ATE398448T1 - Herstellung von weichgelatinekapseln - Google Patents
Herstellung von weichgelatinekapselnInfo
- Publication number
- ATE398448T1 ATE398448T1 AT00103110T AT00103110T ATE398448T1 AT E398448 T1 ATE398448 T1 AT E398448T1 AT 00103110 T AT00103110 T AT 00103110T AT 00103110 T AT00103110 T AT 00103110T AT E398448 T1 ATE398448 T1 AT E398448T1
- Authority
- AT
- Austria
- Prior art keywords
- soft gelatin
- gelatin capsules
- production
- solvent
- capsules
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Organic Chemistry (AREA)
- Medical Informatics (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Cosmetics (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4332931 | 1993-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE398448T1 true ATE398448T1 (de) | 2008-07-15 |
Family
ID=6498793
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94115081T ATE198041T1 (de) | 1993-09-28 | 1994-09-24 | Herstellung von weichgelatinekapseln |
AT00103110T ATE398448T1 (de) | 1993-09-28 | 1994-09-24 | Herstellung von weichgelatinekapseln |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94115081T ATE198041T1 (de) | 1993-09-28 | 1994-09-24 | Herstellung von weichgelatinekapseln |
Country Status (31)
Country | Link |
---|---|
US (4) | US5985321A (de) |
EP (3) | EP1029538A3 (de) |
JP (1) | JP3071642B2 (de) |
KR (1) | KR100200174B1 (de) |
CN (2) | CN1182842C (de) |
AT (2) | ATE198041T1 (de) |
AU (1) | AU690571B2 (de) |
CA (3) | CA2132933C (de) |
CZ (1) | CZ290314B6 (de) |
DE (2) | DE69435104D1 (de) |
DK (2) | DK1033128T4 (de) |
ES (2) | ES2308955T5 (de) |
FI (1) | FI120718B (de) |
FR (1) | FR2710532B1 (de) |
GB (1) | GB2282586B (de) |
GR (1) | GR3035179T3 (de) |
HK (1) | HK1078478A1 (de) |
HU (2) | HU228201B1 (de) |
IL (1) | IL111067A (de) |
IT (1) | IT1274931B (de) |
NO (1) | NO312334B1 (de) |
NZ (1) | NZ264536A (de) |
PE (1) | PE31295A1 (de) |
PL (1) | PL178884B1 (de) |
PT (2) | PT1033128E (de) |
RU (1) | RU2140783C1 (de) |
SG (1) | SG46531A1 (de) |
SI (2) | SI0649651T1 (de) |
SK (2) | SK285204B6 (de) |
TW (1) | TW438609B (de) |
ZA (1) | ZA947567B (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE132036T1 (de) * | 1992-01-17 | 1996-01-15 | Alfatec Pharma Gmbh | Verfahren zur herstellung von weichgelatinekapseln nach einem tropfverfahren |
US6204243B1 (en) | 1993-09-01 | 2001-03-20 | Novatis Ag | Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis |
ATE198041T1 (de) | 1993-09-28 | 2000-12-15 | Scherer Gmbh R P | Herstellung von weichgelatinekapseln |
MY129435A (en) * | 1994-10-26 | 2007-04-30 | Novartis Ag | Pharmaceutical microemulsion preconcentrates |
GB2308545B (en) * | 1994-10-26 | 1999-06-02 | Novartis Ag | Pharmaceutical microemulsion preconcentrates |
US7205279B2 (en) * | 1995-10-25 | 2007-04-17 | Novartis Ag | Pharmaceutical compositions |
US5603951A (en) * | 1994-11-09 | 1997-02-18 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin-containing soft capsule compositions |
NZ280689A (en) * | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
JPH1071186A (ja) * | 1996-08-29 | 1998-03-17 | Shionogi & Co Ltd | カプセルのバンドシール形成方法 |
