ATE403641T1 - Verfahren zur herstellung von o- desmethylvenlafaxin - Google Patents

Verfahren zur herstellung von o- desmethylvenlafaxin

Info

Publication number: ATE403641T1
Authority: AT; Austria
Prior art keywords: desmethylvenlafaxin; producing
Prior art date: 2001-12-04

Application number

AT02804479T

Other languages

English (en)

Inventor

Beat Weber

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-04

Filing date

2002-12-03

Publication date

2008-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23309595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE403641(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-03 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE403641T1 publication Critical patent/ATE403641T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT02804479T 2001-12-04 2002-12-03 Verfahren zur herstellung von o- desmethylvenlafaxin ATE403641T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US33495301P	2001-12-04	2001-12-04

Publications (1)

Publication Number	Publication Date
ATE403641T1 true ATE403641T1 (de)	2008-08-15

Family

ID=23309595

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02804479T ATE403641T1 (de)	2001-12-04	2002-12-03	Verfahren zur herstellung von o- desmethylvenlafaxin

Country Status (28)

Country	Link
US (4)	US6689912B2 (de)
EP (1)	EP1451143B9 (de)
JP (1)	JP4342312B2 (de)
KR (1)	KR100939650B1 (de)
CN (1)	CN1319934C (de)
AR (1)	AR037622A1 (de)
AT (1)	ATE403641T1 (de)
AU (1)	AU2002357049B2 (de)
BR (1)	BR0214701A (de)
CA (1)	CA2466779C (de)
CO (1)	CO5580816A2 (de)
DE (1)	DE60228118D1 (de)
DK (1)	DK1451143T3 (de)
EC (1)	ECSP045135A (de)
ES (1)	ES2311647T4 (de)
HU (1)	HUP0402269A3 (de)
IL (3)	IL162253A0 (de)
MX (1)	MXPA04005309A (de)
NO (1)	NO20042680L (de)
NZ (1)	NZ533316A (de)
PL (1)	PL369299A1 (de)
PT (1)	PT1451143E (de)
RU (1)	RU2317286C2 (de)
SI (1)	SI1451143T1 (de)
TW (1)	TWI260982B (de)
UA (1)	UA80543C2 (de)
WO (1)	WO2003048104A1 (de)
ZA (1)	ZA200405250B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6342533B1 (en) *	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
JP2003521470A (ja) *	1999-04-06	2003-07-15	セプラコアインコーポレーテッド	ベンラファキシンの誘導体とその調製および使用方法
NZ539791A (en) *	2001-02-12	2006-11-30	Wyeth Corp	Novel succinate salt of o-desmethyl-venlafaxine
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine
CN101257898A (zh) *	2005-07-06	2008-09-03	塞普拉科公司	艾司佐匹克隆与o-去甲基文拉法辛的组合以及治疗绝经期和心境障碍、焦虑症和认知障碍的方法
EP1957470A1 (de) *	2005-12-05	2008-08-20	Wyeth	Verfahren zur selektiven synthese von enantiomeren aus substituierten 1-(2-amino-1-phenyl-ethyl)-cyclohexanolen
EP1973866A1 (de)	2005-12-20	2008-10-01	Synthon B.V.	Verfahren zur herstellung von desvenlafaxin
JP2008546718A (ja) *	2006-04-17	2008-12-25	テバファーマシューティカルインダストリーズリミティド	実質的に純粋なｏ−デスメチルベンラファキシン及びその調製方法。
MX2007016179A (es)	2006-04-17	2008-03-11	Teva Pharma	Formas cristalinas de o-desmetilvenlafaxina.
WO2008035369A2 (en) *	2006-06-30	2008-03-27	Alembic Limited	Novel form of o-desmethyl venlafaxine
CA2656285A1 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
US20080221356A1 (en) *	2006-07-26	2008-09-11	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
CA2656167A1 (en)	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
US20090062572A1 (en) *	2006-07-26	2009-03-05	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
US20090137846A1 (en) *	2006-07-26	2009-05-28	Valerie Niddam-Hildesheim	Processes for the synthesis of O-Desmethylvenlafaxine
WO2008013993A2 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
US20090069601A1 (en) *	2006-07-26	2009-03-12	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
EP2061750A2 (de) *	2006-08-04	2009-05-27	Medichem, S.A.	Verbessertes verfahren zur synthetisierung einer desvenlafaxin-freien base und von salzen oder solvaten daraus
EP2114862A1 (de) *	2007-01-31	2009-11-11	Merck Generics (UK) Limited	Verfahren zur herstellung von o-desmethylvenlafaxin
