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ATE399884T1 - Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden - Google Patents

Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Info

Publication number
ATE399884T1
ATE399884T1 AT05732398T AT05732398T ATE399884T1 AT E399884 T1 ATE399884 T1 AT E399884T1 AT 05732398 T AT05732398 T AT 05732398T AT 05732398 T AT05732398 T AT 05732398T AT E399884 T1 ATE399884 T1 AT E399884T1
Authority
AT
Austria
Prior art keywords
present
encoding
reaction
decoding
coding
Prior art date
Application number
AT05732398T
Other languages
English (en)
Inventor
Kai Qin Lao
Mark T Reed
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE399884T1 publication Critical patent/ATE399884T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05732398T 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden ATE399884T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55616204P 2004-03-24 2004-03-24
US55622404P 2004-03-24 2004-03-24
US55616304P 2004-03-24 2004-03-24
US55615704P 2004-03-24 2004-03-24
US63068104P 2004-11-24 2004-11-24

Publications (1)

Publication Number Publication Date
ATE399884T1 true ATE399884T1 (de) 2008-07-15

Family

ID=35064420

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05760637T ATE431433T1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen
AT05732398T ATE399884T1 (de) 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05760637T ATE431433T1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen

Country Status (6)

Country Link
US (2) US7601821B2 (de)
EP (3) EP2161346B1 (de)
JP (2) JP2007530048A (de)
AT (2) ATE431433T1 (de)
DE (2) DE602005014453D1 (de)
WO (2) WO2005094532A2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003275138A1 (en) * 2002-09-19 2004-04-08 Applied Biosystems, Llc. Methods and compositions for detecting targets
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US7601821B2 (en) 2004-03-24 2009-10-13 Applied Biosystems, Llc Encoding and decoding reactions for determining target molecules
US7364855B2 (en) * 2004-04-30 2008-04-29 Applera Corporation Methods and kits for methylation detection
WO2006076017A2 (en) * 2004-04-30 2006-07-20 Applera Corporation Methods and kits for identifying target nucleotides in mixed populations
US7575863B2 (en) * 2004-05-28 2009-08-18 Applied Biosystems, Llc Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
JP2008502352A (ja) * 2004-06-30 2008-01-31 アプレラ コーポレイション ポリヌクレオチドをライゲーションするための、方法、反応混合物およびキット
US7642055B2 (en) * 2004-09-21 2010-01-05 Applied Biosystems, Llc Two-color real-time/end-point quantitation of microRNAs (miRNAs)
CN101351542A (zh) * 2005-07-15 2009-01-21 阿普尔拉公司 液体加工装置和方法
ATE489473T1 (de) * 2005-07-15 2010-12-15 Life Technologies Corp Analyse von boten-rna und mikro-rna im gleichen reaktionsansatz
US9285297B2 (en) * 2005-08-22 2016-03-15 Applied Biosystems, Llc Device, system, and method for depositing processed immiscible-fluid-discrete-volumes
US20070111226A1 (en) * 2005-08-24 2007-05-17 Applera Corporation Method to Quantify siRNAs, miRNAs and Polymorphic miRNAs
WO2007133703A2 (en) * 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
US8597938B2 (en) * 2007-10-12 2013-12-03 Qiagen Sciences Llc System for providing control reactions for real time RT-PCR
WO2009100449A1 (en) * 2008-02-08 2009-08-13 Fluidigm Corporation Dynamic array assay methods
EP2326732A4 (de) * 2008-08-26 2012-11-14 Fluidigm Corp Testverfahren für erhöhten durchsatz von proben und/oder targets
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
JP5608998B2 (ja) * 2009-03-31 2014-10-22 東洋紡株式会社 保存安定性に優れた核酸増幅検出試薬キット
US9976177B2 (en) * 2009-04-01 2018-05-22 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (CLPA)
KR101770363B1 (ko) 2009-04-02 2017-08-22 플루이다임 코포레이션 표적 핵산의 바코딩을 위한 멀티 프라이머 증폭 방법
WO2011056866A2 (en) 2009-11-05 2011-05-12 Epicentre Technologies Corporation Methods and kits for 3'-end-tagging of rna
SG10201407883PA (en) * 2009-12-07 2015-01-29 Illumina Inc Multi-sample indexing for multiplex genotyping
EP2534263B1 (de) * 2010-02-09 2020-08-05 Unitaq Bio Verfahren und zusammensetzungen zur universellen erkennung von nukleinsäuren
CA2810931C (en) 2010-09-24 2018-04-17 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
WO2012054933A2 (en) * 2010-10-22 2012-04-26 Fluidigm Corporation Universal probe assay methods
US20120288857A1 (en) * 2011-02-03 2012-11-15 Fluidigm Corporation Multifunctional probe-primers
WO2012142003A2 (en) 2011-04-15 2012-10-18 Life Technologies Corporation Chemical ligation
WO2012154876A1 (en) 2011-05-09 2012-11-15 Fluidigm Corporation Probe based nucleic acid detection
KR102085242B1 (ko) 2011-05-17 2020-03-05 디엑스테리티 다이아그노스틱스 인코포레이티드 표적 핵산 검출을 위한 방법 및 조성물
US9074204B2 (en) 2011-05-20 2015-07-07 Fluidigm Corporation Nucleic acid encoding reactions
EP2764100A4 (de) * 2011-10-03 2015-09-16 Univ Florida Schnelle und zuverlässige detektion von infektionserregern