TR199901686T2 (xx) * | 1997-01-30 | 1999-09-21 | Norvartis Ag | Esasen ya�s�z farmakolojik kompozisyonlar� i�eren sert jelatin kaps�ller. |
PT982035E (pt) * | 1998-08-18 | 2004-08-31 | Panacea Biotec Ltd | Composicao de ciclosporina compreendendo um veiculo hidrofilo |
RU2219911C2 (ru) * | 1998-11-17 | 2003-12-27 | Ф.Хоффманн-Ля Рош Аг | Способ изготовления заполненных жидкостью капсул |
US7026290B1 (en) | 1998-12-30 | 2006-04-11 | Dexcel Ltd. | Dispersible concentrate for the delivery of cyclosprin |
US20030104048A1 (en) * | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
EP1200091B1 (de) * | 1999-08-03 | 2008-07-02 | Lilly Icos LLC | Pharmazeutische zusammensetzung enthaltend tadalafil |
JP4601100B2 (ja) * | 1999-11-08 | 2010-12-22 | 三生医薬株式会社 | マスティックの油液を内包した軟カプセル |
US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
BR0013813A (pt) | 2000-09-18 | 2002-04-30 | Rpg Life Sciences Ltd | Formulação auto-emulsificável possuindo atividades bioabsorventes e imunossupressoras |
PT1292281E (pt) * | 2000-10-12 | 2004-11-30 | Boehringer Ingelheim Pharma | Novos pos para inalacao contendo tiotropio |
SK6572003A3 (en) * | 2000-10-31 | 2003-10-07 | Boehringer Ingelheim Pharma | Oral self-emulsifying formulations of pyranone protease inhibitors |
JP4214350B2 (ja) * | 2001-01-15 | 2009-01-28 | 日本電気株式会社 | 携帯電話のsimカード取り付け構造 |
US20030138483A1 (en) * | 2001-05-25 | 2003-07-24 | Sergio Petriconi | Soft elastic capsules and compositions thereof |
US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
US20040013732A1 (en) * | 2001-09-25 | 2004-01-22 | Michael Farber | Starch-based delivery system for creatine |
AU2002333098B2 (en) * | 2001-10-19 | 2006-03-16 | Isotechnika Pharma Inc. | Novel cyclosporin analog microemulsion preconcentrates |
US6752953B2 (en) * | 2001-12-03 | 2004-06-22 | Yung Shin Pharmaceutical Co., Ltd. | Method for manufacturing hard non-gelatin pharmaceutical capsules |
KR20030062894A (ko) * | 2002-01-21 | 2003-07-28 | 주식회사 보창 | 소프트젤라틴캡슐제조기의 성형드럼 냉각장치 |
US7067150B2 (en) | 2002-04-16 | 2006-06-27 | Scepter Holdings, Inc. | Delivery systems for functional ingredients |
MXPA05001191A (es) * | 2002-07-29 | 2005-09-12 | Johnson & Johnson | Metodos y formas de dosificacion para la administracion controlada de paliperidona. |
US7763280B2 (en) * | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
KR100525234B1 (ko) * | 2003-02-19 | 2005-10-28 | 한국유나이티드제약 주식회사 | 사이클로스포린 함유 연질캅셀제 및 그 제조방법 |
US7134978B2 (en) * | 2003-07-28 | 2006-11-14 | Sagittarius Life Science Corporation | Seamless BB paintball |
USD520635S1 (en) | 2003-09-16 | 2006-05-09 | Novartis Ag | Combine capsule and tablets |
USD530814S1 (en) | 2003-09-16 | 2006-10-24 | Novartis Ag | Combined capsule and tablets |
US7247010B2 (en) * | 2003-10-01 | 2007-07-24 | Technophar Equipment & Service Limited | Servo control for capsule making machine |
FR2861992B1 (fr) * | 2003-11-10 | 2007-07-20 | Sanofi Synthelabo | Composition pharmaceutique destinee a l'administration orale d'un derive de pyrazole-3-carboxamide. |
