ATE451384T1 - Verfahren zur herstellung von peptiden - Google Patents
Verfahren zur herstellung von peptidenInfo
- Publication number
- ATE451384T1 ATE451384T1 AT04817655T AT04817655T ATE451384T1 AT E451384 T1 ATE451384 T1 AT E451384T1 AT 04817655 T AT04817655 T AT 04817655T AT 04817655 T AT04817655 T AT 04817655T AT E451384 T1 ATE451384 T1 AT E451384T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- peptide
- sup
- silver
- amide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 9
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 3
- 150000001408 amides Chemical class 0.000 abstract 3
- 125000006239 protecting group Chemical group 0.000 abstract 3
- 229910052709 silver Inorganic materials 0.000 abstract 3
- 239000004332 silver Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- QUOGESRFPZDMMT-YFKPBYRVSA-N L-homoarginine Chemical group OC(=O)[C@@H](N)CCCCNC(N)=N QUOGESRFPZDMMT-YFKPBYRVSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011097 chromatography purification Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- -1 thioalkyl carboxylic acid Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 150000003573 thiols Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN648MU2004 | 2004-06-14 | ||
| PCT/IN2004/000315 WO2005121164A1 (en) | 2004-06-14 | 2004-10-10 | Process for the preparation of peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE451384T1 true ATE451384T1 (de) | 2009-12-15 |
Family
ID=34961110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04817655T ATE451384T1 (de) | 2004-06-14 | 2004-10-10 | Verfahren zur herstellung von peptiden |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080182781A1 (de) |
| EP (1) | EP1756141B1 (de) |
| JP (1) | JP2008503597A (de) |
| CN (1) | CN1968961A (de) |
| AT (1) | ATE451384T1 (de) |
| AU (1) | AU2004320599A1 (de) |
| CA (1) | CA2560007A1 (de) |
| DE (1) | DE602004024593D1 (de) |
| EA (1) | EA200601714A1 (de) |
| WO (1) | WO2005121164A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005298991B2 (en) | 2004-10-19 | 2011-03-03 | Polypeptide Laboratories Holding (Ppl) Ab | On-resin peptide cyclization |
| CN100355773C (zh) * | 2006-01-19 | 2007-12-19 | 九江石化波涛生化科技有限公司 | 高分子量多肽聚合物的合成方法 |
| EP2062909A1 (de) * | 2007-11-21 | 2009-05-27 | SOLVAY (Société Anonyme) | Herstellung von Peptiden und Reinigungsverfahren |
| US9051349B2 (en) | 2007-11-21 | 2015-06-09 | Alba Therapeutics Corporation | Larazotide acetate compositions |
| GB0814519D0 (en) | 2008-08-08 | 2008-09-17 | Imp Innovations Ltd | Process |
| CN102573459A (zh) * | 2009-08-04 | 2012-07-11 | 弗·哈夫曼-拉罗切有限公司 | 粘度降低的浓缩多肽制剂 |
| EP3088417A1 (de) * | 2015-04-28 | 2016-11-02 | Vallaurix Pte. Ltd. | Pharmazeutische zusammensetzung |
| CN107686512A (zh) * | 2016-08-05 | 2018-02-13 | 首都医科大学 | 甲基咔啉‑3‑甲酰yigs肽,其合成,抗血栓作用和应用 |
| US11560402B2 (en) * | 2018-04-10 | 2023-01-24 | Sanofi-Aventis Deutschland Gmbh | Method for cleavage of solid phase-bound peptides from the solid phase |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| WO2003093302A2 (en) * | 2002-05-03 | 2003-11-13 | Avecia Limited | Process for the synthesis of peptides amides by side-chain attachement to a solid phase |
| PT1511761E (pt) * | 2003-04-07 | 2006-11-30 | Novetide Ltd | Processo para produção peptídeos cíclicos |
-
2004
- 2004-10-10 CN CNA2004800431098A patent/CN1968961A/zh active Pending
- 2004-10-10 EA EA200601714A patent/EA200601714A1/ru unknown
- 2004-10-10 AU AU2004320599A patent/AU2004320599A1/en not_active Abandoned
- 2004-10-10 AT AT04817655T patent/ATE451384T1/de not_active IP Right Cessation
- 2004-10-10 EP EP04817655A patent/EP1756141B1/de not_active Expired - Lifetime
- 2004-10-10 US US10/592,118 patent/US20080182781A1/en not_active Abandoned
- 2004-10-10 DE DE602004024593T patent/DE602004024593D1/de not_active Expired - Lifetime
- 2004-10-10 JP JP2007526703A patent/JP2008503597A/ja not_active Withdrawn
- 2004-10-10 CA CA002560007A patent/CA2560007A1/en not_active Abandoned
- 2004-10-10 WO PCT/IN2004/000315 patent/WO2005121164A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005121164A1 (en) | 2005-12-22 |
| US20080182781A1 (en) | 2008-07-31 |
| EA200601714A1 (ru) | 2007-06-29 |
| AU2004320599A1 (en) | 2005-12-22 |
| EP1756141A1 (de) | 2007-02-28 |
| CA2560007A1 (en) | 2005-12-22 |
| CN1968961A (zh) | 2007-05-23 |
| EP1756141B1 (de) | 2009-12-09 |
| JP2008503597A (ja) | 2008-02-07 |
| WO2005121164A9 (en) | 2006-03-02 |
| DE602004024593D1 (de) | 2010-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |