für polyepitop-polypeptide kodierende nukleinsäuren |
WO2001027291A1 (en) * | 1999-10-12 | 2001-04-19 | Institut Pasteur | Design of a polyepitopic construct for the induction of hla-a2.1 restricted hiv 1 specific ctl responses using hhd mice |
ATE319810T1 (de) | 1999-11-19 | 2006-03-15 | Zycos Inc | Durchflussverfahren zur herstellung von mikropartikeln |
WO2001097795A2 (en) | 2000-06-22 | 2001-12-27 | 3M Innovative Properties Company | Systems and methods for treating a mucosal surface |
MXPA02012858A (es) * | 2000-06-26 | 2004-04-20 | Stressgen Biotechnologies Corp | Tratamiento de virus de papiloma humano. |
GB0017990D0 (en) * | 2000-07-21 | 2000-09-13 | Glaxo Group Ltd | Papilloma virus sequences |
-
2003
- 2003-10-16 JP JP2005501623A patent/JP2006503914A/ja active Pending
- 2003-10-16 US US10/532,168 patent/US20060247190A1/en not_active Abandoned
- 2003-10-16 AU AU2003284239A patent/AU2003284239B2/en not_active Ceased
- 2003-10-16 CA CA002502696A patent/CA2502696A1/en not_active Abandoned
- 2003-10-16 DE DE60332377T patent/DE60332377D1/de not_active Expired - Lifetime
- 2003-10-16 EP EP03776419A patent/EP1556513B1/de not_active Expired - Lifetime
- 2003-10-16 WO PCT/US2003/032705 patent/WO2004037175A2/en active Application Filing
- 2003-10-16 AT AT03776419T patent/ATE465753T1/de not_active IP Right Cessation
-
2008
- 2008-11-21 AU AU2008249148A patent/AU2008249148A1/en not_active Abandoned
-
2010
- 2010-06-07 US US12/795,483 patent/US20110158952A1/en not_active Abandoned
- 2010-12-10 JP JP2010275323A patent/JP2011121946A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60332377D1 (de) | 2010-06-10 |
US20060247190A1 (en) | 2006-11-02 |
EP1556513A2 (de) | 2005-07-27 |
AU2003284239A1 (en) | 2004-05-13 |
AU2008249148A1 (en) | 2008-12-11 |
AU2003284239B2 (en) | 2008-08-21 |
WO2004037175A2 (en) | 2004-05-06 |
CA2502696A1 (en) | 2004-05-06 |
EP1556513B1 (de) | 2010-04-28 |
EP1556513A4 (de) | 2007-03-14 |
US20110158952A1 (en) | 2011-06-30 |
JP2011121946A (ja) | 2011-06-23 |
JP2006503914A (ja) | 2006-02-02 |
WO2004037175A3 (en) | 2004-07-29 |
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