US7934454B2 (en) * | 2003-11-12 | 2011-05-03 | Kee Action Sports I Llc | Projectile, projectile core, and method of making |
US20050175686A1 (en) * | 2004-02-11 | 2005-08-11 | Ramachandran Radhakrishnan | Drug delivery system using a solubilized gelatin shell composition and unit dose drug delivery using a special shape soft gelatin capsule |
JP2005255677A (ja) * | 2004-02-12 | 2005-09-22 | Nof Corp | シクロスポリン製剤 |
US20080160086A1 (en) * | 2004-02-19 | 2008-07-03 | Scepter Holdings, Inc. | Delivery Systems For Calcium |
US20060153824A1 (en) * | 2005-01-13 | 2006-07-13 | Everett Laboratories, Inc. | Methods and kits for co-administration of nutritional supplements |
EP1885342B8 (de) * | 2005-03-21 | 2016-06-22 | Teva Czech Industries s.r.o. | Kristallisationsinhibitor und dessen verwendung in gelatinekapseln |
US20060275361A1 (en) * | 2005-06-03 | 2006-12-07 | Cadbury Adams Usa Llc. | Rapidly dissolving gelatin compositions and products made therefrom |
CA2629714A1 (en) | 2005-11-14 | 2007-05-24 | Ariad Gene Therapeutics, Inc. | Administration of an mtor inhibitor to treat patients with cancer |
CN1919194A (zh) * | 2006-08-17 | 2007-02-28 | 刘瑜玲 | 西罗莫司的液体组合物 |
CA2677036A1 (en) * | 2007-03-06 | 2008-09-12 | Bioriginal Food & Science Corp. | Soft gelatin capsule shells containing oil soluble flavoring and methods of making the same |
US20090110724A1 (en) * | 2007-10-31 | 2009-04-30 | Everett Laboratories, Inc. | Compositions and methods for treatment of pain |
MX2011002828A (es) | 2008-09-16 | 2011-04-05 | Boehringer Ingelheim Int | Formas cristalinas de un derivado de 2-tiazolil-4-quinolinil-oxi, un potente inhibidor de hcv. |
CN102292078A (zh) | 2008-11-11 | 2011-12-21 | 得克萨斯大学体系董事会 | 哺乳动物雷帕霉素靶蛋白的抑制 |
AU2010270783B2 (en) | 2009-07-07 | 2013-06-27 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition for a hepatitis C viral protease inhibitor |
US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
US8530497B2 (en) | 2010-03-11 | 2013-09-10 | Boehringer Ingelheim International Gmbh | Crystalline salts of a potent HCV inhibitor |
GB201006012D0 (en) * | 2010-04-09 | 2010-05-26 | Ayanda As | Composition |
US20120049410A1 (en) * | 2010-07-19 | 2012-03-01 | Carlos Salazar Altamar | Apparatus and process for making soft gel capsules |
US8598183B2 (en) | 2010-09-30 | 2013-12-03 | Boehringer Ingelheim International Gmbh | Solid state forms of a potent HCV inhibitor |
US20120107395A1 (en) * | 2010-11-01 | 2012-05-03 | Viva Pharmaceutical Inc. | Probiotic Soft Gel Compositions |
US8621764B2 (en) | 2011-03-16 | 2014-01-07 | John PUCKETT | Gelatin capsule formulation and drying system |
TW201302761A (zh) | 2011-04-04 | 2013-01-16 | Gilead Sciences Inc | Hiv抑制劑之固態形式 |
CN103732255B (zh) * | 2011-09-02 | 2016-04-06 | 富士胶片株式会社 | 软胶囊制剂、软胶囊制剂用组合物及软胶囊制剂的制造方法 |
US20130261134A1 (en) | 2012-03-30 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Mesylate salt forms of a potent hcv inhibitor |
WO2014055618A1 (en) | 2012-10-03 | 2014-04-10 | Gilead Sciences, Inc. | Solid state forms of hiv inhibitor: hemi-succinate of (2s)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid) |