US10150841B2 (en) * 2011-12-30 2018-12-11 University Of Washington Through Its Center For Commercialization Chromophoric polymer dots with narrow-band emission
WO2013106807A1 (en) 2012-01-13 2013-07-18 Curry John D Scalable characterization of nucleic acids by parallel sequencing
EP2809813B1 (de) * 2012-02-03 2018-08-08 California Institute of Technology Signalcodierung und -decodierung bei biochemischen multiplextests
CN104204228A (zh) 2012-02-14 2014-12-10 康奈尔大学 使用组合的核酸酶、连接和聚合酶反应用于核酸序列的相对定量、表达或拷贝变化的方法
EP2852682B1 (de) 2012-05-21 2017-10-04 Fluidigm Corporation Einzelpartikelanalyse von teilchenpopulationen
US9791372B2 (en) 2012-08-03 2017-10-17 California Institute Of Technology Multiplexing and quantification in PCR with reduced hardware and requirements
EP2971172B1 (de) 2013-03-14 2019-07-24 Cornell University Verfahren zur relativen quantifizierung von veränderungen in einer dna-methylierung mit kombinierten nuklease-, ligations- und polymerasereaktionen
WO2015153571A2 (en) 2014-04-01 2015-10-08 Cornell University Detection of dna methylation using combined nuclease ligation reactions
AU2015274660B2 (en) 2014-06-10 2020-07-16 Dxterity Diagnostics Incorporated Devices and methods for collecting and stabilizing biological samples
PT3204520T (pt) 2014-10-08 2020-04-16 Univ Cornell Método de identificação e quantificação da expressão de ácidos nucleicos, variantes de splicing, translocação, número de cópias ou alterações de metilação
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
EP3390658B1 (de) 2015-12-16 2022-08-03 Standard BioTools Inc. High-level-multiplexamplifikation
CN108026568A (zh) * 2016-01-31 2018-05-11 阿费梅特里克斯公司 通过结合条形码标记的多核苷酸探针进行核酸分析
US10066263B2 (en) 2016-06-17 2018-09-04 California Institute Of Technology Nucleic acid reactions and related methods and compositions
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5494810A (en) * 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
ATE173767T1 (de) * 1992-04-03 1998-12-15 Perkin Elmer Corp Proben zusammensetzung und verfahren
WO1996015271A1 (en) 1994-11-16 1996-05-23 Abbott Laboratories Multiplex ligations-dependent amplification
GB9609441D0 (en) * 1996-05-04 1996-07-10 Zeneca Ltd Process
EP2369007B1 (de) * 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Erkennung von Nukleinsäuresequenz-Unterschieden mittels der gleichzeitigen Ligaseerkennungs- und Polymerasekettenreaktion
US7014994B1 (en) * 1999-03-19 2006-03-21 Cornell Research Foundation,Inc. Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
US6331393B1 (en) * 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
US6618679B2 (en) * 2000-01-28 2003-09-09 Althea Technologies, Inc. Methods for analysis of gene expression
AU2001265121A1 (en) * 2000-05-30 2001-12-11 Applera Corporation Methods for detecting target nucleic acids using coupled ligation and amplification
US6620586B2 (en) * 2001-02-20 2003-09-16 Applied Gene Technologies, Inc. Methods and compositions for analyzing nucleic acids
US20030119004A1 (en) 2001-12-05 2003-06-26 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
EP1319718A1 (de) * 2001-12-14 2003-06-18 Keygene N.V. Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen
US20060088826A1 (en) * 2001-12-28 2006-04-27 Van Eijk Michael Josephus Ther Discrimination and detection of target nucleotide sequences using mass spectrometry
US6960436B2 (en) * 2002-02-06 2005-11-01 Epigenomics Ag Quantitative methylation detection in DNA samples
US7176002B2 (en) * 2002-05-16 2007-02-13 Applera Corporation Universal-tagged oligonucleotide primers and methods of use
AU2003275138A1 (en) * 2002-09-19 2004-04-08 Applied Biosystems, Llc. Methods and compositions for detecting targets
JP2006500033A (ja) * 2002-09-19 2006-01-05 アプレラ コーポレイション 標的を検出するための方法および組成物
US20040235005A1 (en) * 2002-10-23 2004-11-25 Ernest Friedlander Methods and composition for detecting targets
US20040110134A1 (en) * 2002-12-05 2004-06-10 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
WO2005026389A2 (en) 2003-08-29 2005-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
US7601821B2 (en) 2004-03-24 2009-10-13 Applied Biosystems, Llc Encoding and decoding reactions for determining target molecules

Also Published As

Publication number Publication date
EP1730312A2 (de) 2006-12-13
US7604937B2 (en) 2009-10-20
US20050272071A1 (en) 2005-12-08
US7601821B2 (en) 2009-10-13
WO2005094532A2 (en) 2005-10-13
EP1727913B1 (de) 2009-05-13
EP1727913A2 (de) 2006-12-06
DE602005014453D1 (de) 2009-06-25
EP1727913B8 (de) 2009-08-19
WO2005098040A2 (en) 2005-10-20
ATE431433T1 (de) 2009-05-15
EP2161346B1 (de) 2013-06-19
DE602005007874D1 (de) 2008-08-14
EP1730312B1 (de) 2008-07-02
EP2161346A1 (de) 2010-03-10
WO2005098040A3 (en) 2006-03-23
WO2005094532A3 (en) 2005-12-22
WO2005098040A8 (en) 2005-12-01
JP2007530048A (ja) 2007-11-01
JP2007530051A (ja) 2007-11-01
US20050260640A1 (en) 2005-11-24

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