IN2009DN05509A (de) *	2007-03-14	2010-04-30	Teva Pharma
TR200909798T1 (tr) *	2007-07-12	2010-05-21	Dr. Reddy's Laboratories Ltd.	O-desmetilvenlafaksin.
US8329952B2 (en) *	2007-07-16	2012-12-11	Matrix Laboratories Limited	Process for the preparation of O-desmethylvenlafaxine succinate polymorphic forms
WO2009034434A2 (en) *	2007-09-10	2009-03-19	Cadila Pharmaceuticals Limited	An improved process for the preparation of o-desmethylvenlafaxine
NZ585368A (en)	2007-10-26	2012-07-27	Generics Uk Ltd	Process for preparing o-desmethylvenlafaxine
KR101343027B1 (ko) *	2007-11-26	2013-12-18	테바 파마슈티컬 인더스트리즈 리미티드	Ｏ-데스메틸벤라팍신 푸마레이트의 결정형
WO2009084038A2 (en) *	2007-12-28	2009-07-09	Ind-Swift Laboratories Limited	Improved process for the preparation of 0-desmethyl-venlafaxine
EP2252574A1 (de) *	2008-03-06	2010-11-24	Teva Pharmaceutical Industries Ltd.	Verfahren zur herstellung von dimer-unreinheitsfreiem o-desmethylvenlafaxin
EP2119695A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2119696A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2297087A2 (de) *	2008-06-16	2011-03-23	Teva Pharmaceutical Industries Ltd.	Feste formen von o-desmethylvenlafaxinsalzen
US20100016638A1 (en) *	2008-07-21	2010-01-21	Zdenko Hamersak	Method for preparation of o-desmethylvenlafaxine using polythiolates
AU2009275667A1 (en) *	2008-07-30	2010-02-04	Generics [Uk] Limited	Process for the preparation of O-desmethylvenlafaxine
CZ2008756A3 (cs)	2008-11-27	2010-03-24	Zentiva, A. S.	Zpusob prípravy desvenlafaxinu a jeho solí
CZ200969A3 (cs)	2009-02-06	2010-06-30	Zentiva, K.S.	Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ302145B6 (cs)	2009-07-15	2010-11-10	Zentiva, K. S.	Zpusob prípravy desvenlafaxinu a jeho solí
CA2768377A1 (en)	2009-07-16	2011-01-20	Cipla Limited	Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein
US20110098506A1 (en) *	2009-10-26	2011-04-28	Intas Pharmaceuticals Limited	Method of preparing o-desmethylvenlafaxine
US20110184067A1 (en) *	2010-01-25	2011-07-28	Intas Pharmaceuticals Ltd.	O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
EP2539313A2 (de)	2010-03-29	2013-01-02	Pliva Hrvatska D.O.O.	Kristalline formen von o-desmethylvenlafaxinfumarat
CZ303249B6 (cs)	2010-04-06	2012-06-20	Zentiva, K.S.	Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
EP2394976A1 (de)	2010-06-11	2011-12-14	LEK Pharmaceuticals d.d.	Verfahren zur Demethylierung aromatischer Methylether unter Verwendung von 3-Mercaptopropionsäure
JP6751200B2 (ja)	2017-02-09	2020-09-02	アールエルファインケムプライベートリミテッド	１−［２−（ジメチルアミノ）−１−（４−ヒドロキシフェニル）エチル］−シクロヘキサノール及びその塩の製造方法
CN109232189B (zh) *	2018-09-25	2021-10-08	杭州盛弗泰新材料科技有限公司	一种高纯度1-羟基芘的制备方法
CN109665966A (zh) *	2018-11-01	2019-04-23	山东蒲济医药科技有限公司	一种琥珀酸去甲文拉法辛化合物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2741009A1 (de) *	1976-09-22	1978-03-23	Sandoz Ag	4-styryl-4-indolinol-derivate, ihre verwendung und herstellung
US4535186A (en)	1983-04-19	1985-08-13	American Home Products Corporation	2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
CA1227304A (en)	1984-08-01	1987-09-29	Raymond C. Francis	Delignification of pulp
GB8902209D0 (en)	1989-02-01	1989-03-22	Wyeth John And Brother Limited	Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6342533B1 (en) *	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
US6197828B1 (en) *	1998-12-01	2001-03-06	Sepracor, Inc.	Derivatives of (+)-venlafaxine and methods of preparing and using the same
JP2003521470A (ja)	1999-04-06	2003-07-15	セプラコアインコーポレーテッド	ベンラファキシンの誘導体とその調製および使用方法
AU5738700A (en)	1999-06-15	2001-01-02	American Home Products Corporation	Enantiomers of o-desmethyl venlafaxine
AU2001281967A1 (en)	2000-07-18	2002-01-30	Bayer Aktiengesellschaft	Regulation of human desc1-like serine protease
NZ539791A (en) *	2001-02-12	2006-11-30	Wyeth Corp	Novel succinate salt of o-desmethyl-venlafaxine
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine

