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ATE438624T1 - 2-pyridonderivate mit affinität für den cannabinoid-typ-2-rezeptor - Google Patents

2-pyridonderivate mit affinität für den cannabinoid-typ-2-rezeptor

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Publication number
ATE438624T1
ATE438624T1 AT01272859T AT01272859T ATE438624T1 AT E438624 T1 ATE438624 T1 AT E438624T1 AT 01272859 T AT01272859 T AT 01272859T AT 01272859 T AT01272859 T AT 01272859T AT E438624 T1 ATE438624 T1 AT E438624T1
Authority
AT
Austria
Prior art keywords
receptor
affinity
cannabinoid type
alkyl
pyridone derivatives
Prior art date
Application number
AT01272859T
Other languages
English (en)
Inventor
Yukio Tada
Yasuyoshi Iso
Kohji Hanasaki
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE438624T1 publication Critical patent/ATE438624T1/de

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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AT01272859T 2000-12-28 2001-12-26 2-pyridonderivate mit affinität für den cannabinoid-typ-2-rezeptor ATE438624T1 (de)

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EP1357111B1 (de) 2009-08-05
EP1357111A1 (de) 2003-10-29
ES2330719T3 (es) 2009-12-15
BR0116539A (pt) 2003-09-23
US20100081686A1 (en) 2010-04-01
TWI287004B (en) 2007-09-21
JP4137636B2 (ja) 2008-08-20
CY1109514T1 (el) 2014-08-13
EP1357111A4 (de) 2005-10-05
US6977266B2 (en) 2005-12-20
DK1357111T3 (da) 2009-11-02
US20040082619A1 (en) 2004-04-29
US20060052411A1 (en) 2006-03-09
KR100828982B1 (ko) 2008-05-14
PT1357111E (pt) 2009-10-20
CN1492856A (zh) 2004-04-28
CA2433158C (en) 2011-05-10
CA2433158A1 (en) 2002-07-11
US8088924B2 (en) 2012-01-03
KR20060033816A (ko) 2006-04-19
JP2008169217A (ja) 2008-07-24
DE60139506D1 (de) 2009-09-17
US7652141B2 (en) 2010-01-26
CN100575345C (zh) 2009-12-30
KR20030070082A (ko) 2003-08-27
WO2002053543A1 (en) 2002-07-11
JPWO2002053543A1 (ja) 2004-05-13

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