WO2014160328A1 (en) | 2013-03-13 | 2014-10-02 | The Board Of Regents Of The University Of Texas System | Mtor inhibitors for prevention of intestinal polyp growth |
CN103315975B (zh) * | 2013-06-05 | 2015-09-02 | 天津科技大学 | 一种明胶-CaCO3矿物质胶囊壳及其制备方法 |
ES2797374T3 (es) * | 2013-07-25 | 2020-12-02 | Neuren Pharmaceuticals Ltd | Compuestos bicíclicos neuroprotectores y métodos para su uso en el tratamiento de trastornos del espectro autista y trastornos del neurodesarrollo |
CA3206208A1 (en) | 2013-12-31 | 2015-07-09 | Rapamycin Holdings, Llc | Oral rapamycin nanoparticle preparations and use |
US9700544B2 (en) | 2013-12-31 | 2017-07-11 | Neal K Vail | Oral rapamycin nanoparticle preparations |
EP4066822A1 (de) * | 2015-08-19 | 2022-10-05 | Vivus, Inc. | Pharmazeutische formulierungen |
CN112240659A (zh) * | 2020-10-17 | 2021-01-19 | 温州桑盾信息科技有限公司 | 一种胶囊机安全防护用自动降温机构 |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198391A (en) * | 1973-07-20 | 1980-04-15 | R. P. Scherer Ltd. | Pharmaceutical compositions |
US3870547A (en) | 1974-01-24 | 1975-03-11 | Owens Corning Fiberglass Corp | Starch coated fibers for embedding in resin matrix forming materials and composites so formed |
BE825842A (fr) * | 1974-02-22 | 1975-08-21 | Compositions pharmaceutiques comprenant de la digoxine | |
GB1508770A (en) | 1974-04-01 | 1978-04-26 | Scherer Ltd R | Pharmaceutical compositions |
US4067960A (en) * | 1975-06-20 | 1978-01-10 | R. P. Scherer Limited | Pharmaceutical compositions containing cardiac glycoside |
SE445174B (sv) * | 1978-03-07 | 1986-06-09 | Sandoz Ag | Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans |
JPS5933018B2 (ja) * | 1980-03-17 | 1984-08-13 | 森下仁丹株式会社 | 高融点物質のマイクロカプセル製造方法とその製造装置 |
DE3237814A1 (de) * | 1982-10-12 | 1984-04-12 | Warner-Lambert Co., 07950 Morris Plains, N.J. | Wasserfreie emulsionen und verwendung derselben |
GB8305693D0 (en) * | 1983-03-02 | 1983-04-07 | Scherer Ltd R P | Pharmaceutical compositions |
DE3307353C2 (de) | 1983-03-02 | 1985-01-31 | R.P. Scherer GmbH, 6930 Eberbach | Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung |
DE3406497A1 (de) | 1984-02-23 | 1985-09-05 | Mueller Bernhard Willi Werner | Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung |
US4609403A (en) * | 1984-03-12 | 1986-09-02 | Warner-Lambert Company | Foam soft gelatin capsules and their method of manufacture |
US4713246A (en) | 1984-03-19 | 1987-12-15 | Bristol-Myers Company | Etoposide oral dosage form |
DE3579384D1 (de) * | 1984-07-24 | 1990-10-04 | Scherer Gmbh R P | Oxytetracyclin-hc1-weichgelatinekapseln und verfahren zu ihrer herstellung. |
DE3445237C1 (de) * | 1984-12-12 | 1986-06-05 | R.P. Scherer GmbH, 6930 Eberbach | Weichgelatinekapseln und Verfahren zu ihrer Herstellung |
DE3529694A1 (de) | 1985-08-20 | 1987-02-26 | Scherer Gmbh R P | Gelatinekapseln und verfahren zu ihrer herstellung |
JPS62207460A (ja) | 1986-03-07 | 1987-09-11 | 株式会社三協 | ゼラチンカプセルの製造装置におけるゼラチンシ−ト成型装置 |
ATE59552T1 (de) | 1986-04-05 | 1991-01-15 | Scherer Gmbh R P | Gelatinekapseln mit gesteuerter wirkstofffreisetzung und verfahren zur herstellung derselben. |
DE3629386A1 (de) * | 1986-08-29 | 1988-03-03 | Scherer Gmbh R P | Gelatinekapseln und verfahren zu ihrer herstellung |
US4927638A (en) * | 1986-10-08 | 1990-05-22 | Bristol-Myers Company | Etoposide solutions |
US5154930A (en) * | 1987-03-05 | 1992-10-13 | The Liposome Company, Inc. | Pharmacological agent-lipid solution preparation |
JPS63309264A (ja) | 1987-06-10 | 1988-12-16 | Kamata Seisakusho:Kk | ソフトカプセル製造機 |
US4817367A (en) * | 1987-08-10 | 1989-04-04 | Sankyo Co., Ltd. | Apparatus for manufacturing gelatin capsule and method therefor |
GB8721455D0 (en) | 1987-09-11 | 1987-10-21 | Lilly Industries Ltd | Capsules |
HU205010B (en) * | 1987-09-15 | 1992-03-30 | Sandoz Ag | Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity |
CA1326995C (en) * | 1988-01-29 | 1994-02-15 | Kozo Kurihara | Cyclosporin compositions |
US5376381A (en) * | 1988-02-25 | 1994-12-27 | The Liposome Company, Inc. | Integrity protected gelatin |
KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
US4935293A (en) | 1988-10-25 | 1990-06-19 | Unifi, Inc. | Continuous multi-filament polyester substrate readily adherable to a vinyl sheet |
US4935243A (en) * | 1988-12-19 | 1990-06-19 | Pharmacaps, Inc. | Chewable, edible soft gelatin capsule |
US5532002A (en) * | 1989-08-17 | 1996-07-02 | Cortecs Limited | Gelatin pharmaceutical formulations |
CA2063791C (en) * | 1989-08-17 | 2000-12-19 | Michael John Story | Hard gelatine capsule containing fat-soluble nutrients. |
US5178877A (en) * | 1991-01-04 | 1993-01-12 | Abbott Laboratories | Encapsulated renin inhibitor composition |
US6262022B1 (en) * | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
US5224294A (en) * | 1991-07-25 | 1993-07-06 | E. I. Du Pont De Nemours And Company | Hydroponic growth system |
US5200191A (en) * | 1991-09-11 | 1993-04-06 | Banner Gelatin Products Corp. | Softgel manufacturing process |
US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
DE4201178C2 (de) * | 1992-01-17 | 1995-12-07 | Alfatec Pharma Gmbh | Verfahren zur Herstellung von Weichgelatinekapseln nach einem Tropfverfahren |
EP0573978B1 (de) * | 1992-06-12 | 1999-04-21 | Kao Corporation | Badezusatzzusammensetzung enthaltend oberflächenaktive Mittel enthaltende nahtlose Kapsel und Verfahren zur Herrstellung der Kapsel |
US5626872A (en) * | 1992-06-16 | 1997-05-06 | Roemmers S.A.I.C.F. | Pharmaceutical soft capsules containing lysine clonixinate and a process for their preparation |
CZ278863B6 (en) | 1992-09-07 | 1994-07-13 | Galena | Medicinal preparations with n-methylated cyclic undecapeptides |
US5376293A (en) * | 1992-09-14 | 1994-12-27 | State Of South Dakota As Represented By The Department Of Transportation | Deicer |
GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
JPH06157916A (ja) | 1992-11-30 | 1994-06-07 | Warner Lambert Kk | カプセル硬皮膜組成物 |
US5376688A (en) * | 1992-12-18 | 1994-12-27 | R. P. Scherer Corporation | Enhanced solubility pharmaceutical solutions |
US5431916A (en) * | 1993-04-29 | 1995-07-11 | The Procter & Gamble Company | Pharmaceutical compositions and process of manufacture thereof |