2002
- 2002-03-12 UA UA20040705306A patent/UA80543C2/uk unknown
- 2002-11-26 US US10/304,871 patent/US6689912B2/en not_active Expired - Fee Related
- 2002-11-27 TW TW091134427A patent/TWI260982B/zh not_active IP Right Cessation
- 2002-12-03 CN CNB028242386A patent/CN1319934C/zh not_active Expired - Fee Related
- 2002-12-03 PT PT02804479T patent/PT1451143E/pt unknown
- 2002-12-03 RU RU2004120284/04A patent/RU2317286C2/ru not_active IP Right Cessation
- 2002-12-03 PL PL02369299A patent/PL369299A1/xx unknown
- 2002-12-03 IL IL16225302A patent/IL162253A0/xx active IP Right Grant
- 2002-12-03 DE DE60228118T patent/DE60228118D1/de not_active Expired - Lifetime
- 2002-12-03 BR BR0214701-7A patent/BR0214701A/pt not_active Application Discontinuation
- 2002-12-03 AU AU2002357049A patent/AU2002357049B2/en not_active Ceased
- 2002-12-03 HU HU0402269A patent/HUP0402269A3/hu active IP Right Revival
- 2002-12-03 DK DK02804479T patent/DK1451143T3/da active
- 2002-12-03 CA CA2466779A patent/CA2466779C/en not_active Expired - Lifetime
- 2002-12-03 ES ES02804479T patent/ES2311647T4/es not_active Expired - Lifetime
- 2002-12-03 EP EP02804479A patent/EP1451143B9/de not_active Expired - Lifetime
- 2002-12-03 WO PCT/US2002/038403 patent/WO2003048104A1/en active Application Filing
- 2002-12-03 MX MXPA04005309A patent/MXPA04005309A/es active IP Right Grant
- 2002-12-03 JP JP2003549297A patent/JP4342312B2/ja not_active Expired - Fee Related
- 2002-12-03 NZ NZ533316A patent/NZ533316A/en unknown
- 2002-12-03 AT AT02804479T patent/ATE403641T1/de not_active IP Right Cessation
- 2002-12-03 KR KR1020047008512A patent/KR100939650B1/ko not_active Expired - Fee Related
- 2002-12-03 AR ARP020104669A patent/AR037622A1/es unknown
- 2002-12-03 SI SI200230743T patent/SI1451143T1/sl unknown
2003
- 2003-12-31 US US10/750,196 patent/US20040158101A1/en not_active Abandoned
2004
- 2004-05-31 IL IL162253A patent/IL162253A/en not_active IP Right Cessation
- 2004-06-01 CO CO04050957A patent/CO5580816A2/es active IP Right Grant
- 2004-06-04 EC EC2004005135A patent/ECSP045135A/es unknown
- 2004-06-25 NO NO20042680A patent/NO20042680L/no not_active Application Discontinuation
- 2004-07-01 ZA ZA2004/05250A patent/ZA200405250B/en unknown
2007
- 2007-06-01 US US11/756,772 patent/US7435854B2/en not_active Expired - Fee Related
2008
- 2008-09-11 US US12/208,990 patent/US20090018365A1/en not_active Abandoned
- 2008-09-11 IL IL194034A patent/IL194034A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0402269A2 (hu)	2005-02-28
ES2311647T4 (es)	2009-11-10
IL162253A (en)	2009-02-11
AR037622A1 (es)	2004-11-17
HUP0402269A3 (en)	2010-06-28
ECSP045135A (es)	2004-07-23
ZA200405250B (en)	2005-12-28
US20070225525A1 (en)	2007-09-27
TWI260982B (en)	2006-09-01
CN1625546A (zh)	2005-06-08
NO20042680L (no)	2004-06-25
CA2466779C (en)	2013-11-19
WO2003048104A1 (en)	2003-06-12
RU2317286C2 (ru)	2008-02-20
MXPA04005309A (es)	2004-09-13
AU2002357049A1 (en)	2003-06-17
US7435854B2 (en)	2008-10-14
PT1451143E (pt)	2008-10-21
EP1451143B1 (de)	2008-08-06
TW200301102A (en)	2003-07-01
EP1451143B9 (de)	2009-08-12
CO5580816A2 (es)	2005-11-30
PL369299A1 (en)	2005-04-18
HK1065778A1 (en)	2005-03-04
IL194034A (en)	2010-12-30
AU2002357049B2 (en)	2009-07-16
KR100939650B1 (ko)	2010-02-05
ES2311647T3 (es)	2009-02-16
CA2466779A1 (en)	2003-06-12
KR20050044671A (ko)	2005-05-12
JP2005511681A (ja)	2005-04-28
RU2004120284A (ru)	2005-04-10
IL162253A0 (en)	2005-11-20
US20090018365A1 (en)	2009-01-15
US20030105358A1 (en)	2003-06-05
NZ533316A (en)	2005-12-23
BR0214701A (pt)	2004-08-31
CN1319934C (zh)	2007-06-06
JP4342312B2 (ja)	2009-10-14
US20040158101A1 (en)	2004-08-12
EP1451143A1 (de)	2004-09-01
SI1451143T1 (sl)	2008-12-31
DE60228118D1 (de)	2008-09-18
US6689912B2 (en)	2004-02-10
UA80543C2 (en)	2007-10-10
DK1451143T3 (da)	2008-11-10

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Date	Code	Title	Description
2009-02-15	UEP	Publication of translation of european patent specification	Ref document number: 1451143 Country of ref document: EP
2010-09-15	REN	Ceased due to non-payment of the annual fee

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2009-02-15

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Publication of translation of european patent specification

Ref document number: 1451143

Country of ref document: EP

2010-09-15

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Ceased due to non-payment of the annual fee