ATE345345T1 - Thieno(2,3-d)pyrimidine mit kombinierter lh und fsh agonistischen wirkung - Google Patents

Thieno(2,3-d)pyrimidine mit kombinierter lh und fsh agonistischen wirkung

Info

Publication number: ATE345345T1
Authority: AT; Austria
Prior art keywords: thieno; pyrimidines; combined; agonistic effects; fsh agonistic
Prior art date: 2001-09-04

Application number

AT02772230T

Other languages

English (en)

Inventor

Robert Gerard Jules Ma Hanssen

Cornelis Marius Timmers

Original Assignee

Organon Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-04

Filing date

2002-08-29

Publication date

2006-12-15

2002-08-29 Application filed by Organon Nv filed Critical Organon Nv

2006-12-15 Application granted granted Critical

2006-12-15 Publication of ATE345345T1 publication Critical patent/ATE345345T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT02772230T 2001-09-04 2002-08-29 Thieno(2,3-d)pyrimidine mit kombinierter lh und fsh agonistischen wirkung ATE345345T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01203327		2001-09-04

Publications (1)

Publication Number	Publication Date
ATE345345T1 true ATE345345T1 (de)	2006-12-15

Family

ID=8180876

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02772230T ATE345345T1 (de)	2001-09-04	2002-08-29	Thieno(2,3-d)pyrimidine mit kombinierter lh und fsh agonistischen wirkung

Country Status (28)

Country	Link
US (1)	US7317006B2 (de)
EP (1)	EP1427733B1 (de)
JP (1)	JP4262092B2 (de)
KR (1)	KR100900018B1 (de)
CN (1)	CN1246324C (de)
AR (1)	AR036407A1 (de)
AT (1)	ATE345345T1 (de)
AU (1)	AU2002337035B2 (de)
BR (1)	BR0211938A (de)
CA (1)	CA2456901C (de)
CY (1)	CY1106012T1 (de)
DE (1)	DE60216128T2 (de)
DK (1)	DK1427733T3 (de)
ES (1)	ES2275005T3 (de)
HR (1)	HRP20040202A2 (de)
HU (1)	HUP0401444A3 (de)
IL (1)	IL160084A0 (de)
IS (1)	IS2424B (de)
MX (1)	MXPA04002045A (de)
NO (1)	NO20040927L (de)
NZ (1)	NZ531340A (de)
PE (1)	PE20030439A1 (de)
PL (1)	PL368502A1 (de)
PT (1)	PT1427733E (de)
RU (1)	RU2298011C2 (de)
TW (1)	TWI228508B (de)
WO (1)	WO2003020726A1 (de)
ZA (1)	ZA200401455B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6890923B2 (en) *	2002-12-16	2005-05-10	Astrazeneca Ab	Compounds
GB0315950D0 (en) *	2003-06-11	2003-08-13	Xention Discovery Ltd	Compounds
GB0525164D0 (en) *	2005-12-09	2006-01-18	Xention Discovery Ltd	Compounds
CN100430403C (zh) *	2006-10-13	2008-11-05	中国科学院上海有机化学研究所	3-芳基-5,6-取代噻吩并嘧啶-4-羰基-2-巯基乙腈、合成方法和用途
US20090118276A1 (en) *	2007-11-02	2009-05-07	Wyeth	Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors
TWI389913B (zh) *	2008-09-08	2013-03-21	Lg Life Sciences Ltd	并合雜環化合物
WO2010047674A1 (en)	2008-10-20	2010-04-29	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Low molecular weight thyroid stimulating hormone receptor (tshr) agonists
GB0905525D0 (en)	2009-03-31	2009-05-13	Univ Leiden	Compounds and uses
EA022553B1 (ru)	2010-01-22	2016-01-29	Байер Интеллектуэль Проперти Гмбх	Применение комбинации биологически активных веществ, набор и средство, содержащие комбинацию биологически активных веществ, для борьбы с вредителями животного происхождения и способ улучшения использования продукционного потенциала трансгенного растения
EP2563777A4 (de)	2010-04-08	2013-09-04	Us Health	Inverse agonisten und neutrale agonisten für den tsh-rezeptor
RU2619091C2 (ru) *	2015-10-13	2017-05-11	Министерство Промышленности И Торговли Рф	Цилиндрический термоэмиссионный катод
AU2023282849A1 (en) *	2022-06-08	2025-01-09	Icahn School Of Medicine At Mount Sinai	Method of treating obesity with a luteinizing hormone receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3879031T2 (de)	1987-08-08	1993-06-24	Akzo Nv	Kontrazeptives implantat.
TW564247B (en) *	1999-04-08	2003-12-01	Akzo Nobel Nv	Bicyclic heteraromatic compound

2002
- 2002-07-22 TW TW091116284A patent/TWI228508B/zh not_active IP Right Cessation
- 2002-08-29 NZ NZ531340A patent/NZ531340A/en unknown
- 2002-08-29 HU HU0401444A patent/HUP0401444A3/hu unknown
- 2002-08-29 US US10/488,482 patent/US7317006B2/en not_active Expired - Lifetime
- 2002-08-29 AT AT02772230T patent/ATE345345T1/de not_active IP Right Cessation
- 2002-08-29 KR KR1020047003095A patent/KR100900018B1/ko not_active IP Right Cessation
- 2002-08-29 PT PT02772230T patent/PT1427733E/pt unknown
- 2002-08-29 AU AU2002337035A patent/AU2002337035B2/en not_active Ceased
- 2002-08-29 DE DE60216128T patent/DE60216128T2/de not_active Expired - Lifetime
- 2002-08-29 RU RU2004110042/04A patent/RU2298011C2/ru not_active IP Right Cessation
- 2002-08-29 ES ES02772230T patent/ES2275005T3/es not_active Expired - Lifetime
- 2002-08-29 PL PL02368502A patent/PL368502A1/xx not_active Application Discontinuation
- 2002-08-29 MX MXPA04002045A patent/MXPA04002045A/es active IP Right Grant
- 2002-08-29 WO PCT/EP2002/009647 patent/WO2003020726A1/en active IP Right Grant
- 2002-08-29 JP JP2003524996A patent/JP4262092B2/ja not_active Expired - Fee Related
- 2002-08-29 IL IL16008402A patent/IL160084A0/xx not_active IP Right Cessation
- 2002-08-29 DK DK02772230T patent/DK1427733T3/da active
- 2002-08-29 EP EP02772230A patent/EP1427733B1/de not_active Expired - Lifetime
- 2002-08-29 BR BR0211938-2A patent/BR0211938A/pt not_active IP Right Cessation
- 2002-08-29 CA CA2456901A patent/CA2456901C/en not_active Expired - Fee Related
- 2002-08-29 CN CNB028172604A patent/CN1246324C/zh not_active Expired - Fee Related
- 2002-09-02 AR ARP020103309A patent/AR036407A1/es unknown
- 2002-09-03 PE PE2002000840A patent/PE20030439A1/es not_active Application Discontinuation
2004
- 2004-01-29 IS IS7130A patent/IS2424B/is unknown
- 2004-02-23 ZA ZA200401455A patent/ZA200401455B/en unknown
- 2004-03-01 HR HR20040202A patent/HRP20040202A2/hr not_active Application Discontinuation
- 2004-03-03 NO NO20040927A patent/NO20040927L/no not_active Application Discontinuation
2007
- 2007-02-13 CY CY20071100189T patent/CY1106012T1/el unknown

Also Published As

Publication number	Publication date
EP1427733B1 (de)	2006-11-15
IS7130A (is)	2004-01-29
CA2456901C (en)	2011-01-04
AR036407A1 (es)	2004-09-08
PE20030439A1 (es)	2003-05-17
WO2003020726A1 (en)	2003-03-13
PL368502A1 (en)	2005-04-04
HRP20040202A2 (en)	2004-08-31
JP2005505555A (ja)	2005-02-24
JP4262092B2 (ja)	2009-05-13
CY1106012T1 (el)	2011-04-06
RU2004110042A (ru)	2005-08-20
ZA200401455B (en)	2004-11-19
KR100900018B1 (ko)	2009-06-01
CN1246324C (zh)	2006-03-22
AU2002337035B2 (en)	2008-04-24
NZ531340A (en)	2005-08-26
US7317006B2 (en)	2008-01-08
ES2275005T3 (es)	2007-06-01
DE60216128D1 (de)	2006-12-28
RU2298011C2 (ru)	2007-04-27
HUP0401444A3 (en)	2008-05-28
IS2424B (is)	2008-10-15
PT1427733E (pt)	2007-02-28
DE60216128T2 (de)	2007-09-27
DK1427733T3 (da)	2007-03-19
NO20040927L (no)	2004-03-03
CA2456901A1 (en)	2003-03-13
MXPA04002045A (es)	2004-07-08
KR20040029134A (ko)	2004-04-03
BR0211938A (pt)	2004-09-21
TWI228508B (en)	2005-03-01
US20040180873A1 (en)	2004-09-16
HUP0401444A2 (hu)	2004-11-29
IL160084A0 (en)	2004-06-20
CN1551884A (zh)	2004-12-01
EP1427733A1 (de)	2004-06-16