CH686761A5 (de) | 1993-05-27 | 1996-06-28 | Sandoz Ag | Galenische Formulierungen. |
CN1077800C (zh) | 1993-07-01 | 2002-01-16 | 韩美药品工业株式会社 | 环孢菌素软胶囊组合物 |
US5505961A (en) * | 1993-08-05 | 1996-04-09 | R. P. Scherer Corporation | Gelatin capsules containing a highly concentrated acetaminophen solution |
US6204243B1 (en) * | 1993-09-01 | 2001-03-20 | Novatis Ag | Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis |
IL110752A (en) * | 1993-09-13 | 2000-07-26 | Abbott Lab | Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor |
ATE198041T1 (de) | 1993-09-28 | 2000-12-15 | Scherer Gmbh R P | Herstellung von weichgelatinekapseln |
KR0146671B1 (ko) * | 1994-02-25 | 1998-08-17 | 김충환 | 사이클로스포린-함유 분말 조성물 |
US5641512A (en) * | 1995-03-29 | 1997-06-24 | The Procter & Gamble Company | Soft gelatin capsule compositions |
US5614217A (en) * | 1995-06-07 | 1997-03-25 | R.P. Scherer Corporation | Capsule shell formulation to produce brittle capsules |
NZ280689A (en) * | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
US5958876A (en) | 1996-06-19 | 1999-09-28 | Novartis Ag | Cyclosporin-containing pharmaceutical compositions |
ATE222502T1 (de) * | 1996-07-30 | 2002-09-15 | Novartis Ag | Kombinationspräparat mit hemmender wirkung auf die abstossung von transplantaten, autoimmunerkrankungen und entzündungen, welches cyclosporin a und 40-0-(2-hydroxyethyl)-rapamycin enthält |
US5798333A (en) * | 1996-09-17 | 1998-08-25 | Sherman; Bernard C. | Water-soluble concentrates containing cyclosporins |
FR2755368B1 (fr) * | 1996-11-04 | 1999-03-19 | Oreal | Composition rincable pour le soin de la peau |
-
1994
- 1994-09-24 AT AT94115081T patent/ATE198041T1/de active
- 1994-09-24 EP EP00103109A patent/EP1029538A3/de not_active Withdrawn
- 1994-09-24 DE DE69435104T patent/DE69435104D1/de not_active Expired - Lifetime
- 1994-09-24 PT PT00103110T patent/PT1033128E/pt unknown
- 1994-09-24 EP EP00103110A patent/EP1033128B2/de not_active Expired - Lifetime
- 1994-09-24 SI SI9430349T patent/SI0649651T1/xx unknown
- 1994-09-24 ES ES00103110T patent/ES2308955T5/es not_active Expired - Lifetime
- 1994-09-24 DK DK00103110.3T patent/DK1033128T4/da active
- 1994-09-24 DK DK94115081T patent/DK0649651T3/da active
- 1994-09-24 ES ES94115081T patent/ES2152281T3/es not_active Expired - Lifetime
- 1994-09-24 SI SI9430487T patent/SI1033128T2/sl unknown
- 1994-09-24 EP EP94115081A patent/EP0649651B1/de not_active Expired - Lifetime
- 1994-09-24 DE DE69426408T patent/DE69426408T2/de not_active Expired - Lifetime
- 1994-09-24 PT PT94115081T patent/PT649651E/pt unknown
- 1994-09-24 AT AT00103110T patent/ATE398448T1/de active
- 1994-09-26 IT ITRM940613A patent/IT1274931B/it active IP Right Grant
- 1994-09-26 AU AU74237/94A patent/AU690571B2/en not_active Expired
- 1994-09-26 FI FI944452A patent/FI120718B/fi not_active IP Right Cessation
- 1994-09-26 NO NO19943563A patent/NO312334B1/no not_active IP Right Cessation
- 1994-09-26 SK SK847-2002A patent/SK285204B6/sk not_active IP Right Cessation
- 1994-09-26 NZ NZ264536A patent/NZ264536A/en not_active IP Right Cessation
- 1994-09-26 GB GB9419353A patent/GB2282586B/en not_active Expired - Lifetime
