ATE334203T1 - Verfahren zur herstellung von sekundären metaboliten - Google Patents

Verfahren zur herstellung von sekundären metaboliten

Info

Publication number: ATE334203T1
Authority: AT; Austria
Prior art keywords: microorganism; secondary metabolite; pct; metabolite; producing
Prior art date: 1994-09-28

Application number

AT95931924T

Other languages

English (en)

Inventor

Michi Egel-Mitani

Henrik Moellgaard

Svend Kaasgaard

Klaus Nyegaard Kristiansen

Original Assignee

Novozymes As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-28

Filing date

1995-09-28

Publication date

2006-08-15

1995-09-28 Application filed by Novozymes As filed Critical Novozymes As

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE334203T1 publication Critical patent/ATE334203T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Mycology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT95931924T 1994-09-28 1995-09-28 Verfahren zur herstellung von sekundären metaboliten ATE334203T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK111894		1994-09-28

Publications (1)

Publication Number	Publication Date
ATE334203T1 true ATE334203T1 (de)	2006-08-15

Family

ID=8101219

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95931924T ATE334203T1 (de)	1994-09-28	1995-09-28	Verfahren zur herstellung von sekundären metaboliten

Country Status (7)

Country	Link
US (1)	US5882883A (de)
EP (1)	EP0783581B1 (de)
JP (1)	JP3764166B2 (de)
AT (1)	ATE334203T1 (de)
AU (1)	AU3517895A (de)
DE (1)	DE69535126D1 (de)
WO (1)	WO1996010084A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6495348B1 (en)	1993-10-07	2002-12-17	Regents Of The University Of Minnesota	Mitomycin biosynthetic gene cluster
US6524812B1 (en)	1993-10-07	2003-02-25	Regents Of The University Of Minnesota	Genes encoding resistance to DNA alkylating agents
WO1997022711A1 (en)	1995-12-19	1997-06-26	Regents Of The University Of Minnesota	Metabolic engineering of polyhydroxyalkanoate monomer synthases
US7390619B1 (en) *	1998-02-11	2008-06-24	Maxygen, Inc.	Optimization of immunomodulatory properties of genetic vaccines
US6541011B2 (en)	1998-02-11	2003-04-01	Maxygen, Inc.	Antigen library immunization
US6451564B1 (en) *	1999-07-02	2002-09-17	Massachusetts Institute Of Technology	Methods for producing L-isoleucine
US6284483B1 (en) *	1999-10-06	2001-09-04	Board Of Trustees Operating Michigan State University	Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate
JP2020162549A (ja)	2019-03-29	2020-10-08	味の素株式会社	制御装置、制御方法およびプログラムならびに有機化合物の製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL78531A0 (en) *	1985-04-22	1986-08-31	Lilly Co Eli	Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase
RU1780542C (ru) *	1985-04-22	1992-12-07	Эли Лилли Энд Компани	Способ конструировани рекомбинантной плазмидной ДНК pPS 20, кодирующей изопенициллин-N-синтетазу, способ получени штамма СернаLоSроRIUм асRемоNIUм, обладающего активностью изопенициллин-N-синтетазы
US4892819A (en) *	1985-11-25	1990-01-09	Eli Lilly And Company	Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum
ES2061483T3 (es) *	1986-09-16	1994-12-16	Gist Brocades Nv	Cepa de penicillium transformada y metodo para la transformacion de una celula huesped de penicillium.
FI104264B1 (fi) *	1988-08-11	1999-12-15	Dsm Nv	Menetelmä sekundääristen metaboliittien tuoton parantamiseksi käyttämällä rykelmöityjä biosynteettisiä geenejä
FI104984B (fi) *	1988-08-11	2000-05-15	Dsm Nv	Menetelmä biosynteettisten tai säätelygeenien identifioimiseksi ja käyttämiseksi sekundääristen metaboliittien tuoton parantamiseksi
US5108918A (en) *	1988-08-11	1992-04-28	Gist-Brocades	Method for identifying and using biosynthetic genes for enhanced production of secondary metabolites
ATE118042T1 (de) *	1988-12-22	1995-02-15	Lilly Co Eli	Rekombinante dna enthaltende expressionsvektoren und für isopenicillin-n-epimerase-(racemase)- aktivität kodierende dns-verbindungen.
FR2642768B1 (fr) *	1989-01-19	1991-05-17	Transgene Sa	Procede perfectionne pour l'expression de la biotine dans bacillus sphaericus
IL95766A (en) *	1989-09-27	1996-12-05	Lilly Co Eli	Recombinant DNA expression vectors And DNA compounds. Which encode Aspergillus acyltransferase activity
PT97116B (pt) *	1990-03-23	1998-10-30	Gist Brocades Nv	Processo para modular a producao de metabolitos secundarios nomeadamente derivados de beta-lactama
RO116648B1 (ro) *	1991-10-15	2001-04-30	Merck & Co Inc	Bioprocedeu pentru prepararea acidului 7-amino-3-deacetil-cefalosporanic si a acidului 7-aminocefalosporanic
KR100336174B1 (ko) *	1993-07-30	2002-11-01	디에스엠 기스트 베.파우.	2-(카르복시에틸티오)아세틸-7-adca및3-(카르복시메틸티오)프로피오닐-7-adca를경유하여7-adca를제조하는효율적인방법
US5474912A (en) *	1994-03-03	1995-12-12	Sherman; David H.	Method for increasing production of microbial metabolites by genetic engineering

1995
- 1995-09-28 JP JP51129196A patent/JP3764166B2/ja not_active Expired - Fee Related
- 1995-09-28 WO PCT/DK1995/000386 patent/WO1996010084A1/en active IP Right Grant
- 1995-09-28 AT AT95931924T patent/ATE334203T1/de not_active IP Right Cessation
- 1995-09-28 AU AU35178/95A patent/AU3517895A/en not_active Abandoned
- 1995-09-28 EP EP95931924A patent/EP0783581B1/de not_active Expired - Lifetime
- 1995-09-28 DE DE69535126T patent/DE69535126D1/de not_active Expired - Lifetime
- 1995-09-28 US US08/793,786 patent/US5882883A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0783581B1 (de)	2006-07-26
JP3764166B2 (ja)	2006-04-05
JPH10506283A (ja)	1998-06-23
WO1996010084A1 (en)	1996-04-04
EP0783581A1 (de)	1997-07-16
AU3517895A (en)	1996-04-19
DE69535126D1 (de)	2006-09-07
US5882883A (en)	1999-03-16

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Legal Events

Date	Code	Title	Description
2007-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties