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ATE458053T1 - Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren - Google Patents

Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren

Info

Publication number
ATE458053T1
ATE458053T1 AT07123073T AT07123073T ATE458053T1 AT E458053 T1 ATE458053 T1 AT E458053T1 AT 07123073 T AT07123073 T AT 07123073T AT 07123073 T AT07123073 T AT 07123073T AT E458053 T1 ATE458053 T1 AT E458053T1
Authority
AT
Austria
Prior art keywords
methods
receptor proteins
receptors
human toll
human
Prior art date
Application number
AT07123073T
Other languages
English (en)
Inventor
Gerard T Hardiman
Fernando J Bazan
Fernando L Rock
Robert A Kastelein
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27366459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE458053(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE458053T1 publication Critical patent/ATE458053T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT07123073T 1997-05-07 1998-05-07 Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren ATE458053T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4429397P 1997-05-07 1997-05-07
US7221298P 1998-01-22 1998-01-22
US7694798P 1998-03-05 1998-03-05

Publications (1)

Publication Number Publication Date
ATE458053T1 true ATE458053T1 (de) 2010-03-15

Family

ID=27366459

Family Applications (3)

Application Number Title Priority Date Filing Date
AT07123073T ATE458053T1 (de) 1997-05-07 1998-05-07 Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren
AT98918934T ATE348157T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähnliche rezeptorproteine, zugehörige reagenzien und verfahren
AT06025414T ATE443139T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT98918934T ATE348157T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähnliche rezeptorproteine, zugehörige reagenzien und verfahren
AT06025414T ATE443139T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren

Country Status (19)

Country Link
EP (4) EP1988166A1 (de)
JP (4) JP2002514083A (de)
KR (1) KR100388860B1 (de)
CN (4) CN1935840A (de)
AT (3) ATE458053T1 (de)
AU (1) AU740333B2 (de)
CA (1) CA2289912C (de)
CY (1) CY1109645T1 (de)
DE (3) DE69841514D1 (de)
DK (2) DK0980429T3 (de)
ES (3) ES2331622T3 (de)
ID (1) ID28299A (de)
IL (1) IL132614A0 (de)
NO (1) NO995458D0 (de)
NZ (1) NZ338073A (de)
PL (1) PL336635A1 (de)
PT (1) PT1798288E (de)
SK (1) SK146599A3 (de)
WO (1) WO1998050547A2 (de)