- 1994-09-26 CA CA002132933A patent/CA2132933C/en not_active Expired - Lifetime
- 1994-09-26 CA CA002332631A patent/CA2332631C/en not_active Expired - Lifetime
- 1994-09-26 PL PL94305188A patent/PL178884B1/pl unknown
- 1994-09-26 PE PE1994251434A patent/PE31295A1/es not_active IP Right Cessation
- 1994-09-26 CA CA002302963A patent/CA2302963C/en not_active Expired - Lifetime
- 1994-09-26 RU RU94034106A patent/RU2140783C1/ru active
- 1994-09-26 SK SK1157-94A patent/SK284268B6/sk not_active IP Right Cessation
- 1994-09-26 IL IL11106794A patent/IL111067A/xx not_active IP Right Cessation
- 1994-09-26 SG SG1996005680A patent/SG46531A1/en unknown
- 1994-09-27 HU HU0105382A patent/HU228201B1/hu unknown
- 1994-09-27 CZ CZ19942360A patent/CZ290314B6/cs not_active IP Right Cessation
- 1994-09-27 HU HU9402772A patent/HU221681B1/hu unknown
- 1994-09-27 CN CNB941160211A patent/CN1182842C/zh not_active Expired - Lifetime
- 1994-09-27 CN CNB2004100974804A patent/CN100473377C/zh not_active Expired - Lifetime
- 1994-09-27 FR FR9411531A patent/FR2710532B1/fr not_active Expired - Lifetime
- 1994-09-27 JP JP6231107A patent/JP3071642B2/ja not_active Expired - Lifetime
- 1994-09-28 KR KR1019940024487A patent/KR100200174B1/ko not_active IP Right Cessation
- 1994-09-28 ZA ZA947567A patent/ZA947567B/xx unknown
- 1994-10-15 TW TW083109567A patent/TW438609B/zh not_active IP Right Cessation
-
1997
- 1997-04-29 US US08/841,734 patent/US5985321A/en not_active Expired - Lifetime
-
2000
- 2000-02-07 US US09/499,497 patent/US6589536B1/en not_active Expired - Fee Related
- 2000-10-17 US US09/690,401 patent/US6555132B1/en not_active Expired - Fee Related
- 2000-12-29 GR GR20000402869T patent/GR3035179T3/el unknown
-
2003
- 2003-05-13 US US10/437,098 patent/US7078054B2/en not_active Expired - Fee Related
-
2005
- 2005-11-21 HK HK05110510.5A patent/HK1078478A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE198041T1 (de) | Herstellung von weichgelatinekapseln | |
FI892762A0 (fi) | Foerfarande foer framstaellning av estrogenprodukt. | |
DE3650339D1 (de) | Herstellung von Urandioxid-Material. | |
DE69001609D1 (de) | Herstellung von niedrigviskosen fotografischen kleinteilchen-dispersionen in gelatine. | |
DE3876913D1 (de) | Herstellung von kohlenstoffhaltigen pulvern und ihre granulierung. | |
YU46641B (sh) | Postupak za dobijanje dvodelnih tvrdih želatinskih kapsula | |
DE68921340D1 (de) | Herstellung von epoxinitraten. | |
DE3877713D1 (de) | Herstellung von gelatinegelee-konfekten. | |
ATE110320T1 (de) | Herstellung von behältern. | |
ATE73643T1 (de) | Kapsel und verfahren zu ihrer herstellung. | |
KR860003831A (ko) | 프로스타글란딘 e 유도체의 안정한 제제의 제조방법 | |
ATA129283A (de) | Herstellung von neuen (4r*,5as*)2,4,5-trialkylch8204132231/8 | |
ATE1985T1 (de) | Verfahren zur herstellung von natriumhydrogencarbonat und chlorwasserstoff. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1033128 Country of ref document: EP |
|
UEP | Publication of translation of european patent specification |
Ref document number: 1033128 Country of ref document: EP |