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ATE459004T1 - Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung - Google Patents

Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung

Info

Publication number
ATE459004T1
ATE459004T1 AT05010407T AT05010407T ATE459004T1 AT E459004 T1 ATE459004 T1 AT E459004T1 AT 05010407 T AT05010407 T AT 05010407T AT 05010407 T AT05010407 T AT 05010407T AT E459004 T1 ATE459004 T1 AT E459004T1
Authority
AT
Austria
Prior art keywords
receptor
protein
fprl2
ligand
application
Prior art date
Application number
AT05010407T
Other languages
English (en)
Inventor
Isabelle Migeotte
Marc Parmentier
David Communi
Maryse Brait
Original Assignee
Euroscreen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroscreen Sa filed Critical Euroscreen Sa
Application granted granted Critical
Publication of ATE459004T1 publication Critical patent/ATE459004T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05010407T 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung ATE459004T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04447122 2004-05-14
EP04447231 2004-10-18

Publications (1)

Publication Number Publication Date
ATE459004T1 true ATE459004T1 (de) 2010-03-15

Family

ID=34982585

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05010407T ATE459004T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung
AT08159325T ATE496304T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen-2 (fprl2) g protein gekoppelten rezeptor

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT08159325T ATE496304T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen-2 (fprl2) g protein gekoppelten rezeptor

Country Status (7)

Country Link
US (3) US7582416B2 (de)
EP (2) EP2020604B1 (de)
JP (2) JP4694887B2 (de)
AT (2) ATE459004T1 (de)
CA (2) CA2810292C (de)
DE (2) DE602005019495D1 (de)
DK (2) DK2020604T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1447600A (en) * 1998-10-22 2000-05-08 Thomas J. Gardella Bioactive peptides and peptide derivatives of parathyroid hormone (pth) and parathyroid hormone-related peptide (pthrp)
WO2001023521A2 (en) * 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
AU2002339843B2 (en) * 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
EP2201960A1 (de) * 2003-03-19 2010-06-30 The General Hospital Corporation Konformationseingeschränkte Parathormone mit Alpha-Helix-Stabilisatoren
JP4871128B2 (ja) 2003-07-17 2012-02-08 ザ ジェネラル ホスピタル コーポレイション 高次構造的に制約された副甲状腺ホルモン(pth)アナログ
CA2810292C (en) * 2004-05-14 2015-09-29 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof
WO2008019062A2 (en) * 2006-08-04 2008-02-14 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
US20090004755A1 (en) * 2007-03-23 2009-01-01 Biosite, Incorporated Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
US8221995B2 (en) * 2007-03-23 2012-07-17 Seok-Won Lee Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
PE20090321A1 (es) 2007-06-04 2009-04-20 Genentech Inc Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
US20100297621A1 (en) * 2007-06-20 2010-11-25 University Of Utah Research Foundation Use of pre-mrna splicing in platelet cells for the diagnosis of disease
CA3017668C (en) * 2007-08-01 2021-11-09 The General Hospital Corporation Screening methods using g-protein coupled receptors and related compositions
BRPI0922820A2 (pt) 2008-12-04 2015-12-22 Sanofi Sa métodos e usos envolvendo a proteína de ligação ao heme 1
CN102414168B (zh) 2009-05-18 2014-05-21 埃科特莱茵药品有限公司 用作为alx受体和/或fprl2激动剂的桥联螺[2.4]庚烷衍生物
WO2011073918A2 (en) 2009-12-16 2011-06-23 Actelion Pharmaceuticals Ltd Peptides as modulators of fprl1 and/or fprl2
KR101900078B1 (ko) 2010-05-13 2018-09-18 더 제너럴 하스피탈 코포레이션 부갑상선 호르몬 아날로그 및 그의 용도
WO2016207124A1 (en) * 2015-06-25 2016-12-29 F. Hoffmann-La Roche Ag Cell based assay for determining antibody or ligand binding and function

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919649A (en) 1988-11-18 1999-07-06 The General Hospital Corporation Camp-responsive transcriptional enhancer binding protein
CA2119930C (en) 1991-09-23 2002-10-01 Hendricus R. J. M. Hoogenboom Production of chimeric antibodies - a combinatorial approach
CA2115811A1 (en) 1993-02-17 1994-08-18 Claus Krebber A method for in vivo selection of ligand-binding proteins
PT859841E (pt) 1995-08-18 2002-11-29 Morphosys Ag Bibliotecas de proteinas/ (poli) peptidos
US7119190B2 (en) * 1997-04-14 2006-10-10 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human G protein-coupled receptors
EP1145002B2 (de) 1998-07-06 2008-12-10 PerkinElmer Cellular Sciences Belgium BVBA Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors
AU7494200A (en) * 1999-09-15 2001-04-17 Incyte Genomics, Inc. Proteins associated with cell differentiation
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
JP4184875B2 (ja) * 2002-06-14 2008-11-19 武田薬品工業株式会社 新規スクリーニング方法
CA2810292C (en) * 2004-05-14 2015-09-29 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof

Also Published As

Publication number Publication date
JP2006025787A (ja) 2006-02-02
EP2020604B1 (de) 2011-01-19
DE602005026072D1 (de) 2011-03-03
DK1607745T3 (da) 2010-06-14
US7582416B2 (en) 2009-09-01
CA2504920C (en) 2014-04-01
CA2810292A1 (en) 2005-11-14
US7842795B2 (en) 2010-11-30
US20090053739A1 (en) 2009-02-26
ATE496304T1 (de) 2011-02-15
CA2504920A1 (en) 2005-11-14
EP1607745B1 (de) 2010-02-24
US20060078559A1 (en) 2006-04-13
EP2020604A1 (de) 2009-02-04
JP5314061B2 (ja) 2013-10-16
DK2020604T3 (da) 2011-05-16
JP2011078437A (ja) 2011-04-21
JP4694887B2 (ja) 2011-06-08
EP1607745A3 (de) 2006-07-26
US20100009406A1 (en) 2010-01-14
EP1607745A2 (de) 2005-12-21
CA2810292C (en) 2015-09-29
US7659251B2 (en) 2010-02-09
DE602005019495D1 (de) 2010-04-08

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