Publication	Publication Date	Title
EP1401840A4 (de)	2007-05-16	Neue 4-amino-5,6-substituierte thiopheno 2,3 d\|pyrimidine
NO20034929L (no)	2003-11-05	4-amino-5-fenyl-7-cyklobutylpyrrol(2,3-D)pyrimidinderivater
ATE388713T1 (de)	2008-03-15	4-amino-6-phenyl-pyrrolo(2,3-d)pyrimidin derivate
NO20042676L (no)	2004-08-24	3-beta-d-ribofuranolsyltiazolo[4,5-d]pyrimidinnukleosider og anvendelser derav
NO20022738L (no)	2002-06-07	Pyrrolo(2,3-d)pyrimidinforbindelser
ATE284872T1 (de)	2005-01-15	4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer wirkung
DZ3308A1 (de)	2001-09-27	5-alkylpyrido [2,3-d] pyrimidin tyrosine kinase inhibitoren
ATE387446T1 (de)	2008-03-15	Pyrido(2,3-d)pyrimidin-2,4-diamine als pde-2- inhibitoren
HK1087108A1 (en)	2006-10-06	5,7-diaminopyrazolo[4,3-d] pyrimidines useful in the treatment of hypertension
ATE345345T1 (de)	2006-12-15	Thieno(2,3-d)pyrimidine mit kombinierter lh und fsh agonistischen wirkung
HUP0401684A3 (en)	2005-06-28	Nicotinic acid-heterocyclyl-amides and analogous pyrimidine derivatives serving as pesticides
DE60205921D1 (de)	2005-10-06	SUBSTITUIERTE 2-PYRIDINYL-6,7,8,9-TETRAHYDROPYRIMIDOç1,2-A!PYRIMIDIN-4-ON- UND 7-PYRIDINYL-2,3-DIHYDROIMIDAZO-ç1,2-A!PYRIMIDIN-5(1H)ONDERIVATE
ATE231866T1 (de)	2003-02-15	Pyrazolo(4, 3-d)pyrimidine
ATE309251T1 (de)	2005-11-15	Glycinsubstituierte thieno(2,3-d)pyrimidine mit kombinierter lh- und fsh-agonistischer wirkung
HUP0303005A3 (en)	2005-05-30	Pharmaceutical compositions comprising pyrazolo[4,3-d]pyrimidines or thienopyrimidines and endothelin receptor antagonists
NO20040990L (no)	2004-03-08	Andvendelse av LH i kontrollert ovariehyperstimulering.
ATE276260T1 (de)	2004-10-15	2-aminoalkyl-thieno(2,3-d)pyrimidine
DE50106542D1 (de)	2005-07-21	Substituierte 3,4-dihydro-pyrido[1,2-a]pyrimidine
AU2002305292A1 (en)	2002-11-11	Novel 4-amino-5,6-substituted thiopheno(2,3-d)pyrimidines
DK1326866T3 (da)	2005-08-01	Substituerede 3,4-dihydro-pyrido[1,2-a]pyrimidiner
DK1325010T3 (da)	2005-05-17	Substituerede 3,4-dihydro-pyrimido[1,2-a]pyrimidiner og 3,4-dihydro-pyrazino[1,2-a]pyrimidiner

Legal Events

Date	Code	Title	Description
2007-07-15	UEP	Publication of translation of european patent specification	Ref document number: 1427733 Country of ref document: EP
2010-05-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2007-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1427733

Country of ref document: EP

2010-05-15

REN

Ceased due to non-payment of the annual fee