[go: up one dir, main page]

ATE332974T1 - Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung - Google Patents

Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung

Info

Publication number
ATE332974T1
ATE332974T1 AT97928639T AT97928639T ATE332974T1 AT E332974 T1 ATE332974 T1 AT E332974T1 AT 97928639 T AT97928639 T AT 97928639T AT 97928639 T AT97928639 T AT 97928639T AT E332974 T1 ATE332974 T1 AT E332974T1
Authority
AT
Austria
Prior art keywords
itak
tnf
alpha
production
activated kinase
Prior art date
Application number
AT97928639T
Other languages
English (en)
Inventor
John E Sims
G Duke Virca
Timothy A Bird
Dirk M Anderson
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE332974T1 publication Critical patent/ATE332974T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT97928639T 1996-06-10 1997-06-09 Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung ATE332974T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63341496A 1996-06-10 1996-06-10

Publications (1)

Publication Number Publication Date
ATE332974T1 true ATE332974T1 (de) 2006-08-15

Family

ID=24539544

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97928639T ATE332974T1 (de) 1996-06-10 1997-06-09 Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung

Country Status (14)

Country Link
EP (1) EP0914451B1 (de)
JP (1) JP2000512147A (de)
KR (1) KR20000016286A (de)
AT (1) ATE332974T1 (de)
AU (1) AU718792B2 (de)
CA (1) CA2257373A1 (de)
DE (1) DE69736326T2 (de)
DK (1) DK0914451T3 (de)
ES (1) ES2270463T3 (de)
IL (1) IL127363A (de)
NO (1) NO985742L (de)
NZ (1) NZ333214A (de)
PT (1) PT914451E (de)
WO (1) WO1997047750A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000036097A2 (en) * 1998-12-18 2000-06-22 Immunex Corporation Methods for regulating vascularization using gef containing nek-like kinase (gnk)
EP1180151A2 (de) * 1999-05-28 2002-02-20 Sugen, Inc. Proteinkinasen
CA2385169A1 (en) * 1999-09-27 2001-04-05 Human Genome Sciences, Inc. 43 human secreted proteins
US6911336B2 (en) 2000-10-18 2005-06-28 Immunex Corporation GNK interacting amino acid decarboxylase and methods of use thereof
WO2003077875A2 (en) * 2002-03-15 2003-09-25 Incyte Corporation Proteins associated with growth, differentiation, and death
JP2006512048A (ja) * 2002-06-11 2006-04-13 ザ・ジェネラル・ホスピタル・コーポレイション 有糸分裂の阻害剤の同定
US7371364B2 (en) 2003-08-15 2008-05-13 Board Of Regents, The University Of Texas System Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741667A (en) * 1994-05-27 1998-04-21 Genentech, Inc. Tumor necrosis factor receptor-associated factors

Also Published As

Publication number Publication date
CA2257373A1 (en) 1997-12-18
KR20000016286A (ko) 2000-03-25
NO985742L (no) 1999-02-10
EP0914451A1 (de) 1999-05-12
PT914451E (pt) 2006-12-29
AU3284297A (en) 1998-01-07
ES2270463T3 (es) 2007-04-01
DE69736326D1 (de) 2006-08-24
AU718792B2 (en) 2000-04-20
DK0914451T3 (da) 2006-11-13
EP0914451B1 (de) 2006-07-12
IL127363A (en) 2007-05-15
IL127363A0 (en) 1999-10-28
JP2000512147A (ja) 2000-09-19
DE69736326T2 (de) 2007-07-19
WO1997047750A1 (en) 1997-12-18
NO985742D0 (no) 1998-12-08
NZ333214A (en) 2000-02-28

Similar Documents

Publication Publication Date Title
DE69941701D1 (de) Mutanten von flt3-l und ihre verwendungen
DE3878326D1 (de) Kunstlunge der membranart und verfahren zu ihrer verwendung.
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
DE3678857D1 (de) Keramikverbundkoerper und verfahren zu ihrer herstellung.
DE3689195D1 (de) Verfahren zur Herstellung von Aloe-Erzeugnissen, Erzeugnisse und Zusammensetzungen dazu.
DE68914664D1 (de) Gereinigte ubiquitin-hydrolase, diese kodierende dns-sequenzen und ihre verwendung zur gewinnung von polypeptiden.
DE69931479D1 (de) Verfahren zur herstellung von polypeptiden in einem zellfreien system und vorrichtung zu deren ausführung
DE58907088D1 (de) Verfahren zur Trennung von Folinsäure.
DE69823662D1 (de) 1,4,7,10-tetraazabicyclo(8.2.2)tetradecan-2-on, verfahren zu ihrer herstellung und ihrer verwendung für die herstellung von tetraazamacrocyclen
DE3670080D1 (de) Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika.
DE19983660T1 (de) Verfahren zur Aufreinigung von Lösungsmitteln, die bei der Herstellung von pharmazeutischen Zusammensetzungen nützlich sind
ATE332974T1 (de) Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung
DK0700437T3 (da) DNA, der koder for prostaglandin-receptor EP1
DE3789569D1 (de) Zementzusammensetzung und Verfahren zu ihrer Herstellung.
DE68926025D1 (de) Methode zur Herstellung von alpha-Amylase hemmenden Substanzen aus Weizen
ATE48142T1 (de) Blutprotein, verfahren zu seiner herstellung, antikoerper gegen dieses protein und dieses protein oder diese antikoerper enthaltende pharmazeutische zubereitungen.
DE3582466D1 (de) Aminoalkohol-derivate und verfahren zu ihrer herstellung.
SE9602822D0 (sv) New receptor
DK0643719T3 (da) Nukleinsyresekvenser, som koder for eller er komplementære til nukleinsyresekvenser, som koder for interleukin 9-receptor
DE3855634D1 (de) Innerhalb des alpha-Locus gelegenes T-Zell-Rezeptor-Gen und DNA-Konstruktionen
DE3673734D1 (de) Xanthinderivate, verfahren zu ihrer herstellung und ihre verwendung als medikamente.
AR022150A1 (es) Acidos nucleicos derivados de monocitos y composiciones y metodos relacionados
DE3888018D1 (de) Substituierte Vinylcephalosporine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DE3485923D1 (de) Dna-gen, verfahren zu seiner herstellung und dieses gen enthaltendes plasmid.
ES2165358T3 (es) Utilizaciones de la proteinquinasa de neurofilamento/tau pk40.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0914451

Country of ref document: EP

REN Ceased due to non-payment of the annual fee