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US20030032090A1 (en) 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
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US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
EP1283849A2 (de) * 2000-05-25 2003-02-19 Schering Corporation Menschlische-rezeptor proteine; verwandte reagenzien und methoden
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
KR20120053525A (ko) 2000-06-16 2012-05-25 캠브리지 안티바디 테크놀로지 리미티드 면역특이적으로 ＢＬｙＳ에 결합하는 항체
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EP2184291A1 (de) * 2000-08-18 2010-05-12 Dyax Corp. Bindepolypeptide für B-Lymphozyten-Stimulatorprotein (BLyS)
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US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
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EP1697389A4 (de) 2003-10-24 2008-12-24 Eisai R&D Man Co Ltd Verbindungen und verfahren zur behandlung von mit dem toll-like receptor 2 in zusammenhang stehenden krankheiten und leiden
AU2004293078B2 (en) 2003-11-25 2012-01-19 3M Innovative Properties Company Substituted imidazo ring systems and methods
JP2008022701A (ja) * 2004-09-24 2008-02-07 Japan Science & Technology Agency 可溶型Ｔｏｌｌ様受容体４タンパク質
CA2587676A1 (en) 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
TWI487535B (zh) 2004-11-30 2015-06-11 Centocor Inc 類鐸受體３（ｔｏｌｌ ｌｉｋｅ ｒｅｃｅｐｔｏｒ３）拮抗劑，方法及用途
WO2006084251A2 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
US7700728B2 (en) 2005-03-24 2010-04-20 Schering Corporation Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors
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US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
ES2435775T3 (es) 2005-10-27 2013-12-23 Janssen Biotech, Inc. Moduladores de receptor tipo Toll 3, procedimientos y usos
TW200745158A (en) 2006-03-07 2007-12-16 Vaxinnate Corp Compositions that include hemagglutinin, methods of making and methods of use thereof
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CN101134046B (zh) * 2006-09-01 2011-10-05 中国医学科学院药物研究所 Tlr4和tlr9激动剂复方在抑制肿瘤转移中的应用
JP2010527633A (ja) * 2007-05-25 2010-08-19 セントコア・オーソ・バイオテツク・インコーポレーテツド Ｔｏｌｌ様受容体３モジュレーター及びその使用
CA2722589A1 (en) 2008-04-25 2009-10-29 Innate Pharma Improved tlr3 agonist compositions
EP2116602A1 (de) 2008-05-07 2009-11-11 Institut Gustave Roussy Kombinationsprodukte zur Behandlung von Krebs
EP2334703B1 (de) 2008-09-17 2015-07-08 Innate Pharma Zusammensetzungen und verfahren zum nachweis von tlr3
EP2328911A4 (de) 2008-09-22 2012-03-14 Cedars Sinai Medical Center Kurzes menschliches md-2 als negativer regulator der toll-like-rezeptor-4-signalisierung
US9512196B2 (en) 2008-09-22 2016-12-06 Cedars-Sinai Medical Center Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling
WO2011004028A2 (en) 2009-07-10 2011-01-13 Innate Pharma Tlr3 binding agents
WO2011021524A1 (ja) * 2009-08-19 2011-02-24 国立大学法人名古屋大学 乳酸菌の付着性を誘導するペプチド及びその用途
EP2596009B1 (de) 2010-07-19 2017-08-23 Yeda Research and Development Co. Ltd. Peptide, basierend auf der transmembrandomäne eines "toll-like" rezeptors (tlr) für die behandlung einer tlr-vermittelten krankheit
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US20140065154A1 (en) 2011-01-12 2014-03-06 Innate Pharma Tlr3 binding agents
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EP2766384B1 (de) * 2011-10-10 2016-11-23 Yeda Research and Development Co. Ltd. Agonistenpeptide aus dem rezeptor des typs toll-4 (tlr-4) zur modulierung der immunreaktions vom tlr-4 verursacht
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Also Published As

Publication number Publication date
EP1925666B1 (de) 2010-02-17
JP2006052232A (ja) 2006-02-23
DE69841514D1 (de) 2010-04-01
DE69836630T2 (de) 2007-10-11
WO1998050547A3 (en) 1999-03-11
ES2340210T3 (es) 2010-05-31
EP1925666A1 (de) 2008-05-28
CN1935840A (zh) 2007-03-28
DE69841170D1 (de) 2009-10-29
IL132614A0 (en) 2001-03-19
DE69836630D1 (de) 2007-01-25
CN1800214A (zh) 2006-07-12
CA2289912A1 (en) 1998-11-12
NO995458L (no) 1999-11-08
CA2289912C (en) 2011-07-26
NZ338073A (en) 2001-09-28
EP1798288A3 (de) 2007-09-12
CY1109645T1 (el) 2012-05-23
CN1263555A (zh) 2000-08-16
PT1798288E (pt) 2009-12-23
EP1988166A1 (de) 2008-11-05
CN101486759A (zh) 2009-07-22
KR20010012323A (ko) 2001-02-15
NO995458D0 (no) 1999-11-08
SK146599A3 (en) 2000-07-11
KR100388860B1 (ko) 2003-06-25
ES2279572T3 (es) 2007-08-16
ES2331622T3 (es) 2010-01-11
EP0980429A2 (de) 2000-02-23
EP0980429B1 (de) 2006-12-13
EP1798288A2 (de) 2007-06-20
JP2005120106A (ja) 2005-05-12
DK0980429T3 (da) 2007-04-10
AU740333B2 (en) 2001-11-01
PL336635A1 (en) 2000-07-03
CN1225555C (zh) 2005-11-02
ATE443139T1 (de) 2009-10-15
EP1798288B1 (de) 2009-09-16
DK1798288T3 (da) 2010-01-04
ATE348157T1 (de) 2007-01-15
WO1998050547A2 (en) 1998-11-12
JP2009089713A (ja) 2009-04-30
JP2002514083A (ja) 2002-05-14
AU7175498A (en) 1998-11-27
HK1022175A1 (en) 2000-07-28
HK1112018A1 (en) 2008-08-22
HK1102720A1 (en) 2007-12-07
ID28299A (id) 2001-05-10

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