ATE347556T1 - Verwendung von kondensierten pyrazolverbindungen für die herstellung eines arzneimittels zur behandlung von bluthochdruck - Google Patents
Verwendung von kondensierten pyrazolverbindungen für die herstellung eines arzneimittels zur behandlung von bluthochdruckInfo
- Publication number
- ATE347556T1 ATE347556T1 AT03078987T AT03078987T ATE347556T1 AT E347556 T1 ATE347556 T1 AT E347556T1 AT 03078987 T AT03078987 T AT 03078987T AT 03078987 T AT03078987 T AT 03078987T AT E347556 T1 ATE347556 T1 AT E347556T1
- Authority
- AT
- Austria
- Prior art keywords
- hypertension
- treatment
- production
- medicinal product
- pyrazole compounds
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical class C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 2
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 2
- 102000007637 Soluble Guanylyl Cyclase Human genes 0.000 abstract 2
- 108010007205 Soluble Guanylyl Cyclase Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 pyrazolyl compound Chemical class 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26378201P | 2001-01-24 | 2001-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE347556T1 true ATE347556T1 (de) | 2006-12-15 |
Family
ID=23003205
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03078987T ATE347556T1 (de) | 2001-01-24 | 2002-01-24 | Verwendung von kondensierten pyrazolverbindungen für die herstellung eines arzneimittels zur behandlung von bluthochdruck |
| AT02250490T ATE282622T1 (de) | 2001-01-24 | 2002-01-24 | Kondensierte pyrazolverbindungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02250490T ATE282622T1 (de) | 2001-01-24 | 2002-01-24 | Kondensierte pyrazolverbindungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6518294B2 (de) |
| EP (1) | EP1227099B1 (de) |
| CN (1) | CN1393446B (de) |
| AT (2) | ATE347556T1 (de) |
| CA (1) | CA2369232C (de) |
| DE (2) | DE60201921T2 (de) |
| TW (1) | TWI250161B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040077702A1 (en) * | 2001-09-14 | 2004-04-22 | Wen-Mei Fu | Treatment of nuerodegenerative diseases |
| US7345079B2 (en) * | 2001-12-26 | 2008-03-18 | Yung Shin Pharmaceuticals Industrial Co., Ltd | Treatment of disorder related to low cyclic GMP levels |
| WO2003061651A1 (en) * | 2002-01-22 | 2003-07-31 | The Regents Of The University Of California | Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof |
| US7166293B2 (en) * | 2002-03-29 | 2007-01-23 | Carlsbad Technology, Inc. | Angiogenesis inhibitors |
| US20050096370A1 (en) * | 2003-04-07 | 2005-05-05 | Bizbiotech Co., Ltd. | Method for inhibiting tumor angiogenesis and tumor growth |
| US7226941B2 (en) | 2003-06-30 | 2007-06-05 | Hif Bio, Inc. | Compound for treating angiogenesis |
| AR046890A1 (es) * | 2003-12-15 | 2005-12-28 | Alcon Inc | [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma. |
| GB0405933D0 (en) * | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
| CN100516049C (zh) * | 2004-11-16 | 2009-07-22 | 永信药品工业股份有限公司 | 抗血管生成药n2-(取代的芳基甲基)-3-(取代的苯基)吲唑的合成 |
| CA2620275A1 (en) * | 2005-08-26 | 2007-03-01 | Thomas S. Scanlan | Non-steroidal antiandrogens |
| US20080252028A1 (en) * | 2007-04-16 | 2008-10-16 | Ming-Tai Huang | Shock absorbing device for toy stroller |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
| DE19642255A1 (de) | 1996-10-14 | 1998-04-16 | Bayer Ag | Verwendung von 1-Benzyl-3-(substituierten-hetaryl) -kondensierten Pyrazol-Derivaten |
| IT1295384B1 (it) | 1997-10-23 | 1999-05-12 | Snam Progetti | Rivestimento protettivo di apparecchiature a pressione utilizzabili in processi per la sintesi dell'urea |
| US6387942B2 (en) * | 2000-06-19 | 2002-05-14 | Yung Shin Pharmaceutical Ind. Co. Ltd | Method of treating disorders related to protease-activated receptors-induced cell activation |
-
2002
- 2002-01-24 US US10/057,079 patent/US6518294B2/en not_active Expired - Fee Related
- 2002-01-24 DE DE60201921T patent/DE60201921T2/de not_active Expired - Fee Related
- 2002-01-24 TW TW091101179A patent/TWI250161B/zh not_active IP Right Cessation
- 2002-01-24 EP EP02250490A patent/EP1227099B1/de not_active Expired - Lifetime
- 2002-01-24 AT AT03078987T patent/ATE347556T1/de not_active IP Right Cessation
- 2002-01-24 CA CA2369232A patent/CA2369232C/en not_active Expired - Fee Related
- 2002-01-24 DE DE60216610T patent/DE60216610T2/de not_active Expired - Fee Related
- 2002-01-24 AT AT02250490T patent/ATE282622T1/de not_active IP Right Cessation
- 2002-01-24 CN CN021004625A patent/CN1393446B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60201921T2 (de) | 2005-10-06 |
| US20030004355A1 (en) | 2003-01-02 |
| CA2369232C (en) | 2010-05-25 |
| ATE282622T1 (de) | 2004-12-15 |
| US6518294B2 (en) | 2003-02-11 |
| CN1393446B (zh) | 2010-06-16 |
| HK1050194A1 (zh) | 2003-06-13 |
| DE60216610T2 (de) | 2007-10-11 |
| EP1227099B1 (de) | 2004-11-17 |
| DE60216610D1 (de) | 2007-01-18 |
| TWI250161B (en) | 2006-03-01 |
| EP1227099A1 (de) | 2002-07-31 |
| CA2369232A1 (en) | 2002-07-24 |
| DE60201921D1 (de) | 2004-12-23 |
| CN1393446A (zh) | 2003-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |