[go: up one dir, main page]

ATE375387T1 - Modifiziertes polypeptid - Google Patents

Modifiziertes polypeptid

Info

Publication number
ATE375387T1
ATE375387T1 AT98928182T AT98928182T ATE375387T1 AT E375387 T1 ATE375387 T1 AT E375387T1 AT 98928182 T AT98928182 T AT 98928182T AT 98928182 T AT98928182 T AT 98928182T AT E375387 T1 ATE375387 T1 AT E375387T1
Authority
AT
Austria
Prior art keywords
allergenicity
modified
polypeptides
modified polypeptide
reducing
Prior art date
Application number
AT98928182T
Other languages
English (en)
Inventor
Arne Olsen
Tine Fatum
Heinz-Josef Deussen
Erwin Roggen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE375387T1 publication Critical patent/ATE375387T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24Organic nitrogen compounds
    • A21D2/26Proteins
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00Methods for preparing or baking dough
    • A21D8/02Methods for preparing dough; Treating dough prior to baking
    • A21D8/04Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/762Organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/783Microorganisms; Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1206Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/06Preparations for styling the hair, e.g. by temporary shaping or colouring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/10Preparations for permanently dyeing the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/37Polymers
    • C11D3/3703Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3719Polyamides or polyimides
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627Preparations containing enzymes, e.g. protease or amylase containing lipase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38654Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38681Chemically modified or immobilised enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00Preparations for removing hair or for aiding hair removal
    • A61Q9/02Shaving preparations
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D2111/00Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
    • C11D2111/10Objects to be cleaned
    • C11D2111/14Hard surfaces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
AT98928182T 1997-06-25 1998-06-22 Modifiziertes polypeptid ATE375387T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK75397 1997-06-25

Publications (1)

Publication Number Publication Date
ATE375387T1 true ATE375387T1 (de) 2007-10-15

Family

ID=8097153

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98928182T ATE375387T1 (de) 1997-06-25 1998-06-22 Modifiziertes polypeptid

Country Status (11)

