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ATE446290T1 - Substituierte n-acyl-homoserinlactone - Google Patents

Substituierte n-acyl-homoserinlactone

Info

Publication number
ATE446290T1
ATE446290T1 AT07733705T AT07733705T ATE446290T1 AT E446290 T1 ATE446290 T1 AT E446290T1 AT 07733705 T AT07733705 T AT 07733705T AT 07733705 T AT07733705 T AT 07733705T AT E446290 T1 ATE446290 T1 AT E446290T1
Authority
AT
Austria
Prior art keywords
acyl homoserine
substituted
homoserine lactones
lactones
acyl
Prior art date
Application number
AT07733705T
Other languages
English (en)
Inventor
David Idris Pritchard
Siri Ram Chhabra
Original Assignee
Secr Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secr Defence filed Critical Secr Defence
Application granted granted Critical
Publication of ATE446290T1 publication Critical patent/ATE446290T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT07733705T 2006-05-22 2007-05-22 Substituierte n-acyl-homoserinlactone ATE446290T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610042.4A GB0610042D0 (en) 2006-05-22 2006-05-22 Substituted n-acyl homoserine lactones
PCT/GB2007/050284 WO2007135466A2 (en) 2006-05-22 2007-05-22 Substituted n-acyl homoserine lactones

Publications (1)

Publication Number Publication Date
ATE446290T1 true ATE446290T1 (de) 2009-11-15

Family

ID=36660536

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07733705T ATE446290T1 (de) 2006-05-22 2007-05-22 Substituierte n-acyl-homoserinlactone

Country Status (10)

Country Link
US (1) US8049020B2 (de)
EP (1) EP2044046B1 (de)
JP (1) JP2009537625A (de)
CN (1) CN101506186A (de)
AT (1) ATE446290T1 (de)
AU (1) AU2007252999A1 (de)
DE (1) DE602007002920D1 (de)
ES (1) ES2334286T3 (de)
GB (2) GB0610042D0 (de)
WO (1) WO2007135466A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102757437B (zh) * 2012-06-12 2014-10-15 中国科学院化学研究所 酞菁纳米棒阵列薄膜及其制备方法与应用
CN103980233B (zh) * 2013-02-08 2017-07-04 中国人民解放军军事医学科学院毒物药物研究所 一种高丝氨酸内酯类衍生物、其制备方法和用途
KR101819874B1 (ko) 2013-03-19 2018-01-17 더 스크립스 리서치 인스티튜트 암 세포를 선택적으로 죽이는 trail 강화제
CN104496737B (zh) * 2014-12-13 2017-12-22 西安近代化学研究所 一种合成α‑胺甲酰基氟乙酸酯化合物的方法
CN104529802A (zh) * 2014-12-13 2015-04-22 西安近代化学研究所 一种合成n,n′-双取代氟代丙二酰胺化合物的方法
WO2017058757A1 (en) 2015-10-01 2017-04-06 The University Of Toledo Use of acyl-homoserine lactone derivatives as anti-thrombotic agents
CN110003148B (zh) * 2019-04-29 2023-03-24 安徽安力肽生物科技有限公司 一种高丝氨酸内酯盐酸盐的制备方法
EP4305020A1 (de) 2021-03-09 2024-01-17 Basf Se Malonamide und ihre verwendung als herbizide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2904556A (en) * 1958-08-06 1959-09-15 Dow Chemical Co Phthalides
GB9108307D0 (en) * 1991-04-18 1991-06-05 Univ Nottingham Autoinducer
ES2139079T3 (es) * 1993-07-02 2000-02-01 Univ Nottingham Compuestos inmunosupresores y antialergicos, tales como n-(3-oxohexanoil)-homoserina-lactona.
US6337347B1 (en) * 1998-06-18 2002-01-08 The Research & Development Institute, Inc. Autoinducer compounds
GB0007588D0 (en) 2000-03-30 2000-05-17 Univ Nottingham N-Acyl homoserine lactones

Also Published As

Publication number Publication date
US8049020B2 (en) 2011-11-01
WO2007135466A2 (en) 2007-11-29
GB2452436A (en) 2009-03-04
WO2007135466A3 (en) 2008-01-10
GB0610042D0 (en) 2006-06-28
CN101506186A (zh) 2009-08-12
ES2334286T3 (es) 2010-03-08
EP2044046B1 (de) 2009-10-21
EP2044046A2 (de) 2009-04-08
US20100286261A1 (en) 2010-11-11
DE602007002920D1 (de) 2009-12-03
AU2007252999A1 (en) 2007-11-29
JP2009537625A (ja) 2009-10-29
GB0822066D0 (en) 2009-01-07

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Legal Events

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