Country Link
US (1) US6303752B1 (de)
EP (1) EP1002064B1 (de)
JP (1) JP2002516615A (de)
CN (1) CN100335624C (de)
AT (1) ATE375387T1 (de)
AU (1) AU751880B2 (de)
CA (1) CA2294567A1 (de)
DE (1) DE69838551T2 (de)
DK (1) DK1002064T3 (de)
ES (1) ES2296336T3 (de)
WO (1) WO1999000489A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) * 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
CA2325568A1 (en) 1998-03-26 1999-09-30 The Procter & Gamble Company Serine protease variants having amino acid substitutions
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
WO2001007577A2 (en) * 1999-07-22 2001-02-01 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
KR20020021395A (ko) * 1999-07-22 2002-03-20 데이비드 엠 모이어 입체적으로 보호된 clip 부위를 갖는 프로테아제콘쥬게이트
BR0012660A (pt) 1999-07-22 2002-04-09 Procter & Gamble Variante de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
CZ2002220A3 (cs) 1999-07-22 2002-05-15 The Procter & Gamble Company Varianty subtilisinové proteasy s delecemi a substitucemi aminokyselin v definovaných epitopových regionech
WO2003002716A2 (en) 2001-06-28 2003-01-09 Mountain View Pharmaceuticals, Inc. Polymer stabilized proteinases
KR100508369B1 (ko) * 2001-10-31 2005-08-17 주식회사 바이오폴리메드 펩타이드 스페이서를 갖는 생체적합성 고분자
JP4426307B2 (ja) 2002-02-08 2010-03-03 ノボザイムス アクティーゼルスカブ フィターゼ変異体
FR2840215B1 (fr) * 2002-06-03 2004-08-27 Oreal Composition contenant un actif susceptible d'etre oxyde par un hydroperoxyde, une lipoxygenase et un substrat et procede mettant en oeuvre cette composition
EP1639107B1 (de) 2003-06-19 2013-08-14 Novozymes A/S Verbesserte proteasen und methoden zu deren herstellung
WO2004111221A1 (en) 2003-06-19 2004-12-23 Novozymes A/S Proteases
EP2284259A3 (de) 2003-10-10 2011-06-15 Novozymes A/S Proteasen
ES2545494T3 (es) 2004-06-21 2015-09-11 Novozymes A/S Proteasas
DE102004041570A1 (de) * 2004-08-26 2006-03-02 Henkel Kgaa Mittel zur enzymatischen Vorbehandlung zu färbender keratinischer Fasern
US7816115B2 (en) * 2004-09-21 2010-10-19 Novozymes A/S Subtilases
US7741095B2 (en) * 2004-09-21 2010-06-22 Novozymes A/S Subtilases
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
EP1809747B1 (de) 2004-10-04 2016-12-14 Novozymes A/S Polypeptide mit phytaseaktivität und dafür codierende polynukleotide
EP1700904A1 (de) 2005-03-11 2006-09-13 Unilever N.V. Flüssige Waschmittelzusammensetzung
EP1700907A1 (de) 2005-03-11 2006-09-13 Unilever N.V. Flüssige bleichmittelzusammensetzung
DK1931702T3 (da) 2005-10-05 2013-04-15 Commw Scient Ind Res Org Silkeproteiner
US7776339B2 (en) 2006-01-11 2010-08-17 Active Organics, Lp Extract of R. miehei
WO2007107573A1 (en) 2006-03-22 2007-09-27 Novozymes A/S Use of polypeptides having antimicrobial activity
ES2531434T3 (es) 2006-04-04 2015-03-16 Novozymes A/S Variantes de fitasa
US9017664B2 (en) 2006-12-15 2015-04-28 Lifebond Ltd. Gelatin-transglutaminase hemostatic dressings and sealants
MX2009006597A (es) 2006-12-21 2009-07-02 Novozymes As Variantes de lipasa para uso farmaceutico.
US8221743B2 (en) 2006-12-22 2012-07-17 Novozymes A/S Use of polypeptides against diseases caused by protozoans
PL2129781T3 (pl) 2007-03-26 2014-07-31 Novozymes As Fitaza z Hafnia
ES2330291B1 (es) * 2008-02-29 2010-10-18 Lipotec Sa Peptidos utiles en el tratamiento de la piel, mucosas y/o cuero cabelludo y su uso en composiciones cosmeticas o farmaceuticas.
EP2303344A2 (de) * 2008-06-18 2011-04-06 Lifebond Ltd Verfahren und vorrichtungen zur verwendung mit dichtungsmitteln
CN104031393B (zh) 2008-06-18 2017-08-01 生命连结有限公司 改进的交联组合物
US20110086014A1 (en) * 2008-06-18 2011-04-14 Ishay Attar Method for enzymatic cross-linking of a protein
ES2426717T3 (es) 2008-09-26 2013-10-24 Novozymes A/S Variantes de fitasa de Hafnia
US20100316764A1 (en) * 2009-06-10 2010-12-16 Engrain, LLC Flour supplement compositions and methods for preparing wheat flour
BR112012004268B1 (pt) 2009-08-26 2021-03-02 Commonwealth Scientific And Industrial Research Organisation processos para produção de dope de seda
EP2515957B1 (de) 2009-12-22 2015-07-29 Lifebond Ltd Modifizierung von enzymatischen vernetzern zur steuerung der eigenschaften vernetzter matrizen
AU2011287215B2 (en) 2010-08-05 2015-09-10 Lifebond Ltd. Dry composition wound dressings and adhesives
WO2013071356A1 (en) 2011-11-16 2013-05-23 Commonwealth Scientific And Industrial Research Organisation Collagen-like silk genes
WO2013142901A1 (en) 2012-03-26 2013-10-03 Commonwealth Scientific And Industrial Research Organisation Silk polypeptides
CN108690841B (zh) * 2018-02-08 2021-10-01 河南科技学院 一种mPEG-Mal5000修饰β-淀粉酶的方法
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
EP4196575A1 (de) 2020-08-13 2023-06-21 Novozymes A/S Phytasevarianten und polynukleotide zur codierung davon

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2215539C2 (de) * 1972-03-30 1984-08-02 Bayer Ag, 5090 Leverkusen Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4640835A (en) * 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
JP2521504B2 (ja) * 1985-12-27 1996-08-07 昭和電工株式会社 酵素の造粒法
US5216131A (en) * 1989-02-23 1993-06-01 Genentech, Inc. Lymphocyte homing receptors
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
DE3929531A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Proteasegen aus bacillus thermoproteolyticus rokko, verfahren zu seiner gewinnung und seine verwendung
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
CA2101361A1 (en) * 1992-08-27 1994-02-28 Robert A. Snow Low diol polyalkylene oxide biologically active proteinaceous substances
DE4231266A1 (de) * 1992-09-18 1994-03-24 Boehringer Mannheim Gmbh Dextran modifizierte Glutamat-Dehydrogenase
CA2206852A1 (en) * 1994-12-07 1996-06-13 Novo Nordisk A/S Polypeptide with reduced allergenicity
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces

Also Published As

Publication number Publication date
AU751880B2 (en) 2002-08-29
CN1265142A (zh) 2000-08-30
EP1002064B1 (de) 2007-10-10
EP1002064A1 (de) 2000-05-24
DK1002064T3 (da) 2008-02-04
CN100335624C (zh) 2007-09-05
WO1999000489A1 (en) 1999-01-07
AU8012298A (en) 1999-01-19
JP2002516615A (ja) 2002-06-04
DE69838551D1 (de) 2007-11-22
DE69838551T2 (de) 2008-07-24
ES2296336T3 (es) 2008-04-16
US6303752B1 (en) 2001-10-16
CA2294567A1 (en) 1999-01-07

Similar Documents

Publication Publication Date Title
DE69838551D1 (de) Modifiziertes polypeptid
ATE234867T1 (de) Reaktionsprodukte von hyaluronsäure und natürlichen aminosäuren sowie deren verwendung in kosmetischen und pharmazeutischen zusammensetzungen
GB2314840B (en) Oxidized oligosaccharides and pharmaceutical compositions
AU4162400A (en) Derivatives of the b or z domain from staphylococcal protein a (spa) interactingwith at least one domain of human factor viii
PT749317E (pt) Aplicacoes terapeuticas de produtos dimericos de proteinas bactericidas indutoras da permeabilidade
BR9815580A (pt) Composição de vacina, processos para gerar uma resposta de anti-idiótipo em um sujeito, para tratar ou prevenir câncer, para tratar ou prevenir uma doença infecciosa, para preparar uma primeira molécula de imunoglobulina, e, primeira molécula de imunoglobulina
ATE125867T1 (de) Fibronektinbindungsprotein und dessen herstellung.
ATE236655T1 (de) Ionische molekularkonjugate von bioabbaubaren polyestern und bioaktiven polypeptiden
DE69333951D1 (de) Rekombinantes pseudomonas exotoxin mit gesteigerter aktivität
DE69533987D1 (de) Protein oder polypeptid, verfahren zur seiner herstellung und entsprechende zwischenprodukte
ATE221083T1 (de) Glialmitogene faktoren, ihre herstellung und verwendung
PL336347A1 (en) Oil-in-water emulsions containing a derivative of 1,3,5-triazine and a silicone polyalcohol as well as their cosmetic applications
DE69839939D1 (de) Tropoelastinderivate
ES2103408T3 (es) Analogos de oligorribonucleotidos y ribozimas con uniones terminales en 3'-3' o 5'-5' respectivamente.
AU8040898A (en) Type-1 ribosome-inactivating protein
ATE276358T1 (de) Polypeptid-polymer konjugat
ATE139541T1 (de) Kollagen-bindendes protein sowie dessen herstellung
DE69524971D1 (de) Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen
DE69832216D1 (de) Rantes Mutanten und deren therapeutischen Anwendungen
ATE125270T1 (de) Tert-butyloxycarbonyl-l-tyrosyl- peptidoglycanmonomer und deren 125 i-markiertes derivat, deren herstellung und verwendung.
DE69534738D1 (de) Leukocyten-aktivierender Faktor
BR9008053A (pt) Ionômero de amidas de copolímero de baixo peso molecular, composição incluindo o mesmo, e produto de reação do mesmo.
ATE130872T1 (de) Ancrod ähnliche proteine, ihre herstellung und verwendung.
DE69427595D1 (de) Antitumormittel auf basis von carboplatin und herstellung desselben
IT1264129B1 (it) Peptidi ad attivita' immunomodulatoria derivati da frammenti di leucochinina

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties